http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
사군자탕(四君子湯)이 TNBS로 유발(誘發)된 생쥐의 염증성(炎症性) 장질환(腸疾患)에 미치는 영향(影響)
홍상선,류봉하,윤성우,김진성,Hong, Sang-Sun,Ryu, Bong-Ha,Yoon, Seong-Woo,Kim, Jin-Sung 대한한방내과학회 2010 大韓韓方內科學會誌 Vol.31 No.4
Objectives : The present study aimed to find out the effect of Sagunja-tang on the prevention and treatment of inflammatory bowel disease using mice with TNBS-induced inflammatory bowel disease. Methods : Mice with TNBS-induced inflammatory bowel disease were medicated with Sagunja-tang, and the weight changes, colon length, lipid peroxidation, and myeloperoxidase activity were observed. Levels of the inflammatory markers interleukin (IL)-$1{\beta}$ and cyclooxygenase-2 (COX-2), its transcription factor activation, phospho-NF-${\kappa}$B (pp65), in the colon by enzyme-linked immunosorbent assay and immunoblot analysis were also measured. Finally, the activation of fecal bacterial enzyme, ${\beta}$-glucuronidase and degradation activation of fecal glycosaminoglycan (GAG) and hyaluronic acid were observed. Results : We found that oral administration of Sagunja-tang inhibited TNBS-induced colon shortening and also inhibited myeloperoxidase activity in the colon of mice as well as IL-$1{\beta}$ and COX-2 expression. Sagunja-tang also inhibited TNBSinduced lipid peroxidation and pp65 activation in the colon of mice. In addition, Sagunja-tang inhibited ${\beta}$-glucuronidase activation and fecal hyaluronic acid degradation activation. Conclusions : It is supposed that Sagunja-tang has a potential therapeutic effect on inflammatory bowel disease through the inhibition of both NF-${\kappa}$B activation and lipid peroxidation, and the improvement of intestinal conditions.
김진석,홍종희,홍상선,임중화,한숙영,김진성,윤상협,류봉하,류기원,박석규,Kim, Jin-Seok,Hong, Jong-Hee,Hong, Sang-Sun,Lim, Joong-Hwa,Han, Sook-Young,Kim, Jin-Seong,Yoon, Sang-Hyub,Ryu, Bong-Ha,Ryu, Ki-Won,Park, Seok-Kyu 대한한방내과학회 2002 大韓韓方內科學會誌 Vol.23 No.2
Functional dyspepsia refers to upper abdominal pain or discomfort with or without symptoms of early satiety, nausea, or vomiting with no definable organic cause. In this study, we recognized that dyspepsia was decreased with herbal medication (Banhabakchulchunma-tang) and acupuncture therapy. And we aimed to evaluate the Gastrointestinal Symptoms Rating Scale (GSRS) in these cases. The GSRS indicated that Oriental medicine treatment could be effective in the Functional dyspepsia. And it is helpful in decreasing symptoms of patients and in improving quality of life.
류봉하,김진성,윤상협,류기원,홍상선,Ryu Bong-Ha,Kim Jin-Sung,Yoon Sang-Hyub,Ryu Ki-Won,Hong Sang-Sun 대한한방내과학회 2003 大韓韓方內科學會誌 Vol.24 No.2
Background : Nowadays many researches about it s cure are going on world widely since cancer is one of the most human health threatening diseases. In Chinese and North Korean medicine, Duchesnea india(Audra.) Foche. is practically used to treat many kinds of cancer, but in Korea it is rarely used. So, we need to scientifically identify anti-tumor effects of Duchesnea india(Audra.) Foche. Objective : We are aimed to identify anti-tumor effects of Duchesnea india(Audra.) Foche. on the stomach cancer cells through molecular biologic methods. Material & Methods : We used AGS as stomach cancer cells from American Type Culture Collection. We added the boiled extract of Duchesnea india(Audra.) Foche. $5{\mu}l$(Sample I), $10{\mu}l$(Sample II) to cultural media(ml)for 0,6, 12, 24, 48 hours. We measured the killing effect on stomach cancer cells through Tryphan blue exclusion test and the suppressive effect on viability of stomach cancer cells via MTT assay. the quantitative RT-PCR was used to examine their effect on the revelation of Bcl-2, Bcl-XL, and Bax, which are genes related to apoptosis. We measured change of mitochondria membrane permeability and membrane potential via flow cytometry. Result : 1. The killing effect on stomach cancer cells showed that each test groups killed more stomach cancer cells than the control group with a time(6 hours later) and density dependent manner, which was statistical significance. 2. The suppressive effect on viability of stomach cancer cells showed that each test groups had more suppressive effects on viability of stomach cancer cells than the control group with a time(6 hours later), which was statistical significance. 3. In the test about the revelation of genes related to apoptosis, the revelation of Bcl-2 and Bcl-XL decreased with a density manner which was statistical significance. but the revelation of Bax was not changed with statistical significance. 4. As a result of this test, Duchesnea india(Audra.) Foche. caused apoptosis by decreasing the absorbance of mitochondria with statistical significance. and also induced apoptosis by decreasing the membrane potential of mitochondria. Conclusion : This experiment showed that Duchesnea india(Audra.) Foche. has anti-tumor effect with statistical significance. This is in vitro experiment and basic experiment on Duchesnea india(Audra.) Foche. We hope more progressive researchs on Duchesnea india(Audra.) Foche. will go on and its anti-tumor effects will be more practically identified.
뇌경색 발병후 병발된 만성 애역(Chronic hiccup)의 뜸치료 1례
전우현,김진석,홍종희,홍상선,박석규,김진성,류봉하,류기원,박재우,Jeon, Woo-Hyeon,Kim, Jin-Seok,Hong, Jong-Hee,Hong, Sang-Sun,Park, Seok-Kyu,Kim, Jin-Seong,Ryu, Bong-Ha,Ryu, Ki-Won,Park, Jae-Woo 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.1
Hiccups, also known as singultus, are spasmodic involuntary contractions of respiratory muscles that shorten respiration. The characteristic sound is caused by rapid closure of the glottis. In oriental medicine, the mechanism of hiccups is "reversed flow of Ki". Hiccups have been associated with neoplasm, infections, seizures, diabetes. renal failure, alcohol ingestion, various drugs, and ischemic events of the myocardium or central nervous system. We present a case of chronic hiccups after cerebral infarction that was successfully treated using moxibustion therapy.
김병기 ( Byung-gi Kim ),홍상선 ( Sang-sun Hong ),전영길 ( Young-keel Jouhn ) 한국인터넷정보학회 2004 인터넷정보학회논문지 Vol.5 No.1
컴퓨터 네트워크에서 고려해야 할 두 가지 중요한 보안 문제는 안전한 자료 전송과 사용자 인증에 관한 것이다. 특히 무선 LAN에서는 이 문제가 더욱 심각하기 때문에, 무선 LAN을 기반으로 하는 개인 네트워크 환경과 유비쿼터스 네트워크에서 보안 문제가 중요한 이슈로 떠오르고 있다. 본 논문에서는 이런 환경에서 이용 가능한 인증 시스템인 UPMA(Ubiquitous Personal Mutual Authentication) 모델을 제안한다. UPMA 모델은 각 시스템에 대해 개인의 확인이 가능한 인증구조를 지원한다. 세션 키 설정 과정을 통하여 통신 내용을 기밀화하고, 통신자 각각의 장비와 사용자를 확인함으로써 상호 동등한 인증을 수행한다. 제안하는 방법은 네트워크를 통한 인증서버와의 접속 없이 접속자간 인증 또는 시스템 간의 인증으로 접속단말 간 상호인증을 실현하여 유비쿼터스 네트워크에서의 보안 문제를 해결한다. UPMA 모델은 인터넷 또는 공공의 네트워크를 통하여 글로벌 로밍 서비스를 가능하게 하는 글로벌 인증 시스템이며, 이것은 또한 회사 내부의 네트워크와 홈 네트워크에 안전하고 쉽게 접속할 수 있도록 개발된 적절한 보안 인증 시스템이다. Two general security measures in computing networks are secure data transmission and user authentication. These problems are still critical in the wireless LAN environments. Thus security becomes most significant issue in personal network environments and ubiquitous networks based on wireless LANs. We purpose a new authentication system for these kind of environments, and coined it UPMA(Ubiquitous Personal Mutual Authen-tication) model. UPMA supports authenticating configurations which provides personal verification for each system. It guarantees secure communications through the session key setup, and provides mutual authentication by verifying each user and his/her station. UPMA solves security problems in ubiquitous networks without accessing authentication server. Instead it performs mutual authentication between terminals or between systems. It is a global authentication system which enables global roaming service through the Internet or other public networks. It can be used to guarantee safe and convenient access to a company Intranet or to a home network.
기능성 소화불량증 환자의 한방치료후 삶의 질 변화에 대한 임상적 평가
박재우,김진석,홍종희,홍상선,박석규,김진성,윤상협,류봉하,류기원,전우현,Park, Jae-Woo,Kim, Jin-Seok,Hong, Jong-Hee,Hong, Sang-Sun,Park, Seok-Kyu,Kim, Jin-Seong,Yoon, Sang-Hyub,Ryu, Bong-Ha,Ryu, Ki-Won,Jeon, Woo-Hyeon 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.3
Objectives: Patients with functional dyspepsia frequently complain the discomfort of daily life, so their quality of life shows a tendency to decrease. This study was aimed to investigate the usefulness of oriental medical treatment for quality of life in patients with functional dyspepsia Methods: Quality of life in 15 patients was assesed by two times questionnaire based on Korean health related Quality of Life(KQOLS) Results: The mean of KQOLS score was 122.87 before oriental medical treatment, and after treatment, the mean of score was significantly reduced to 101.60(p=0.003). The score of each domains in KQOLS was also reduced significantly in psychological health, role limitation, pain, vitality respectively(p<0.05). Conclusions: We suggest that oriental medical treatment can improve quality of life in patients with functional dyspepsia.