관동맥질환에서 저밀도 지단백 입자 크기의 분포

임효영,김인숙,승기배,강동헌,전두수,장기육,박준철,이수영,홍순조,최규보 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.8

한랭노출과 고혈압의 연관성

장태원,김윤규,윤동영,이창희,홍영습,신해림,정갑열,김준연 大韓産業醫學會 2001 대한직업환경의학회지 Vol.13 No.4

Objectives : This study was carried out to suggest preventive methods for hypertension in cold-exposed workers. Methods : In 11 refs·iteration industries, 68 workers working in refrigerated areas more than one time per day were selected as the exposed group, and 68 workers not exposed to cold were selected as the control group. We interviewed the subjects with a questionnaire covering occupational history, and conducted clinical and laboratory tests including measurements of blood pressure and core temperature. Results : The systolic blood pressure in the exposed group(130.0±13.3 mmHg) was significantly higher than that recorded In the control group(118.3±12.1 mmHg), as was the diastolic blood pressure in the exposed group(82.7±8.5 mmHg) versus the control group(77.4±8.7 mmHg). The core temperature in the exposed group(36.1±0.7℃) was significantly lower than that experienced in the control group (36.4±0.5℃). In logistic regression analysis, age, cold exposure severity and milk intake were significant variables, with odds ratios of 5.204(95 % CI 1.440∼18.812), 2.674(95 % CI 1.080∼6.618), and 0.364(95 % Cl 0.141∼0.942) , respectively. Conclusions : Our study suggests that cold-exposed workers have higher a higher risk of hypertension, and that their core temperature is lower. Risk factors affecting hyper-tension of cold-exposed workers include age, cold exposure severity and milk intake. For the prevention of hypertension, cold-exposed workers should minimize cold-exposure time as much as possible.

아급성 Ethanol 중독시 고뇨산혈증에 미치는 Pyrazinamide의 영향

장윤경,강우규,김동훈,최종원 慶星大學校 環境問題硏究所 1992 環境硏報 Vol.2 No.1

Ethanol 투여후 pyrazinamide 처리로 유도되어지는고 뇨산혈증의 발생 기전과 규명하고자 ethanol을 rat에 아급성적으로 투여하고 pyrazinoic acid의 대사 과정, 뇨산의 혈증 농도, 뇨산의 생합성 및 분해과정에 관여하는 효소의 활성 변화를 비교검토하였을 때 pyrazina-mide의 대사산물인 pyazinoic acid의 생성과정은 증가되었으나 pyrazinoic acid의 분해과정은 영향이 없었다. Ethanol 아급성 중독상태에 pyrazinamide를 투여하였을 때 혈액중의 뇨산 농도는 대조군에 비해 약 123% 정도현저히 증가되었다. 뇨산의 분해 효소인 urixase의 활성변화와 생합성에 관여하는 adenosine deaminase, purine nucleoside phos-phorylase 및 guanine deaminase의 활성변화에는 별다른 관련성이 없었으며 선책적으로 xanthine oxidase 활성만이 유도되어 나타나는 결과였다. In the present work, the purpose was to onbserve the effect of subacute ethanol intoxication on the changes of purine metabnolic pathway after pyraxzinamide administration in rats. In vitro test, it was observed that pyrazinamide deaminasing-enzyme activity was significantly increased and pyrazinoic acid oxidizing-enzyme activity was not affected by ethanol-administrated rat's cytosolic liver. When uric acid level in blood was estimated after pyrazinamide treatment, the blood level was increased in comparison to control group of subacute ethanol intoxication. Ethanol administration did not affect activities of guanine deaminase, adenosine deaminase, purine nucleoside phosphorylase and uricase, on the other hand, xanthing oxidase activity was significantly increased as compared with control. These results suggest that hyperuricemia incuced by the administration of pyrazinamide after subacute ethanol intoxication may be result from the selective increase of xanthine oxidase activity.

이온교환법에 의한 탈질소공정개발의 기초연구 : 회분식 실험 Batch Experiment

이동환,채용곤,김장일,윤태경,주창식,이민규 동의대학교 기초과학연구소 1998 基礎科學硏究論文集 Vol.8 No.1

Ion exchange performance to remove nitrate in water was studied using commercially available strong base anion exchange resin of Cl^- type in the batch reactors. Anion exchange resin was more effective than activated carbon or zeolite. With large resin amount or high temperature or low initial concentration, nitrate removal characteristics for a typical gel-type resin was increased. The curves showed the generally accepted selectivity sequence as SO₄^2-$gt;NO₃^-$gt;NO₂^-$gt;HCO₃^-.

물결합재비 및 단위수량에 따른 고유동콘크리트의 제공학적 특성에 관한 실험적 연구

김규용,한장현,신동주,신홍철,김무한 忠南大學校 産業技術硏究所 1998 산업기술연구논문집 Vol.13 No.1

Recently the study on high flowing concrete which has high workability and non-compacting is being proceeded actively in the university and corporative laboratory. There are some cases that has been applied to the field. This high flowing concrete has higher fluidity and segregation resistance than Plain or flowing concrete. And it is being focused as a remarkable know-how which can make high-quality concrete and reduction effect of labor force. This properties of high flowing concrete are influenced by the relationship of several factors; binder content water binder ratio and unit water content. It is the aim of this study to propose reference data at mix design of high flowing concrete, after comparing and analyzing the fluidity and strength properties of high flowing concrete according to water binder content ratio and unlit water content.

균일가열법으로 제조한 반용융 A390합금의 미세조직 및 성형성

임수근,윤병은,장동훈,엄정필,김득규 慶尙大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.13 No.-

Microstructure of hypereutectic Al-17wt.% Si alloy, fabricated by mechanical stirring and by reheating at semi-solid state, was investigated by optical microscope. Flow behavior semi-solid metal also was investigated at diffentent mould temperatures 280℃, 290℃ and 300℃ . Size of silicon particles were increased over 100㎛ durig solidification as a result of stirring. It is considered as microstructural coarsening by bonding between neighbouring primary silicon particles during stirring of slurry. In case of reheating at semi-state, however, primary silicon particle was not increased at size of 40㎛ and nearly spherical aluminum solde particle also was improved when solid fraction was 0.7 at mould temperature of 300℃ than other conditions.

냉각판을 이용한 반응고 A356합금의 미세조직

임수근,윤병은,장동훈,엄정필,김득규 慶尙大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.13 No.-

In this study, microstructure, size of primary α, solid fraction and hardness of A356 Al alloy were investigated. Semi-solid A356 alloys were obtained by semi-solid continuous casting apparatus consists of melting furnace, formation apparatus of granular primary α and continuous casting apparatus. Size of primary α and solid fraction were decreased with decreasing temperature, and with increasing volume of cooling water. At the cooling water temperature of 15℃ and cooling water volume of 18.2ℓ/min, the sizes of primary α phases were decreased up to 40㎛, and fraction solid was 0.68.

비기능성 부신피질암 1례

하달봉,이경섭,손형규,이준희,원유홍,김동훈,장태정 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

비기능성 부신피질암은 발생 빈도가 극히 드문 악성 종양이며, 내분비학적 임상증상이 없어 주로 복부 종물에 의해 우연히 발견된다. 그래서 대부분 종양의 크기가 거대하고 전이로 진행된 경우가 흔하며, 절제술만으로는 치유 불가능한 경우가 많아 예후가 불량한다. 최근 저자들은 약 10년간 간헐적인 좌측 측복통과 흉부 압박감으로 내원하여, 이학적 검사 및 방사선학적 검사상 복부 종물이 확인되고 생화학적 검사에서 비기능성으로 판명된 52세 남자 환자에서 근치적 신절제술을 시행하여 병리조직검사상 비기능성 부신피질암으로 진단되었기에 문헌 고찰과 함께 보고하는 바이다. Nonfunctioning adrenocortical carcinoma is extremely rare, which is diagnosed most often in older man because of mass effect. Most tumors are discovered too late for curative resection, and advanced tumors are associated with a poor prognosis. Herein we report on a 52-year-old man with nonfunctioning adrenocortical carcinoma, treated by radical nephrectomy.

Synthesis of Novel Polythiol for Plastic Optical Lens and its Ophthalmic Lens

Dong Gyu Jang,Myeong Ja Kwon,Soo Min Lee,노수균,Jong Hyo Kim,Wen Yi Jin,Jin Moo Seo 대한화학회 2009 Bulletin of the Korean Chemical Society Vol.30 No.10

Novel polythiol materials of urethane lens series for plastic optical lens were synthesized from polyol materials via thioisouronium of thiourea with c-HCl in refluxing aqueous solution, in which polythiol material was carried out from hydrolysis of thioisouronium by ammonia water. Their structure properties were identified by EA, EI-MS,FT-IR, 1H and 13C NMR spectroscopies and TGA. Their ophthalmic lenses as polythiourethane material were prepared by thermal curing to an injected glass mold using the evenly solutions of diisocyanates series (TDI, XDI, HDI or IPDI) with polythiols. Polythiourethane shows that the strong stretching mode for SH group of polythiol disappeared in FT-IR spectra after thermosetting polymerization. Thermal deformation starting temperature of ophthalmic lenses was determined by TMA. Ophthalmic lenses made from characteristic polythiol and diisocyanate series have transparency, colorless and good impact strength, in which thermal resistance and impact strength of ophthalmic lenses were influenced by diisocyanate series. Physical properties of ophthalmic lens have contrast thermal resistance with impact strength. The property of thermal resistance and impact strength for respective ophthalmic lenses was examined by TMA and drop ball test.

Recurred Localized Amyloidosis of Bladder Causing Hematuria

Dong Gyu Jang,Sun Ju Lee,Jongkeun Kim,Ji-Won Hwang,Changhee Yoo,Cheol Young Oh,Sun Young Jun,Jin Seon Cho 대한비뇨기종양학회 2011 대한비뇨기종양학회지 Vol.9 No.1

Localized amyloidosis of the bladder is an uncommon disease. As it can be mistaken as a malignant disease, urinary bladder neoplasms should be included as differential diagnosis. And systemic amyloidosis also should be considered because the prognosis of localized amyloidosis is very different from that of systemic amyoidosis. The primary treatment for localized amyloidosis of the bladder is transurethral resection of the mass. And annual cystoscopic evaluation is recommended to detect recurrence. In the current case, the patient underwent transurethral resection of bladder mass twice for 2 years, and supposed to be recurred amyloidosis due to proliferation of residual amyloid. Because localized amylodosis of bladder can be recurred, long-term follow-up is needed after complete resection of the mass.