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채식자와 비채식자에서 동맥경화성 심장질환 위험도 비교연구
홍상인(Sang In Hong),박흥진(Heung Jin Park),곽성진(Seong Jin Kwak),박순희(Soon Hee Park),유해진(Hae Jin Yu),원동준(Dong Jun Won),박정식(Jeong Shik Park),이중건(Choong Keun Lee),안승혜(Seung Hye Ahn),구종수(Jong Soo Koo) 대한내과학회 1996 대한내과학회지 Vol.51 No.1
N/A Objectives: Hyperlipidemia is well-known as one of the major risk factors of atherosclerotic heart disease. Previous reports indicate that reduction of meat and dairy product consumption has reduced development of coronary heart disease. This study was designed to assess prospectively the difference in blood level of various lipids and coronary artery disease risk between vegetarian and non-vegetarian in Korean adults. Methods :100 vegetarians and 82 non-vegetarians were recruited for lipid test including total cholesterol, triglyceride, HDL-cholesterol, Apo A-I and Apo B during annual routine physical examination. Coronary risk and relative risk were analyzed according to the Framingham study data base using computerized calculation with variables including cholesterol, age, sex, blood pressure, smoking history and diabetes. To evaluate the influence of diet to coronary disease risk, 42 vegetarians and 97 non-vegetarians without other coronary risk factors were analyzed same manner, Result: 1) Total cholesterol was significantly lower in vegetarian groups (group A: 161.4mg/d1±6.76, group C: 160.62mg/dl±28.8) compared to non-vegetarians groups(group B: 180.65mg/dl±5.13, group D: 189.05 mg/dl 37.8)(p<0.01). 2) Other lipid values did not show significant difference. 3) Coronary risk was significantly lower in vegetarian groups compared to non-vegetarians(group A : 1.48% vs. group B: 1.78%; group C: 2.0% vs. group D: 6%). 4) Relative risk was also significantly lower in vegetarian groups compared to non-vegetarian groups (group A: 0.75±0.31 vs. group B: 1.00±0.41; group C: 0.74±0.2 vs. group D: 1.09±0.44) Conclusion: This study shows vegetarian group has significantly lower total cholesterol level and reduced coronary heart disease risk compared to non-vegetarian group.
십이지장궤양 환자에서 H . pylori 박멸을 위한 Omeprazole , Colloidal Bismuth Subcitrate , Amoxacillin 3제 요법의 효과
김기찬(Gi Chan Kim),정보윤(Bo Yoon Jung),곽성진(Sung Jin Gawk),유해진(Hae Jin Ryu),홍상인(Sang In Hong),박흥진(Heung Jin Park),정성균(Seong Kyoon Cheong),오인택(In Taek Oh),이재동(Jae Dong Lee) 대한소화기학회 1996 대한소화기학회지 Vol.28 No.5
N/A Backgroud/Aims: Helicobacter pylori infection is closely associated with chronic gastritis and peptic ulcer. The recurrence rate of duodenal ulcer within 12 months after treatment is seventy to ninty percent. However, many studies have demonstrated that the eradication of H. pylori infection had reduced the relapse rate of duodenal ulcer significantly. Methods: We have investigated a short term H. pylori eradication regimen consisting of Colloidal Bismuth Subcitrate(CHS) 240 mg b.I.d for two weeks, omeprazole 20 mg s.d for two weeks, amoxacillin 250 mg t.I.d for one week. Our study included 150 patients with duodenal ulcers confirmed by endoscopy. Results: Eight-four percent of those patients were CLO test positive. Following two weeks of therapy, ninty-seven percent of patients had healing ulcers confirmed by endoscopy and 84.7% of patients, previously urease positive, had converted to urease negative. The eradication rate of H. pylori(using the CLO test) determined at four weeks after the treatment was fifty-two percent. Conclusions: During the course of treatment, none of the patients experienced any significant side effects. The triple regimen therapy appears to be safe and well tolerated. We have concluded that the triple regimen therapy is an effective treatment of H. pylori positive duodenal ulcer in our trial group. (Korean J Gastroenterol 1996;28:617 - 622)
김기찬,김열홍,홍상인,박흥진,원동준,안승혜,정보윤 대한내과학회 1995 대한내과학회지 Vol.48 No.1
Chronic lymphocytic leukemia (CLL) of T cell origin (T-CLL) is extremely rare but one case has reported in Korea. We have experienced a case of T4-CLL, which was confirmed by immunophenotyping panel and monoclonal antibody of lymphocytes and we want to present the case with a review of the literature. A 86-year-old woman admitted to the department of internal medicine Seoul Adventist Hospital on September 9th, 1993 with febrile sensation end multiple itchy eruptions on face and both extremities. Homoglobin was 10.2g/dl, hematocrit 32.2%, reticulocyte count 2.7%, platelet 221,000/㎣ and white blood cell count was, 71,000/㎣ with 5% segments and 79% lymphocytes. Albumin was 3.5g/dl and total globulins were 8.2g/dl. Quantitative immunoglobulins were within normal limits. Bone marrow aspiration and biopsy was done. Myeloid series showed normal distribution, erythroid series revealed normoblastic erythropoiesis. Lymphocytes were increased in number (40%). Marrow cellularity was 50% and mature lymphocytes were increased in number by interstitial type. The results of surface marker studies of leukemic cells were SmIg: IgG 16%, SmIg: IgM 7%, SmIg: Lambda 17%, Smig: Kappa 10%, Monoclonal antibody tests of leukemic cells were T1: 96%, T3:93%, T4:98%, T11:99%, Ia:74%, 3A1:93% and J5, b1, B4 were negative.
내시경적 " O "-형 밴드 결찰술로 제거된 식도 과립세포종 1예
이효진,박종욱,이재동,오인택,곽현철,석윤철,홍상인,박흥진,곽성진 대한소화기내시경학회 1996 Clinical Endoscopy Vol.16 No.1
The first case report of granular cell tumor was by Abrikossoff in 1926, the tumor has been named with more than 20 different synonyms. It is found usually in the tongue, oral cavity, and the skin. It occurs rarely in the esophagus. Esophageal granular cell tumor is a benign lesion which can be diagnosed by endoscopic biopsy. Large symptomatic lesion can be removed by polypectomy. A 29-year-old female visited our hospital for intermittent epigastric pain and anterior chest discomfort. Endoscopy showed a 0.6 *0.4 cm whitish yellow nodule in the mid-esophagus, 25 cm from the incisor teeth. Endoscopic polypectomy was performed with $quot;O$quot;-type rubber band for endoscopic variceal ligation(EVL). A case of esophageal granular cell tumor conformed by S-100 protein stain is reported with the review of literature.