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Private Speech and Mutual Engagement in Preschoolers Playtime Interaction : Talk and Embodiment
김윤희(Younhee Kim) 한국사회언어학회 2018 사회언어학 Vol.26 No.2
Kim, Younhee. 2018. “Private Speech and Mutual Engagement in Preschoolers Playtime Interaction: Talk and Embodiment”. The Sociolinguistic Journal of Korea 26(2), 119~165. Preschoolers playtime interaction presents a unique context where private speech/self-talk and mutual conversation are co-present as well as within and out-of-(pretend play) frame talk. Preliminary observation of the data from the larger project revealed an overall pattern where the two children would play together and soon one child or both of them wander off to his/her own private speech/play mode, and then mutual engagement is achieved again. The current study examines this phenomenon from a conversation analytic perspective by showing what types of sequential resources are employed by the children to manage the transition. The resources include making an announcement, a noticing comment about the shared environment, repetition, code-switching, and embodied resources such as gaze, postural orientation, and spatial positioning in the play space (Kendon 1990). The transition from mutual conversation to private speech often accompanies transition from reality to pretend play talk, though not exclusively so. Making a meta-pretend play comment and making a reference to the theme of the joint play also served as an effective way to achieve re-engagement. Based on detailed interactional analysis, the study suggests that the playtime interaction of preschoolers affords more self-oriented speech (self-repair, private speech) and is characterized by rather loosened expectation for responsivity while “playing together” takes close orientation to the other child s behavior as they co-ordinate moments of mutual engagement and separate play throughout their co-presence.
Kim Chul,Kim Joong Sun,Lee Hae June,Seong Boseok,Seo Seung‐won,Son Hyojung,Jeon Ji‐Hyeon,Shin Younhee 한국곤충학회 2022 Entomological Research Vol.52 No.7
Mantidis Ootheca (MO) is the egg case of the praying mantis. MO has been used in Oriental and Chinese traditional medicine in a steamed form and is known for enhancing male fertility since ancient times. Here, we used total RNA sequencing to reveal the genome-wide differential expression profiles of mice subjected to irradiation and Tenodera angustipennis MO extract treatment to understand the therapeutic effect of MO extract on radiation-induced gonadal toxicity in mice. Approximately 225 genes exhibited differential expression patterns, among which 24 showed a reversal of expression pattern in response to irradiation and MO extract treatment. Most of these genes are associated with spermatogenesis and could be considered as candidates for further experimental studies. Considering that there is no approved radio-protective drug for treating radiation-induced damage to testicles, we would like to demonstrate the therapeutic potential of the use of MO extract as a traditional medicinal practice that can serve as a one of tool for the mitigation and treatment of gonadal toxicity.
Fisetin-Mediated Perturbations of Membrane Permeability and Intracellular pH in Candida albicans
( Younhee Kim ) 한국미생물생명공학회 2024 Journal of microbiology and biotechnology Vol.34 No.4
The antifungal activity of fisetin against Candida albicans is explored, elucidating a mechanism centered on membrane permeabilization and ensuing disruption of pH homeostasis. The Minimum Inhibitory Concentration (MIC) of fisetin, indicative of its interaction with the fungal membrane, increases in the presence of ergosterol. Hoechst 33342 and propidium-iodide staining reveal substantial propidium-iodide accumulation in fisetin-treated C. albicans cells at their MIC, with crystal violet uptake assays confirming fisetin-induced membrane permeabilization. Leakage analysis demonstrates a significant release of DNA and proteins in fisetin-treated cells compared to controls, underscoring the antifungal effect through membrane disruption. Green fluorescence, evident in both the cytoplasm and vacuoles of fisetin-treated cells under BCECF, AM staining, stands in contrast to controls where only acidic vacuoles exhibit staining. Ratiometric pH measurements using BCECF, AM reveal a noteworthy reduction in intracellular pH in fisetin-treated cells, emphasizing its impact on pH homeostasis. DiBAC<sub>4</sub>(3) uptake assays demonstrate membrane hyperpolarization in fisetintreated cells, suggesting potential disruptions in ion flux and cellular homeostasis. These results provide comprehensive insights into the antifungal mechanisms of fisetin, positioning it as a promising therapeutic agent against Candida infections.
Development of L2 Interactional Competence
Younhee Kim 담화·인지언어학회 2016 담화와 인지 Vol.23 No.1
This study investigates the development of Interactional Competence in one second language learner of English by focusing on his performance as a story recipient. Telling and listening to stories are commonplace conversational activities. Through storytelling, participants share experience and reactions to it, which makes storytelling a distinctively affiliative social action. Being a story recipient is not merely a passive job, however. By providing reactions to it, the story recipient plays a significant role in determining when the storytelling is concluded and what to make of the story. By examining one L2 English learner’s participation in storytelling activities in conversation over the period of six months using Conversation Analysis (Sacks, Schegloff and Jefferson 1974), the present study illustrates how the focal learner becomes more active and resourceful in being a story recipient.