CRST 증후군에 대한 Reserpine 의 동맥내 주사효과

박재우,신실,손숙자 대한피부과학회 1981 大韓皮膚科學會誌 Vol.19 No.6

The CRST syndrome, first reported by Winterbauer, represents a benign variant of scleroderma and consists of calcinosis(C), Raynauds phenomenon(R), sclerodactyly(S) and telangiectasia(T). The authors report a case of CRST syndrome confirmed by both clinical and histopathological findings. A 62-year-old female developed subcutaneous nodules on both elbow and knee joints, Raynauds phenomenon, sclerodactyly with acrosclerosis and scleroderrnatous changes on both hands and forearms and telangiectasia on the face, neck, and hands of 15 years duration, but she had no difficulty in swallowing. The authors treated a case of CRST syndrome with weekly intra-arterial administration of reserpine and were impressed not only by the marked loosening of the skin but also by the striking effect on the Raynauds phenornena; the latter disappeared within a few weeks of treatment.

미세유체 기반의 플랫폼을 이용한 미지의 백색가루 간이식별 탐지방안

박재우,송지영,나상철,변기식,전누리 한국군사과학기술학회 2017 한국군사과학기술학회지 Vol.20 No.6

Terrorists always threats the global security with the possibility of using prohibited warfare, NBCs(Nuclear, Biological and Chemical Warfare). Compared to other prohibited warfares, most of biological warfare agents (BWAs) have no physical properties and time delays from spread to affect. Therefore the early detection is important to protect and decontaminate from BWAs. On the preliminary detection stage for suspicious material, most of detection kits only serve to know weather the BWAs exists or not. Due to this reason, simple field confirmation testing for suspicious substances have been used to identify materials which show negative result on detection kits. Considering the current Lab on a Chip(LOC) technologies, we suggest simple identification platform for unknown suspicious substances based on paper fluidics. We hope that our research will envision the future direction for the specific point-of-view for LOC technologies on detection strategy of BWAs.

공공시설물 지진대응을 위한 중요도 평가기준에 관한 연구

박재우,김석 한국산업융합학회 2018 한국산업융합학회 논문집 Vol.21 No.6

The perception of earthquake in Korea has changed due to the earthquake that occurred in Gyeongju and Pohang, and the earthquake has become an important factor in infrastructure management. Damage to infrastructures in the event of an earthquake is extensive. In particular, damage to infrastructures that perform public function used to spread to the whole area. From the point of view of earthquake disaster prevention, it is very important for the public to define what infrastructures are important management targets and to prepare a countermeasure. In this study, we propose a method to evaluate the importance of infrastructure to effectively manage infrastructures for earthquakes. For this purpose, important factors for the railway bridges, power generation and electric power facilities, and apartment complexes are suggested. AHP analysis is conducted to suggest priorities. In addition, the evaluation criteria for infrastructure importance are presented.

토공현장 적용성 검증을 위한 MMS 정밀도 분석

박재우,김석 한국산업융합학회 2019 한국산업융합학회 논문집 Vol.22 No.2

Researches utilizing the fourth industrial revolution technology are being conducted as a breakthrough for improving the earthworker productivity. In order to make the earthwork site smarter, it is necessary to digitize the construction site topography at first. For this purpose, photogrammetry using drones and LiDAR on MMS have been recently used. The purpose of this study is to analyze the accuracy of LiDAR by installation angles for verifying the application of MMS in the construction site. As a result of comparing the coordinates measured by the total station and the LiDAR, a small error of about 1-2 centimeters was shown. It is confirmed that MMS could be well applied to the earthwork site. In addition, there was no significant difference in the accuracy of the acquired coordinates according to the installation angle of the LiDAR, but the shape of the point clouds was different. The larger the installation angle, the better the shape of the site terrain is measured.

고려전기 영토관념과 邊境

박재우 한국중세사학회 2013 한국중세사연구 Vol.0 No.35

Goryeo had a view of world different from China. The view of world was expressed as Yodong and Haedong. Even though not all areas in the east of Yoha were directly governed by Goryeo, the ruler of Goryeo was called the emperor of Haedong, and Haedong was recognized as the ruling area of the ruler of Goryeo. This was originated from the historic dominium that the ruler of Goryeo inherited Gija and Jumong’s state, and the space governed by Gija and Jumong was also governed by Goryeo. The surrounding states recognized these areas as the Goryeo’s territory. Such concept played an important role when there is any conflict on territory. The concept that Yodong was the territory of Goryeo was expressed when Gangdong 6 Ju was pioneered in relation to the Khitan, 9 fortresses were developed in relation to the Jurchen and the justification of Dongnyeongbu conquest was explained. The territory concept focusing on Yodong demonstrated the recognition of the border of Goryeo and it was understood as 3 sides were surrounded by sea and the north was linked to land. When the northern area was seen, extensive area called Bukgye and Donggye was recognized as border. The Guanfang was installed when Cheollijangseong was constructed at the outer border, and Guanfang was also installed in Uiju in the border of Amrok River. These areas played a role of border in a narrow sense. Although there was Beon at the outer area of border, when the Jurchen was subordinated, the border of Goryeo was expanded beyond Cheollijangseong, where Gimiju was installed. Since then, when 9 fortresses were installed in Gimiju area which were returned later, the border was restricted to Cheollijangseong. The border in the south was border against the late Baekje during the late Three Kingdoms’ war. But, such awareness disappeared after the unification. Instead, the sea coast was recognized as border. During the Jurchen pirate invasion, the east sea coast was recognized as border, and in the southern area, not only sea coast but also islands were recognized as border. It was because islands were recognized as territory and governed by the Gunhyeon system and managed as the Goryeo’s territory due to the comings and goings of diplomats or pirates’ invasion incidents.

Irinotecan을 포함한 선행치료를 받은 전이 및 재발 대장암에서 Cetuximab과 FOLFIRI 병합치료 효과의 후향적 분석

박재우,문선미,황대용 대한대장항문학회 2008 Annals of Coloproctolgy Vol.24 No.5

Purpose: Many reports about efficacy of cetuximab in the prolongation of survival have been published. Especially, the combination of cetuximab and FOLFIRI has a high activity even in prior irinotecan refractory metastatic colorectal cancer (mCRC). Beside small number of patients, we are trying to evaluate the efficacy and safety of cetuximab combined with FOLFIRI for patients who prior irinotecan chemotherapy had failed. Methods: A retrospective analysis of 26 patients treated with cetuximab with FOLFIRI from July 2006 to August 2007 was done. All patients had already been treated with FOLFIRI chemotherapy in 1st line or 2nd line regimens for mCRC. The initial dose of cetuximab was 400 mg/m2 at the 1st week, after which the dose was 250 mg/m2 weekly plus FOLFIRI biweekly. We defined 1 cycle as 8 weeks, and the responses were evaluated at week 8. Results: The median follow-up period was 6.2 (1.1∼13.9) months. After 8 weeks, 50% of the patients had a partial response, and the disease control rate was 57.5%. The median time to progression was 3 months. EGFR expression and tumor response had no correlation (P=0.07). Skin reaction and tumor response (median time to progression) had a significant correlation (P= 0.022). Cetuximab did not increase the toxicity associated with FOLFIRI, except for an acneiform rash. Conclusions: Cetuximab combined with FOLFIRI chemotherapy was effective in treating mCRC patients after FOLFIRI regimen chemotherapy.

Structural behavior of CFRP strengthened concrete-filled steel tubes columns under axial compression loads

박재우,최성모 국제구조공학회 2013 Steel and Composite Structures, An International J Vol.14 No.5

This paper presents the structural behavior of CFRP (carbon fiber reinforced polymer) strengthened CFT (concrete-filled steel tubes) columns under axial loads. Circular and square specimens were selected to investigate the retrofitting effects of CFRP sheet on CFT columns. Test parameters are cross section of CFT, D/t (B/t) ratios, and the number of CFRP layers. The load and ductility capacities were evaluated for each specimen. Structural behavior comparisons of circular and rectangular section will be represented in the experimental result discussion section. Finally, ultimate load formula of CFRP strengthened CFT will be proposed to calculate the ultimate strength of CFRP strengthened circular CFT. The prediction values are in good agreement with the test results obtained in this study and in the literature.

여몽전쟁 후반기 강화 추진과 무신

박재우 한국중세사학회 2020 한국중세사연구 Vol.0 No.63

It was understood that the peace during the war between Goryeo and Mongolia was promoted by civil ministers. So It wasn't interested in the role of the military subjects. However, in the second half of the Goryeo and Mongolian wars, both civil ministers and military subjects participated in the promotion of the peace. Therefore, it is necessary to have a balanced understanding of the promotion of peace. The military subjects engaged in diplomatic activities promoting peace with civil ministers. The diplomatic ambassadors of civil ministers and military subjects served to stop the Mongol invasion, withdraw the Mongolian army, and end the war. Jaechus led discussion of the peace. The civil ministers and military subjects of the 3-4 ranks did not differ from those of the Jaechus. The Jaechus of civil ministers and military subjects were discussed at the policy meeting for the promotion of peace and the end of the war. Jaechus, who promoted peace, agreed to peace without distinction between civil ministers and military subjects, and were active in promoting peace. Jaechus had many family members and party members of the Choi's regime, and they led the peace discussion. It was because they were supported by the Choi's regime and had greater influence in the bureaucratic society than other bureaucrats. There were reasons for promoting the peace together with civil ministers and military subjects. Mongolia's offensive threatened the national destiny, the political and military centripetal power of the Choi's regime weakened, the bond of the family and the party weakened, and the even if the Choi's regime collapsed, it was able to maintain the position of the ruling class. The promotion of peace in the second half of the war between Goryeo and Mongolia must be seen as pursued by civil ministers and military subjects.

고려 최씨정권의 政房 운영과 성격

박재우 한국중세사학회 2014 한국중세사연구 Vol.0 No.40

The military generals who seized power as well as control over the government with armed forces did not abandon the civil system of administration entirely, and instead decided to use it to their favor in order to wield more power. This kind of trend was reinforced during the Choi regime. Choi Chung-heon gained control of the government, and was appointed to many illustrious posts, including the prime minister seats, heads of the Ibu and Byeongbu offices, head of the monitors office and also that of the supreme commander. Choi Ih and Choi Hang also walked the same path, while Choi Eui was assassinated before he was able to secure such posts. Leaders of the Choi house intended to exclude the Ibu and Byeongbu offices from the governmental appointment process, and wanted to monopolize the authority to select and appoint governmental officials. They used another location other than the palace for the process, such as private civilian residences or the Jeongbang hall. It should be noted that all the appointments authorized them were not illegally processed ones based upon unjustified and unwarranted use of authority. At the time the people behind such processes, the Choi house leaders, were already assigned to the head posts of Ibu and Byeongbu, and were legally authorized to intervene in the appointment processes. The appointment orders were issued from private places, but they were issued by entities who were entitled to do so. The process too was not to select private servants for the Choi house, so it was recognized and acknowledged as official functions of the government. The Choi regime leaders who had stronger power than the king, used their own authority and power as heads of the Ibu and Byeongbu offices. This shows us that even during the military regime period, Goryeo’s administrative system was still functioning. The Choi regime did not abandon it or replace it with yet other ruling system, but wielded its power by seizing control of the administrative system itself. The installation of the Jeongbang(政房) office was also intended to do just that, monopolizing the official appointment process in order to get control over the entire administrative system.

고려전기 宰樞의 임용 방식과 성격

박재우 한국사연구회 2004 한국사연구 Vol.125 No.-