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Hepatic Scintiangiography Using Gamma Camera System
Kim, Choon Yul,Bahk, Yong Whee,Yoon, Sae Chul CATHOLIC MEDICAL CENTER 1979 Bulletin of the Clinical Research Institute Vol.7 No.1
The hepatic seintiangiography plus static liver imaging using gamma camera system is very new diagnostic technique and proved effective in diagnosing hepatoma, metastasis and liver abscess. The finding is able to use as an aid in differential diagnosis of space-occupying lesions of the liver. This test is therefore absolutely useful in differentiating abscess or cyst from neoplastic condition of the liver.
Clinical Results of Radiofrequency Hyperthermia Combined with Radiation
Kim, Choon-Yul,Choi, Ihl Bohng,Chung, Su Mi,Bahk, Yong Whee CATHOLIC MEDICAL CENTER 1991 Bulletin of the Clinical Research Institute Vol.19 No.2
Clinical results of radiothermotherapy applied to 45 tumors were reported. Hyperthermia was given regionally with an radiofrequency capacitive heating device using 8 MHz (Cancermia, GHT-RF8, Green Cross CO. Seoul, Korea). Hyperthermia was given twice weekly immediately after irradiation. Intratumor temperature of 40℃ to 44℃ were maintained for 45 to 60 minutes. Radiation doses varied from 15 Gy to 72 Gy. Of the 45 tumors treated, 8 (18%) showed CR, 4 (9%) PRa and 23 (51%) PRb. Ten (22%) tumors showed NR. Tumor response was greatly dependent on the intratumor temperature. Most complete regression was observed in high intratumoral temperature group. Tumor response correlated with tumor size and depth that tumor located in also, but not with heat sessions and histologic features. Our clinical results suggested that radiofrequency hyperthermia combined with radiation has a therapeutic advantages in the treatment of cancers.
Kim, Choon Yul,Oh, Yoon Kyeong,Bahk, Yong Whee CATHOLIC MEDICAL CENTER 1986 Bulletin of the Clinical Research Institute Vol.14 No.1
The effects of local hyperthermia using 2,450 MHz microwave on normal skin, subcutaneous adipose tissue, and superficial skeletal muscle of mouse were investigated. The heat was applied to the right thigh of mouse by using 2,450 MHz microwave technique. All thermal exposures lasted for 30 minutes once the selected temperatures were reached. The local temperatures achieved were 38℃, 43℃, and 46℃, respectively. Samples of tissues heated by above methods were obtained at 3, 12, and 24 hours after heating. Then all samples were fixed in 10% formalin solution and stained with hematoxylin-eosin and Masson's trichrome. The experimental results were as follows: 1. At 24 hours after heating at 38℃ for 30 minutes, capillaries showed dilatation and congestion. 2. At 3 hours after heating at 43℃ for 30 minutes, marked dilatation and congestion of capillaries and degenerative change of dermal collagen and myocytes were demonstrated. Atrophy of epidermis, hyaline thrombus formation of capillaries, and necrotic myocytes were also seen at 12 hours after 43℃ heating. At 24 hours after 43℃ heating, desquamation of epidermis and necrosis of subcutaneous adipose tissue and superficial skeletal muscle were noted. 3. At 3 and 12 hours after heating at 46℃ for 30 minutes, atrophy and desquamation of epidermis, degeneration of dermal collagen, marked dilatation and congestion of capillaries, and necrosis of subcutaneous adipose: tissue and superficial skeletal muscle were seen. Hyaline thrombus formation of a few capillaries was also seen in 24 hours after 46℃ heating. These results suggest that skin, subcutaneous adipose tissue, and superficial skeletal muscle can be damaged by 2,450 MHz microwave hyperthermia in the temperature range of 43℃ to 46℃.