폐경기 여성에서 호르몬 보충요법과 활성형 비타민 D의 골밀도및 골전환표지자에 미치는 영향에 관한 연구

조동휘,조성환,어완규,김흥열 고신대학교 의학부 2003 高神大學校 醫學部 論文集 Vol.18 No.1

Background: The purposes of this study were to evaluate the effect of hormon replacement therapy & vitamin-D on the bone mineral density and bone metabolism in the postmenopausal women, and to compare the effect of vitamin D alone with those of premarine or premarin plus vitamin D. Method: 150 postmenopausal women were randomly submitted to the 3 groups of treatment with 0.5㎍ of vitamin D daily by oral administration (Group Ⅰ), 0.625㎎ of premarine once a day (Group Ⅱ), and 0.625㎎ of premarine once a day plus 0.5㎍ of vitamin D daily by oral administration (Group Ⅲ), In all subjects, bone mineral density (BMD) of lumbar spine and femur neck, urinary calcium/creatinine ratio, and serum osteocalcin were measured before treatment and after 6 and 12 months of treatment. Results: BMD of femur neck in Group Ⅰ, Group Ⅱ, and Group Ⅲ increased but not significantly compared to basal level at 6 months and/or 12 months of treatment. As for BMD of lumbar spine, it increased significantly during the treatment in Group Ⅱ and Group Ⅲ, but not in Group Ⅰ. Serum osteocalcin in Group Ⅱ and Group Ⅲ decreased significanly at 12 minths of treatment compared with Group Ⅰ. Urinary calcium/creatinine ratio & urine deoxypiridinoline in Group Ⅱ, Group Ⅲ, decreased significantly at 12 months of treatment compared with Group Ⅰ. Conclusion: From the above results, it might be suggested that combined therapy is more effective in post menopausal women with the protection on decreasing bone mineral density.

폐경기 여성에서 호르몬 보충요법과 활성형 비타민 D의 골밀도및 골전환표지자에 미치는 영향에 관한 연구

조동휘,조성환,어완규,김흥열 고신대학교(의대) 고신대학교 의과대학 학술지 2003 고신대학교 의과대학 학술지 Vol.18 No.1

Background The purposes of this study were to evaluate the effect of hormon replacement therapy & vitamin-D on the bone mineral density and bone metabolism in the postmenopausal women, and to compare the effect of vitamin D alone with those of premarine or premarin plus vitamin D. Method 150 postmenopausal women were randomly submitted to the 3 groups of treatment with 0.5㎍ of vitamin D daily by oral administration (Group I), 0.625mg of premarine once a day (Group II), and 0.625mg of premarine once a day plus 0.5㎍ of vitamin D daily by oral administration (Group III). In all subjects, bone mineral density (BMD) of lumbar spine and femur neck, urinary calcium/creatinine ratio, and serum osteocalcin were measured before treatment and after 6 and 12 months of treatment. Results BMD of femur neck in Group I, Group II and Group III increased but not significantly compared to basal level at 6 months and/or 12 months of treatment. As for BMD of lumbar spine, it increased significantly during the treatment in Group II and Group III, but not in Group I. Serum osteocalcin in Group II and Group III decreased significanly at 12 months of treatment compared with Group I. Urinary calcium/creatinine ratio & urine deoxypiridinoline in Group II, Group III, decreased significantly at 12 months of treatment compared with Group I. Conclusion From the above results, it might be suggested that combined therapy is more effective in post menopausal women with the protection on decreasing bone mineral density.

Multi-Functional Soft Composites for Safety-Engineering of Skin Interfaced Devices

Donghwi Cho(조동휘) 한국고분자학회 2022 한국고분자학회 학술대회 연구논문 초록집 Vol.47 No.1

만성기관지염 환자에서 중복유문 소견을 보인 위궤양 1예

임영찬,한병호,조동휘,홍재락,전태희,임홍섭,심영웅,송갑영 대한소화기내시경학회 2002 Clinical Endoscopy Vol.25 No.2

The double pylorus is a fistulous communication between gastric antrum and duodenal bulb. It appears to be an acquired lesion in the majority of cases. Upon routine endoscopic procedures, it is frequently seem to occur in males who are either alcoholics, diabetics, those with chronic renal failure, chronic lung disease. If it is no developing complications such as septal rupture, double pylorus is well response to medical treatment. A 51-year-old man who had been taking medication over a long period for the chronic bronchitis was admitted to this hospital because of epigastric soreness and indigestion for 1 month. Endosopic findings showed two large openings of the pyloric channel and gastric ulcer in the channel. We thought that this case was an acquired lesion reasult of repeated gastric ulcer. We report a case of double pylrous with the brief review of literatures. (Korean J Gastrointest Endosc 2002;25:89-91) 중복유문은 원위전정부와 십이지장을 연결하는 유문륜이 두 개로 이루어진 드문 위장관 기형으로 주로 위 소만과 십이지장 구부의 상부에서 발생한다. 중복유문의 발생은 궤양에 의한 이차적인 경우와 발생학적으로 게실이나 낭종에 의해 생길 수 있다. 검진 내시경에서 남자에게 빈발하고 알코올 중독, 당뇨, 만성 신부전, 만성 폐질환 등의 기저질환을 동반한 경우가 흔하다. 대부분의 환자에서 궤양의 병력이 있으나 중복유문의 증상은 경미하며, 격막 파열과 같은 합병증이 없다면 유문의 변형에도 불구하고 내과적 치료에 잘 반응한다. 저자들은 만성 기관지염으로 장기간 약물 복용을 하던 51세 남자 환자의 내시경 검사에서 위궤양에 동반된 중복유문 소견을 보인 1예를 경험하였으며, Helicobactoer pylori 제균과 궤양치료로 소화장애 증상이 완화되었다. 환자는 만성 기관지염에 대한 약물치료를 계속하면서 중복유문에 의한 합병증 및 궤양 재발에 대해 경과 관찰 중이다.

Long-Term Outcome of Internal Mammary Lymph Node Detected by Lymphoscintigraphy in Early Breast Cancer

구민영,이세경,배수연,최민영,조동휘,김상민,이정언,남석진,양정현 한국유방암학회 2012 Journal of breast cancer Vol.15 No.1

Purpose: Internal mammary lymph node (IMLN) metastasis is an important prognostic indicator in breast cancer. However, the necessity of internal mammary sentinel lymph node biopsy for accurate staging, for choosing adjuvant treatment, and as a prognostic indicator, has remained controversial. Methods: From January 2001 to December 2006, 525 female breast cancer patients underwent radical surgery after preoperative lymphatic scintigraphy. We retrospectively analyzed the follow-up results, recurrences, and deaths of all patients. Results: There was no significant difference in the clinicopathological characteristics between the axilla and the IMLN groups. The median follow-up period was 118.8 months (range, 7-122 months) in the axilla group and 107.7 months (range, 14-108 months) in the IMLN group. During the median follow-up period, the breast cancerrelated death rate in the axilla group was 3.6%, which was not significantly different from that of the IMLN group (1.3%) (p=0.484). The five-year survival rates did not differ between the two groups (p=0.306). The overall recurrence rate and the locoregional recurrence rate also did not differ between the two groups (p=0.835 and p=0.582, respectively). The recurrence rate of IMLN (both ipsilateral and contralateral) metastasis was very low, accounting for 0.5% in the axilla group and 1.3% in the IMLN group (p=0.416). Conclusion: The long-term follow-up results showed that there was no significant difference in both overall outcome and regional recurrence between the two groups. Therefore, the requirement for identification of nodal basins outside the axilla or IMLN sentinel biopsy should be reconsidered.

십이지장 구부에 발생한 심재성 낭종성 장염 1예

장희종,정재일,김명찬,조동휘,조동식,이상훈,김시우,차성철,조유진,석윤철,기승석,강행지 대한소화기내시경학회 2005 Clinical Endoscopy Vol.31 No.6

Enteritis cystica profunda (ECP) is characterized by mucin-filled cystic spaces that are partially lined by non-neoplastic columnar epithelium, and these are found in the wall of the small bowel. This is a very rare disease compared to cystica profunda involving the stomach or colon. The cause of ECP is still unclear. Most ECP is related to or it may accompany other intestinal diseases. We encountered one case of ECP of the duodenal bulb that presented as polyp, and this was not related to adenocarcinoma or any other intestinal diseases like Crohn's disease or ulcerative colitis. Endoscopic polypectomy was done and the ECP was later confirmed through histological evaluation. 심재성 낭종성 장염(enteritis cystica profunda, ECP)은 매우 드문 질환으로 성숙된 선상피가 점막하층까지 침윤하여 낭종을 형성하며 대부분 동반질환이 있는 것으로 알려졌다. 저자들은 고혈압 외에 특별한 질병 없이 건강히 지내던 환자에서 우연히 발견된, 십이지장 구부에 용종 형태로 발병한 ECP 1예를 경험하였기에 보고하는 바이다.

흉막염과 간염이 합병된 장티푸스

한병호 ( Han Byeong Ho ),조동휘 ( Jo Dong Hwi ),전태희 ( Jeon Tae Hui ),주기중 ( Ju Gi Jung ),이중건 ( Lee Jung Geon ),이종수 ( Lee Jong Su ),송갑영 ( Song Gab Yeong ) 대한내과학회 2003 대한내과학회지 증례 특집호 65-5 부록3 Vol.0 No.-

Typhoid fever often manifests hepatic involvement but pleural involvement has rarely been reported to occur as a complication of typhoid fever. One case of typhoid pleurisy, in which Salmonella was isolated from the blood, is presented with the brief revi

CNN 기반의 실사 이미지에 대한 게임 그래픽과 AI 그림 분류 모델 개발

박승보(Seung-Bo Park),조동휘(Dong-Hwi Cho),최서영(Seo-Young Choi),김은지(Eun-Ji Kim) 한국컴퓨터정보학회 2023 한국컴퓨터정보학회 학술발표논문집 Vol.31 No.2

A Case of IgG4-Related Lung Disease Presenting as Interstitial Lung Disease

안재환,송진우,홍선인,조동휘,채은진,송준선 대한결핵및호흡기학회 2014 Tuberculosis and Respiratory Diseases Vol.77 No.2

Intrathoracic involvement of immunoglobulin G4 (IgG4)-related disease has recently been reported. However, a subset of the disease presenting as interstitial lung disease is rare. Here, we report a case of a 35-year-old man with IgG4-related lung disease with manifestations similar to those of interstitial lung disease. Chest computed tomography showed diffuse ground glass opacities and rapidly progressive pleural and subpleural fibrosis in both upper lobes. Histological findings showed diffuse interstitial lymphoplasmacytic infiltration with an increased number of IgG4-positive plasma cells. Serum levels of IgG and IgG4 were also increased. The patient was diagnosed with IgG4-related lung disease, treated with anti-inflammatory agents, and showed improvement. Lung involvement of IgG4-related disease can present as interstitial lung disease and, therefore, should be differentiated when evaluating interstitial lung disease.

Clinical Correlation between Gastric Cancer Type and Serum Selenium and Zinc Levels

지재효,신동규,권유진,조동휘,이경복,박상수 대한위암학회 2012 Journal of gastric cancer Vol.12 No.4

Purpose: We conducted this study to study the clinical correlation between the characteristics of gastric cancer and serum selenium and zinc levels. Materials and Methods: The following data were measured in the baseline serum selenium and zinc levels of 74 patients with curative gastrectomy subsequent to confirmed gastric cancer, from March 2005 to August 2012. Results: Among the 74 gastric cancer patients, 53 patients were male. Mean serum selenium and zinc levels were 118.7±33.1 ug/L and 72.2±24.3 ug/dl, respectively. Seven patients (9.5%) showed lower selenium level, and 33 patients (44.6%) showed lower zinc level. Serum Selenium level was 99.1±31.8 ug/L in cardia cancer group (10 cases) and 121.8±32.4 ug/L in non-cardia cancer group (64 cases)(P=0.044). According to tumor gross type, zinc level was 78.7±29.6 ug/dl in early gastric cancer (33) and 66.9±17.8 ug/dl in advanced gastric cancer (41) (P=0.064). Conclusions: The serum selenium level was highly correlated with the location of gastric cancer. The serum zinc level was lower in advanced gastric cancer.