상악 4전치 후방 견인시 치근 주위 응력 분포에 대한 광탄성법적 분석 : High Pull J-hook Headgear의 효과 The Effects of the High Pull J-hook Headgear

구본준,성재현 慶北大學校 齒科大學 1990 慶北齒大論文集 Vol.8 No.1

The purpose of this study was to investigate the effects of the High Pull J-hook Headgear in retraction the maxillary 4 incisors. The maxillary part of a dry skull that had Angle's Class Ⅱ malocclusion and axes of the central incisors were 60 degrees to the occlusal plane was duplicated with epoxy resin. In this epoxy resin model, the maxillary 4 incisors were retracted by the 1㎜ activated vertical closing loop, High Pull J-hook Headgear with a directional force of 34 degrees to the occlusal plane and 600g in total force, and both of them. The obtained stress distributions around the roots were analysed by three dimensional photoelastic method. The results were as follows; 1. When the maxillary 4 incisors were retracted by the 1㎜ activated vertical closing loop, simple lingual tipping movement patterns were shown. 2. When the maxillary 4 incisors were retracted by the High Pull J-hook Headgear with a directional force of 34 degrees to the occlusal plane and 600g in total force, intrusive bodily movement patterns were shown. 3. When the maxillary 4 incisors were retracted by the 1㎜ activated vertical closing loop and the High Pull J-hook headgear with a directional force of 34 degrees to the occlusal plane and 600g in total force, simple lingual tipping movement patterns and intrusive bodily movement patterns were shown in the same time. J. Kyungpook. Nat. Univ. Sch. Dent. Vol.8, No.1, 91∼103, 1991.

Pulse Oximeter를 이용한 치수생활력측정

이제호,구본경,이종갑 大韓小兒齒科學會 2000 大韓小兒齒科學會誌 Vol.27 No.1

치수 생활력 검사시 전통적인 방법으로 전기치수검사나 온도변화검사 등이 있다. EPT와 ice test 즉, 전기치수검사와 온도변화검사는 치아의 신경학적 반응에 의해 치아의 실활여부를 판단하는 방법으로 환자가 아동일 때는 정확한 반응을 얻기가 어렵고, 환자의 주관적 반응을 판단해야 하므로 객관적이지 못하고, 소아환자에게 좋지 못한 자극을 주어 행동 조절의 문제를 일으키며, 거짓 양성반응과 거짓 음성반응이 나올 수 있다는 등의 한계가 있다. 최근에는 전통적인 방법의 한계를 극복하려는 시도에서 혈관의 보전성을 평가하는 방법인 laser doppler flowmetry와 pulse oximeter를 이용하는 방법이 소개되고 있다. Pulse oximeter의 원리는 두 가지 종류의 파장의 빛을 귀, 손가락 등 생체의 말단에 투과시켜 발산된 빛과 감지된 빛간의 두 파장의 흡수비로 산소포화 정도를 알아내는 것으로서 이에 착안하여 또 하나의 생체 말단인 치아에 이를 적용하여 치아의 실활 여부를 판단하는 것이다. 이 보고에서는 치수 생활력 검사시 pulse oximeter의 사용 가능성에 대해 검증하고 이의 임상적용에 대해 기초적 자료를 제공하고자 함을 목적으로 했는데 생활치에서는 평균 96.3%의 산소 포화도를 실활치에서는 평균 0.0%의 산소 포화도를 얻어냄으로서 pulse oximeter가 치아의 실활여부 판단에 있어 유용한 진단도구로서의 가치가 있다는 것이 밝혀졌다. Traditionally, EPT and thermal tests were used as diagnostic methods for pulp vitality test. The thermal and electrical stimulation tests are the methods to determine the vitality of a tooth based on its neuronal response. These have certain limitations, one of them is the difficulty of approaching the correct result in case of treatment of children. The reason is management problem caused by the unpleasant stimulation. Also, the response from patients are not objective, and false positive or false negative could be happened. Recently, laser doppler flowmetry and pulse oximeter which evaluate vascular integrity are introduced-in an effort of overcoming to limitation of traditional methods. The principle of pulse oximeter is to find out level of oxygen saturation by ratio of the two pulses between emitted light and detected light penetrating them to the termination of body, such as ears or fingers. From this point of view, it can be applied to a tooth to determine its vitality. The objective of this study lies mainly on varifying pulse oximeter as a method of determining tooth vitality and providing basic data of its clinical implementation. The result of the research showed that level of oxygen saturation in vital teeth was average of 96.3% and 0.0% in pulpless teeth. As a comprehensive result, pulse oximeter could be an useful diagnostic equipment in determining of tooth vitality.

도시 초 ·중 ·고교 학생 시력저하 및 굴절이상에 관한 보건조사

양한남,김재찬,구본술 韓國學校保健學會 1988 韓國學校保健學會誌 Vol.1 No.1

The analysis of the visual impairment and refractive errors among 4,004 school children in Seoul in 1986 with ancilliary questionnaire on various socio-environmental and visual factors was conducted. The number of the student with subnormal vision(0.7 or less) was 1,552(38.8%), and the rate of subnormal vision was increased with the higher grading of the school classes. Rate of myopes among the 1,552 students vision 0.7 or less consists of 52% in primary school, 83.5% in middle school, and 94% in high school, and they were increased with the higher grading of the school class. The acutest increase of rates were observed at the stages of 2nd year class of male, and 1st year class of female at the middle school,. Among the glasses-wearer of myopic students of vision 0.5 or less, the rate of adequately corrected cases was 42.5%, whereas the overcorrected in 6.8%, and undercorrected in 49.3%. The main reasons of glasses negligence among the non-possessor of glasses with the vision of 0.5 or less were indicated in prominence of numbers of "no complaints without glasses" (42%), "unawareness of visual disturbance" (20%), "annoyance with wearing glasses"(13.4%), and "no permission from parents" (11.5%) rather than the "economical reasons". The amblyopic components were estimated 126 cases(3.2%) in combination of refractive errors. According to the analysis of ancilliary questionnaire, the-conclusion with the statistical significance was that the myopization of the children's eyes appeared susceptible with a number of socio-environmental factors including the eating habits, length of T.V,watching period and distance, reading distance and type of illumination during near work, and school achievement. The possibility of prevention in some extents of progress of the myopia following the improvement of the relevant environmental factors in younger stage of children would be considired as deducible one.

Pyrantel Pamoate (Combantrin)에 依한 蛔蟲 및 鉤蟲感染의 集團治療

徐丙卨,朴定圭,趙昇烈,姜信榮,魚光本,康世喆,李源宰,李正雨,黃邱一 中央醫學社 1972 中央醫學 Vol.23 No.6

The mass treatment trial of pyrantel pamoate on Ascaris lumbricoides and Ancylostoma duodenale infections was carried out to school-children and inhabitants in rural areas in the central part of Korea. Pyrantel pamoate ("Combantrin") tablet (123 mg base) was administered as a single dose of 10. 0 mg per kg. body weight to a total of 4,198 Ascaris infected cases selected out of 4,436 (41. 6%) positives, who were screened from the total 10,660 collected stool specimens. Of these, only 3,169. cases were followed up after treatment to provide an analysis in this study. Incidentally 161 cases with concomittently infected hookworm were also subjected to assess the efficacy of pyrantel pamoate against A. duodenale. The egg negative conversion rate on A. lumbricoides was 95.3%, and on A. duodenale, 97.5% four weeks following treatment. In failed cases, the egg reduction rates on both of the infections were 97.6% and 97.3% respectively. No side effects and no problem in drug administration were demonstrated. It is concluded that this study confirms the high efficacy of pyrantel pamoate in the treatment of Ascaris lumbricoides and Ancylostoma duodenale infections and also proves the acceptability and safety of this drug in the mass treatment of ascariasis in a population with relatively high worm burden.

관상동맥 질환에서 CD14 유전자형에 따른 세균 및 Heat Shock Protein에 대한 반응의 차이

한주용,최수연,조현주,김화평,강현재,구본권,김남중,김효수,손대원,오병희,박영배,최윤식 대한감염학회 2007 감염과 화학요법 Vol.39 No.1

Background : CD14 is the receptor for lipopolysaccharides and heat shock protein (HSP), which has been suggested being associated with increased risk of coronary artery disease (CAD). We investigated whether the response to infectious agents or HSP is different according to CD14 polymorphism in Koreans. Materials and Methods : Antibody titers to Helicobacter pylori, Chlamydia pneumoniae, and human HSP60 (hHSP60) were measured in 48 patients with stable CAD and in 41 healthy controls by ELISA. CD14 genotype was determined by PCR and high-sensitivity C-reactive protein (hs-CRP) was measured. Results : Seropositivity to C. pneumoniae and H. pylori, and antibody titer to hHSP60 were not significantly associated with the presence of CAD. CD14 genotype distribution was 31 TT (35%), 43 CT (48%), and 15 CC (17%). To compare the response to the infectious organism and hHSP60, we divided study population into 3 groups; CAD patients with non-TT genotype (group I, n=30), CAD patients with TT genotype (group II, n=18), and normal controls (group III, n=41). Seropositivity to C. pneumoniae and H. pylori, and antibody titer to hHSP60 were not significantly different among 3 groups. Though hs-CRP level was significantly different among 3 groups, post-Hoc analysis showed that hs-CRP level was not significantly different between group I and group II (group I: 1.6[1.1-3.5] mg/L and group II: 0.35[0.1-2.0] mg/L). Conclusions : This study suggests that the inflammatory responses to infectious organisms and HSP do not differ according to the CD14 genotype in Koreans. 목적 : 만성적인 세균 감염이나 자가 면역 반응이 동맥경화와 연관되어 있다는 주장이 제기되어 왔다. CD14은 lipopolysaccharides (LPS)와 heat shock protein(HSP)의 수용체로 C(-260)→T 다형성이 관상동맥 질환의 위험과 관련되어 있다고 제안되어 왔다. 본 연구에서는 한국인에서 CD14 다형성에 따른 LPS와 HSP에 대한 반응성을 염증표지자를 측정하여 살펴보고자 하였다. 재료 및 방법 : 안정형 관상동맥 환자 48명과 정상 대조군 41명을 대상으로 Chlamydia pneumoniae, Helicobacter pylori 항체 및 인체 HSP60 (hHSP60) 항체 역가를 enzyme-linked immunosorbent assay (ELISA) 방법으로 측정하였다. CD14 유전자형은 중합효소연쇄반응을 이용하여 결정하였고 hs-CRP를 측정하였다. 결과 : C. pneumonias 및 H. pylori 항체 양성 여부 및 항체 역가, 그리고 hHSP60에 대한 항체 역가는 안정형 관상동맥 질환의 유무와 유의한 상관관계는 없었다. CD14 유전자형의 분포는 TT 30명(39%), CT 31명(40%), 그리고 CC 16명(21%)이었다. 관상동맥 질환 군에서 TT 유전자형은 38%, 대조군에서는 32%로 TT 유전자형과 관상동맥 질환의 유무와는 유의한 상관관계가 발견되지 않았다(P>0.05). CD14 유전자형에 따라 C. pneumonias와 H.pylori 감염 및 hHSP60에 따른 반응에 차이가 있는지 여 부를 알아보기 위해, 관상동맥 질환 군을 다시 TT 유전자형 군과 non-TT 유전자형 군으로 나누어, 전체적으로 세군에서 항체 양성률과 역가를 비교하였다(I군: CD14 TT 유전자형을 가진 안정형 관상동맥 환자, II군: CD14 TT 유전자형을 가진 안정형 관상동맥 환자, III군: 정상 대조군). 세 군에서 C. pneumonias와 H. pylori 항체 양성률 및 hHSP60 항체 역가에는 유의한 차이가 없었다. 세 군사이에 hs-CRP 값에 유의한 차이가 있었지만, post-Hoc분석에서 II군의 hs-CRP 값이 I군에 비해 유의하게 높지는 않았다(0.35 [0.1-2.0] mg/L in group II vs. 1.6 [1.1-3.5]mg/L in group I, P>0.05). 결론 : 본 연구는 한국인에서 CD14 유전자형에 따라 LPS나 HSP에 대한 반응이 유의하게 다르지 않음을 시사한다.

만성 위염전 2 례

박찬규,이동욱,남성진,김추성,조성래,구본천,박영재,허규찬 啓明大學校 醫科大學 1997 계명의대학술지 Vol.16 No.3

위염전은 위의 비정상적인 회전으로 생기는데 급성증에서는 진단이 늦어질 경우 치명적일 수도 있으나, 만성증의 경우는 비특이적 위장관 중상을 나타내며, 치료되지 않을 경우 수년 동안 증상이 지속될 수도 있다. 최근 저자들은 소화불량, 식후 상복부 동통을 주소로 내원한 환자에서 만성위염전 2 례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Gastric volvulus is an abnormal rotation of the stomach. Gastric volvulus may present as an emergency or as a chronic condition. Acute volvulus si potentially lethal if unrecognized, while a chronic volvulus may cause symptoms for years if not treated. Gastric volvulus may be more common than previously estimated. Approximately 700 cases have thus far been documented. In patients with vague upper abdominal pain, bloating, vomiting, early satiety and weight loss, chronic gastric volvulus are reported and the related literature reviewed. The clinical presentation, diagnosis, and treatment are treatment are discussed. Features of acute and chronic volvulus are compared.

Pentacene Thin-Film Transistors and Inverters with Dual-Gate Structure

Koo, Jae Bon,Lim, Jung Wook,Kim, Seong Hyun,Ku, Chan Hoe,Lim, Sang Chul,Lee, Jung Hun,Yun, Sun Jin,Yang, Yong Suk The Electrochemical Society 2006 Electrochemical and solid-state letters Vol.9 No.11

Threshold Voltage Control of Pentacene Thin-Film Transistor with Dual-Gate Structure

Koo, Jae-Bon,Ku, Chan-Hoe,Lim, Sang-Chul,Lee, Jung-Hun,Kim, Seong-Hyun,Lim, Jung-Wook,Yun, Sun-Jin,Yang, Yong-Suk,Suh, Kyung-Soo The Korean Infomation Display Society 2006 Journal of information display Vol.7 No.3

This paper presents a comprehensive study on threshold voltage $(V_{th})$ control of organic thin-film transistors (OTFTs) with dual-gate structure. The fabrication of dual-gate pentacene OTFTs using plasma-enhanced atomic layer deposited (PEALD) 150 nm thick $Al_{2}O_{3}$ as a bottom gate dielectric and 300 nm thick parylene or PEALD 200 nm thick $Al_{2}O_{3}$ as both a top gate dielectric and a passivation layer was investigated. The $V_{th}$ of OTFT with 300 nm thick parylene as a top gate dielectric was changed from 4.7 V to 1.3 V and that with PEALD 200 nm thick $Al_{2}O_{3}$ as a top gate dielectric was changed from 1.95 V to -9.8 V when the voltage bias of top gate electrode was changed from -10 V to 10 V. The change of $V_{th}$ of OTFT with dual-gate structure was successfully investigated by an analysis of electrostatic potential.

Evaluation of Antioxidative Activities of Polymeric Carbohydrates

( Bon Geun Koo ),( Gu Baek ),( Jin Young Park ),( Ji Min Park ),( Min Ju Kim ),( Hyun Seo Ko,),( Byung Jae Ahn ),( Jae Kweon Park ) 한국키틴키토산학회 2012 한국키틴키토산학회지 Vol.17 No.3

The antioxidant capabilities of various polysaccharides including alginate, β-glucan, chitosan, fucoidan and hyaluronate were investigated using three established assays: 2,2-diphenyl-1-picryhydrazyl (DPPH) radical scavenging, ferric reducing antioxidant power (FRAP), and superoxide dismutases (SODs) which are metalloenzymes that catalyze the dismutation of the superoxide anion to hydrogen peroxide and molecular oxygen. The DPPH radical scavenging assay revealed that among the five polysaccharides tested in this study, hyaluronic acid had relatively high antioxidant activity. However, low molecular weight chitooligosaccharides, consisting of glucosamine (GlcN) n, n = 6-9, exhibited slightly higher radical scavenging activity than hyaluronic acid. Interestingly, no DPPH radical scavenging activity was observed from the high molecular weight chitosan. On the contrary, in the FRAP activity measurements, high molecular weight chitosan showed the significant level of activity compared to the chitooligosaccharides, which has shown the similar activity of fucoidan and hyaluronic acid, although it was too marginal. Subsequently, fucoidan has shown the most significant antioxidant activity in SOD assay. These results suggest that antioxidant activity obviously depends on the molecular weight and their structural component as a key factor involved in each reaction mechanisms.

Physiological evaluation of the provisional side-branch intervention strategy for bifurcation lesions using fractional flow reserve.

Koo, Bon-Kwon,Park, Kyung-Woo,Kang, Hyun-Jae,Cho, Young-Seok,Chung, Woo-Young,Youn, Tae-Jin,Chae, In-Ho,Choi, Dong-Ju,Tahk, Seung-Jae,Oh, Byung-Hee,Park, Young-Bae,Kim, Hyo-Soo W.B. Saunders [etc.] 2008 European heart journal Vol.29 No.6

<P>This study was performed to evaluate the functional outcomes of fractional flow reserve (FFR)-guided jailed side-branch (SB) intervention strategy.</P>