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      • 항암화학요법 후 발생한 위장관기종 1예

        한동재,박희순,이호성,박재만,김종화,이규택,정윤호 순천향의학연구소 2013 Journal of Soonchunhyang Medical Science Vol.19 No.2

        Pneumatosis intestinalis (PI) is a rare condition that is characterized by multiple subserosal and submucosal gas-filled areas in the bowel wall. Gastric pneumatosis describes the presence of gas within the stomach wall. This is caused by a disruption in gastric mucosa leading to the dissection of air into the wall. The extract cause of PI is still unknown; however, it may be associated with coexisting disease. Gastric PI has been rarely documented. So, we report on a 75-year-old man with acute gastric pneumatosis following his palliative chemotherapy. He underwent 3rd cycle of gemcitabine and erlotinib 3 weeks prior to admission. The treatment was started with nasogastric tube insertion and parenteral nutrition. Then, gastric pneumatosis was improved. However, the patient was died because of worsening underline disease and general condition. We suggest that chemotherapy should be considered the case of pneumatosis and careful X-ray interpretation will be necessary for detecting the pneumatosis earlier.

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        증례 : 호흡기; 쯔쯔가무시병에서 발생된 급성 전격성 심근염 1예

        한동재 ( Dong Jae Han ),박희순 ( Hee Soon Park ),김대연 ( Dae Yeon Kim ),강효철 ( Hyo Chul Kang ),이호성 ( Ho Sung Rhee ),이세환 ( Se Whan Lee ),나주옥 ( Ju Ock Na ) 대한내과학회 2013 대한내과학회지 Vol.85 No.6

        쯔쯔가무시병은 국내에서 대표적인 가을철 열성 질환의 하나이며 이로 인한 호흡부전이나 신부전은 널리 알려져 있지만 심근염은 질병의 위중함에 미루어 잘 알려져 있지 않은 합병증이다. 저자들은 85세 고령의 여성에서 쯔쯔가무시병을 적절하게 빠른 시일에 진단하였으며 그 후 항균제 투약 등 적절한처치를 시행하였음에도 불구하고 급성 심근염 및 급성 신부전으로 사망한 예를 보고하였다. Scrub typhus is an acute febrile illness caused by Orientia tsutsugamushi that is characterized by focal or disseminated vasculitis and perivasculitis. Scrub typhus can have fatal complications, such as acute respiratory distress syndrome, septic shock, and acute kidney injury. However, there are few reports of fatal myocarditis caused by scrub typhus. We present a case of acute fatal myocarditis combined with acute kidney injury complicating scrub typhus. (Korean J Med 2013;85:623-628)

      • 말기신부전 환자에서 항혈소판 제제가 혈소판기능에 미치는 영향

        김대연,박희순,한동재,이호성,김태우,정선영,김휘준,길효욱 순천향대학교 순천향의학연구소 2013 Journal of Soonchunhyang Medical Science Vol.19 No.2

        Objective: Uremic bleeding is well recognized problem. In patients with renal failure, the safety of antiplatelet therapy is doubtful and there is little data about the platelet function in dialysis patients who are prescribed antiplatelet agents. The aim of this study is to investigate the platelet function in dialysis patients who were taking antiplatelet agents. Methods: The cross-sectional study was performed on 49 patients who have been undergoing dialysis (A group, 19 patients), normal renal function (B group, 30 patients). All of them have taken aspirin and clopidogrel. The control group (C group) consisted of 30 patients who have been undergoing dialysis, not taking aspirin or clopidogrel. The in-vitro closure time was measured using a PFA-100 device that had cartridges holding a membrane with a central aperture and this was coated with either collagen/epinephrine (CEPI) or collagen/adenosine diphosphate (CADP). In vitro closure time was measured by each cartridge defined CADP and CEPI. Results: The CADP and CEPI were higher in the patients with end stage renal disease (ESRD) and who were not taking dual blockers than the normal range (CADP: 80-162, CEPI: 64-121). CADP prolonged in A group compared to C group. Hemodialysis, platelet count < 201×106/L, hematocrit, antiplatelet medication are relevant to the prolongation of CEPI and CADP in binary logistic regression analyses. Conclusion: Platelet function in ESRD patients was deteriorated irrespective of antiplatelet medication, which became even worse if they took antiplatelet drugs. Therefore, we have to take careful attention to the increased bleeding tendency of ESRD patients due to the antiplatelet drugs.

      • 갑상선 세침흡인검사 후 발생한 양측 갑상선 혈종에 의한 기도 압박

        박희순,조남준,한동재,이주영,서미혜,김여주,김상진 순천향의학연구소 2013 Journal of Soonchunhyang Medical Science Vol.19 No.2

        Fine-needle aspiration (FNA) is considered the most accurate, cost-effective and relatively safe method in the evaluation of thyroid nodules and fatal complications after thyroid FNA are uncommon. In particular, the large hematomas after FNA causing airway compromise are extremely rare complications and were reported in only a few literatures. We reported a 51-year-old woman who showed airway compromise caused by bilateral intrathyroidal and perithyroidal hematoma after FNA of thyroid. A large thyroid hematoma after FNA is a rare but possible complication and sometimes can be fatal for the patient. Proper preventive efforts should be considered while performing thyroid FNA and prompt intervention is mandatory for patients with acute hematoma after FNA.

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