시스템 개발 표준절차에 관한 연구

崔文柱 경인여자대학 1992 경인논집 Vol.- No.1

전략적 정보시스템에서 정보계획에 관한 연구

최문주 경인여자대학 1993 경인논집 Vol.- No.2

본 연구는 전략경영정보 시스템(S. I. S. : STRATEGIC INFORMATION STYSTEM)의 구축에 있어 가장 첫 단계이면서 간과하기 쉬운 정보계획(Information Planning)에 대하여 소개한다. 정보계획 조직에 있어서 정보계획팀 구성과 업무진행 단계, 사전문서화에 대한 설명, 전략적 정보계획을 작성키 위한 업무전략 검토, 정보기술전략 개발, 장기운용계획 개발의 상호관계와 계획서의 CHECK항목, 순서및 각과정과 조직의 연관 관계를 분석하여 장기운영개발에 반영시키는 부분을 소개하였다. 여기서 제시된 방법은 기업에서 필요성에 의하여 먼저 사용된 방법중 미국의 E. D. S (Electronic Data Systems)와 국내 모 그룹에서 우리실정에 맞게 시도한 방법을 참고 하였다.

효율적인 시스템 설계 및 관리를 위한 새로운 직무에 관한 연구

최문주 경인여자대학 1994 경인논집 Vol.- No.3

현재 전산 시스템의 분석, 설계, 개발, 유지, 보수, 운영등의 업무를 처리함에 있어서 업무처리 방식을 좀더 효율적으로 하기위한 새로운 직무로 개발자와 고객이서로 만족 하면서 전산시스템의 이용 효율을 극대화 하기위한 '고객지원자'라는 새로운 직무의 업무범위, 책임, 자격에 대하여 연구 소개 하였다.

Immortalization of Primary Keratinocytes and Its Application to Skin Research

최문주,이충호 한국응용약물학회 2015 Biomolecules & Therapeutics(구 응용약물학회지) Vol.23 No.5

As a major component of the epidermal tissue, a primary keratinocyte has served as an essential tool not only for the study of pathogenesis of skin-related diseases but also for the assessment of potential toxicities of various chemicals used in cosmetics. However, its short lifespan in ex vivo setting has been a great hurdle for many practical applications. Therefore, a number of immortalization attempts have been made with success to overcome this limitation. In order to understand the immortalization process of a primary keratinocyte, several key biological phenomena governing its lifespan will be reviewed first. Then, various immortalization methods for the establishment of stable keratinocyte cell lines will be explained. Finally, its application to a threedimensional skin culture system will be described.

전산정보과의 경쟁력 있는 교육과정 개발

최문주,한익주,이혜경,김상훈 경인여자대학 1997 경인논집 Vol.- No.6s

Establishment of Immortalized Primary Human Foreskin Keratinocytes and Their Application to Toxicity Assessment and Three Dimensional Skin Culture Construction

최문주,박민경,이수현,이정우,조민철,노민수,이충호 한국응용약물학회 2017 Biomolecules & Therapeutics(구 응용약물학회지) Vol.25 No.3

In spite of frequent usage of primary human foreskin keratinocytes (HFKs) in the study of skin biology, senescence-induced blockage of in vitro proliferation has been a big hurdle for their effective utilization. In order to overcome this passage limitation, we first isolated ten HFK lines from circumcision patients and successfully immortalized four of them via a retroviral transduction of high-risk human papillomavirus (HPV) E6 and E7 oncogenes. We confirmed expression of a keratinocyte marker protein, keratin 14 and two viral oncoproteins in these immortalized HFKs. We also observed their robust responsiveness to various exogenous stimuli, which was evidenced by increased mRNA expression of epithelial differentiation markers and pro-inflammatory genes in response to three reactive chemicals. In addition, their applicability to cytotoxicity assessment turned out to be comparable to that of HaCaT cells. Finally, we confirmed their differentiation capacity by construction of well-stratified three dimensional skin cultures. These newly established immortalized HFKs will be valuable tools not only for generation of in vitro skin disease models but also for prediction of potential toxicities of various cosmetic chemicals.

특별프로그램 : 대학생프로젝트 경진대회-포스터 발표 ; 혼합 유전자 알고리즘을 이용한 항공승무원 일정 할당문제의 실제사례적용

최문주,이철수,정찬혁,고영훈 대한산업공학회 2010 대한산업공학회 추계학술대회논문집 Vol.2010 No.-

공인 어린이 보행자 타겟의 옷 색상 변화에 따른 AEB 작동유무 검증

최문주(Moonjoo Choi),박상협(Sanghyeop Park),최형수(Hyeongsu Choi),김태형(Taehyoung Kim),이태희(Taehee Lee) 한국자동차공학회 2023 한국자동차공학회 춘계학술대회 Vol.2023 No.5

AEB and FCW has a certain function which could warn or intervene with break if a crash is expected by sensing objects on the road with camera, radar, rider, etc. In EuroNCAP, assessment protocol of this test is renewing. However, there have been suspicious malfunctioning accidents of automobiles, which were already certified on AEB, FCW capability verification assessment. A structure and shape of the standard dummy for car-to-person is specifically defined in ISO regulation, however, its clothes and condition are defined roughly. Therefore, there could be differences in detection levels depending on the color of an object and reflection condition as an object acknowledgement method with a camera is mainly used. To see detection level depending on the color of the dummy’s clothes, a camera was installed in front of the car and the background and object were set as binary-coded applying critical point. The movement traits of FCW and AEB depending on additional colors of the standard dummy besides the general colors were analyzed. Through this research, relations between the color of the dummy’s clothes and detection level in FCW and AEB capability were found.

사회부과 완벽주의와 마음챙김이 학업소진에 미치는 영향: 자기통제의 조절된 매개효과

오충광,최문주 한국청소년학회 2021 청소년학연구 Vol.28 No.12

This study examined the effect of socially prescribed perfectionism on academic burnout through mindfulness, and the moderated mediation effect of self-control on the relations between mindfulness and academic burnout. We surveyed and analyzed the data from a total of 994 university students using the socially prescribed perfectionism scale, mindfulness scale, academic burnout scale, self-control scale. For data analysis, correlation analysis was performed to confirm the relationship between each variable, and to verify the mediating effect of mindfulness on the relationship between social prescribed perfectionism and academic burnout and the moderating effect of self-control on the relationship between mindfulness and academic burnout. As a result of the analysis, it was confirmed that socially prescribed perfectionism affects academic burnout via mindfulness, and the mediating effect of mindfulness on the relationship between socially prescribed perfectionism and academic burnout was moderated by self-control. Implications, limitations and suggestions were discussed. 본 연구는 사회부과 완벽주의가 마음챙김을 경유하여 학업소진에 미치는 영향에 대해 살펴보고, 마음챙김이 학업소진에 미치는 영향을 자기통제가 조절하는지 살펴보았다. 이를 위해 대학생 994명을 대상으로 사회부과 완벽주의 척도, 마음챙김 척도, 학업소진 척도, 자기통제 척도를 이용하여 설문조사를 실시하였고, 수집된 자료를 분석하였다. 자료분석은 상관분석을 실시하여 각 변수 간의 관계를 확인하고, 사회부과 완벽주의와 학업소진 간의 관계에 대한 마음챙김의 매개효과와 마음챙김과 학업소진 간의 관계에서 자기통제의 조절효과를 검증하기 위하여 위계적 회귀분석을 실시하였다. 분석 결과, 사회부과 완벽주의는 마음챙김을 경유하여 학업소진에 영향을 미치고, 사회부과 완벽주의와 학업소진 간의 관계에 대한 마음챙김의 매개효과가 자기통제에 의해 조절됨을 확인할 수 있었다. 이는 자기통제 수준이 높아질수록 마음챙김이 학업소진에 미치는 강도가 변화되어 학업소진이 감소되는 것을 의미하는 것으로, 마음챙김과 학업소진의 관계는 자기통제 수준에 따라 달라짐을 시사한다. 본 연구결과를 바탕으로 사회부과 완벽주의로 학업소진을 경험하는 대학생들을 위한 효과적인 개입에 주는 시사점, 본 연구의 제한점 및 후속 연구에 대한 방향을 논의하였다.

다기관 한국 전립샘 암 등록(KPCR) 데이터베이스를 이용한 근치적 전립샘 절제술의 수술 결과 비교

유성혜 ( Sung Hye Yu ),최문주 ( Mun Joo Choi ),김청수 ( Choung-soo Kim ),서성일 ( Seong Il Seo ),정창욱 ( Chang Wook Jeong ),변석수 ( Seok-soo Byun ),이지열 ( Ji Youl Lee ),홍준혁 ( Jun Hyuk Hong ),최인영 ( In Young Choi ) 한국보건정보통계학회 2018 보건정보통계학회지 Vol.43 No.3

Objectives: Prostate cancer, commonly is rapidly increasing the incidence of prostate cancer among Korean men. Primary treatment of localized prostate cancer involves radical prostatectomy, and surgery techniques are divided into the abdominal, laparoscopic, and robotic surgery. Different surgical techniques differ in quality of life, economic aspect, and outcome of surgery and prognosis. Therefore we compared the outcomes and prognosis of patients who underwent surgery for localized prostate cancer using the multicenter Korean Prostate Cancer Registry (KPCR) database. Methods: The KPCR database collected data of 6,032 patients from five medical institutions, and data standardization and quality management were performed to ensure data integrity. We extracted data necessary for analysis from the KPCR database. We analyzed data for 3,262 patients during the period from January 2006 to December 2011. The demographic characteristics, surgical outcomes, and prognosis of patients with localized prostate cancer were analyzed. All statistical analyses were performed using one-way ANOVA, chi-square test, and post-hoc analysis. We used the Kaplan-Meier method and multivariable Cox proportional hazard regression model for biochemical recurrence-free survival rate (BCR-FS) analysis. Results: The analysis results showed that the average initial prostate specific antigen value was 10.30 ng/mL. A total of 56.7% of the patients had clinical stage T2, 43.3% had stage T1, and 64.4% of the patients had a Gleason score of more than 7. The rate of positive surgical margin was radical retropubic prostatectomy, laparoscopic radical prostatectomy, robotic-assisted laparoscopic radical prostatectomy (RALP) as 33.6%, 27% and 28.8%, respectively (p<0.001). The RALP gave excellent results for postoperative complication, and estimated blood loss (EBL). The 5-year overall BCR-FS was 77.0%, and the three surgical techniques did not differ in clinical outcomes. Cox regression analysis showed that the surgical technique did not affect the biochemical recurrence rate. Conclusions: Our study describes the characteristics of patients with localized prostate cancer and their prognosis. These results indicate that patients and medical staff can rely on information from the KPCR database for decision-making.