결합제의 종류와 양에 따라 분무건조된 페라이트 분말의 성형특성

홍대영,변순천,제해준,홍국선 한국세라믹학회 1995 한국세라믹학회지 Vol.32 No.9

Mn-Zn ferrite granules were formed by a spray-drying method of the slurry containing different kinds and concentrations of binders at various temperatures. The slurry was made by conventional ceramic processing method, that is, by mixing Fe2O3, MnO, ZnO powders (52 : 24 : 24 mol%), calcining and milling. Typical shape of the spray dried granules was spherical. The compaction behavior of these granules was dependent on the spray-drying temperature and the kind and concentration of binders. At lower pressure the granules were displaced and at higher pressure the granules were deformed and fractured to fill pores among the granules. The optimum concentration of the binder was 0.5wt%. The granules containing 0.5wt% PVA 205 were deformed and fractured well and the green density was higher than others. At higher concentrations of the binder the granules were deformed rather than fractured, therefore the green density was lowered because of the remaining unfilled pores. The decomposition temperature and the heat released were increased with increasing the concentration of the binders. The compaction response of the granules containing PVA 205 was more efficient than those containing PVA 217 and PVA 117. Green density was not dependent on the degree of hydrolysis of the binders. The compaction response of the granules spray-dried at 15$0^{\circ}C$ was most efficient.

유기인계-피레스로이드계 혼합제제 농약에 의한 중독

홍대영,백광제,이경룡,권운용,박준석,어은경,오범진,이미진,이성우,서주현,노형근,김준식,Hong, Dae-Young,Baek, Kwang-Je,Lee, Kyeong-Ryong,Kwon, Woon-Yong,Park, Joon-Seok,Eo, Eun-Kyung,Oh, Bum-Jin,Lee, Mi-Jin,Lee, Sung-Woo,Suh, Joo-Hyun,Roh, 대한임상독성학회 2007 대한임상독성학회지 Vol.5 No.1

Purpose: Owing to organophosphate-pyrethroid mixtures are widely used, suicidal or unintentional poisoning is common. But there have been relatively few reports of poisoning. The purpose of this study is to evaluate the difference of the severity and toxicity between organophosphate-pyrethroid mixtures poisoning and single organophosphate poisoning. Methods: From August 2005 to July 2006, 65 patients presented with organophosphate-pyrethroid mixtures poisoning to emergency medical center. Date were gathered by report form it was drawn up. Results: 65 patients were enrolled in 28 hospitals and their mean age was $56.5{\pm}16.2$ years old. The most common cause of poisoning was suicide, in 52 cases(80%). Chlorpyrifos-cypermethrin, malathion-esfenvalerate were the most frequent chemicals involved, and the mean ingestion amount was 135.4ml. The most common symptom of the patients was nausea/vomiting, in 16 patients. The average GCS score was 13. The mean ICU stay was $4.4{\pm}5.2$ days, and mortality was 3.1%. Conclusion: The severity and toxicity of organophosphate-pyrethroid mixture poisoning were lower than that of single organophosphate poisoning.

Expression of VEGF, HGF, IL-6, IL-8, MMP-9, Telomerase in Peripheral Blood of Patients with Head and Neck Squamous Cell Carcinoma

홍대영,이병주,이진춘,왕수건,최진식,노정훈 대한이비인후과학회 2009 Clinical and Experimental Otorhinolaryngology Vol.2 No.4

Objectives. This study investigated the telomerase expression in peripheral blood mononuclear cells (PBMCs) and the relationship between the serum level of several soluble factors such as vascular endothelial growth factor (VEGF), hepatocyte growth factor, interleukin (IL)-6, IL-8, and matrix metallopeptidase-9 and the clinicopathological features of patients with head and neck squamous cell carcinoma (HNSCC). Methods. Peripheral blood samples were collected from 50 HNSCC patients and 15 normal controls. The telomerase activity in the PBMCs was measured by Telomere Repeat Amplification Protocols. The serum levels of the soluble factors were analyzed by enzyme-linked immunosorbent assay. Results. The expression of telomerase in the PBMCs of HNSCC patients was significantly correlated with the N and American Joint Committee on Cancer (AJCC) stages. The serum VEGF level was significantly higher in the patients with an advanced T stage, N stage and AJCC stage. Serum VEGF was significantly related with the expression of telomerase in the PBMCs. The telomerase expression and the VEGF expression were shown to be independent factors associated with poor survival. Conclusion. The telomerase expression in the PBMCs and the serum VEGF level of HNSCC patients were significantly correlated with the N stage, the AJCC stage and the prognosis. Objectives. This study investigated the telomerase expression in peripheral blood mononuclear cells (PBMCs) and the relationship between the serum level of several soluble factors such as vascular endothelial growth factor (VEGF), hepatocyte growth factor, interleukin (IL)-6, IL-8, and matrix metallopeptidase-9 and the clinicopathological features of patients with head and neck squamous cell carcinoma (HNSCC). Methods. Peripheral blood samples were collected from 50 HNSCC patients and 15 normal controls. The telomerase activity in the PBMCs was measured by Telomere Repeat Amplification Protocols. The serum levels of the soluble factors were analyzed by enzyme-linked immunosorbent assay. Results. The expression of telomerase in the PBMCs of HNSCC patients was significantly correlated with the N and American Joint Committee on Cancer (AJCC) stages. The serum VEGF level was significantly higher in the patients with an advanced T stage, N stage and AJCC stage. Serum VEGF was significantly related with the expression of telomerase in the PBMCs. The telomerase expression and the VEGF expression were shown to be independent factors associated with poor survival. Conclusion. The telomerase expression in the PBMCs and the serum VEGF level of HNSCC patients were significantly correlated with the N stage, the AJCC stage and the prognosis.

반복적 허혈증상을 유발하는 척추동맥의 개창성기형- 증 례 보 고 -

홍대영,김문철,이상평,최기환,여형태 대한신경외과학회 2002 Journal of Korean neurosurgical society Vol.31 No.1

In angiographic examinations, abnormalities of vertebral arteries are incidental findings because they are, in most of cases, clinically asymptomatic. We report a case of young woman with a fenestrated anomaly of the left vertebral artery with ischemic strokes. The patient was suffered from repeated attacks of transient ishemic attack(TIA) and cerebral infarction. Vertebral angiography demonstrated a fenestrated anomaly of the left vertebral artery and a large intraluminal thrombus was detected at just proximal of the fenestration. Proximal balloon occlusion of the involved vertebral artery was done and the patient became free from ischemic attack. Follow-up angiography showed well visualization of the posterior circulation through right vertebral artery and the ballooned vertebral artery was well occluded. The left posterior inferior cerebellar artery(PICA) was filled well via collateral circulation from the opposite side. Key words:Ischemic stroke;Fenestrate vertebral artery;Balloon embolization.

1920년대 민요시의 재인식 - 민요시의 율격을 중심으로

홍대영 대구대학교 국어교육과 1997 나랏말쌈 Vol.12 No.-

두개내압 상승 평가에서 초음파를 이용한 시각신경집 지름 측정의 유용성

홍대영,조순구,고영길,김강호,이경미,김지혜,김준식,한승백,이훈재 대한응급의학회 2006 大韓應急醫學會誌 Vol.17 No.3

Dicamba 급성 중독으로 인한 사망 1례

홍대영,엄욱현,이경미,김지혜,한승백,서주현,김준식,노형근,Hong Dae-Young,Um Wook-Hyun,Lee Kyoung-Mi,Kim Ji-Hye,Han Seung-Baik,Suh Joo-Hyun,Kim Jun-Sig,Roh Hyung-Keun 대한임상독성학회 2006 대한임상독성학회지 Vol.4 No.1

Dicamba is a benzoic acid and classified as a chemically related chlorophenoxy herbicide which is widely used for the control of broad-leaved weeds. While the chlorophenoxy herbicide poisoning is known to be uncommon, its ingestion can result in serious or sometimes fatal outcome. A 65-year-old man ingested about 300 ml of dicamba in a suicidal attempt and three hours later he was admitted hospital, complaining abdominal pain, nausea and vomiting. On admission his vital signs were normal and laboratory findings were not remarkable except metabolic acidosis in arterial blood gas analysis. Shortly after the admission endotracheal tube was inserted due to altered mental state and activated charcoal was given after performing gastric lavage. However, his vital signs became unstable 6hrs after the ingestion and mechanical ventilation was started with administration of inotropic agents. In spite of urine alkalization for rapid elimination of the absorbed dicamba, the metabolic acidosis was aggravated with concomitant rhabdomyolysis and acute renal failure, and he died 24 hrs after the ingestion.

悲魂

홍대영 대구대학교 국어교육과 1993 나랏말쌈 Vol.8 No.-

비외상성 척추 경막외 혈종

홍대영,김문철,이상평,최기환,여형태 대한신경외과학회 2002 Journal of Korean neurosurgical society Vol.31 No.1

Spontaneous spinal epidural hematoma is a rare entity. Various definitions for spontaneous epidural hematoma have been reported in the literature. The expression of nontraumatic spinal epidural hematoma seems to be less ambiguous and includes idiopathic hematomas and hematomas secondary to coagulopathy, vascular malformations, and tumors. We report three cases of nontraumatic spinal epidural hematomas observed from 1991 to 2000. The causes of the spinal epidural hematomas were not clear in two cases among them, but in the another one case, the cause was determined to be an acquired coagulopathy. We reviewed 24 cases reported in the Korean Journal of Neurosurgery and our three cases with particular emphasis on the various causes such as coagulopathy, vascular malformations and tumors. Among the 27 cases, numerous causes were detected such as three cases of vascular malformation, one case of anticoagulant treatment, five cases of combined lumbar disc herniation, two cases associated with pregnancy and postpartum, one case associated with hypertension, and one case associated with ossification of ligamentum flavum. No causes were detected in the ten cases. The authors reviewed the literature. Key words:Nontraumatic spinal epidural hematoma;Etiology. 연령과 남녀비 4세에서 82세까지 다양하게 분포하였고 평균나이는 37.6세였다. 남자가 20명 여자가 7명(2.9:1)으로 보고되었다. 병력과 혈종원인 및 직업 총 27례 중 혈관기형 3례(수술시야에서 확인한 다음 조직검사에서 확진한 경우), 항응고제 사용의 합병증 1례, 추간판 탈출증을 동반한 경우가 5례, 임신과 출산이 관련된 경우가 2례, 고혈압이 있은 경우가 1례, 황인대 골화증과 동반된 경우가 1례였다. 이 중 직업상 군인, 유도선수, 농구선수거나, 병력 상 무거운 물건을 든 후, 태권도 후와 같이 반복적인 minor trauma가 있을 것으로 추정되는 경우가 8례였다. 어떠한 형태의 원인도 찾을 수 없었던 경우는 총 10례였다. 수술 전 신경학적 결손정도 및 술 후 예후 27례에서 모두 수술을 시행하였고 이 중 수술 전 불완전마비인 16례 중 술 후 완전회복 8례, 부분회복 7례, 변화없음 1례였고 수술 전 완전마비인 6례 중 술 후 완전회복 2례, 부분회복 3례, 변화없음 1례로 보고 되었다. 또한 수술 전 신경근 증상만 보인 5례는 전례에서 완전회복을 보였다.

문서 분류의 개선을 위한 단어-문자 혼합 신경망 모델

홍대영,심규석 한국정보과학회 2017 정보과학회논문지 Vol.44 No.12

문서의 텍스트를 바탕으로 각 문서가 속한 분류를 찾아내는 문서 분류는 자연어 처리의 기본 분야 중 하나로 주제 분류, 감정 분류 등 다양한 분야에 이용될 수 있다. 문서를 분류하기 위한 신경망 모델은 크게 단어를 기본 단위로 다루는 단어 수준 모델과 문자를 기본 단위로 다루는 문자 수준 모델로 나누어진다. 본 논문에서는 문서를 분류하는 신경망 모델의 성능을 향상시키기 위하여 문자 수준과 단어 수준의 모델을 혼합한 신경망 모델을 제안한다. 제안하는 모델은 각 단어에 대하여 문자 수준의 신경망 모델로 인코딩한 정보와 단어들의 정보를 저장하고 있는 단어 임베딩 행렬의 정보를 결합하여 각 단어에 대한 특징 벡터를 만든다. 추출된 단어들에 대한 특징 벡터를 바탕으로, 주의(attention) 메커니즘을 이용한 순환 신경망을 단어 수준과 문장 수준에 각각 적용하는 계층적 신경망 구조를 통해 문서를 분류한다. 제안한 모델에 대하여 실생활 데이터를 바탕으로 한 실험으로 효용성을 검증한다. Document classification, a task of classifying the category of each document based on text, is one of the fundamental areas for natural language processing. Document classification may be used in various fields such as topic classification and sentiment classification. Neural network models for document classification can be divided into two categories: word-level models and character-level models that treat words and characters as basic units respectively. In this study, we propose a neural network model that combines character-level and word-level models to improve performance of document classification. The proposed model extracts the feature vector of each word by combining information obtained from a word embedding matrix and information encoded by a character-level neural network. Based on feature vectors of words, the model classifies documents with a hierarchical structure wherein recurrent neural networks with attention mechanisms are used for both the word and the sentence levels. Experiments on real life datasets demonstrate effectiveness of our proposed model.