Antiangiogenic-Like Properties of Fermented Extracts of Ayurvedic Medicinal Plants

Che´rif Rabhi,Guillaume Arcile,Le´on Cariel,Christine Lenoir,Je´rome Bignon,Joanna Wdzieczak-Bakala,Jamal Ouazzani 한국식품영양과학회 2015 Journal of medicinal food Vol.18 No.9

The three ayurvedic medicinal plants, Withania somnifera, Emblica officinalis, and Bacopa monnieri, were extracted by high-pressure static extraction using the Zippertex® technology. The extracts were mixed to reach quantifiable amounts of active compounds identified by high-pressure liquid chromatography-mass spectrometry (HPLC-MS) analysis. The mixture of extracts was incubated with resting cells of the fungus Beauveria bassiana ATCC 7159. The fermentation promoted the fluidization of the starting dense mixture, while HPLC monitoring evidenced the disappearance of glucogallin from E. officinalis extract and the concomitant increase in gallic acid content. Topical exposure of the chick embryo chorioallantoic membrane (CAM) to the nonfermented extract led to the extensive necrosis and destruction of the treated membrane. However, the fermented extract was shown to be free of any toxicity. Furthermore, compared with the untreated CAM, the fermented sample reduced CAM vascularization, suggesting its antiangiogenic potency. The innocuity of the fermented extract was demonstrated using the in vivo LD50 test, the morphological examination of internal organs of treated rats, as well as the evaluation of blood biomarkers of liver damage (aspartate aminotransferase and alanine aminotransferase). The fermented extract was developed as a nutraceutical antiangiogenic treatment of age-related macular degeneration and commercialized in an oral form named Ethnodyne-Visio™.

제주 우수 육상경기 선수들의 년중 훈련효과 분석 및 처방

김철원,임상용,김승곤,오만원,김성찬,이창준,남사웅,이세형,류재청 濟州大學敎 體育科學硏究所 1996 체육과학연구 Vol.2 No.-

The study was undertaken to analysis, evaluate, and prescribe t h e annual effect of training of periodically anaerobic and aerobic motor ability for Che-Ju representive team of elementary, middle and high school athletes. first. the performance can be obtained when it was prescribed proper training after analysis of physical fitness by each events. second, individually fitness. scientific analysis. prescription. proper management of athlete will be necessary to apply. In addition to physiology aspect, it is essential to consider sport biomechanics. sport psychology when we prescribe specific events and necessary approach in demension coach-athlete-researcher for individual.

제주 우수 수영 선수들의 년중 훈련효과 분석 및 처방

김철원,임상용,김승곤,오만원,김성찬,이창준,남사웅,이세형,류재청 濟州大學敎 體育科學硏究所 1996 체육과학연구 Vol.2 No.-

The study was undertaken to analysis, evaluate, and prescribe the annual effect of training of periodically anaerobic and erobic motor ability for Che-Ju representive team of elementary, middle and high school athletes, first the performance can be obtained when it was prescribed proper training after analysis of physical fitness by each events, second individually fitness scientific analysis. prescription. proper management of athlete will be necessary to apply.

의료소비자의 관계혜태 지각이 관계의 질 및 행동의도에 미치는 영향

허철선(Che이-Seon Heo),유광우(Kwang-Woo Yoo) 한국무역연구원 2014 무역연구 Vol.10 No.1

Medical institutions are important to develop and maintain enduring relationship with medical service conswners. So, this research aims to find out the effect of medical service conswners perception of relational benefits on relationship quality and behavioral intention. On the basis of the literature review, the research model is established. This research has been done through the survey utilizing medical service consumers in Gangwondo, and the effective 368 questionnaires are tested for the research model. The main findings are as follows. First, among 5 key dimensions of relational benefits, psychological, customization, economic, and information benefits except social benefits have significant effects on relationship satisfaction. Also, medical institutions type and medical service consumers type as moderating variables are included concurrently, and the significant differences are found in other 4 benefits except relationship between social benefits and relationship satisfaction. Second, relationship satisfaction relates positively to relationship commitment and behavioral intention. But the normative commitment, one of 3 key dimensions of relationship commitment, has no significant effects on recommendation to others. Third, the revisit intention has significant effect on recommendation to others. Finally, the findings reveal that the overall goodness fit index of the model is comparatively good and model set in this research is significant. At the end of the research, managerial implications, limitations and future research directions are suggested.

의료 화상을 위한 전처리 필터들의 특성에 관한 연구

강명아,최종주,정종필,정채영,정남채 조선대학교 기초과학연구소 1997 自然科學硏究 Vol.20 No.1

There has been no fixed rule of pre-processing course required to do image processing that it was barely possible to find the proper pre-processing course, only to process with experience till now. In this paper, lots of application method of pre-processing algorithm, only available by the non-typified and experiential method, shall quantify and the algorithm method of algorithm according to the rule shall calculate the frequency of the value of each pixel gray level and the histogrm of the image. And then average it to all pixel number and finally set a high-ranking or optional % standardized by the average value in teh standard value. The result of a experiment showed the Median filter is superior to the Mean filter in all image of the smoothing filter. The sobel filter extracted feature. The laplacian filter presented sectional feature which not showed in original image.

퍼망간네이트-옥살산에 의한 아크릴아마이드 수용성중합에서의 첨가제 효과

이채주,이종광 慶尙大學校 1986 論文集 Vol.25 No.2

The polymerization of Acrylamide initiated by MnO4-H2C2O4 redox pair has been studied in aqueous media at 35±0.2℃ in nitrogen armosphere. The rate of polymerization is independent of activator concentration (2×10-3 to 4.5×10-3 mole/1) expect at very high (above 6.3×10-3 mole/1) concentration. The initial rate of polymerization has been found to be proportional to nearly 1.17 power of low catalyst concentration (2.3×10-4 to 6.25×10-4 mole/1) and nearly the first power of low monomer concentration (1.47×10-3 to 3.3×10-3 mole/1). The overall energy of activation has been found to be 10.99kcal/mole within the temperature range 30-50℃. The effects of various additives have been studied. Organic solvents and salts depress the initial rate but small amounts of manganous salts(MnSO4, MnCl2) increase the initial rate to a considerable extent. A complexing agent(NaF) and anionic and cationic surfactants show marked influence on the rate of polymerization. The intrinsic viscosity in aqueous acrylamide solution at 30±0.1℃ was 1.01 and the molecular weight of the polyacrylamide was 63,900.

숙련자와 미숙련자의 배드민턴 스매시 동작의 운동학적 비교 분석

류재청,김익상 한국운동역학회 2003 한국운동역학회지 Vol.13 No.2

Ryew, C-C and Kim, I-S. Kinematic Analysis of Badminton Smashing Between the Skilled and the Unskilled. Korean Journal of Sport Biomechanics, Vol. 13, No. 2, pp. 139-160. The purpose of this study was to suggest the guideline for scientific and quantitative skill acquisition methods of badminton smashing so that the novice could learn the motions of badminton smashing efficiently. The subject participated consisted of total 6 middle school students of the skilled(3) and the unskilled(3). The cinematographical experimental & Analysis equipments used in the study were composed of two Model D-5100 Video Cameras, a control point, a synchronization timer and Kwon3d motion analysis system. The conclusions obtained were as follows; 1. It was necessary for the unskilled to learn the smashing impact phase in situation of max. Velocity of COG in order to minimize the timing loss phase. 2. Particularly, The power from segments of Power Zone must participate in utilization in sequence of order of trunk-upper arm-forearm-hand-racket segment in both the skilled and the unskilled. 3. Therefore It was necessary for the unskilled to do smashing practice for cumulated sum of absolute & relative velocity transfer into shuttle cock after adjusting anterior-posterior tilting angle and max timing, in sequence of segment recruited.

박물관 관람자의 동선특성에 관한 조사

임채진,한선영 홍익대학교 산업디자인 연구소 1999 미술디자인 논문집 Vol.- No.4

The purpose of this study is to analyze the characteristics of exhibition circulation through the movement pattern. It looks into the factors under the influence with the visitor's movement. The method of analysis is statistics of investigation by following after visitors. The viewing behavioral of exhibition based on the time, speed, proportion of appreciation is classified into three types of the profound, the general, the passing viewers. The characteristics of the viewing form of these patterns largely depend on the space elements which are the structure form. And particularly the position of exit, the width of exhibition space and the connection of exhibition space stand out the disparity of the factor of the spatial structure. These three patterns bring about a lot of encounter in the exhibition space according to the difference of these routes consequently. So appropriate to the planning of each pattern can offer visitors to more effective environment of exhibition.

Heinrich Heine 詩論 : 特히 "Neue Gedichte"를 中心으로

轉在弘 釜山大學校 師範大學 1978 교사교육연구 Vol.5 No.1

Welch ein Lied! "Eine gewaltige Lust ergreift mich! Wa˝hrend ich sitze, und schreibe, erklingt Musik unter meinem Fenster, und an dem elegischen Grimm der lang-gezogenen Melodie, erkenne ich jene Marseiller Hymne, womit der scho˝ne Barbaroux und seine Gefa˝hrten die. Stadt Paris begru˝Bten, jener Kuhreigen der Freiheit, bei dessen To˝nen die Schweizer in den Tuilerien das Heimweh bekamen, jener triumphierende Todesgesang der Gironde, das alte su˝Be Wiegenlied-Es durehschauert mich mit Feuer und Freude, und entzU˝ndet in mir die glU˝henden Sterne der Begeisterung und die Raketen des Spottes. Ja, diese sollen nicht fehlen, bei dem groBen Feuerwerk der Zeit. Klingende Frammenstro˝me des Gesanges sollen sich ergieBen von der Ho˝he der Freiheitslust, in ku˝hnen Kaskaden, wie sich der Ganges herabstU˝rzt vom Himalaya! Und du, holde Satyra, Tochter der gerechten Themis und des bocksfu˝Bigen Pan, leih mir deine Hu˝lfe, Du bist ja mu˝tterlicher Seite dem Titanengeschlechte entsprossen, und hassest gleich mir die Feinde deiner Sippschaft, die schwa˝chlichen Usurpatoren des Olymps. Leih mir das Schwert deiner Mutter. damit ich sie richte, die verhaBte Brut, und gib mir die Picke-lflo˝te deines Vaters, damit ich sie zu Tode pfeife-">>schrieb Heinrich Heine die Spa˝tere Nachschrift der'〉Reisebilder'<<schon im November 1830. Nachdem Heine den Reisestoff auf die beschriebene Weise aufgearbeitet hatte, war er in politischer Hinsicht fu˝r ihn abgeschlossen. Heines Bedu˝rfnis nach Variation lieB eine einfache Wiederholung nicht zu. So arbeitete er mit neuem Stil das>'Neuer Fru˝hling'<1828/31von der Neuen Gedichte in Hamburg auf. Die Chance fu˝r eine. Realisierung ist hier gro˝Ber. In dieser Phase ist ihm die politisch-gesellschaftliche Aufgabe wichtiger als die dichterische. Denn Heine mo˝chte als politischer Befreier in die Geschichte eingehen. Auch an seinen Werk Neuer Fru˝hling<' wendet sich das Technische von Metrik, Sprache und Form.

Heinrich Heine의 Realismus에 關한 考察

韓在弘 釜山大學校 師範大學 1975 교사교육연구 Vol.2 No.1

Bei Heine erscheint das Zeigen des Auswegs gegen den Feudalismus konkret; es ist, wie die Volksbewegung den Menschen weckt, sein Geistleben aufbluhen laBt, ihm kraft und Liebe verleiht. Bei keinem seiner Zeitgenossen ist die Emporung gegen das Alte so mitreiBend, das Pathos des Neuen so begeisternd wie bei Heine. In dieser Frage der Verteidigung zertretener Menschenwiirde, der Verteidignng des verhinderten Menschseins ist Heinrich Heine radikaler und entschlossener als Wolfgang von Goethe. Auch diese konnen bei Heine eine groBe Rolle spielen; entscheidend ist die objektive Fortsetzung der groBten humanistischen Probleme der bisherigen Menschheitsentwicklung. Heine sucht nun die HarmOnie des Menschen und die ihr entsprechende Schonheit in der Kunst. Sdnst wirken die groBen Dichter, wie Goethe, der klassisehen Periode Deuts- chlands bereits nach der Franzosischen Revolution und haben deshalb die heroischen Illusion der Aufkl'arung verloren. Heine bietet dem Menschen eine starke Waffe im Kampf gegen das primitive Privileg- iensystem des Feudalismus und scharfe Waffen fur den Kampf gegen den Feudalismus und die absolute Monarchie an. Mit sturmischem Enthusiasmus und seiner genialen Fahigkeiten arbeitet Heine fiir die Befreiung aus Feudalismus; das heiBt: ich versuchte es, wie in Frankreich Julirevolution und in Deutschland Hambachfest Heinrich Heine verzieren.