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      • KCI등재후보

        조혈모세포이식 환자에서 발생한 Cytomegalovirus 질환의 특징 : 일개 대학변원에서 최근 10년간의 경험

        최수미,이동건,박선희,김시현,김유진,민창기,김희제,이석,최정현,유진홍,김동욱,이종욱,민우성,신완식,김춘추 대한감염학회 2009 감염과 화학요법 Vol.41 No.1

        Background : Studies on cytomegalovirus (CMV) diseases in Korean hematopoietic stem cell transplant (HSCT) recipients are lacking and do not reflect the recent trends of advances and changes. Therefore, we tried to analyze the clinical features of CMV diseases in HSCT recipients over the past 10 years at a tertiary university hospital in Korea. Methods : Retrospective review of medical records was done for all adult HSCT patients who received transplant at the Catholic HSCT Center from January 1998 to January 2008. Results : Forty-four cases (2.2%) of CMV diseases were identified. CMV pneumonia was diagnosed in 17 patients, retinitis in 16 patients, enterocolitis in 7 patients, esophagitis 1 patient, gastritis in 1 patient, duodenitis in 1 patient, and hepatitis in 1 patient. The median onset of symptom was 90 days after transplantation. Late CMV diseases accounted for 47.7%. CMV related death varied from 0 to 58.8% according to the involved organ. CMV retinitis was diagnosed relatively later in the course of transplantation mostly in patients who had chronic graft versus host disease (GVHD). On the contrary, CMV enterocolitis mainly occurred in patients who suffered from acute GVHD. The overall concurrent CMV reactivation was documented to be 63.6%: the concurrent CMV reactivation was observed only in 37.5% of patients with retinitis. Conclusions : We observed some differences in the pattern of CMV disease manifestation according to the involved organ and reconfirmed the fact that CMV pneumonia is the most common and fatal disease in HSCT recipients. Additionally, CMV retinitis was not uncommon in HSCT recipients. Since specific marker does not exist in predicting retinitis, regular ocular examination should be done thoroughly, especially in patients with chronic GVHD.

      • KCI등재

        동강의 어류상과 생태학적 군집분석

        최준길 ( Jun Kil Choi ),오사무미타무라 ( Osamu Mitamura ),이동준 ( Dong Jun Lee ),신현선 ( Hyun Seon Shin ) 한국환경생태학회 2008 한국환경생태학회지 Vol.22 No.6

        2006년 5월부터 2007년 5월까지 동강의 어류상과 생태학적 군집분석을 조사한 결과는 다음과 같다. 조사된 어종은 총 10과 31종이었다. 총 31종의 어종 중 일차담수어가 26종, 주연성 담수어가 5종으로 나타나 일차담수어의 구성비가 매우 높았다. 우점종은 참갈겨니(Zacco koreanus) 55.73%, 아우점종은 쉬리(Coreoleuciscus splendidus) 7.15%였으며, 우세종은 배가시리(Microphysogobio longidorsalis) 6.12%, 어름치(Hemibarbus mylodon) 4.87%, 참종개(Iksookimia koreensis) 4.49% 등이었다. 한국고유종은 묵납자루(Acheilognathus signifer), 줄납자루(A. yamatsutae), 가는돌고기(Pseudopungtungia tenuicorpus), 쉬리(C. splendidus), 긴몰개(Squalidus gracilis majimae) 그리고 어름치(H. mylodon) 등 19종(61.29%)으로 고유종의 빈도가 매우 높았으며, 천연기념물이 1종, 환경부지정 멸종위기 야생동물 II급 종이 5종으로 각각 확인되었다. 예상되는 종수(기대종)의 분석 결과, 동강의 전 조사지점에서는 18(지점 4, 5)∼22종(지점 3)이 서식하고 있을 것으로 나타났으며, 유사도 분석은 62.28%(지점 1과 2)∼84.13%(지점 1과 5)의 범위로 나타났다. 따라서 동강유역은 어류가 서식하기에 매우 적합한 수환경을 유지하고 있으며, 각 조사지점별 수환경도 매우 유사한 것으로 판단된다. The ichthyofauna and ecological community analysis in the Dong River, Korea, were investigated from May, 2006 to May, 2007. During the surveyed period, 31 species belonging 9 families were collected. Total of 31 species(primary freshwater: 26 species, peripheral freshwater: 5 species) were found with the primary freshwater fishes being highest. Dominant species was Zacco koreanus(55.73%), and subdominant species was Coreoleuciscus splendidus(7.15%). Also, Microphysogobio longidorsalis (6.12%), Hemibarbus mylodon(4.87%), Iksookimia koreensis(4.49%) were numerous. There were 19 Korean endemic species(61.29%), including Acheilognathus signifer, A. yamatsutae, Pseudopungtungia tenuicorpus, C. splendidus, Squalidus gracilis majimae, H. mylodon. Among them, 1 species was identified as qualifying for possible desigantion as a natural monument catergory, and 5 species were identified for designation required to protect under a wildlife category. As result of expected number of species according to rarefaction curve, the expected species of the Dong-river ranged from 19(St. 4, 5) to 22(St. 3) and result of similarity analysis ranged from 62.28%(St. 1 and 2) to 84.13%(St. 1 and 5). In conclusions, we could define that the Dong-river has a very good water conditions as habitat of fish, and habitat conditions also are very similar in every survey sites.

      • 韓國河川의 流出率과 流出指標로서의 洪水直前 流量

        金熙鍾,柳又秀,金佳鉉,申東守,韓健模,全裕燦 東亞大學校 大學院 1984 大學院論文集 Vol.9 No.-

        This paper is a study on relation between run-off ratio and antecedent discharge, run-off ratio and antecedent discharge per unit area, antecedent discharge and antecedent precipitation, by the data from the five major river basins in Korea and the small river basins in Pusan. The Nak-Dong rivers(An-Dong upper stream) f=0.4780+0.0124 ln qA r=0.99 qA=0.3368e0.1101R r=0.99 f=0.5793+0.0146 ln(qA/A) r=0.99 The Nak-Dong rivers except Ga-song station f=0.2017-0.0840 ln qA r=0.75 f=0.7012+0.0750 ln(aA/A) r=0.71 The Han rivers f=-0.0035+01267 on qA r=0.75 f=1.1311+0.1263 ln(qA/A) r=0.71 L=302.9064-43.8490 ln qA r=0.84 The Geun rivers(Mu-sin Cheon) f=0.295+0.1823 ln qA r=0.93 f=0.8417+0.1823 ln(qA/A) r=0.93 L=40.0456+62.0346 ln qA r=0.94 The Yeong-san rivers f=0.3766+0.0598 ln qA r=0.79 f=0.8084+0.0599 ln(qA/A) r=0.79 The Seom-jin rivers f=-1.3875+0.6505 ln qA r=0.92 f=2.1633+0.3465 ln(qA/A) r=0.76 Small river basin in Pusan f=0.3635+0.1120 ln qA r=0.87

      • 한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

        양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

        The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

      • 칼라영상 입 ·출력 시스템의 칼라보정 알고리듬에 관한 고찰

        신현덕,김일태,임재권,윤동한 國立金烏工科大學校附設生産技術硏究所 1995 産業技術開發硏究 Vol.11 No.-

        Colors reprodued by color image processing system are affected by various physical factors and environmental conditions. Therefore it is difficult to reproduce the original object color accurately. Thus color calibrations of the input and output data of color image processing system based on spectral distributions are required. We propose a color calibration algorithm by considering spectral characteristic of the chosen color reproduction system which can be applied to device independent color reproduction using characteristic vectors of surface reflectance. The method comprised of two steps. The first step is color analysis step which reproduces the original object color from the camera output using color characteristic vectors. The second step is color synthesis step which displays the original color accurately on the monitor by considering the monitor's phosphor spectra. The spectral responsivities of camera sensors and phosphor spectral characteristics of a given monitor are evaluated. Also, to evaluate color reproducing characteristic we applied the proposed color calibration algorithm by choosing Macbeth ColorChecker's twenty four color spectra as a test color set. As a result, we reconstruct the actual color very closely on monitor using the proposed color calibration algorithm.

      • 전기발광소자에서 프탈로시안 카퍼의 역할

        申東明,金正賢 弘益大學校 科學基術硏究所 1999 科學技術硏究論文集 Vol.10 No.2

        Interfacial properties of electrode and organic thin layer is one of the most important factor in performing a light emitting diodes(LED). Phthalocyanine copper was used as a buffer layer to improve interface characteristic, so that device efficiency was improved. In this study, LEDs were fabricated as like structures of ITO / N,N' - diphenyl - N,N' - di(m-tolyl) - benzidine(TPD) / 8-Hydroxyquinoline aluminum(Alq) / Al and ITO / N,N'- diphenyl - N,N' - di(m-tolyl) - benzidine(TPD) / 2- (4-biphenylyl) - 5(4-tert-butyl-phenyl) -1,3,4 -oxadiazole(PBD) / Al. In these devices, CuPC was layered at electrode/organic layer interface. As position is changing and thickness is changing, devices showed different phenomena respectively. We showed in this study that luminescence efficiency was improved with CuPC layer in LEDs. Characteristic of CuPC will be discussed with I-V curve, EL.

      • 용매추출에 의한 2-propanol회수에 관한 연구

        신현심,정상훈,박동원 東亞大學校 海洋資源硏究所 1994 硏究論文集 Vol.7 No.2

        The experimental binodal curve and tie line data were determined for ternary systems of 2-propanol-water with isoamylacetate and 1-butanol as solvents at 25℃. Consistency of the experimental data for several correlations was investigated, the experimental tie line data were correlated with NRTL model and the parameters in NRTL model were estimated and the calculated values of tie lines were predicted.

      • KCI등재

        경남지역의 채소류와 화훼류 해충에 관한 조사

        신현열,이동운,추호렬,박정규 경상대학교 농업생명과학연구원 2001 농업생명과학연구 Vol.35 No.-

        본 연구는 1996년 경남지역 주요 채소류와 화훼류 작물에 발생하는 해충과 기타 주요 해로운 동물의 종류를 알아보기 위하여 수행하였다. 오이에서는 오이총채벌레와 꽃노랑총채벌레를 포함하여 7과 8속 10종이 확인되었으며, 양파에서는 알톡토기를 포함한 4과 4속 4종이 조사되었고, 배추에서는 배추좀나방과 담배거세미나방을 포함한 10과 13속 14종이 확인되었다. 거베라에서는 아메리카잎굴파리와 점박이응애, 담배거세미나방을 포함한 8과 8속 10종이, 글라디올러스에서는 명주달팽이와 민달팽이, 들민달팽이를 포함하여 6과 7속 8종이, 국화에서는 민달팽이와 꽃노랑총채벌레를 포함한 10과 13속 14종의 해충이 확인되었다. Insect pests were surveyed on the major vegetable and floricultural crops in Gyeongnam province in 1996. In addition, some other important animal pests were included in this survey. Ten species of 8 genera in 7 families including Thrips palmi and Frankliniella occidentalis were found from cucumber; 4 species of 4 genera in 4 families including Bourletiella hortensis from onion; 15 species of 14 genera in 11 families including Plutella xylostella and Spodoptera litura from Chinese cabbage; 10 species of 8 genera in 8 families including Liriomyza trifolii, Tetranychus urticae and S. litura from gerbera; 6 species of 7 genera in 8 families including Acusta despecta, Incilaria contusa and Deroceras varians from gladiolus; and 14 species of 13 genera in 10 families including I. contusa and F. occidentalis from chrysanthemum.

      • 정향 수침액에 의한 아나필락시의 억제 효과

        신태용,김상현,이석봉,엄동옥,임종필,이은희,김형민 우석대학교 의약품개발연구소 1996 藥學硏究誌 Vol.1 No.-

        The current study evaluates the capacity of Caryophylli Flos water extract(CFWE) to regulate immediate allergic reaction by control of histamine release. CFWE was found to exhibit a ingibitory activity on the compound 48/80-induced anaphylaxis. CFWE inhibited the serum histamine release induced in anaphylaxis by compound 48/80. CFWE was also showed a dose-depent activity on the conpound 40/80-induced histamine release from the highly purified population of Alcian Blue-positive peritoneal mast cells. This result suggest that CFWE may be useful for the prevention and treatment of allergy related disease.

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