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웅담(熊膽) 및 우루소데옥시콜린 산(酸)의 항(抗)알레르기 효과(效果)에 관(關)한 실험적(實驗的) 연구(硏究)
정재환,이진용,김덕곤,정규만,Jeong Jae-Hwan,Lee Jin-Yong,Kim Deok-Gon,Jeong Gyu-Man 대한한방소아과학회 1996 대한한방소아과학회지 Vol.10 No.1
Experimental studies were done to research the effects of the Ursi fel and the UDCA on the anti-allergic effects. The results were obtained as follows: 1) In the experimental effects of the Ursi fel and the UDCA on the vascular permeability responses to intradermal Serotonin, though both of the Ursi fel and UDCA revealed the significant effect, the Ursi fel had stronger effect than the UDCA. 2) In the provocative effects of the Ursi fel and the UDCA on the vascular permeability responses to intradermal Histamin, though both of the Ursi powfel and UDCA showed the significant effect, the Ursi fel had moreerful effect than the UDCA. 3) In the 48 hours homologous passive cutaneous anaphylaxis provoked by the IgE-like antibody against white egg albumin, though both of the Ursi fel and UDCA revealed significant effect, the Ursi fel had stronger effect than the UDCA. 4) In the delayed type hypersensitivity response to Picryl Chlorede, though both of the Ursi fel and UDCA were proved to be effective significantly the Ursi fel showed stronger effect. 5) In the delayed type hypersensitivity responses to Sheep red blood cell, the Ursi fel revealed the significant effect, though the UDCA has no significant effect. According to above results, the Ursi fel was approved it could be used widely as antiallergic drug for immediate and delayed type allergic diseases. Although the UDCA revealed efficacy in immediated type allergic diseases, it had less powerful effects than the Ursi fel and it showed no effects in some experiment of delayed type allergy, so it would be difficult to be used clinically.
정재환,윤호영,정창순,김경섭,Jung, Jae Hwan,Yun, Ho Yeong,Jeong, Chang Soon,Kim, Kyung Sup 한국재난정보학회 2018 한국재난정보학회 논문집 Vol.14 No.2
Purpose: This research proposes an optimization model for effective evacuation routing and scheduling of civilians near the border area when full-scale war threats heighten. Method: To reflect the reality, administrative unit network is created using Kruscal's Algorithm, Harmony Search, CCRP based on the geographical features, population, and traffic data of real cities, and then, optimal civilian evacuation routes are found. Results: Optimal evacuation routes and schedules are computed by repetitive experiments, and it is found that the scenario that minimizes the average civilian evacuation time is effective for the civilian evacuation plan. Conclusion: By using the civilian evacuation plan this research proposes, at the time of establishing the actual civilian evacuation plan, quantitative analysis is used for the effective plan making rather than only depending. 연구목적: 본 연구는 전면전 위기 고조 시 효율적인 접경지역 주민 철수경로 및 일정수립에 최적화된 모형 제안을 목적으로 한다. 연구방법: 현실 반영을 위해 실제 도시의 지형, 인구, 도로 데이터를 기반으로 Kruscal's Algorithm, Harmony Search, CCRP를 활용하여 행정구역(읍 면 동) 단위 네트워크를 생성한 후, 최적의 주민철수로를 찾는 순서로 실험을 진행한다. 연구결과: 반복실험을 통해 최적의 주민철수 경로 및 스케줄을 산출하였고, 주민 철수시간 평균을 최소화하는 시나리오가 주민철수 계획수립에 효율적이라는 것을 확인하였다. 결론: 본 연구에서 제안하는 주민철수 모형을 활용하면, 주민철수 계획 수립 시 기존의 정성적인 분석에 정량적 분석을 보완하여 보다 효율적인 계획 수립이 가능할 것으로 사료된다.