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Park, Dasom,Park, Jong-Hyun Korean Society of Food Science and Technology 2019 한국식품과학회지 Vol.51 No.6
To control pathogenic E. coli in biofilm, bacteriophages were isolated from environmental samples. Seventeen isolates had depolymerase activities by translucent zones at the rims of plaques. To determine biofilm-forming ability, an abiotic plastic surface of polystyrene was used; E. coli O103 showed the highest biofilm formation at 30℃ after 24 h. Moreover, biofilm by E. coli O103 on the biotic surface of lettuce was observed by a scanning electron microscope. The bacteriophage cocktail of ΦNOECP40 and ΦNOECP44 showing depolymerase activities was prepared to eliminate the E. coli inbiofilm. By organic acids, reduction of E. coli in biofilm was insignificant and almost undetectable. However, the abundance of E. coli in biofilm was reduced by 3 log CFU/mL from 7.3 log CFU/mL after 60 min with the bacteriophage cocktail. Therefore, we suggest that bacteriophages with depolymerase could be utilized to effectively control pathogenic E. coli in biofilm.
Dasom Park,Aqoma, Havid,Ilhwan Ryu,Sanggyu Yim,Sung-Yeon Jang IEEE 2016 IEEE journal of selected topics in quantum electro Vol.22 No.1
<P>Colloidal quantum-dot-based photovoltaic devices (CQDPVs) were fabricated at room temperature in air atmosphere via a spraying technique. Lead sulfide colloidal quantum dots (CQDs) were utilized for this process and various fabrication conditions such as the spraying pressure, types of ligand molecules, duration of ligand exchange, and the band-gap of the CQDs were investigated in order to optimize the device performance. The power conversion efficiency reached 4.00% (V-OC of 0.57V, J(SC) of 11.79 mA center dot cm(-2), and FF of 0.60) when similar to 145 nm thick sprayed CQD layers were utilized; this value is comparable to that achieved with the conventional spin-coated devices. The generality of the conditions used for fabrication of the sprayed CQDPVs was demonstrated in the fabrication of various CQDs having different band-gaps (1.34-1.61 eV). This technique provides an avenue for the application of a high-throughput process for CQDPV fabrication. Because the materials used herein for device fabrication are not completely optimized, there is further scope for improving device performance.</P>
Park, Dasom,Yim, Sanggyu Elsevier 2020 Solar energy materials and solar cells Vol.208 No.-
<P><B>Abstract</B></P> <P>Efficient energy band alignment of heterojunction layers in colloidal quantum dot (CQD)-based solar cells is a crucial factor to govern the charge transport characteristics and device performance. In this work, we develop novel cascaded-junctions of lead sulfide (PbS) CQD triple layers consisting of an alkylammonium iodide (AMI)-treated PbS bilayer and a 1,3-propanedithiol (PDT)-treated single layer. The two AMIs, <I>i.e.</I> triethylamine hydroiodide (tri-EAHI) and tetraethylammonium iodide (TEAI), are less hindered and have superior passivation performance compared to tetrabutylammonium iodide (TBAI), the most commonly used AMI. In addition, the band positions of the PbS-TEAI and PbS-tri-EAHI layers are deeper by 0.26 and 0.46 eV, respectively, than those of the PbS-PDT layer, and hence the sequential stacking of these three layers enable an effective cascaded band alignment. The various benefits of the improved band alignment such as increased built-in potential, reduced trap states, widened depletion region, enhanced charge transport and suppressed charge recombination lead to a significant improvement in the device parameters, and the best power conversion efficiency of 10.46% is obtained for the cascaded PbS-tri-EAHI/PbS-TEAI/PbS-PDT-based device.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Cascaded-junctions of PbS CQD layers was obtained using three different ligands. </LI> <LI> Efficient band alignment improved charge transport and suppressed recombination. </LI> <LI> A power conversion efficiency reached 10.46% for the cascaded-junction solar cell. </LI> </UL> </P>
Park, Hyelim,Park, Hyewon,Mun, Dasom,Kim, Michael,Pak, Hui-Nam,Lee, Moon-Hyoung,Joung, Boyoung Elsevier 2018 Heart rhythm Vol.15 No.5
<P><B>Background</B></P> <P>Left stellectomy has become an important therapeutic option for patients with potentially fatal arrhythmias. However, the antiarrhythmic mechanism of left stellectomy is not well known. The cholinergic anti-inflammatory pathway (CAIP) is a complex immune mechanism that regulates peripheral inflammatory responses.</P> <P><B>Objective</B></P> <P>The purpose of this study was to evaluate the effect of left stellectomy on CAIP using rat experimental autoimmune myocarditis (EAM) models.</P> <P><B>Methods</B></P> <P>EAM was produced by injecting 2 mg of porcine cardiac myosin into the footpads of rats. Left stellectomy was performed before EAM induction. We evaluated the effect of left stellectomy on arrhythmic events, survival, inflammation, and CAIP in rats without and with EAM.</P> <P><B>Results</B></P> <P>Left stellectomy prevented arrhythmia and improved survival in EAM rats. Left stellectomy decreased the levels of tumor necrosis factor α, interleukin 6, and high mobility group box 1 (<I>P</I> < .05 vs EAM) in serum and heart tissues from EAM rats. In heart rate variability analysis, high-frequency peaks of the power spectrum densities, reflecting parasympathetic cardiovagal tone, were significantly decreased in EAM rats, but increased after left stellectomy. The ratios of phosphorylated STAT3/STAT3 (signal transducer and activator of transcription 3) and phosphorylated JAK2/JAK2 (Janus kinase 2) decreased in cell lysates of the spleen, liver, and heart in EAM rats. However, the same ratios significantly increased after left stellectomy. Nuclear factor κB in cell lysates of the spleen, liver, and heart increased in EAM rats, but decreased after left stellectomy.</P> <P><B>Conclusion</B></P> <P>In EAM models, left stellectomy increased survival of the rats while showing antiarrhythmic effects with reduced inflammation via activation of the JAK2-STAT3–mediated signaling cascade. Our findings suggest an exciting opportunity to develop new and novel therapeutics to attenuate cardiac inflammation.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Dasom Park,Jong-Hyun Park 한국식품과학회 2019 한국식품과학회지 Vol.51 No.6
To control pathogenic E. coli in biofilm, bacteriophages were isolated from environmental samples. Seventeen isolates had depolymerase activities by translucent zones at the rims of plaques. To determine biofilm-forming ability, an abiotic plastic surface of polystyrene was used; E. coli O103 showed the highest biofilm formation at 30oC after 24 h. Moreover, biofilm by E. coli O103 on the biotic surface of lettuce was observed by a scanning electron microscope. The bacteriophage cocktail of ΦNOECP40 and ΦNOECP44 showing depolymerase activities was prepared to eliminate the E. coli inbiofilm. By organic acids, reduction of E. coli in biofilm was insignificant and almost undetectable. However, the abundance of E. coli in biofilm was reduced by 3 log CFU/mL from 7.3 log CFU/mL after 60 min with the bacteriophage cocktail. Therefore, we suggest that bacteriophages with depolymerase could be utilized to effectively control pathogenic E. coli in biofilm.