Insecticidal toxicities of carvacrol and thymol derived from Thymus vulgaris Lin. against Pochazia shantungensis Chou & Lu.

Jun?Hwan Park,Na-Hyun Lee,Sang-Guei Lee,Hoi-Seon Lee 한국농약과학회 2017 한국농약과학회 학술발표대회 논문집 Vol.2017 No.4

계지의 항염 효과에 관한 연구

박히준,이지숙,이재동,김남재,표지희,강전모,최일환,김수영,심범상,이제헌,임사비나 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

Objectives : Cinnamomi Ramulus (CR), the young twing of Cinnamomi loureirii nees, has been used for treating symptoms related to pain. rheumatic arthritis and inflammation in Korean herb medicine. This study was carried out to investigate the anti-inflammatory effect of CR in vivo and in vitro. Methods : Extracts of CR were prepared and the chemical components of the extracts were examined by gas chromatography-mass spectrometry (GC-MS). The extracts were administrated to the rat paw edema model induced by carrageenan to evaluate the anti-inflammatory effect of CR. The expressions of nitric oxide (NO). prostaglandin E2(PGE2), inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 were also quantified in lipopolysaccharide (LPS)-induced RAW 264.7 macrophages to survey the effect of CR in vitro. The main components were cinnamaldechyde and coumarin. Results : We examined the anti-inflammatory activity of the 80% ethanol extract of Cinnamomi Ramulus in vivo by using carrageenan-induced rat paw edema model. Maximum inhibition of 54.9% was noted at the dose of 1000㎎/㎏ after 2 hours of drug administration in carrageenan-induced rat paw edema and this showed a potent anti-inflammatory effect. Conclusions : The results showed that Cinnamomi Ramulus suppressed dose-dependently LPS-induced NO production in RAW 264.7 macrophages and also decreased iNOS protein expression. Cinnamomi Ramulus also showed a significant inhibitory effect in LPS-induced PGE2 production and COX-2 expression.

이중관에서의 응축열전달 최적화에 관한 연구

박일환,박준석 한국기술교육대학교 2003 論文集 Vol.10 No.1

The present study has been conducted entropy analysis on a saturated R134a vapour flowing through and condensed outside or inside horizontal cooling tube. The flow condensation heat transfer performance is dominated by the phase change process with low mass flux, and by two phase flow condensation with high mass flux. And there exists an optimum mass flux and a tube diameter ratio that results in minimum of entropy generation.

촉각센서를 위한 실리콘 마이크로다이어프램 배열의 제조

박기열,심준환,류인식,조찬섭,이종현 경북대학교 센서기술연구소 1994 센서技術學術大會論文集 Vol.5 No.1

Silicon diaphragm arrays were fabricated by silicon micromachining using porous silicon. Fabricated diaphragms consist of 3x3 array. The thickness of diaphragm is 5μm and theire size are 200x200, 300X300 and 400X400μm^(2), respectively. Several % of resistance change is observed, when stress was applied at diffused resistor on the diaphragm. Microdiaphragm arrays were easily fabricated by silicon micromachining using porous silicon, and we confirmed feasibilty of application at tactile sensor.

단기배양을 통한 말초혈액 CD34 양성세포의 체외증폭

박상준,김철희,배광봉,김현수,김종숙,윤환중,조덕연,김삼용 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1

Background: It is suggested that clinical practice in the areas of bone marrow transplantation and gene therapy might rely on the ex vivo expansion of hematopoietic stem/progenitor cells. However, the condition for ex vivo expansion of hematopoietic progenitor cells is not well established. The authors pursued a series of experiments to define the proper conditions for the expansion of hematopoietic cells in the short-term liquid suspension culture of mobilized peripheral blood CD34+ cells. Methods: 1.0ml cultures were initiated with 9×10^3 PB CD34+ cells, which were isolated from PB mononuclear cells (MNCs) by high-gradient cell sorting, in 12 well plates with the various combinations of hematopoietic growth factors(HGF). The following recombinant human HGFs were used: stem cell factor(SCF) 100ng/ml, granulocyte colony-stimulating factor(G-CSF) 100ng/ml, GM-CSF(granulocyte, macrophage colony-stimulating factor) 100ng/ml, interleukin-1 beta(IL-1B) 1ng/ml, interleukin-3(IL-3) 20ng/ml, interleukin-6 (IL-6) 100ng/ml. At the end of culture, colony-forming cells were evaluated by semisolid clonogenic assay. Results: 1) Using the high-gradient magnetic sorting system, CD34^+ cells were isolated with a yield of 40 3% 2) In 7 day culture of PB CD34^+ cells(9×10^3 cells), nucleated cells expanded mean 10×10^3(range, 9 to 20×10^3) with the addition of SCF alone, 35×10^3(range, 10 to 60×10^3) with SCF plus G-CSF plus GM-CSF, and 130×10^3(range, 40 to 300×10^3) with the combination of SCF, G-CSF, IL-1, IL-3, IL-6, GM-CSF. In 14 day culture, nucleated cells expanded 10×10^3 to 1,860×10^3 with combination of human hematopoietic growth factors. 3) In 10 day culture without medium change of PB CD34^+ cells, CFU-GM numbers expanded 16. 5 fold(range, 7 to 59 fold) with the addition of SCF plus G-CSF plus Il-1 plus IL-3, 31.3 fold(range, 20.5 to 101.1 fold) with the combination of SCF, G-CSF, IL-1, IL-3, GM-CSF. In 14 day culture with or without medium change of PB CD34^+ cells was inferior to 10 day culture for CFU-GM expansion. 4) There was no significant difference for CFU-GM expansion between five growth factors(SCF,G-CSF,IL-1,IL-3,GM-CSF) and six growth factors(five growth factors plus IL-6). Conclusion: The authors could confirm that short-term suspension culture of peripheral blood CD34+ cells could expand hematopoietic progenitor cells. Ten-day culture with medium change of CD34+ cells with the addition of five growth factors, i.e. SCF, G-CSF, IL-1B, IL-3, and GM-CSF, might be the most efficient in this system.

고량강의 항염증 작용에 대한 연구

박히준,이제현,김수영,심범상,구헌종,강전모,최일환,이재동,김남재,이지숙,임사비나 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

Objective : The use of herbal therapy is becoming an increasingly attractive approach for the treatment of various inflammatory disorders. The Alpiniae officinari Rhizoma is popular in Aisa as a traditional herbal medicine. Alpiniae officinari Rhizoma is a species of the ginger family(Zingiberacease). Method : This study was performed to investigate the anti-inflammatory effect of Alpiniae officinari Rhizoma extract by the methods of "carrageenan induced paw edema" and "Lipopolysaccharide-induced inflammatory mediators in mouse macrophage RAW 264.7 cells". Result : We suggest that Alpiniae officinari Rhizoma extract decreased paw volume induced by plantar injection of carrageenan. Also Alpiniae officinari Rhizoma extract inhibited nitric oxide, prostaglandin E₂production and induced nitric oxide synthase, cyclooxygenase-2 protein expression in Mouse macrophage RAW 264.7 cells stimulated with lipopolysaccharide. Conclusion : This study shows that Alpiniae officinari Rhizoma extract seems to have anti-inflammatory effect by inhibition of nitric oxide, prostaglandin E_(2) production and nitric oxide synthase, cyclooxygenase-2 protein expression.

돼지의 經濟形質에 미치는 品種과 檢定時期間 相互作用의 效果

朴英一,李俊佑,金洛煥 서울大學校農科大學 農業開發硏究所 1991 서울대농학연구지 Vol.16 No.1

1984年 7月부터 1990年 9月까지 공인 種豚 能力檢定所에서 能力檢定된 Yokshire種, Landrace種 및 Duroc種 수퇘지 5,604頭에 대한 資料에 근거하여 品種과 檢定開始 時期間 相互作用이 돼지의 日當 增體量, 飼料要求率 및 등脂肪 두께에 미치는 效果를 추정하였으며 資料의 統計分析에는 最小自乘法을 이용하였다. 品種과 檢定開始 時期間 相互作用의 效果는 飼料要求率과 등脂肪 두께에 대하여 統計的 유의성이 있었으나 日當 增體量에 대하여는 유의성이 없었다. 세 品種間 飼料要求率의 차이는 5-6月 및 7-8月에 檢定이 開始된 돼지에 비하여 1-2月에 檢定이 開始된 돼지에서 작게 추정되었다. Duroc種의 등脂肪 두께에 대한 Yorkshire種과 Landrace種의 순위는 檢定開始 時期에 따라 다른 경향이 있었다. The effect of the interaction between breed and testing time on average daily gain, feed efficiency and backfat thickness was estimated on the basis of the record from 5604 boars of Yorkshire, Landrace and Duroc breeds performance tested at the Korea Swine Testing Station from July, 1984 to September, 1990. The data were statistically analysed by the least squares method. The effect of the interaction between breed and testing time was statistically significant for feed efficiency and backfat thickness, but was not significant for average daily gain. The differences of feed efficiency among the three breeds were smaller in the boars which started the test in January-February as compared with the boars which started the test in May-June or July-August. In all testing times, the Duroc had the thickest backfat, but the rankings of the Yorkshire and Landrace for the backfat thickness were inconsistent depending on the time when the test was started.

민간 경호·경비원들의 의식구조와 가치관에 관한 연구

박준석,최현식,정성숙,김진환,정석현 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.4

The aim of this study was to investigate Consciousness and Value on Private Bodyguard and Security. I started to search from 7. January. 2004 to 20. May. 2004. so totally I searched for 5month, As a result, I got 526 papers of questionnaire and dropped 26 papers of them because of insincere answers from responders, So I used 500 papers for the research that I am doing. The method of One-Way ANOVA was used to verify the mean ratio and LSD multiple range test was also used for the verification when there was a slight difference among the objected group, All data were analyzed by SPSS 11.0 producer. The results of this study are like the below: 1) The result In the case of ages showed that significant difference(p<.05) companies consciousness were Private Bodyguard and Security for structure of consciousness. 2) The result In the case of Educational Credentials showed that no significant difference self consciousness, welfare conscious ness, social consciousness, companies consciousness were Private Bodyguard and Security for structure of consciousness. 3) The result In the case of work duration showed that significant difference(p<.05) self consciousness were Private Bodyguard and Security for structure of consciousness. 4) The result in the case of monthly income showed that no significant difference self consciousness, welfare conscious ness, social consciousness, companies consciousness were Private Bodyguard and Security for structure of consciousness. 5) The result in the case of working time showed that significant difference(p<.05) self consciousness, social consciousness, companies consciousness were Private Bodyguard and Security for structure of consciousness.

써키트트레이닝 부하강도에 따른 고등학교 유도선수들의 체력향상 효과

박순진,김준환 龍仁大學校 武道硏究所 2003 武道硏究所誌 Vol.14 No.1

The research which it sees bitterly the circuit training this against the physical strength improvement effect of the high school induction bow to examine and it was for. 20 person Kyonggi-Do subject matter K high school induction staffs in 10 person two group A group and 10 person B group it shared in the object and beriberi of the different load burglar the kit Tray ning it executed bitterly. Week 3 month, possibility, Friday, A group to execute load burglar 50% B group per the each item to execute with load burglar 80% the disturbance hour did 30 middle age. Bitterly the circuit training the item which is necessary to the induction bow selected 12 items. The Tray of 8 weeks circuit training with after words it came down a same conclusion after executing. There is a difference which first, the Tray ning 8 weeks considers statistically from after B group the Tray ning war results comparison hour B group A group more is a possibility of knowing the fact that the muscular power improves a lot. There is a difference which first, the training 8 weeks considers statistically from after B group the training war results comparison hour B group A group more is a possibility of knowing the fact that the muscular power improves a lot. The secondth, training 8 weeks there is a difference which considers statistically from after B group and the training war results comparison hour B group A group more is a possibility of knowing the fact that the pure foot power improves. The thirdth, training 8 weeks there is a difference which considers statistically from after B group and the training war results comparison hour B group A group more pliability some is a possibility of knowing the fact that it improves. The fourthth, training 8 weeks there is a difference which considers statistically from after B group and the training war results comparison hour B group A group more agile characteristic improves a lot is a possibility of knowing the fact that. Fifth, the training 8 weeks there is a difference which considers statistically from after B group and the training war results comparison hour B group A group more the core abolition old calendar some is a possibility of knowing the fact that it improves. Sixth, the training 8 weeks there is a difference which considers statistically from after B group and the training war results comparison hour B group A group more muscle endurance some is a possibility of knowing the fact that it improves. When it tries to the result of over, the circuit training from of 8 weeks training under high school judo player improves the physical strength of the induction bow and it gives the help which even from in the that is many in muscular power improvement the possibility of knowing the thing it was.

血栓症과 打撲性 充血 및 高脂血症에 順氣導痰湯 및 化瘀湯 미치는 影響

朴元煥,崔達永,文濬典 동국대학교 한의학연구소 1993 東國韓醫學硏究所論文集 Vol.2 No.1

To see both Shunqidaotantang(dissipate phlegm and promote vital energy circulation) and Huayutang(blood circulation and disperse blood stasis) influencing on thrombosis, contusion-hyperemia, and hyperlipidemia, at first we measured the density of FDP, the quantity of fibrinogen, prothrombin time, and the number of platelet of rat taken thrombosis by endotoxin. Secondly we measured the increase-rate of "paw swelling", the number of platelet, the quantity of fibrinogen, and prothrombin time of rat taken contusion-hyperemia. And then we measured the quantity of total cholesterol in serum and of H.D.L-cholesterol and of triglyceride and of phospholipid arid of P-lipoprotein, its weight, and the variation of the quantity of electrolyte of rat taken hyperlipidemia by the oral-injection of choleserol. As a result, we can conclude as follows : 1. Out of the test of thrombosis, we can recognize not only the noticeable increae of the number of platelet and the quantity of fibrinogen, but also the noticeable decrease of prothrornbin tirne and the density of FDP in case of Shunqidaotantang-injected rat and Huayutang-injected rat. 2. Out of the test of contusion-hyperemia, we can recognize not only the noticeable increase of the number of platelet and the quantity of fibrinogen, but also the noticeable decrease of prothrombin time and "increase-rate of paw swelling" in case of Shunqidaotantang-injected rat and Huayutang-injected rat. 3. Out of the test of hyperlipidemia, at first we can recognize that test rat s weight increased as close as that of normal rat. And we can recognize the noticeable decrease of the triglyceride and phospholipid and P-lipoprotein. Also, in case of the variation of electrolyte we can recognize the decrease of calcium and potassium in Shunqidaotantang-injected rat, and of sodium and magnesium in Huayutang-injected rat. Thus, as the above-mentioned, in covering thrombosis, contusion-hypermia, and hyperlipidemia, the effect of Shunqidaotantang and Huayutang can be recognized. Granting that Huayutang reveals its effectiveness in thrombosis and contusion-hyperemia, and Shunqidaotantang in hyperlipidemia, it can be inferred that contusion-hyperemia is like model of blood stasis form as thrombosis and hyperlipidemia "phlegm-retention diseases form", and both phlegm-retention and blood stasis have correlation each other.