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      • Acoustic Cues to the Perception of the Place of Articulation in English Stops

        Ahn, Mee-Jin 배재대학교 인문과학연구소 2005 人文論叢 Vol.22 No.-

        이 논문은 영어 파열음의 위치자질을 인식하는데 필요한 음향 단서에 관한 연구이다. 실험의 결과는 페쇄단계, 파열, 기식음, 포만트 추이 각각 모두가 파열음의 위치자질에 대한 음향 단서임을 보여주고, 특히 이 인지 실험은 위치동화 등의 음운현상에 나타난 CV와 VC의 비대칭 현상도 설명해 준다. 그러나 무성파열음의 경우, 폐쇄나 파열, 기식 등의 단서를 제외하고 모음 부분만을 들려주었을 때에는 위치자질을 인식하는데 CV와 VC의 비대칭은 나타나지 않음을 보여준다. 또한 경구개 파열음의 위치자질의 인식에 있어서는 순음이나 치경음보다 파열 단서에 더 많이 의존한다는 결과를 나타낸다.

      • 혈당측정기 GlucoDr™ System의 평가

        박철영,류미숙,우정택,김성운,김진우,김영설,안규정 대한당뇨병학회 2002 임상당뇨병 Vol.3 No.2

        연구배경: 당뇨병 환자에서 엄격한 혈당조절은 환자의 예후와 밀접한 관련이 있다. 혈당조절을 철저히 하기 위해서는 자가 혈당 측정기의 사용이 필수적이라 할 수 있다. 또한 저혈당이 빈번하게 발생하거나, 위험요소가 있는 환자들에게도 유용하게 사용될 수 있다. 이에 저자들은 전기화학감지법의 원리를 이용하여 국내에서 처음 생산된 자가혈당측정기인 GlucoDr™ blood Glucose Testing System(ALL Medicus, Co, Korea)를 현재 국내에서 시판되고 있는 다른 제품과 비교, 평가하여 임상적 유용성을 살펴보고자 하였다 방법: 혈당측정기준장비는 YSI 2300 STAT Plus(YSI Incorporated, USA)를 사용하였으며 GlucoDr™외에 Glucocard(KDK, Japan), Precision QID(Abbott Laboratories, Co, USA), Glucotrend(Roche, USA), Surestep(Lifescan, USA)의 다른 혈당측정기를 같이 평가하였다. 정밀도, 직선성, 비교방법과의 상관관계 평가, 검체량에 따른 영향, 헤마토크리트에 따른 영향, 검사자에 따른 영향, 항응고제에 따른 영향들을 평가하였다. 결과: 본 연구에서의 주된 평가대상인 GlucoDr™의 평가결과, 정밀도를 나타내는 검사 내, 검사 간 변이계수는 8%이내였으며, 45~500mg/dL 범위에서 R²=0.9906, 0.9984 정도의 직선성을 나타내었다. 본 연구에 있어 비교방법으로 이용한 YSI 2300 STAT Plus와의 상관관계 및 정확도는 y = 1.0058x + 0.453, R = 0.9853인 것으로 나타났다. 검체량이나 검사자 및 항응고제에 따른 측정값에는 유의할만한 차이가 없는 것으로 나타났으나, 헤마토크리트가 증가 또는 감소함에 따라 최소 10%에서 최대 26% 가량의 영향을 받는 것으로 관찰되었다. 결론: GlucoDrTM는 국내 사용되는 다른 혈당측정기와 비교하여 유용할 것으로 생각된다. Background: Self-monitoing blood glucose devices are sidely used in monitoring and point-of-care testing for the management of diabetic patients. We performed the present study to evaluate the performance of the GlucoDr™ blood glucose testing system using an electrochemical technique. Method: The GlucoDr™ was evaluated for linearity, precision, comparison of method, the effect of sample volume, hematocrit concentration, reapplication, operator and application methods. Results: The GlucoDr™ showed good linearity for glucose concentrations ranging from 52mg/dl to 475mg/dl(r²=0.971). The single day, and day-to-day, CV were within 8%. Excellent correlation was found between the GlucoDr™ and YSI 2300 STAT Plus(y=1.0058x + 0.453, r²=0.9710). The sample volume, reapplication, operator and application method produced no significant effect on the test result. An overestimation in the glucose values was found with low hematocrit concentrations. There was no significant effect by the anticoagulants, with the exception of citrate. Conclusion: The GlucoDr™ showed good linearity, precision and correlation with the reference method and provided rapid and reliable result for blood glucose levels. Therefore, the GlucoDr™ seems appropriate for clinical use in the management of diabetic patients.

      • 부신 결핵에 의한 Addison씨병 1예

        송치운,구본정,안봉수,전준식,안미애,이진홍,송민호,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2

        Addison's disease is a rare primary adrenal insufficient disorder resulting from chronic deficiency of adrenal cortical hormones. Clinical manefestations are generalized weakenss, weight loss, hyperpigmentation (especially sun exposed area and mucous membrane), hypotension, hyponatremia, hyperkalemia, gastrointestinal symptoms (involving anorexia, nausea, vomiting, abdominal pain). A 34-year-old woman has experienced slowly progressive generalized weakenss and skin pigmentation, anorexia, nausea, vomiting with ascites and diffuse abdominal pain. On the time of admission, her main clinical manifestations were anorexia, nausea, vomiting, fatigue, generalized weakness, amenorrhea, hair loss, diffuse abdominal pain revealed as Addison's disease due to bilateral adrenal tuberculosis. Her adrenal insufficient symptoms were recovered with the replacement of adrenocortical hormones and antituberculous medications. After treatment, Her skin pigmentation was decreased and menstruation was reappeared. Here we experienced one cases of Addison's disease with tuberculous peritonitis.

      • 혈액투석중인 만성신부전 환자에서 골대사 지표로써의 Osteocalcin치

        송치운,이진홍,안미애,윤환중,윤상임,성기양,이강현,송민호,이강욱,신영태,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

        Background : Serum osteocalcin is synthesized by osteoblast and has been shown to be sensitive indicator of bone turnover inpatients with various metabolic bone disease. In renal osteodystrophy, serum osteocalcin is elevated due to decreased renal clearance and elevated level of PTH. This study was done to evaluate the usefulness of serum osteocalcin as a marker of bone metabolism and the correlation with other biochemical markers of bone metabolism. Methods : We measured serum osteocalcin, calcium, phosphorus, ALP(alkaline phosphatase) and PTH(parathyroid hormone) in 37 patients with end stage renal disease on hemodialysis. Osteocalcin was determined by radioimmunoassay and PTH was determined by radioimmunometric assay. Results : 1) The mean level of serum osteocalcin in ESRD patients was 233.8± 218.2ng/ml which was significantly higher than that of controls(p<0.0001). 2) The mean level of serum PTH in ESRD patients was 40.5± 43.8pg/ml was significantly higher than that of controls(p<0.005). 3) There was a significant positive correlation between the level of serum PTH, ALP and the level of serum osteocalcin in ESRD patients. 4) By using multiple regression, PTH is most reliable factor that affect to elevated level of serum osteocalcin ( beta coefficient = 0.687, Sig T<0.05). Conclusion : Serum osteocalcin as a marker of bone metabolism in ESRD patients is more useful than other biochemical marker such as serum calcium, phosphorus, ALP and PTH is a most reliable factor that affect to elevated level of serum osteocalin.

      • 당뇨병환자에서 게이트심장혈액풀신티그라피를 이용한 심기능 평가

        윤상임,송치운,이진홍,안미애,성기양,송민호,이강욱,신영태,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

        Major cardiovascular complications of diabetes are coronary atherosclerosis, diabetic dilated cardiomyopathy, autonomic neuropathy and those are major causes of morbidity and mortality in diabetic patients. Gated blood pool heart scan is noninvasive and useful method for evaluation of functional status of heart in diabetics. We evaluated 52 patients with diabetes and divided 3 groups. Group 1 were 11 patients without proteinuria or with proteinuria less than 550mng during 24 hours. Group 2 were 9 patients with proteinuria more than 550mg during 24 hours and group 3 were 32 patients with endstage renal diasese due to diabetes. We performed 99mTc-HSA cardiac gated blood pool scan and used left ventricular ejection fraction(LVEF), peak ejection rate(PEF) to indices of LV systolic function and peak filling rate(PER) to index of LV diastolic function. The results were follows : 1) LVEF, PER were significantly lower in diabetics with ESRD than diabetics without ESRD, but there were no significant difference between normal controls and diabetics without ESRD 2) PFR was significantly lower in diabetics than normal controls, but there were no significant differences in diabetics with or without nephropathy. 3) There were negative correlation between PER, PFR and duration of diabetes. On the basis of results, PFR is a LV functional index of GBPS which can disclose early change of LV dysfunction in patients with diabetes.

      • 폐경기후 골다공증의 약물요법

        노흥규,송치운,이진홍,안미애,송민호 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

        Postmenopausal osteoporosis is an enormous public health problem. Estrogens, and various drugs were developed and used for prevention and treatment of postmenopausal bone loss. In this study, We evaluated the effects of cycloprogynova, cyclofenil and ipriflavone on postmenopausal bone loss. Fourty post menopausal women were divided into 3 groups by treatment modalities Cyclofenil group (groupl), Cycloprogynova group(group 2) and Ipriflavone group(group 3). Basal bone mineral densities in all subjects were determined by DEXA(Dual Energy X-ray Absorptiometry) and those were compared with bone mineral densities after medication. The durations of medication in all groups were showed no statistical difference, group 1 11.4 ± 3.4 months, group 2 10.6 ± 3.9 months, group 3 12.9 ± 3.4 months. The patients of group 2 showed significant increase in bone mineral densities and the patients of group 1 and group 3 revealed no significant bone loss on paired T-test. Comparing with rates of bone loss in normal Korean postmenopausal women, the rates of bone loss in all subjects were effectively retarded. The significant bone loss (above longterm intertest coeffcient of variation) was noted in 8 patients out of 23 subjects in group 1, in 9 patietns out of 11 subjects in group 2 and in 2 patients out of 6 subjects in group 3. In conclusion, estrogen/progesteron(Cycloprogynova) replacemnt therapy showed most prominent bone preserving effect and Cyclofenil and Ipriflavone also effectively delays shorterm bone loss in postmenopausal women.

      • KCI등재

        Perception and Production of English Vowels [ɔ] and [o] by Korean Learners of English

        Ahn, Mee-Jin(안미진) 새한영어영문학회 2014 새한영어영문학 Vol.56 No.4

        This paper examines how Korean learners of English perceive and produce the English vowels [?] and [o] through vowel identification tests. According to the results of the perception and the production tests, Koreans showed higher accuracy rates in perception than in production of [?] and [o]; Group A with relatively high English proficiency performed better than Group B with relatively low English proficiency in the perception test, but not in the production test; Group B consistently showed higher accuracy in the perception and production tests of [o] than in the same tests of [?]; and the syllable structure of target words also affected the accuracy rates in the perception and production tests and its effects were the same in both tests. The results support Flege et al.’s (1997) claims that the perception precedes the production; and that the performance in perception is correlated to that in production.

      • KCI등재

        The Korean /n/-insertion before [j] as [nasal] insertion

        Mee-Jin Ahn 한국음운론학회 2008 음성·음운·형태론 연구 Vol.14 No.3

        this paper argues that the Korean /n/-insertion before glide [j] is a consequence of feature [nasal] insertion to avoid a heterornorphemic consonant and glide [j] sequence in syllavle initial position. The /n/-insertion is not to remedy a hetrosyllbic C.Y sequence, as asserted in previous approaches (Kim-Renaud 1974, Ahn 1985, Park 2005, Lee 2004, Oh 2006, Lee and Lee 2007, etc.). I argue that the /n/-insertion is irrelevant to the Syllavle Contact Law, by which two heterosyllabic vonsonants should go from high to low in sonority. I rather claim that the Korean /n/-insertion occurs to avoid tautosyllabic and heteromorphemic CY sequences, which are not permitted in Korean. Also, I claim that the /n/-insertion is not a segment insertion but a feature insertion. The insertion of feature [nasal]is the most faithful way to fix the marked heteromorphemic CY structure: a feature insertion is more faithful than any segment insertion; feature-filling is more faithful than feature-changing. Also, the output form of the feature [nasal] insertion performs double functions; it makes a morpheme boundary coincide with a syllable boundary and breaks the illegitimate sequence. Thus, the [nasal] insertion is the most optimal way to prevent the illegitimate sequence heteromorphemic CY in Korean.

      • KCI등재

        TWO DISTINCT PATTERNS OF KOREAN /n/-INSERTION

        MEE-JIN AHN 사단법인 한국언어학회 2009 언어학 Vol.0 No.54

        This paper argues that Korean /n/-insertion appears as a unitary process, but it comprises two distinct processes: /n/-insertion before /i/ and /n/-insertion before /j/. The apparent /n/-insertion before /i/ is not a synchronic /n/-insertion at all. Rather it is an epiphenomenon of the /n/-O alternation due to the historical wordinitial /n/-deletion and lexicalization of words that lost their initial /n/. On the other hand, the /n/-insertion before /j/ is not a peculiar segment /n/-insertion but a feature [nasal]-insertion, which is a synchronically productive process to remedy a marked heteromorphemic CY onset cluster. This binary approach accounts for why the /n/-insertion before /i/ is not productive and observed in a few restricted words, and why the /n/-deletion before /j/ is productive and applies to both words with and without etymological /n/.

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