소경활혈탕가미방(疎經活血湯加味方)의 관절염에 미치는 효과

조주현 ( Joo-hyun Jo ),임지성 ( Ji-sung Im ),김종규 ( Jong-gyu Kim ),박중현 ( Jung-hyun Park ),최학순 ( Hag-soon Choi ),황규원 ( Geu-won Hwang ),송용선 ( Yung-sun Song ) 한방재활의학과학회 2021 한방재활의학과학회지 Vol.31 No.1

Objectives The aim of this study is to evaluate anti-inflammatory and anti-arthritic effects of Sogyunghwalhyel-tang-gamibang (SGHHTGB) in cell and animal models and also to suggest one of putative mechanisms underlying its anti-arthritic effects. Methods Enzyme-linked immunosorbent assay was applied to measure the concentrations of tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-6 and prostaglandin E2 (PGE2) in culture medium and blood serum and nitric oxide (NO) was assayed by Griess reagent. The expressions of inducible NO synthase (iNOS) and cyclooxygenase- 2 (COX-2) were analyzed by Western blot method. Results In a cell model using RAW264.7 macrophages stimulated with the endotoxin lipopolysaccharide (LPS), the drug, at its non-cytotoxic concentrations, inhibited the production of the pro-inflammatory cytokine TNF-α, IL-1β and IL-6. In addition, it suppressed the expression of the inflammatory enzyme iNOS and COX-2, and reduced the synthesis of the enzyme product NO (as stable nitrite) and PGE2 in activated macrophages. Meanwhile, in an animal model using rheumatic arthritis (RA) mice induced with injection of type II collagen antibody (CAb) and LPS, the drug improved clinical symptom of arthritis and reduced paw thickness and inflammatory cell infiltration. In blood of RA mice, the drug reduced serum levels of TNF-α, IL-1β, IL-6, nitrite, and PGE2, all inflammatory mediators produced by activated macrophages. Conclusions SGHHTGB may ameliorate CAb and LPS-induced RA in mice, presumably by inactivating macrophages that are capable of initiating joint inflammation by producing pro-inflammatory cytokines and expressing inflammatory enzymes. (J Korean Med Rehabil 2021;31(1):33-46)

척수공동증과 경추 추간판 탈출증을 진단받은 환자에 대한 한방치료의 치험 1례 보고

정범환,조주현,최승범,나현욱,김경운,Jung, Bum-Hwan,Jo, Joo-Hyun,Choi, Seung-Peom,Na, Hyun-Wook,Kim, Kyung-Woon 척추신경추나의학회 2013 척추신경추나의학회지 Vol.8 No.2

Objectives : The purpose of this clinical case is to evaluate the efficacy of Korean Medicine treatment on Syringomyelia with Herniated Intervertebral Disc(HIVD) of C-SPINE. Methods : We used Acupunture, herbal acupuncture, herbal medicine for this patient. This patient received hospital treatment for 15 days. Results : Patient's chief complain were neck pain and trapezius pain. NRS of chief complaint decreased from 6 to 2 and Patient's NDI decreased from 46 to 14. Conclusions : We experienced improvement of symptoms in this case by acupuncture stimulation, herbal medicine. and we hope this study is helpful for the treatment of Syringomyelia with HIVD of C-SPINE.

골반 변위가 있는 환자에서 추나 치료군과 자가 MET 병행군의 교정 정도 비교 연구 : 무작위 대조 연구

윤용일,허석원,배영춘,정범환,조주현,Yun, Yong-Il,Huh, Suk-Won,Bae, Young-Chun,Jung, Bum-Hwan,Jo, Joo-Hyun 척추신경추나의학회 2015 척추신경추나의학회지 Vol.10 No.1

Objectives : The purpose of this study is to compare the effect of Chuna manual treatment and Chuna manual treatment with self muscle energy techniques on patients with pelvic malposition Methods : Random allocation was done. We used Chuna manual treatment to control group and Chuna manual treatment with self muscle energy techniques to experimental group. These patient's pelvic malposition were checked by Leg length analysis, measuring Innominate measurement length, obturator foramen size and height of femur head. Results : 1)After the 3 weeks treatment, patients' inequality of leg length and Innominate measurement length were significantly reduced. 2)There was no significant difference between control group and experimental group. Conclusions : Chuna manual treatment and Chuna manual treatment with self muscle energy techniques are considered to be effective and useful in patients with pelvic malposition. But there was no significant difference between control group and experimental group.

요추 추간판 탈출증 환자 78명의 한방치료 후 디스크 재흡수 증례 보고

정범환 ( Bum Hwan Jung ),조주현 ( Joo Hyun Jo ),윤용일 ( Yong Il Yoon ),박상원 ( Sang Won Park ),김성문 ( Sung Moon Kim ),고웅 ( Ung Go ),정진수 ( Jin Soo Jung ),김정훈 ( Jung Hoon Kim ),허석원 ( Suk Won Huh ),김지원 ( Ji Won Kim 한방재활의학과학회 2016 한방재활의학과학회지 Vol.26 No.1

Objectives To analyze the resorption of herniated lumbar intervertebral disc on MRI in patients who were treated with Korean Medicine. Methods 78 patients with lumbar disc herniation were included, 47 males and 32 females. Patients` diagnosis was based on magnetic resonance imaging (MRI). All of the patients were only treated with Korean Medicine for 6 months treatment, and underwent MRI examination twice, pre-treatment and post-treatment. MR images were assessed by reduction in diameter of T2-weighted image between pre-treatment and post-treatment, and analyzed by differences in sex, age and disc type. Results 91.2% (71 people) of total patients had extrusion type. Korean medicine treatment reduced lumbar disc herniation diameter of all the patients from 7.11 mm to 3.67 mm on average (p<0.001). The reduction of diameter in the male group was 3.52 mm on average. The reduction of diameter in the female group was 3.32 mm on average. The reduction of diameter was 3.28 mm in the group below age 29, 3.88 mm in the 30∼39 age group, 3.39 mm in the 40∼49 age group, and 2.71 mm in the above 50 age group on average. Conclusions The MRI results suggest that lumbar herniated disc can resorb with Korean Medicine treatment. The likelihood of lumbar disc resorption was higher at extrusion type. but there was not a significant difference between the sexes and between ages. (J Korean Med Rehab 2016;26(1):87-93)

장애발생시기에 따른 삶의 만족도와 장애수용도와의 관계

간우선(Kan Woo-sun),조성재(Jo Song-jae),조주현(Cho Joo-hyun) 한국재활심리학회 2012 재활심리연구 Vol.19 No.1

본 연구는 장애발생시기에 따른 장애수용 및 삶의 만족도 간의 관계를 규명하는데 목적이 있으며 이 같은 목적을 달성하기 위해 전국 7개 광역시에 거주하고 있는 지체장애인을 대상으로 우편조사를 실시하였으며, 233부가 연구의 분석에 사용되었다. 연구결과를 살펴보면 첫째, 장애발생시기와 장애수용도 사이의 관계를 규명하기 위해 독립표본 t-검정을 사용하였으며, 그 결과 통계적으로 유의미한 관계가 있는 것으로 밝혀졌다. 즉 선천성과 후천성을 기준으로 한 장애발생시기가 개인이 획득하게 된 장애 수용 정도에 관계를 가진다는 것을 알 수 있다. 둘째, 장애발생시기와 장애수용도 사이에 관계를 규명하기 위해 독립표본 t-검정을 사용하였으며, 그 결과 통계적으로 유의미한 관계가 존재하지 않은 것으로 밝혀졌다. 이는 본 연구에서 정의한 삶의 만족도가 개인의 주관적 인지에 따른 것으로서 자신의 장애발생시기보다는 현재 본인의 사회환경적 요인에 더 많은 영향을 받을 수 있다는 점에서 기인한 것으로 추정된다. 이상의 연구결과를 바탕으로 장애발생시기를 고려한 맞춤화되고(customized) 개별화된(individualized) 직업재활 서비스제공 모델 개발을 위한 심도 있는 논의가 이루어져야 할 것이다. The purpose of this study is to examine the relationship of acceptance of disability and life satisfaction to the onset of disabilities among individuals with disabilities. Two-hundreds and thirty-three adults who are registered as having a physical disability residing in seven metropolitan cities in Korea participated in this study. A mail survey were used. A result of t-test indicated that a statistically significant relationship existed between the acceptance of disability and the onset of disabilities. That is, participants who experienced his or her disability at the earlier age of their lives are more likely to demonstrate more positive attitudes toward his or her disabilities as compared to their counterparts whose onset of disability were at later years of his/her life. However, no statistically significant relationship was found between the life satisfaction and the onset of disability. These findings suggested that an individualized vocational rehabilitation program which is based on the onset of disability as well as the level of acceptance of disability for individuals with physical disabilities are needed. Implications for the vocational rehabilitation practice and suggestions for the future research are discussed.

Nd:YAG 레이저를 이용한 애자 표면 염분 오손 측정장치에 관한 연구

權東震(Dong-Jin Kweon),鄭吉朝(Gil-Jo Jung),李弘植(Hong-Sik Lee),曺柱鉉(Joo-Hyun Cho) 대한전기학회 1998 전기학회논문지 Vol.47 No.11

추간판 장애 환자의 최근 3년간 진료경향 분석

고웅(Ung Go),정범환(Bum-Hwan Jung),조주현(Joo-Hyun Jo),김성문(Sung-Moon Kim),최승범(Seung-Peom Choi),정해찬(Hae-Chan Jeong),전용태(Yong-Tae Jeon) 대한스포츠한의학회 2014 대한스포츠한의학회지 Vol.14 No.2

Objectives This study aimed to analyze the clinical data of intervertebral disc disorder in Korea. Methods We use the statistics data of Health Insurance Review and Assessment Service from 2011 to 2013. All codes that corresponds to M51 below is limited to intervertebral disc disorder of this study. Kinds of disorder, number of patients and medical costs were analyzed. Only to the statistics of 2013, we analyzed different gender and age, the distribution of sub-classified disease (fourth‑character subdivisions). Result 4.1% of the total population had medical treatment with intervertebral disc disorder. Korean medicine is 0.4% and western medi-cine is 3.7%. The medical costs for both Korean medicine and western medicine treatment are increasing 1.26 and 1.12 times over 3 years, respectively. The number of patients for Korean medicine is decreasing 0.9 times and the number of patients for western medicine is increasing slowly. Total medical spent and total number of patients for Korean medicine are less than 10% compared to the western medicine. Analysis results in 2013, female patients showed a lot of distribution than male patients. By age, Korean medicine and western medicine showed different distribution. Korean medicine and western medicine all showed the highest distribution is M511, in the rest of the order was a difference. Conclusions This study, as a result of basic health insurance information analysis, has its meaning. It might be helpful to draw Korean medical treatment strategy for intervertebral disc disorder.