RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      검색결과 좁혀 보기

      선택해제
      • 좁혀본 항목 보기순서

        • 원문유무
        • 음성지원유무
        • 원문제공처
          펼치기
        • 등재정보
          펼치기
        • 학술지명
          펼치기
        • 주제분류
          펼치기
        • 발행연도
          펼치기
        • 작성언어
        • 저자
          펼치기

      오늘 본 자료

      • 오늘 본 자료가 없습니다.
      더보기
      • 무료
      • 기관 내 무료
      • 유료
      • 서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

        김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

        In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

      • 페니실린 내성 폐렴구균 균혈증의 임상적 특성

        정두련,송재훈,김은옥,류지소,이남용,이혁,백경란,김성민,배직현,우준희,김양수 대한감염학회 1997 감염 Vol.29 No.4

        목적: 지역사회 획득 감염의 매우 흔한 원인균인 폐렴구균의 페니실린 및 다른 항균제에 대한 내성의 증가는 세계적으로 문제가 될 뿐 아니라 국내에서 더욱 큰 문제로 대두되고 있다. 본 연구는 항균제 내성 여부에 따른 폐렴구균 균혈증의 임상적 특성 및 위험 요인를 분석하여 항균제 내성의 임상적 의미를 조사하고자 시행되었다. 방법:1989년부터 1994년까지의 폐렴구균 균혈증 41례를 대상으로 하여 의무기록지를 조사하였다. 균주의 항균제 감수성 검사는 oxacillin 디스크 확산법으로 페니실린 내성 여부를 거사한 후, 한천 희석법을 이용하여 페니실린을 비롯한 11개의 항균제의 MIC (minimal inhibitory concentration)를 구하고 감수성 여부를 판정하였다. 결과: 41균주 중 68.3%가 페니실린에 대하여 내성(중등도 12.2%, 고도 56.1%)을 보였으며 다제내성률은 61%였다. 특히 소아에서는 100%(고도 88.2%)의 내성률을 보여 성인보다 내성률이 더 높았다. 페니실린 내성 균주는 대부분 다른 β-lactam 항균제에도 내성을 보였으며 특히 페니실린 고도 내성 균주는 cefotaxime, ceftriaxone에 대하여 100% 내성을 보였고 imipenem에 대해서도 95.5%의 중등도 내성률을 보였다. 혈청형은 19와 23이 많았고 그 외에 6이 있었다. 임상적 특성의 분석상 환자들의 연령분포는 3개월부터 82세까지였으며 기저질환을 가지고 있는 환자가 56%이었으며 지역사회 획득 감염이 71%였다. 균혈증의 일차감염원은 폐렴(22례, 54%)과 수막염(5례, 12%)이 가장 많았다. 페니실린 내성의 위험요인으로는 소아 연령만이 유의한 요인으로 분석되었다. 항균요법에 대한 반응을 볼 때 실패한 경우는 고도 내성 군의 20%에서만 있었으며 병원내 총사망률은 페니실린 감수성 군이 30%, 중등도 내성 군이 20%, 고도 내성 군이 13.6%로서 유의한 차이는 없었다. 결론: 페니실린 내성 폐렴구균은 국내에 만연하고 있으며 높은 다제내성률을 보였다. 이들은 대개 지역 사회 획득 감염을 일으키는데 균혈증의 경우 그 사망률은 내성 여부에 따른 차이를 보이지 않았다. 소아연령만이 페니실린 내성의 위험요인으로 분석되었다. Background: The emergence of penicillin-resistant Streptococcus pneumoniae (PRSP) poses serious therapeutic problem in clinical practice, especially in cases with bacteremia or meningitis. Methods: To investigate clinical characteristics of bacteremic pneumococcal diseases due to PRSP, we retrospectively analyzed 41 cases with cocumented bacteremic diseases seen in a tertiary care hospital between 1989 and 1994. Results: Agar dilution test of 41 strains isolated showed that 68.3% of S. pneumoniae were PRSP [high-level resistance(R) 56.1%, intermediate resistance(I) 12.2%]. High-level resistant strains were not susceptible to other β-lactam agents, whereas isolates of penicillin-susceptible S. pneumoniae(PSSP) were uniformly susceptible to all β-lactam agents. Predominant serogroups of PRSP were 19, 23, and 6. Bacteremic diseases caused by PRSP included pneumonia (22), meningitis (5), peritonitis (3), acute otitis media (2), acute tonsillitis (2), endocarditis (1), pyelonephritis(1), and primary bacteremia(5). Children were more likely to be infected with PRSP with high-level or intermediately resistant strains than were adults(P=0.0001), but no differences were seen between PRSP and PSSP regarding sex. previous antibiotic history, previous hospitalization, and underlying immunocompromised conditions. Most cases were community-acquired (R 78.3%, I 60%, S 61.5%). Fatality rates of patients infected with PRSP were not different significantly from PSSP (22.6% vs. 30%). However, most fatal cases had underlying immunocompromised conditions. Conclusion: PRSP is widely prevalent in Korea and shows resistance to most antibiotics. It causes community-acquired bacteremic diseases with poor outcomes, but there was no difference in mortality between patients infected with PRSP and PSSP. Pediatric age was the only risk factor for penicillin resistance.

      • Murine Sarcoma Virus로 변이시킨 가토신장세포의 지질조성에 대한 연구

        정주광,박주홍,김우제,김경진,고광삼 朝鮮大學校 附設 醫學硏究所 1986 The Medical Journal of Chosun University Vol.11 No.1

        Differencies of lipid composition of mnrine sarcoma virus 970-17 traiisfomed rabbit kidney cells and their plasma membranes were studied. Free cholesterol was the major neutral lipid extracted from the whole cells and plasma membranes of all these cells. The micromoles of total neutral lipids and phospholipids are elevated in plasma membranes compared to whole cells from monolayer cultures. The distribution of fatty acids in the major lipid classes of plasma membranes and whole cells generally follow the composition of calf serum used in the culture media.

      • 磁束 制御型 PWM INVERTER에 의한 誘導 電動機의 可變速 制御

        禹靖仁,文在星 동아대학교 공과대학 부설 한국자원개발연구소 1987 硏究報告 Vol.11 No.1

        This paper attempts driving for minimized riffle torque of three phase Induction motor with optimized switching pattern of Pulsewidth-modulated Inverter by a microcomputer, this pattern is obtained by a new founded 1-m axis on the vector of instantaneous linkage flux locus and dispersive constant of riffle torque that is made from harmonic output currents of PWM Inverter. In this paper, Althogh the actual linkage flux locus is demanded high frequency switching for obeying a ideal limkage flux locus in the PWM Inverter, we find out smoothed variable-speed controlling by the optimized switching pattern on the software of microcomputer(Z-80).

      • KCI등재
      • 소아과 입원 환자에 대한 통계적 고찰

        정용현,서우식,유재홍,변상현 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2

        For the purpose of assessing the disease patterns by the body organ system in patients of the pediatric age, we performed a statistical analysis of diseases of patients admitted to the department of pediatrics at Chungnam National University Hospital from January 1990 to December 1994. The results obtained were as follows : 1. Total numbers of in-patients were 8,007, of which 4,923 were male and 3,084 were female. The ratio male to female was 1.60 : 1. 2. Prevalence of the diseases classified by body organ system was in the following order : neonatal diseases (34.6%), respiratory diseases (17.4%), infectious diseases (11.5%), congenital anomalies (5.5%), digestive diseases (5.1%), genitourinary diseases (4.9%), neoplasm (4.7%), blood diseases (3.3%), nervous system diseases (2.8%), metabolic and endocrine diseases (2.4%), circulatory system diseases (2.3%), skin and subcutaneous diseases (1.3%), musculoskeletal and connective tissue diseases (1.2%), mental and behavior disorders (0.4%). 3. Major diseases in each body organ system were as follows : 1) infectious diseases : unspecified acute gastroenteritis (35.9%), viral meningitis (10.4%), Rotaviral enteritis (6.8%), sepsis (6.7%), measles (5.8%). 2) neoplasm ; ALL (34.1%), AML (15.8%), Wilms tumor (12.8%), NHL (8.2%), neuroblastoma (5.6%) 3) blood diseases : allergic purpura (24.2%), aplastic anemia (17.1%), ITP (16.4%), iron deficiency anemia (15.8%). 4) metabolic and endocrine diseases : short stature (22.0%), hypocalcemia (13.8%), metabolic acidosis (9.6%), IDDM (6.4%). 5) mental and behavior diseases : neurosis (47.7%), mental retardation (18.2%). 6) Nervous and sensory system diseases : epilepsy (43.2%), cerebral palsy (12.1%), otitis media (9.3%), encephalopathy (6.2%). 7) circulatory system diseases: congestive heart failure (29.2%), dilated cardiomyopathy (8.0%), rheumatic fever (8.0%), mitral insufficiency (6.8%), hypertension (6.4%). 8) respiratory diseases : pneumonia (40.1%), URI (9.6%), acute tonsillitis (9.4%), asthma (8.5%), acute bronchiolitis (8.3%), croup (7.1%), acute bronchitis (4.1%). 9) digestive system diseases : unspecified hepatitis (22.8%), acute gastritis (13.8%). CAH (12.6%), intussusception (7.8%), constipation (7.1%). 10) skin and subcutaneous diseases : cellulitis (23.1%), lymphadenitis (19.7%), urticaria (15.6%), atopic dermatitis (8.8%), furuncle (8.2%). 11) musculoskeletal and connective tissue diseases : Kawasaki disease (76.8%), JRA (8.5%), SLE (7.0%). 12) genitourinary system diseases : UTI (29.0%), minimal change nephrotic syndrome (27.3%), APSGN (7.6%), APN (4.9%). 13) congenital or chromosomal abnormalities : VSD (38.7%), ASD (10.5%), TOF (8.4%), PDA (5.2%), CHPS (4.5%), Down syndrome (4.1%). 14) neonatal diseases : jaundice (32.0%), prematurity (12.7%), RDS (5.7%), sepsis (4.5%), birth asphyxia (3.0%), SGA (3.0%). 15) Others : febrile convulsion (45.6%), failure to thrive (9.2%), FUO (8.9%), drug intoxication (8.2%). 4. Common diseases for admission in pediatrics were in the following order : jaundice, pneumonia, unspecified acute gastroenteritis, VSD, RDS, URI, acute tonsillitis, acute lymphadenitis, ALL, sepsis, asthma, acute bronchiolitis, UTI.

      • 과학수업모형의 비교 분석 및 내용과 활동 유형에 따른 적정 과학수업모형의 고안

        정완호,권재술,최병순,정진우,김효남,허명 한국교원대학교 과학교육연구소 1996 청람과학교육연구논총 Vol.6 No.1

        The purpose of this study is to develop appropriate science teaching models which can be applied effectively to relevant situations. Five science teaching models; cognitive conflict teaching model, generative teaching model, learning cycle teaching model, hypothesis verification teaching model and discovery teaching model, were identified from the existing models. The teaching models were modified and in primary and secondary students using a nonequivalent pretest-posttest control group design. Major findings of this study were as follows: 1. For teaching science concepts, three teaching models were found more effective; cognitive conflict teaching model, generative teaching model and discovery teaching model. 2. For teaching inquiry skills, two teaching models were found more effective; learning cycle teaching model and hypothesis verification teaching model. 3. For teaching scientific attitudes, two teaching models were found more effective; learning cycle teaching model and discovery teaching model. Each teaching model requires specific learning environment. It is strongly suggested that teachers should select a suitable teaching model carefully after evaluating the learning environment including teacher and student variables, learning objectives and curricular materials.

      • KCI등재

        K 강선 및 긴장대 강선을 이용한 원위 쇄골 제 2형 골절의 치료

        정환용,이우석,전택수,김대환,김광균,임재우 대한골절학회 2003 대한골절학회지 Vol.16 No.2

        목 적: 쇄골 윈위부 제 Ⅱ형 골절의 치료에 있어 견봉 쇄골 관절을 통과하지 않고 직접 골편을 고정시키는 K 강선 및 긴장대 강선을 이용한 고정술로 치료한 환자에서 임상 결과를 후향적으로 분석하여 보고하고자 한다. 대상 및 방법: 2000년 5월부터 2001년 5월까지 쇄골 원위부 제 Ⅱ형 골절로 관혈적 정복술 및 K 강선 및 긴장대 강선을 이용한 고정술을 실시한 12례 중 최소 1년 이상 추시가 가능한 11례를 대상으로 하였다. 임상적 평가를 위해 최종 추시에서 변형된 견관절 기능 평가법을 사용하여 결과를 분석하였고 골유합 상태, 합병증, 견관절 운동범위를 측정하였다. 결 과: 전례에서 골유합을 얻었으며, 수술 후 골 유합까지의 기간은 평균 10주 (8~12주)였다. 최종 추시 상 견관절의 운동범위는 모두 정상 소견이었고, 변형된 견관절 기능 평가상 우수 9례, 양호 2례였다. 결 론: 쇄골 원위부 제 Ⅱ형 골절에서 K 강선 및 긴장대 강선을 이용한 고정술은 좋은 치료 방법 중 하나로 사료된다. Purpose: This is retrospective study to analyze the clinical results of the usefulness of K-wires and tension band wiring that fix the fracture fragment directly without passing the acromioclavicular joint in distal clacivle type Ⅱ fractures. Materials and Methods: From May 2000 to May 2001, eleven patients with distal clavicle type Ⅱ fracture were treated by open reduction and internal fixation with K-wires and tension band wiring. The clinical results were analyzed according to modified shoulder rating scale for distal clavicle freacture. Radiological union, complication, and range of motion of the shoulder were assessed. Results: All fractures were united at 10 weeks (8~12 weeks) in average. Finally, full range of motion of the shoulder joint was achieved in all patients. No complication was found and the modified shoulder rating scale for distal clavicle fracture were as follows: excellent 9 and good 2. Conclusion: K-wires and tension band wiring can be a good treatment method for distal clavicle type Ⅱ fractures.

      • KCI등재

        생체분자 분리 및 분석에 있어서의 마이크로-나노 시스템

        정우재,신동식,이윤식 한국공업화학회 2002 공업화학 Vol.13 No.8

        휴먼게놈 프로젝트가 종료됨에 따라, 우리 몸의 대사ㆍ생리 작용, 질병에 직접 관여하고 있는 단백질의 분리와 구조 분석에 관심이 집중되고 있다. 현재 프로테오믹스의 근간이 되고 있는 2D-젤 전기영동법은 긴 소요시간, 복잡한 과정, 재현성 문제, 검출한계 등 그 문제점이 지적되고 있으며, 이를 해결하기 위한 마이크로-나노 대체 기술들이 최근 속속 보고되고 있다. 이에 본 총설에서는 단백질을 포함한 생체분자의 분리ㆍ검출 및 미량 분석을 위한 마이크로-나노 시스템 기술들의 최신 연구동향을 알아보고자 한다. 구체적으로는 마이크로 비드 어세이를 기반으로 하는 마이크로 분석 시스템, 나노 테크놀로지를 이용한 바이오 센서 또는 바이오 칩 분야와 마이크로 어레이 기술 등과 그 응용을 중심으로 최근 2∼3년간 중요 논문에 보고된 내용을 소개함으로써 최근 발전하고 있는 마이크로-나노 기술의 중요성에 대해서 언급하고자 한다. In the post-genomic era, purification and structure identification of proteins that are related to cell functions and diseases became the most important research topics. Although 2D-gel electrophoresis is currently the most widely accepted technique for the separation of complex protein mixtures, it still possesses some drawbacks to overcome. Being very labor intensive, it is time consuming, difficult to obtain reproducible results, and has low detection limit. Recently, various methods that utilize micro/nano systems to separate and analyze biomolecules including proteins appeared to overcome these drawbacks. In this report, we overviewed recent research trends of micro/nano bio field, by reviewing recent papers for the last 2∼3 years, and emphasized the importance of the development of bead based micro analysis system, nanotechnology for biosensing, and protein micro array system.

      • 平肺湯이 Oleic acid로 誘發된 家犬의 急性 肺水腫에 미치는 영향

        鄭在雨,韓相桓 圓光大學校 韓醫學硏究所 1992 원광한의학 Vol.2 No.1

        Certain oriental medication have been shown to be effective in decreasing pulmonary vascular resistance and increasing cardiac output in primary pulmonary artery pressure secondary to pulmonary edema. So oleic acid was administered in 14 dogs in order to induce acute lung injury. And we studied the hemodynamecs and blood gas changes of Pyengpaetang(平肺湯) (50mg, 100mg) with continuous postive pressure was ventilation iv pulmonary edema. The pulmonary edema group, arterial oxygenation was improved after 5 and 10 cm H_2O PEEP (positive end expiratory pressure), but cardiovascular system was depressed. Blood pressure and cardiac output were decreased, and CVP, MPAP, PCWP were increased. In Pyengpaetang(50mg) group, mena aortic pressure was decreased and PCWP(pulmonary capillary wedge pressure)was decreased remarkably, while there was a significant increase in cardiac output. And there was improvement in PaO_2 and PaCO_2 without hemodynamic changes after applying 5 cm H_2O PEEP, but arterial blood gases (PaO_2, PaCO_2) were improved, while cardiovascular effects were depressed after 10cm H_2O PEEP. In Pyengpaetang (100mg) treated group, there was no significant hemodynamic change. But mena pulmonary arterial pressure was signifiacntly increased, and cardiac output was decreased signifiacntly after applying the more degree of PEEP. And blood gases were not changed significantly after applying the more degree of PEEP. The above results suggest that the effects of Pyengpaetang (50mg) group is superior to those of Pyengpaetang(100mg) group on the effects of himodynamics and gas exchanges in acute lung injury in dogs. So we can conclude that lower degree PEEP 5cm H_2O is more beneficial in Pyengpaetang (50mg) treated group.

      연관 검색어 추천

      이 검색어로 많이 본 자료

      활용도 높은 자료

      해외이동버튼