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      • 이 나라의 원자로 - 1955년에 본 우리나라 원자력계의 전망 -

        완영 한국원자력산업회의 1987 원자력산업 Vol.7 No.2

        본고는 우리나라에서 원자력이 태동되던 시절에 미국 북캘로라이나대학에서, 원자력을 연구하던 전완영박사가 1955년 12월 12일자 서울신문에 특별기고한 내용으로서 전체발전량중 원자력발전량이 $50\%$를 상회하고 있는 현시점에서 그 당시의 원자력을 둘러싼 정세와 최초의 원자로도입에 관한 배경을 다시 한번 음미해 보는 것도 의의가 클 것으로 사료된다.

      • KCI등재

        분말 제조변수의 조절에 의한 가스 분무 조업의 최적화

        완영,강영환 대한금속재료학회(대한금속학회) 1994 대한금속·재료학회지 Vol.32 No.6

        The optimized condition for preventing metal delivery tube from freezing up during atomization was evaluated by analyzing the experimental data of gas atomizations which were carried out on various conditions. The optimum condition was established by controlling the protrusion length and the temperature of metal delivery tube. It was observed that powder shape is affected by the collision of particles. The probability of collision among particles can be controlled by changing atomization variables such as protrusion length of metal delivery tube, nozzle slit size and the condition of atomizing chamber. So it is possible to control the powder shape by changing the atomizing variables. It was also shown that the average particle size decrease with increasing atomizing pressure.

      • KCI등재후보

        GIS기반 소방취약지 분석관리 서비스 플랫폼 개발

        완영,조광현,조명흠,김정곤,김성재 한국재난정보학회 2015 한국재난정보학회 논문집 Vol.11 No.2

        소방취약지 분석 관리를 위한 공간정보 분석기법을 자동화하고 소방주제도를 갱신 구축하여 온라인으로 탑재하는 서비스 플랫폼 기술을 개발하였다. 그 결과, 플랫폼을 통하여 화재 진압 활동에 필요한 사전 정보가 제공되는 기반이 마련되었다. 이 결과에 향후 소방취약지 활용서비스 연구가 뒷바침되면 화재진압 현장의 골든타임을 감소시킬 수 있다. 소방분야에 적합한 공간분석과 자동화, 손쉬운 서비스 탑재 운영으로 전문적 관리와 서비스 확대 개선에 만족할 만한 기술적 가능성을 확인하였다.

      • 四鹽化炭素 反覆投與 家兎에 對한 NH₄Cl負荷試驗

        申玩永,金箕洪 고려대학교 의과대학 1972 고려대 의대 잡지 Vol.9 No.1

        This study was undertaken to evaluate changes in blood levels of ammonia nitrogen (NG₃-N), CO₂ contents and urea nitrogen(BUN) following NH₄Cl administration on toxic hepatitis of rabbits induced by carbon tetrachloride (CCl₄). Fourty rabbits were devided into 4 groups. Group Ⅰ: One ㎖ of 30% CCl₄ in olive oil was injected subcutaneously 5 times at intervals of 2 days until the 12th experimental day in 14 animals. Two animals thus treated were sacrificed respectively on the 3rd, 6th, 9th, 12th, 15th, 22nd and 29th day. In addition 2 nontreated animals were sacrificed for control. Blood samples were drawn from each of 14 animals prior to CCl₄ injection for the determination of blood NH₃-N, glutamic pyruvic transaminase (GPT), BUN and serum iron. Group Ⅱ: Eight animals were similarly treated with CCl₄ and blood samples were drawn every 3rd day until 15th day, and again on 22nd and 29th for determination of the same. Group Ⅲ: Ammonium chloride tolerance tests were carried out in 8 normal animals and blood samples were drawn for determination of blood levels of NH₃-N, CO₂ contents and BUN before, and at 1/2, 1 1/2, and 2 1/2 hrs. following NH₄Cl administration. Group Ⅳ: Ammonium chloride tloerance tests were done in 8 animals administered with CCl₄, and blood samples were drawn for the same as in group Ⅲ. Results were as follows: 1. Active central necrosis of the hepatic lobules was observed only until the 12th experimental day. This necrotic area was almost completely replaced by regenerated hepatic cells in the 22nd day and repair was complete on the 29th day. 2. Normal blood levels of NH₃-N, GPT and serum iron were respectively 77.4±17.5㎍%, 36.7±7.9 Sigma-Frankel units and 130.3±33.6㎍%. 3. Average blood levels of NH₃-N, GPT and serum iron which were analyzed in 8 animals on every 3rd day after CCl₄ injection, were respectively 147.4㎍%, 259.6 Sigma-Frankel units, 18.9㎎% and 295.8㎍%. After the last CCl₄ injection blood levels of NH₃-N and BUN returned normal at 10 days, serum iron at 17 days but GPT levels were slightly higher than normal even at 17 days. 4. The NH₄Cl tolerance tests conducted in 8 normal animals showed the average blood levels of NH₃-N, CO₂ contents and BUN as follows: prior to, 1/2, 1 1/2, 2 1/2 hr. after NH₄Cl administration. Blood NH₃-N: 70.5, 143, 81, 73.8㎍%; CO₂ contents: 41.4, 38.1, 37.8, 36.8 vol%; BUN: 22.5, 23.6, 25.2, 27.1㎎%. 5. Average blood levels of NH₃-N, CO₂ contents and BUN in 8 animals following NH₄Cl administration on every 3rd day after CCl₄ injection were respectively as follows: prior to, 1/2, 1 1/2, 2 1/2 hr. after NH₄Cl. Blood NH₃-N: 126.6, 203, 137.6, 116㎍%; CO₂ contents: 42.7, 38.4, 38.3, 35.7 vol%; BUN: 19.6, 20.9, 20.8, 21.1㎎%. Blood ammonia levels were most significantly elevated at 1/2hr. after NH₄Cl loading in both CCl₄ treated and control groups, and elevation rates were 60% and 100%, respectively. However, elevated amount showed 76.4㎍% and 72.5㎍%. BUN levels were highest at 2 1/2hr. in both groups and elevation rates were 8% and 22%. Also elevation amount was 2.6㎎% and 4.6㎎%. CO₂ contents were most decreased at 2 1/2hr. in both groups and decrease rates were 16% and 12%, respectively.

      • KCI등재

        다중지능 이론과 교육과정 개발

        완영,김명희 한국교육과정학회 1999 교육과정연구 Vol.17 No.2

        본 논문은 Howard Gardner가 주창한 다중지능 이론을 한국의 학교현장에 적용하기 위한 하나의 방안으로, 초등학교 교육과정의 개발과정과 평가 측면을 중심으로 논의하고 있다. 이 연구의 내용은 크게 두 가지 측면에서 전개되는데, 그 하나는 다중지능 이론에 기초한 교육 과정 개발이며, 다른 하나는 평가에 대한 새로운 접근이다. 교육과정 개발 측면에서는 통합교육과정과 이해를 위한 교수법(Teaching for Understanding)의 연관성을 통해 주제 선정과정과 학습활동의 관계를 제시하고 있다. 다중지능 이론을 적용한 통합교육과정에서의 평가는 교육과정의 학습 목표 분류 방법, 지능별 요소, 학생 평가 준거를 기초로 분석하였다. 이러한 새로운 교육이론 및 과정개발을 통한 투입, 수행과정, 그리고 산출된 연구결과를 토대로 다중지능 이론의 학교교육에 주는 적용가능성 및 교육적 시사점을 논의하였다. The conviction that Howard Gardner's Multiple Intelligences Theory could alleviate the problems infesting Korean education initiated this study. Accordingly, the purposes of the research are to develop curriculum based on Multiple Interlligences Theory, to use new assessment approaches to verify the feasibility of applying the theory in the elementary school and to study its implications to education in Korea. In terms of curriculum development, Fogarty's Tandem Model was selceted to create integrating curriculum. Under the high level theme of "us" the generative theme structure included sub-themes such as "change", "nature", "travel" and "reflections. " A curriculum realted with "Teaching for Understanding" was also developed. In the area of assessment, the study analyzed th eassessment content according to learning goals and instruments for fair assessment. The research was conducted over a three years period, which included activities ranging from currciculum development, implementation, and assessment. Three hundred twenty elementary school students in the first or second grades participated in research, which applied a varity of qualitavie methods including content analysis, in-depth interview, participant observation and video taping. In additon, peer debriefing, member checking, progressive subjectivity and writing reflexive journals were used to validate the research. Research results from teaching activities are as follows. First, in the areas of Lisguistic and Spatial intelligences, students demonstrated enhanced ability of expressing one's emotions as well as main contents and meaning of lessons. Second, in the courses of applying new theories in the field, teachers themselves became teaching research experts. Third, both students and teachers improved self-esteem and were encouraged to develop their potentail. Fourth, Multiple Intelligences classroom provided students and teachers with a greather ability to understand others. Through such results, the research presents a new approach to applying Multiple Interlligences Theory to curriculum development and assessment in Korean elementary school. It goes on to support th conviction that Multiple Intelligences Theory could contribute to eliminating the excessively competitive learning culture plaguing Korea's education and to creating a new school culture in which all students identifies one's own unique ability and strengths and every member of the school community wins.

      • KCI등재

        Phenyldiazenylphenylpicolinamide 유도체들의 방향성탄화수소 수용체의 길항 활성에 대한 연구

        완영,이효성 한국디지털정책학회 2019 디지털융복합연구 Vol.17 No.1

        Aryl hydrocarbon receptor (AhR) is the master regulator of xenobiotics metabolizing enzymes (XMEs). AhR is activated by aryl hydrocarbons upon binding then goes into the cell nucleus and acts as a transcription factor. Despite the role of AhR in human physiology has been investigated for a long while, it is yet to be understood mainly due to the lack of appropriate chemical agents. Furthermore, it has been reported that AhR is related to a wide range of pathogenesis. In addition, recent studies suggest that the study on the development of AhR antagonist may provide a valid therapeutic agent. Some known antagonists in current use are partially agonistic whereas a pure antagonist is still absent. In this study, two phenyl-ring structures of phenyldiazenylphenylpicolinamide has been modified into various structures and evaluated its impact on the AhR antagonistic activity to elucidate the structure-activity relationship. 방향성탄화수소 수용체(Arylhydrocarbon Receptor, AhR)은 리간드에 의해 활성화되어 체내 외래물질의 대사를 조절하는 전사인자다. 생체 내에서 AhR의 생리학적 역할은 오랜 기간 연구되어 왔으나 활성화를 유발하지 않는 길항제를 비롯하여 유효한 화학적 도구가 아직 개발되지 않아 기능 연구가 제한적이다. AhR이 다양한 질병의 발병기전에서 중요한 역할을 수행한다는 것이 보고됨에 따라 약물 표적으로서 유효하다고 판단되나 치료나 예방을 위한 유효한 약물은 아직 개발되지 않았다. 길항제로 알려진 화합물들은 낮은 농도에서는 활성이 있어 연구 목적으로 활용되고 있으나 높은 농도에서는 방향성 탄화수소를 활성화하는 부분적 agonist로 작용한다. 이에 AhR 활성화를 유도하지 않는 순수한 길항제의 개발이 필요하다. 본 연구에서는 이미 알려진 AhR 길항제의 골격인 phenyldiazenylphenylpicolinamide의 세 고리구조 중 두 고리구조에 존재하는 메틸 기들을 변형하여 활성을 평가하는 구조-활성 관계 연구를 통하여 새로운 길항제를 개발하고자 하였다.

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