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      • 유기주석 노출에 의한 Mysid, Neomysis awatschensis의 독성 영향

        지정훈,김상규,황운기,강주찬 한국환경독성학회 2002 환경독성보건학회지 Vol.17 No.4

        Tests for the toxicity of tributyltin (TBT) were conducted on mysid collected from Dadepo beach, Pusan, Korea. The toxic effects of tributyltin on the survival, growth and oxygen consumption of the mysid, Neomysis awatschensis have been evaluated. Mysids were exposed to several concentrations of TBT (0, 0.56, 1.15, 3.07 and 6.12 ㎍/L) for 6 weeks. Survival rate was decreased with increases in concentration and exposure time and the reduction of more than 40% occurred at TBT concentration greater than 1.15 ㎍/L after 6 weeks. Growth rate was significantly decreased at concentrations greater than 1.15 ㎍/L Oxygen consumption rate was also decreased in a concentration-dependent way and significantly decreased to 39, 47 and 69% of the control at 1. 15, 3.07 and 6.12 ㎍/L, respectively. These results indicate that the contamination of aquatic environment by TBT has the potential to significantly reduce coastal and estuaries recruitment of mysid.

      • UV/H2O2 광산화공정을 적용한 원전 발생 방사성 폐액내 세제 처리

        박은정,이지훈,박세문 대구대학교 환경기술연구소 2004 미래환경기술 Vol.1 No.1

        원전 발생 방사성 폐액 내 세제를 제거하기 위한 전처리 공정으로 UV 광산화 공정을 활용하기 위하여 공정의 효율 및 적용 가능성에 대한 기초 실험을 수행하였다. 최적 처리조건을 도출하고자, 방사성 폐액의 평균 세제 함유량 (TOC 50∼100ppm)을 기준으로 모의폐액을 제조하여 과산화수소 주입량에 따른 세제 제거율, pH 변화에 따른 세제 제거율, 공기 공급량에 따른 세제 제거율을 도출하였다. 실험결과로서 과산화수소 주입량은 1000ppm, pH는 9.5일 때 최적 분해율을 보였고 공기 공급량의 영향은 받지 않는 것으로 밝혀졌다. 광분해 특성 규명을 위한 회분식 광분해 실험 결과, 광분해 반응 차수는 2차 반응임을 알 수 있었다. To apply the UV-photo oxidation process for the removal of detergent contained in the radwaste generated from the NPP, the effectiveness and feasibility were studied through the fundamental experiments. The simulants with TOC 50∼100ppm made of detergent were used for the lab-test. The optimum detergent removal rates due to the hydrogen peroxide volume, pH and air injection volume were investigated. The detergent removal rate was optimum at 1000ppm of hydrogen peroxide volume and at pH 9.5, while the air injection volume was not that much effective. The experimental result showed that the photo-oxidation degradation under the batch mode was of the second reaction.

      • PromethazineㆍHCI 複合內用水劑의 安定性에 관한 硏究

        徐成勳,鄭址昌 中央醫學社 1971 中央醫學 Vol.21 No.6

        This experiment is the variation of promethazine hydrochloride mixtures according to the promehtazine hydrochloride concentration. It is measured every hours under sun-light and every day at 30°C. The result were as follows. 1) It is results that the high concentrated promethazine hydrochloride is unstable and low concetrated one relatively stable compared with the high concentrated promethazine hydrochloride at 30°C. 2) According to the variations by sun-light it is concluded after one hour the variant rate of high concentrated promethazine hydrochloride is severe and low concentrated one relatively slight and from that time the variant rate was constant. According to the above results, it would be considered that promethazine hydrochloride mixtures is relatively stable in diluted solution and unstable in high concentrated solution.

      • KCI등재후보

        양식장 배출물 발효물의 어류 사료 첨가에 따른 넙치, Paralichthys olivaceus의 혈액학적 변동에 미치는 영향

        강주찬,지정훈,송승엽,문상욱,강지웅,이영돈,김세재 한국어병학회 2004 한국어병학회지 Vol.17 No.1

        본 연구는 우리나라 주요 양식어류인 넙치, Paralichthys olivaceus를 대상으로 육상수조식양식장 배출물 발효물의 어류 사료 첨가에 따른 혈액학적 변동에 미치는 영향을 검토하였다. 젖산균 및 효모를 사용하여 발효한 양식장 배출물의 이화학적 분석을 실시하였고, 발효물을 0.1, 0.5, 1.0 및 5.0% 농도로 8주간 투여하였다. 투여 4주째 및 8주째에 각 투여 구간별로 혈액학적 항목을 중심으로 그 차이를 확인하였다. 배출물 발효농도별 유의한 차이는 나타나지 않았지만, 분석시기에 따른 적혈구수, 혈색소 농도 및 혈색소 지수가 증가하는 경향을 나타내었으나, 주요 혈청 무기 및 유기성분은 배출 발효물 농도별로 유의한 차이는 나타나지 않았다. 또한 혈청 효소학적 조사에서는 조사시기별로 변동은 나타났지만, 동일 조시시기에서 각 구간별 유의한 차이는 나타나지 않았다. 따라서 이러한 육상 약식장 유래의 배출물 발효산물에 대한 다양한 방면의 연구가 진행되어야겠다. Effects of oral administration with fermented product from sewage in land-based seawater fish farm on haematological disturbance in the olive flounder, Paralichthys olivaceus was investigated. After 4 weeks of conditioning with a basal diet, fish were divided into 4 groups and provided experimental diet (0.1,0.5, 1.0 and 2.0%) supplement of fermented sewage for 80 days. Proximal analysis was performed for the product of sewage which was fermented by lactic acid and yeast. RBC count, hemoglobin concentration and hematocrit value were increased according to the treated periods, however, no statistical difference was observed between control and treatment groups. There were no significant difference in serum organic, inorganic compounds and enzyme activities between control and treatment groups. This study hypothesized that the supplement of fermented product from sewage in land-based seawater fish farm might be an additive sup plement for source of fish diet in view of haematological examination. Recycling of the sewage may be an economic artificial sources of diet for fish aquaculture practices.

      • 넙치, Paralichthys olivaceus 치어의 생존, 성장 및 산소소비에 미치는 수은의 만성적 독성

        강주찬,황운기,지정훈,김성길,김재원 한국어병학회 2002 한국어병학회지 Vol.15 No.1

        산업활동의 증가로 인해 해양에 유입되는 수은 (Hg)이 저서성 연안정착 어류인 넙치, Paralichthys olivaceus 치어의 생존, 성장, 사료효율 및 산소소비에 미치는 영향을 조사하였다. 6주 동안 0~0.13mg/L의 아치사 농도에서 넙치를 사육하며 Hg 독성에 대한 영향을 조사하였다. Hg 농도와 노출기간이 증가할수록 생존육은 감소했으며 6주 후, 0.05mg/L 이상의 농도 구에서 생존율이 급격히 감소했다. 성장률과 사료효율 또한, 각각 0.028mg/L (P<0.01)와 0.05mg/L (P<0.01) 이상의 농도 구에서 현저하게 감소하였다. 산소소비율은 0.05mg/L와 0.13mg/L의 농도구에서 각각 대조 구에 비해 25(P<0.01)와 32% (P<0.01) 감소해, 유의적인 차이를 나타내었다. 이상의 결과로부터 Hg 독성은 넙치의 성장, 사료효율 및 산소소비와 같은 생리적 기능을 저해해 생존율을 감소시키는 것으로 나타났다. Effect of mercury (Hg) toxicity on survival, growth, feed efficiency and oxygen consumption were examined in the juvenile olive flounder. Paralichthys olivaceus. Fishes were exposed to sublethal concentrations of Hg ranging from 0 to 0.13mg/L for 6 weeks. Hg reduced survival rate in a concentration and exposure period-dependent way and suddenly reduction occurred at Hg concentrations greater than 0.05mg/L after 6 weeks. Growth rate and feed efficiency also significantly decreased at greater than 0.028 and 0.05 mg/L respectively. Oxygen consumption rate was significantly decreased to 25 and 32% than that of the control at the Hg concentration of 0.05 and 0.13 mg/L respectively. These results suggest that Hg toxicity inhibit physiological function including growth, feed efficiency and oxygen consumption in the juvenile olive flounder, resulting in survival failure at high concentration.

      • TBT의 노출에 따른 넙치, Paralichthys olivaceus의 생존, 성장 및 산소소비의 변화

        강주찬,황운기,지정훈 한국환경독성학회 2002 환경독성보건학회지 Vol.17 No.3

        This study was carried out to examine the effects of his (tribytyltin)oxide (TBT), endocrine disrupting compounds (EDCs), on the changes of survival, growth and oxygen consumption rate in the oliver flounder, Paralichthys olivaceus. Oliver Flounders were exposed to sublethal concentration of TBT (0, 1.67, 3.20, 6.30 and 12.50㎍/L) during 6 weeks. Survival rate was decreased in a concentration and exposure period-dependent way and suddenly the reduction of more than 20% occurred at TBT concentration greater than 3.20㎍/L after exposure 6 weeks. Growth rate and feed efficiency significantly decreased at concentration greater than 3.20㎍/L. Oxygen consumption rate was also decreased in a concentration-dependent way and significantly decreased to 17, 48 and 67% than that of the control at the TBT concentration of 3.20, 6.32 and 12.50㎍/L, respectively. This study revealed that high TBT concentration (≥ 3.20㎍/L) reduced growth and oxygen consumption rates of the juvenile oliver flounder suggesting potential influence on the natural mortality of Paralichthys olivaceus in the coastal areas.

      • KCI등재후보

        범게, Orithyia sinica 유생의 생존과 성장에 미치는 암모니아와 아질산의 영향

        구자근,김종만,장차환,지정훈,강주찬 한국어병학회 2004 한국어병학회지 Vol.17 No.1

        범게, Orithyia sinica 유생을 대상으로 암모니아와 아질산에 대한 생존 및 성장에 관한 실험을 실시하였다. 암모니아 노출 실험구에서 zoea기 유생은 노출 20일후, 대조구가 80%의 생존율을 나타내었지만 10㎎/L 이상의 실험구에서는 37-45%의 생존율을 나타내었고, megalopa기 유생에서도 유사한 경향을 나타내었다. 암모니아가 범게 유생의 성장에 미치는 영향을 조사한 결과, zoea기 유생은 20㎎/L 이상의 농도에서 megaloparl 유생은 50㎎/L 이상의 농도에서 유의한 차이를 나타내었다. (P<0.05). 아질산 노출 실험에서는 zoea기 유생과 meglaopa기 유생에서 농도와 노출기간에 비례하여 생존율이 감소하였으며, 특히 150㎎/L 이상의 아질산 농도에 노출된 zoea기 유생가 megalopa기 유생은 대조구와 비교하여 유의한 성장 지연을 나타내었다(P<0.05). This study investigates the influence of waterborne ammonia and nitrite on the zoea and megalopa stage larvae of tiger crab, Orithyiu sinicu under laboratory condition, focusing on the effects on survival and growth as deleterious responses of toxicant. Survival rate of zoea stage larvae exposed to control levels, and to 5, 10,20 and 50 ㎎/L total ammonia-N, using a continuous flow system for 20 days was 80, 77, 45, 40 and 37%, respectively. Growth rate of zoea stage larvae exposed to 20 and 50 ㎎/L total ammonia was significantly lower than in controls after 20 days (P< 0.05). Survival rate and growth rate of megalopa stage larvae exposed to ammonia also decreased at greater than 10 and 50 ㎎/L, respectively. In the nitrite exposure experiment with zoea and megalopa stage larvae of tiger crab, survival rate was decreased in a concentration and exposure period-dependent way. The growth rate of zoea and megalopa stage larvae of tiger crab exposed to nitrite decreased at greater than 150 ㎎/L nitrite concentration.

      • Design Methodology of Bidirectional CLLC Resonant Converter for High-Frequency Isolation of DC Distribution Systems

        Jung, Jee-Hoon,Kim, Ho-Sung,Ryu, Myung-Hyo,Baek, Ju-Won IEEE 2013 IEEE TRANSACTIONS ON POWER ELECTRONICS - Vol.28 No.4

        <P>A bidirectional full-bridge CLLC resonant converter using a new symmetric LLC-type resonant network is proposed for a low-voltage direct current power distribution system. This converter can operate under high power conversion efficiency because the symmetric LLC resonant network has zero-voltage switching capability for primary power switches and soft commutation capability for output rectifiers. In addition, the proposed topology does not require any snubber circuits to reduce the voltage stress of the switching devices because the switch voltage of the primary and secondary power stage is confined by the input and output voltage, respectively. In addition, the power conversion efficiency of any directions is exactly same as each other. Using digital control schemes, a 5-kW prototype converter designed for a high-frequency galvanic isolation of 380-V dc buses was developed with a commercial digital signal processor. Intelligent digital control algorithms are also proposed to regulate output voltage and to control bidirectional power conversions. Using the prototype converter, experimental results were obtained to verify the performance of the proposed topology and control algorithms. The converter could softly change the power flow directions and its maximum power conversion efficiency was 97.8% during the bidirectional operation.</P>

      • KCI등재

        Pentachlorophenol impact assessment of haematological parameters in olive flounder, Paralichthys olivaceus

        Jee, Jung-Hoon,Min, Eun-Young,Park, Hee-Ju,Lee, Ok-Hyun,Keum, Yoo-Hwa,Kim, Su-Mi,Woo, Sung-Ho,Park, Soo-Il,Kang, Ju-Chan The Korean Society of Fish Pathology 2005 한국어병학회지 Vol.18 No.1

        The toxic effects of pentachlorophenol (PCP) on haematological parameters in olive flounder (Paralichthys olivaceus) after chronic exposure to dietary PCP (0.1, 0.5 and 1.0 mg/kg diet) for 2, 4 and 6 weeks were studied. A significant decrease in total RBC count, haemoglobin concentration and hematocrit value was noted in fish exposed to PCP compared to the non-exposed fish. The PCP treatment group showed significantly lower concentration of serum total protein and albumin, and significantly higher serum chloride, magnesium and total bilirubin levels compared with those in the control group. However, PCP had no major effects on serum glucose, total cholesterol, phosphate and calcium ions in flounder. These results demonstrated that PCP have induced adverse haematological impacts in the olive flounder, Paralichthys olivaceus. Because we found damages in blood-forming function and disruption in blood homeostasis due to chronic exposure to PCP, it is needed to develop further experimental studies for the risk assessment of this environmental pollutant.

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