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RISS 인기검색어
- 검색키워드
- 저자 : Jang Jun-Bock (검색결과 256 건)
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金恩基,張峻福,李京燮,宋炳基 慶熙大學校 1995 論文集 Vol.24 No.-
This experiment was performed on analgesic, anti-pyretic, sedative, anti-swelling, anti-thrombotic, anti-tumor effect and response of isolated uterus by administrating high and low concentration of Sopokchukeotang's hot-water-extract to experimental animals. This administration purpose to investigate the efficacy of the Sopokchukeotang which is known as having effects on treating female genital diseases on basis of oriental medicine literature and its clinical use. The results obtained were as follows: 1. The writhing syndrome induced by acetic acid was decreased by administration of the Sopokchukeotang's hot-water-extract. However, there was no statistical significance between sample and control group. 2. The administration of the Sopokchukeotang's hot-water-extract elevated the pain threshold significantly by on hindpaw edema induced by 1% carrageenin in rat. 3. Abnormally elevated body temperature induced by thyphoid vaccine was decreased by the administration of the Sopokchukeotang's hot-water-extract. But, there was no statistical significance. 4. Sleeping time induced by Pentobarbital-sodium was prolonged by the administration of the Sopokchukeotang's hot-water-extract. However significant effect was recognized only in the treated by low concentration group(p<0.05). 5. The significant decrease of swelling induced by carrageenin was noted in the group treated by high concentration(p<0.05, p<0.01). 6. The group treated by low concentration showed significant anti-swelling effect on the swellings induced by yeast, but not in the group treated by high concentration didn't show it(p<0.05). 7. The serum FDP was decreased significantly by administrating the Sopokchukeotang's hot-water-extract to the experimental thrombosis(p<0.05, p<0.01). 8. The serum fibrinogen was increased significant by the administration of the Sopokchukeotang's hot-water-extract on the experimental thrombosis(p<0.01, p<0.001). 9. The prothrombin time was not influenced by the adminstration of the Sopokchukeotang's hot-water-extract on the experimental thrombosis. 10. The administration of the Sopokchukeotang's hot-water-extract did riot make a prolongation the survival in Saroma 180 ascitic tumor implanted Rats. 11. The administration of the Sopokchukeotang's hot-water-extract had no effect on the normal movement of the isolated uterus. However, it showed the relaxation effect on the oxytocin induced muscle contraction of the isolated uterus. According to the above results, it might be recognized that the Sopokchukeotang's hot-water-extract has the effect of analgesia, anti-pyrexia, sedation, anti-swelling, anti-thrombosis and relaxation effect on the oxytocin induced contraction of uterus muscle. However, anti-tumor effect of Sopokchukeotang's hot-water-extract was not appeared in the experiments. According to the above results. Sopokchukeotang's not-water-extract can be applied on the various inflammatory diseases in female genital organs.
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한방처방구성원리의 과학적 해석연구(Ⅱ) : 상한론 처방의 통계적 분석연구 Statistical Analysis of Sang-Han Prescriptions
김남재,김동현,장준복,송병기 慶熙大學校 1997 論文集 Vol.26 No.-
This study was made to objectify the principle of oriental medical prescriptions so that we could obtain the principle and the formulation of them. For that purpose, we analysed the formula and rule of 113 prescriptions recorded in 「ShanghanLun」, which have a few of components, and re widely used in clinical from ancient times to these days. At first we classified those prescriptions by their effect. Then we re-classified the herbs of the effect groups into four natures(cold, hot, warm and cool) and five kinds of flavors(wour, bitter, sweet, acrid and salty). And we classified the herbs into three grades -superior, medium, and inferior which were used in Shen Nong's Herbal Classic. By these means, we statistically evaluated the prescriptions recorded in 「ShanghanLun」based on the Four Regular Components(Monarch, Minister, Assistance and Laborer) According to the frequecy of the herbs used on the 108 prescriptions recorded in 「ShanghanLun」there are many concidences with the herbs used in these days. According to the effects, formulation of prescriptions and the effects have very colse relationship, and it might be related with the diseases on those days. The formulation of the prescriptions was carefully made by the for natures and five kinds of flavors. On the study of the three grades of Shen Nong's Herbal classic the superior and medium herbs mostly used, and the inferior herbs were very seldom used.
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한약이 임신중 태아에 미치는 영향(III) : 한약 및 한약 처방이 돌연변이원성과 염색체이상에 미치는 효과
김동현,이영경,김남재,장존복,송병기 경희대학교 동서의학연구소 2000 東西醫學硏究所 論文集 Vol.2000 No.-
Oriental herbal medicines were examined for mutagenicity in the reverse mutation test on Salmonella typimurium TA98/00 and chromosomal aberration test on cultured mammalina cells (Chinese hamster cell lines). The reverse mutation test was performed by a plate incorporation method with or without a metabolic activation system (S9 mix). Antaeeum, Aurantii Fructus and Kyoaekungkuetang significantly increased revertivle colonies on Salmonella typimurium TA 98 under the condition without S9 mix. Bojungikkitang significantly increased revertible colonies on Salmonella typimurium TA 100 under the condition with S9 mix than under the condition without S9 mix. The other tested herbal medicines did not significantly increased revertible colonies on any of the test strains under the condition with or without S9 mix. In the chromosomal aberration test. most tested herbal medicines did not significantly increased the number of aberrant cells under the conditions with S9 mix at concentrations of 1mg/ml, compared with the vehicle control. However, Gelatinum, Artemisiae Asiaticae Herba and Antaegumchultang, Kungsosan slightly increased revertivle colonies on any of the test strains under the conditions with S9 mix than under condition without S9 mix. These results indicate that most herbal medicines might be carefully used in obstetrics and gynecology, although they do not have the potent mutagenic potential under the present test conditions.
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Jang, Jun-Bock,Yoon, Young-Jin,Park, Jung-Hyun,Jeong, Haeng-Gyu,Cho, Jung-Hoon,Ko, Seung-Gyu,Lee, Chang-Hoon,Lee, Jin-Moo,Lee, Kyung-Sub Elsevier 2009 COMPLEMENTARY THERAPIES IN MEDICINE Vol.17 No.3
<P><B>Summary</B></P><P><B>Objective</B></P><P>This clinical study was conducted to investigate the efficacy and safety of an oriental herbal medicine native to Korea, <I>Chiljehyangbuhwan</I>, in treating primary dysmenorrhea.</P><P><B>Design and setting</B></P><P>A total of 100 primary dysmenorrhea patients who visited Kyung Hee University Korean Oriental Medicine Hospital between July 19 2004 and August 27 2004 were recruited. Secondary or drug-related dysmenorrhea was screened out through interviews and examination. The patients were grouped by fixed blocked randomization and administered either <I>Chiljehyangbuhwan</I> or placebo for one menstrual period in a double blind model. Visual Analogue Scale (VAS), Verbal Rating Scale (VRS), and Multidimensional Verbal Rating Scale (MVRS) were used to evaluate dysmenorrhea severity. A total of 71 patients who passed the screening test and remained to the last were divided into either placebo or <I>Chiljehyangbuhwan</I> group, and each were further split into smaller subsets (indication, non-indication, and unspecified group) according to Korean Oriental medical diagnosis.</P><P><B>Results</B></P><P>In the non-indication group, the placebo and <I>Chiljehyangbuhwan</I> group did not show significant difference in VAS, VRS, and MVRS scores before medication (1st VAS, 1st VRS, 1st MVRS), after medication (2nd VAS, 2nd VRS, 2nd MVRS), and in changes in scores before and after (ΔVAS, ΔVRS, ΔMVRS). In the indication group, the placebo and <I>Chiljehyangbuhwan</I> group showed significant difference in change in VAS and MVRS scores (ΔVAS and ΔMVRS). No evidence of toxicity could be found, and no serious adverse reactions to <I>Chiljehyangbuhwan</I> were reported.</P><P><B>Conclusion</B></P><P>The results suggest that <I>Chiljehyangbuhwan</I> is effective and safe in treating primary dysmenorrhea when prescribed appropriately under Korean Oriental medical diagnosis.</P>
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Measurement of Rn-222 Gas Concentration of Newly Constructed Apartment House in Gwangju Gwangsan-Gu
Hee jun Jang,Sang bock Lee 한국방사선학회 2015 한국방사선학회 논문지 Vol.9 No.4
라돈은 우라늄-238과 토륨-232가 방사성붕괴 과정을 거친 후 생성되며, 무색, 무취의 불활성 기체로서 지하 또는 밀폐된 공간에 축적된다. 우라늄-238과 토륨-232는 지각의 암석이나 토양 등에 포함 돼 있다. 건축자재는 암석이나 토양을 재료로하여 만들어 진다. 가스 형태의 라돈은 호흡기를 통해 폐로 유입되고 라돈의 딸핵종이 폐나 기관지에 침적 되어 폐암을 일으키는 원인이 된다. 본 연구는 광주광역시 광산구에 위치한 신축 아파트를 대상으로 창문을 닫고 열은 상태에서 라돈 측정기를 이용하여 측정하였다. 측정 결과로 보아 신축 아파트 실내 평균 라돈농도는 미국 일반인 공기 중 라돈가스 최대허용농도 기준치 4 pCi보다 이하의 값이 나타난다는 것을 볼 수 있다. 측정 결과로 볼 때 신축 아파트의 라돈농도로 인한 피폭은 크지 않을 것으로 예상한다. 그러나 라돈가스가 신체 내에 축적이 되면 폐와 같은 경우는 폐암과 같은 피폭에 의한 피해를 얻을 수 있으므로 방사선 방어적 측면에서 측정 결과와 같이 라돈 농도를 낮추기 위해 창문을 자주 열어 환기를 시켜 피폭을 줄이는 것이 필요하다고 생각 된다. Radon is produced after the Uranium-238 and thorium-232 undergone radioactive decay process is a colorless, odorless inert gas is stored in a basement or an enclosed space. Building materials are made by a rock or soil materials. Form of radon gas is introduced into the lungs through the respiratory tract and deposited in the lungs or bronchial Daughter nuclides radon causes lung cancer. In this study, To subject the Constructed Apartment in Gwangju Gwangsan-Gu, the position is closed window and opened window was measured using a measuring instrument for radon. The measured results indicate that the measurement was carried out in concentrations of radon gas measured at Newly Constructed Apartment is low than United states in the radon concentration in air public 4 pCi called radon gas baseline maximum allowable concentrations. The exposure caused by radon concentration of new construction apartment when on the measurement results is expected to be insignificant. However, when radon gas like this is that it accumulates in the body and lungs get damaged due to exposure, such as lung cancer often open the windows to reduce the radon concentration measurements, such as in radiation protection aspects to the ventilation to reduce exposure it is considered necessary.
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Effects of Daeyoung-Jun on Sex Hormone Activity and Bone Metabolism in Ovariectomized Rats
Song, Byoung-key,Jang, Jun-bock INSTITUTE OF ORIENTAL MEDICINE KYUNG-HEE UNIVERSIT 1998 JOURNAL OF ORIENTAL MEDICINE Vol.3 No.1
This study was performed to investigate the effect of Daeyoung-Jun in oriental medicine on climacteric disturbance. The experimental model of menopause was induced by bilateral ovariectomy in rats. These were administered orally with liquid extract Daeyoung-Jun 1.6g/kg for 30 days before ovariectomy (Sample A group), for 30 days after ovariectomy(Sample B group) and after an additional 30 days of ovariectomy (Sample C group). The level of serum FSH, serum LH, serum estradiol, serum progesterone, total ash weight, calcium in the tibia, serum osteocalcin, serum alkaline phosphatase activity was measured. The differences in these levels were obtained at 40, 50 and 60 days after ovariectomy. From this study we could recognize that Daeyoung-Jun has the effect of controling the hypothalamus-pituitary gland-ovary axis, so it can improve sex hormone changes and the imbalance of bone metabolism. We came to find out that the most appropriate dosing time was athe Sample C group. Therefore we expect that this kind of oriental medical treatment can be used for osteoporosis.
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