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항정신병약물을 처음으로 사용하는 초발 정신증 환자에서 나타나는 체중 및 대사성 지표의 변화 : 후향적 연구
김우진,심주철,공보금,강제욱,문정준,김정은,김민걸,박민경,김성진,김현정,정도운 대한생물치료정신의학회 2011 생물치료정신의학 Vol.17 No.2
Objectives:This study was to identify weight & metabolic changes in first-episode psychotic patients with antipsychotics use and investigate the differences of weight & metabolic changes between first-episode psychotic patients and controls with antipsychotics use. Method:In this retrospective study, twenty eight first-episode psychotic patients and twenty eight controls with schizophrenia, schizoaffective or bipolar disorder defined by DSM-IV criteria were included. Information about demographic and clinical characteristics of the subjects was gathered from the medical records. Also body weight, sBP, dBP, fasting glucose, lipid profile and WBC count were evaluated before and after antipsychotics use. Rogistic regression was conducted to assess factors associated with weight gain. Results:First-episode psychotic patients showed more weight and BMI changes than controls after antipsychotics use, and these changes continue over 12 months. On the other hand, there were no significant factors associated with weight gain. Conclusion:The results of present study suggest that antispychotics is one of the major causes inducing weight gain of psychotic patients and antipsychotics-induced weight gain is more vulnerable to drug-naive first-episode psychotic patients.
공제욱 ( Je Wook Kong ) 한국사회사학회 2005 사회와 역사 Vol.0 No.67
One of the ways that the ideological orientation of the state can be implemented is through the regulation of clothing. Furthermore, clothes can also be a form of resistance and a means by which political dissension can be expressed. Imperial Japan``s regulation of clothing during the Colonial Period reveals precisely its ideological orientation. It begins with the suppression of baekeui(white robes) and the promotion of saekeui(dyed clothes) and continues with the enforcement of kukminbok(national suit) and momppe(women``s slacks). White robes worn by Koreans dirtied quickly and, due to the need for frequent washing, were suppressed during Japanese rule on the pretext of being uneconomical. With the advent of the 1930s, the Saenghwal gaesun undong ("movement for the improvement of living conditions") becomes the link through which the suppression of white robes materializes. The white robes of those who wore them were strewn with ink and red watercolor, and they were also stamped with large, square-shaped markings, this act explained as the implementation of dyed clothing. People who wore white robes in spite of this were prohibited from entering governmental and public offices as well as required to pay fines when caught. From the officially stated standpoint of economic efficiency, the suppression of the white robe may have attained its purpose, but it can also be interpreted as having an ulterior motive. That is, the primary factor in the suppression of white robes was the desire to construct an ideological ideal of the "modern man" and the "modern national citizen" by shattering longstanding traditions and lifestyles. With the shift into wartime footing upon the breakout of the Sino-Japanese War, every nook and cranny of Koreans`` daily live were regulated. In this way, as one manifestation of an apparatus designed to regulate society from deep within its veins, the national suit(kukminbok) made their appearance. It appears that only public service personnel were required to wear them at first, then all governmental officials and the like, and finally they were widely diffused through rank and file regulatory organizations. However, since the state clothes were basically contemporary business wear, from the standpoint of colonial Korea they were the clothing of the elite. Imperial Japan affixed the term "national citizen" to the national suit but the latter were men``s garments. For women, slacks worn by modern Japanese women were promoted instead. These slacks were first introduced to Colonial Korea mainly as emergency clothes worn for air defense exercises. But these slacks were spread and popularized so rapidly that eventually even peasant women, not to mention the middle class, came to wear them on a wide scale. Various apparatuses were devised in order to create the "loyal citizen," and the enforcement of both the national suit and women``s slacks-"national clothes for women"-can be viewed as one such apparatus. However, imperial Japan``s aim to confine Koreans within the framework of the "national citizen" did not entirely work according to its aim, and there was always a point of fissure where reality and the intentions of the state were at odds with each other.
이공선(Kong-Seon Lee),이은정(Eun-Jung Lee),조영욱(Young-Wook Cho),성명제(Myung-Je Seong),손영성(Young-Sung Son) 한국정보과학회 1997 한국정보과학회 학술발표논문집 Vol.24 No.2Ⅳ
소프트웨어는 분산환경, 객체지향 언어, 그래픽 사용자 인터페이스의 사용으로 인하여 점점 더 복잡해지고, 이에 따라 품질보증은 주요한 관심사가 되고 있으며, 이 분야에 대한 많은 연구가 진행중이다. 그리고, 최근 몇 년사이에 많은 테스트 도구의 기능은 향상되었고, 이들 도구의 도입 또한 활발해지고 있다. 본 논문에서는 지금까지 제안된 여러 가지 테스트 방법과 도구를 사용하여 분산환경에서 어플리케이션을 디버깅하는 분산처리 진단/교정 시스템 개발에 필요한 테스트를 수행하였다. 시스템 개발시 수행한 테스트에 대하여 기술하고 문제점에 대하여 알아본다.
성명제(Myung-Je Seong),이은정(Eunjung Lee),조영욱(Young-Wook Cho),이공선(Kong-Seon Lee),박창순(Chang-Soon Park) 한국정보과학회 1998 정보과학회 컴퓨팅의 실제 논문지 Vol.4 No.4
이기종 환경에서 개발되는 클라이언트 서버 응용프로그램의 디버깅은 개발환경의 이질성과 분산디버깅에 내재하는 복잡성으로 인하여 개발의 주요한 장벽이 되고 있다. 이러한 문제를 해결하기 위하여 본 연구에서는 클라이언트 서버 모델의 분산처리 디버거인 유니뷰 시스템을 개발하였다. 유니뷰 시스템 클라이언트는 이기종 호스트의 각 디버거들에 대한 단일화된 디버깅 개념과 인터페이스를 제공한다. 유니뷰 시스템 서버는 동일 호스트에 존재하는 한 개 이상의 디버거 프로세스와 연동함으로써 디버깅 서비스를 제공하며 개방성과 확장성을 갖는다. 본 시스템의 개발에서는 다양한 인터페이스의 단일화를 위해 디버깅 객체의 개념을 소개하였다. 디버깅 객체는 이질적인 디버거들의 디버깅 정보와 기능을 추상화하여 모델링한 것으로 본 시스템의 설계 기반을 제공하였다. Debugging client/server applications under heterogeneous development environment is a major bottleneck in the development process due to the heterogeneity and the complexity inherent to the distributed debugging nature. To solve these problems, a distributed debugger of client/server model named UniVIEW has been developed in this project. The UniVIEW client provides unified debugging concept and graphical user interface over various debuggers running on heterogeneous platforms. The UniVIEW server has open architecture which allows extensibility and scalability as well as debugging services by connecting more than one debugger processes residing on the same host. In the design of UniVIEW, a concept of debugging objects has been introduced to unify user interfaces and debugging contexts of various debuggers. As a result of an abstraction process of debugging information and debugging functions of heterogeneous debuggers, debugging object model provides basis of development of UniVIEW.
성명제(Myung-Je Seong),이은정(Eun-Jung Lee),조영욱(Young-Wook Cho),이공선(Kong-Seon Lee),박창순(Chang-soon Park) 한국정보과학회 1997 한국정보과학회 학술발표논문집 Vol.24 No.1A
분산처리 진단/교정 시스템은 이기종 분산환경에서 작동하는 어플리케이션을 진단/교정하는 도구이다. 본 논문에서는 “분산처리 진단/교정 시스템의 개발에 관한 연구”의 수행 현황과 연구 결과를 개요한다. 그리고 본 시스템을 분산처리 진단/교정 기능을 중심으로 살펴보고, 시스템의 구성 개요를 통해 개발 과정에서 고려된 원칙과 결정사항들을 소개한다. 또한 본 과제의 이후 연구방향을 살펴본다.
Kim, Hyunchul,Kong, Taeyoung,Chung, Sung Phil,Hong, Jung Hwa,Lee, Jong Wook,Joo, Youngseon,Ko, Dong Ryul,You, Je Sung,Park, Incheol Ovid Technologies (Wolters Kluwer) - Lippincott Wi 2017 Shock Vol.47 No.3
<P>Purpose:Recent technological advances have led to analyses of the delta neutrophil index (DNI), which reflects the fraction of circulating immature granulocytes, using specific automated blood cell analyzers. We evaluated the significance of the DNI as a prognostic marker for early severity in patients with acute cholangitis.Methods:We retrospectively analyzed patients initially diagnosed with acute cholangitis at emergency department admission, followed by diagnostic confirmation, during a set period. The DNI was determined on each day of hospitalization. Clinical outcomes were the incidence of shock requiring vasopressor/inotrope and 28-day mortality.Results:We included 461 patients who met our inclusion criteria. According to multivariate Cox proportional hazard models, higher DNI at admission (hazard ratio [HR]: 1.102; 95% confidence interval [CI]: 1.053-1.153; P<0.001), day 1 (HR: 1.069; 95% CI: 1.018-1.122; P=0.008), and day 2 (HR: 1.118; 95% CI: 1.053-1.186; P<0.001) were significant risk factors for 28-day mortality. Among patients with acute cholangitis, a DNI>4.9% at admission (HR: 5.632; 95% CI: 1.977-16.045; P=0.001) and day 1 (HR, 9.973; 95% CI: 2.666-37.302; P<0.001) and higher DNI (>2.5%) on day 2 (HR, 16.942; 95% CI: 2.15-133.496; P=0.007) were associated with increased 28-day mortality.Conclusion:Higher DNI levels are predictive markers of hemodynamic instability and 28-day mortality in patients with acute cholangitis. The accuracy of DNI for predicting hemodynamic instability and 28-day mortality is superior to that of other parameters.</P>