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      • 바터 팽대부에 생긴 유암종 1예

        강명주,지삼룡,박석주,이재익,조영완,김준영,박성재,박은택,이연재,이상혁,설상영,배상균 인제대학교 2006 仁濟醫學 Vol.27 No.-

        Carcinoid tumors have been reported in a wide range of organs but most commonly involve the lungs, bronchi and gastrointestinal tract. Within the gastrointestinal tract, appendix is the most common location for carcinoid, followed by the distal small intestine, the rectum, and the stomach. Among these, primary involvement of the ampulla of Vater is extremely rare. We report a case of carcinoid tumor of ampulla of Vater. A 62-year-old man presented with epigastric soreness. Gastroduodenal endoscopy showed hyperemic bulging mass on ampulla of Vater and diagnosed as carcinoid tumor by histologic finding, with immunohistochemical study. In ^(111)In-octreoscan, tumor had regional lymph node metastasis, but no evidence of distant metastasis. Pancreatoduodenectomy with lymph node dissection was performed.

      • KCI등재후보

        2003년 국내 중증급성호흡기증후군 진료 현황 및 문제점 분석

        이진수,김은실,정문현,백제중,정선화,안주희,최영화,이선희,고철우,김성범,김민자,박승철,기현균,송재훈,최상호,김양수,이상오,조용균,박영훈,정숙인,김연숙,이흥범,손창희,장성희,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3

        목적 : 2002년 말 중국에서 SARS가 발생한 이후 국내에서도 2003년 10월까지 총 3명의 추정환자, 17명의 의심환자가 보고되었다. 향후 추가적인 SARS의 유행이 우려되는 상황에서, 그간의 SARS 환자 진료에 있어서의 실질적인 준비사항, 진료 현황 등에 대한 조사를 통해 문제점을 파악하여, 향후 더 나은 대비가 될 수 있도록 개선점을 제시하고자 하였다. 재료 및 방법 : SARS로 의심되는 환자를 진료 경험이 있는 병원의료진을 대상으로 2003년 10월에 설문조사를 실시하였다. 설문에는 SARS 환자 진료 시의 실질적인 조치, 진료 현황, 병실, 응급실 및 외래에서의 격리 시설과 준비사항, 보건당국의 관리와 지원에 관한 사항을 포함하였다. 결과 : 대상이 되는 22개 병원 중 17개(17/22, 77.2%) 병원이 설문에 응하였다. SARS 환자를 위한 격리실은 응급실, 외래, 일반병실 및 중환자실에서 각각 9개(9/17, 52.9%), 5개(5/17, 29.4%), 15개(15/16, 93.7%), 4개(4/16, 25%) 병원에서 음압처리가 되어있지 않은 일인실 혹은 다인실이 사용되었고, 1개(1/16, 6.3%) 병원에서만 일반병실에서 음압격리실이 운영되었다. 입원환자의 진찰 시 개인보호구의 착용은 거의 모든 의료기관에서 이루어졌다. 보건당국에서 SARS지정병원의 시설 등을 사전에 확인한 곳은 1곳(1/12, 8.3%)이였고, 14개 병원(14/15, 93.3%)에서는 보건당국에 의뢰한 검사결과를 통하 받지 못하였다. 결론 : 의료기관에서 SARS 환자용 격리실뿐만 아니라 기존의 격리실 설비 등이 미흡하였으며, 특히 중환자실 및 외래의 준비가 더욱 부족하였다. 보건당국의 의료기관에 대한 종합적인 지원이 부족하였고, 병원과의 원활한 연계가 잘 이루어지지 않았다. SARS 만이 아닌 격리를 필요로 하는 질환의 적절한 진료를 위해 향후 병원 시설의 정비와 정부차원에서의 보다 구체적이고 실질적인 대책마련이 필요하다. Background : There was an worldwide outbreak of the Severe Acute Respiratory Syndrome (SARS) originated from China in late 2002. During that period three cases of suspected SARS and 17 cases of probable SARS were reported in Korea. With the concerns about the reemergence of SARS-coV transmission, it is important to be prepared for any possibility. So, this study is aimed to analysis the past measures in managing SARS and propose the amendatory plans to improve the preparedness. Materials & Methods : Questionnaires were collected among clinicians with any experience in managing the probable or suspected SARS cases in Oct. 2003. 17 out of 22 hospitals responded to the questionnaire. The contents in the questionnaire were practical activities, personal equipments, response plans, isolation facilities in emergency centers, outpatient clinics, general wards and intensive care units, and relationship with the public health department. Results : The dedicated isolation rooms in emergency centers, outpatient clinics, general wards, and intensive care units were prepared in 9 (9/17, 52.9%), 5 (5/17, 29.4%), 15 (15/16, 93.7%), and 4 (4/16, 25.0%) hospitals, respectively. Except for one hospital that newly made negative pressure room for SARS, single or multi-bed rooms without airborne infection control were used in all the other hospitals. The personal precaution principles were kept quite well in general wards. Before the designation of SARS hospital by the public health department prior evalution to see if the hospital was suitable for managing SARS was conducted in only 1 (1/12, 8.3%) hospital. The results of laboratory diagnosis were reported back in 1 (1/15, 6.6%) hospital. Conclusions : The isolation facilities which can control airborne infection were almost deficient not only for SARS but also for other respiratory transmissible diseases. For the infection control of transmissible diseases including SARS, more investment is needed on medical facilities and comprehensive support from the public health department required.

      • 아이스하키 선수들의 포지션별 슬관절 및 견관절의 등속성 근력에 관한 비교 연구

        박영균,전종국,이재문 경희대학교 체육과학연구소 2001 體育學論文集 Vol.29 No.-

        The purpose of this study was to compare the isokinetic muscular among ice-hockey athletics's positions(FW, DF, GK). For this purpose, the subjects were 29 athletes(FW 10, DF 10, GK 9), and the isokinetic strength were tested by knee and shoulderat. Knee tests processed at 5 times to 60˚/sec, 5 times to 120˚/sec, 20 times to 180˚/sec, and shoulder tests processed at 5 times to 60˚/sec, 90˚/sec, 120˚/sec with the CYBEX NORM system. The test items were peak torque, total work, average power, and H/Q ratio. The results of this study were as follows; 1. For both knee extension and flexion peak torque, showed DF, GK, FW order, and there was significant difference between DF and FW in extension, and between DF/GK and FW in flexion. 2. For both knee extension total work, showed DF, GK, FW order and there was significant difference between DF/GK and FW in extension And no significant difference among positions in flexion 3. For both knee extension and flexion average power, showed DF, GK, FW order, and there was significant difference between DF and FW. 4. For knee H/Q ratio, showed DF, GK, FW order, and there was no significant difference among positions 5. For both shoulder extension and flexion peak torque, showed DF. GK, FW order, and there was significant difference between DF and FW. 6. For both shoulder extension and flexion peak torque, showed DF, GK, FW order, and there was significant difference between DF and FW. 7. For both shoulder extension and flexion peak torque, showed DF, GK, FW order, and there was significant difference between DF and FW in flexion. But, no significant difference among positions in extension. 8. For shoulder H/Q ratio, showed DF, GK, FW order, and there was no significant difference among positions.

      • 오리 嗅粘膜의 組織學的 및 組織化學的 硏究

        朴在贊,金武剛,金弘善,申台均 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.1

        This paper dealt with the histological feature of the Pekin duck olfactory mucosa and the specificity of the types of mucopolysaccharides present in the secretory cells of the duck olfactory mucosa. The nasal parts of ducks (1-week-old and 10-week-old) were fixed with 10% neutral formalin, decalcified, embedded in paraffin. Serial sections were cut 5 um thick and stained with alcian blue(pH 2.5) to demonstrate acidic mucopolysaccharides and the periodic acid-Schiff reaction to identify neutral mucopolysaccharides. The results were summarized as follows. 1. The duck olfactory mucosa consisted of the olfactory epithelia which compose of the receptor neurons, supporting cells, basal cells and goblet cells, and the lamina propria which contained Bowman's glands, olfactory nerve bunbles and connective tissue cells. 2. The thickness of the olfactory mucosa was 121.5±25.67um in the 1-week-old ducks, and 202±45.82km in the 10-week-old ducks. Increased thickness of olfactory mucosa was due to the increased thickness of lamina propria. 3. Histochemical techniques of the olfactory mucosa in 10-week-old ducks demonstrated that Goblet cells, sppporting cells and Bowman's gland contained both neutral and acidic mucopolysacc harides, the neutral mucopolysaccharides staining became enhanced first in the Goblet cells and Bowman's gland, and then in supporting cells. In 1-week-old ducks, both acidic and neutral mucopolysaccharides of Goblet cells reacted strongly, but those of supporting cells and Bowman's gland reacted presumably.

      • KCI등재후보
      • 중학교 Ice-Hockey선수와 축구선수의 체력과 심폐기능에 관한 비교 연구

        박영균,문재형 경희대학교 체육과학연구소 1996 體育學論文集 Vol.24 No.-

        The purpose of this study was to investigate difference of the physical fitness and the cardiorespiratory function between some trained soccer and ice-hockey players. The subject are 15 persons. The results of this study are as fellow: 1)No significant difference appered in terms of the height between the 2 groups. In the weight and chest, there was a significant difference(p〈0.01) between the soccer and ice-hockey player. 2)No significant difference appered in terms of grip strength(right), leg strength extension between the 2 groups. In the grip strength(left), back strength, it showed that there was significant difference(p〈0.05) between ice-hockey player(30.93±7.44kg, 84,80± 17.82kg), and soccer player(26.03±4.86kg, 72.13±15.93kg). In the left and right arm strength flexion, it showed that there was a significant difference(p〈0.01) between ice-hockey player(25.40±6.99kg, 25.13±8.21kg) and soccer player(18.53±3.40kg, 18.13±2.59kg). 3)No significant difference appered in terms of sit-up, sargent jump, trunk flexion between the 2 groups. In the jumping & stepping test, it showed that there was significant difference(p〈.05) between ice-hockey player(22.73±8.21cm) and soccer player(24.13 ±1.92cm). 4)In the Ventilation, It showed that there was a significant difference(p〈0.01) ice-hockey player(11.18±3.15ℓ/min) and soccer player(8.09±1.79ℓ/min) at rest. In maximum VE, It showed that there were no remarkable difference between ice-hockey player(85.10±21.15ℓ/min) and soccer player(94,72±23.14ℓ/min). 5)In respiration rate, It showed that there were no remarkable difference between ice-hockey player(15.13±2.90n/min, 60.53±9.72n/min), soccer player(12.53±2.97n/min, 63.87±7.50n/min) at rest and maximum exercise. 6)In the Heart Rate, It showed that there was a notable difference(p〈0.05) between ice-hockey player(74.47±9.21beats/min) and soccer player(65.94±7.97beats/min) at rest. In maximum Heart Rate, It showed that there was a notable difference(p〈0.05) between ice-hockey player(180.50±11.34beats/min) and soccer player(189.62±9.84beats/min). 7)In the Oxygen intake per weight per min, It showed that there were no remarkable difference between ice-hockey player(5.17±0.85㎖/kg/min) and soccer player(4.83±1.01㎖/kg/min) at rest. In maximum VO2/W, It showed that there was a significant difference(p〈0.01) ice-hockey player(44.10±8.21㎖/kg/min) and soccer player(54.60±4.35㎖/kg/min). 8)In the all-out time, It showed that there were no remarkable difference ice-hockey player(974.00±217.77 sec) and soccer player(1059±241.82 sec).

      • KCI등재후보

        연쇄알구균 감염에 의한 급성 인후염 후 반응성 관절염 1예

        박은하,도연실,양정채,강미라,서현주,정숙인,손준성,기현균,오원섭,백경란,송재훈 대한감염학회 2004 감염과 화학요법 Vol.36 No.6

        연쇄알구균에 의한 급성 인후염 후 발생한 반응성 관절염은 급성 류마티스열의 개정된 진단기준을 충족하지 못하면서, 지속적 혹은 재발성의 비이동성 관절염과 발열, 홍반성 결절, 일시적 간기능 이상 등을 보이면서 심장염과 무도증을 드물게 동반하는 질환이다. 따라서, 발열을 동반한 급성 관절염 환자에서 감별해야 할 질환 중의 하나이며, 심근염 예방을 위한 페니실린 요법의 적응증 및 기간에 대해서는 아직 이론이 많은 상황으로, 보다 광범위한 연구가 필요하다. 저자들은 연쇄알구균에 의한 급성 인후염 1주 후에 발생한 하지의 다발성 비이동성 관절염과 함께 결절홍반 및 일시적 간기능 이상을 보인 환자에서 PSRA로 진단하고 비스테로이드성 항염증제 및 스테로이드로 성공적인 치료를 하였기에 이를 문헌 고찰과 함께 보고하는 바이다. Poststreptococcal reactive arthritis (PSRA) is associated with recent streptococcal infections. However, PSRA is distinct from acute rheumatic fever by its clinical manifestations: non-migrating arthritis, erythema nodosum or erythema multiforme, and transient elevation of serum transaminases. We experienced a 33-year-old man who presented with fever, arthritis of both knees and ankles, and erythema nodosums on extensor surfaces of lower legs which developed 6 days after the onset of pharyngitis symptoms. Blood and urine cultures were negative. Throat culture was negative for group A β-hemolytic streptococcus. The ASO titers increased up to 2080 IU/mL in sequential monitoring. The result of bone scan was compatible to arthritis of both knees and ankles. There were no signs or symptom of carditis. He showed clinical improvement with anti-inflammatory drugs (naproxen 1,000 mg/day and prednisolone 7.5 mg/d). PSRA should be included in the differential diagnosis of patients presenting with arthritis combined with fever.

      • KCI등재

        새로운 청색 발광 고분자 합성

        박재균,오동원,이우붕 慶北大學校 師範大學 科學敎育硏究所 2007 科學敎育硏究誌 Vol.31 No.-

        Two polyfluorenes, poly[9,9-dioctylfluorenyl-2,7-diyl](P1) and Poly[9,9'-dioctyl fluorene-CO-9,9-bis(4-diphenylaminophenyl) fluoren](P2), were synthesised using the Suzuki coupling reaction. The use of bulky substituents(triphenylamine) in the main chin of P2 improves solubility but exacerbates the twisting in the main chain, further limiting the conjugation lengths and extending π-π* energy gap. The polymers possessed good solubility in common organic solvent such as Toluene, THF, chloroform and so on. The polymers characterized by ¹H-NMR, ¹³C-NMR, GC-MASS, GPC, DSC, TGA, UV -vis., PL. The initial degradation temperatures(T_(id)) of P1, P2 and ADS431BE showed respectively 416 °C, 425 °C and 407 °C, which means all of them have high degradation temperature. Glass Transition temperature(Tg) of P2 showed more high temperature than other polymers(P1, ADS431BE) because of decrease of flexibility by twisting in the main chain. The maximum absorption peak in the UV-vis spectrum of P1, P2 is located all at 390 nm. The maximum emission peaks of P1 and P2 showed all at 438 nm blue region. All of P1 and ADS431BE showed broad wavelength region and had excimer. The P2 showed sharp wavelength region and hardly had excimer. Therefore color purity of the P2 is better than P1, ADS432BE. 연구에서는 유기EL분야에 응용 가능한 새로운 Fluorene계 청색발광 고분자를 합성하기 위해서 Fluorene을 이용해서 단량체인2,7-dibromofluorene, 2,7-dibromo-9,9-dioctylfluorene(M2), 2,7-dibromo-9- fluorenone,9,9-bis(4-diphenylaminophenyl) -2,7-dibromolfluorene(M3)을 합성하였다. Fluorene의 C-9번 위치에 octyl 그룹이나 thphenylamine을 치환하여 유기용매에 잘 용해되도록하였다. P1고분자는 단량체 2,7-dibromo-9,9-dioctylfluorene(M2)을 그리고 P2고분자는 단량체 2,7-dibromo-9,9-dioctylfluorene(M2)와9,9-bis(4-diphenylaminophenyl)-2,7-dibromolfluorene(M3)을 그리고 고분자의 end-capping과 전자 수송능력을 향상시키기 위해 2-(4-bromophenyl)-5-phenyl -1,3,4-oxadiazole을 Pd(0) 촉매로 사용하는 Suzuki coupling 중합법으로 합성하였다. P2고분자에 치환된 triphenylamine은 고분자의 정공 수송능력을 향상시키는 작용을 한다. 각각의 단량체와 고분자의 구조분석은 1H-NMR, 13C-NMR, GC-MASS를 이용하여 분석하였고, 고분자의 열적분석은 DSC, TGA를 통해 측정하였고, 광학적 특성은 PL, UV-vis를 통하여 분석하였다.

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