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Paper-Based Analytical Device for Quantitative Urinalysis
정성근,김종민,남진오,송영신,이창수 대한배뇨장애요실금학회 2013 International Neurourology Journal Vol.17 No.4
Paper-based analytical devices are fluidic chips fabricated with extremely inexpensive materials, namely paper, thereby allowing their use as a zero-cost analytical device in third-world countries that lack access to expensive diagnostic infrastructures. The aim of this review is to discuss: (1) microfluidic paper-based analytical devices (μPADs) for quantitative analysis, (2) fabrication of two- or three-dimensional μPADs, (3) analytical methods of μPADs, and (4) our opinions regarding the future applications of μPADs for quantitative urinalysis.
2LO-9 Multiplexed digital assay in a three-dimensional paper-based microfluidic analytical device
정성근,진시형,이병진,심규락,김동영,강소립,이창수 한국공업화학회 2017 한국공업화학회 연구논문 초록집 Vol.2017 No.1
Here, we demonstrate 3-dimensional (3D) paper-based microfluidic channels to control 3D flow for automatic multiplexed digital assay. The 3D channels were fabricated by double-sided printing and lamination process. We print and laminate asymmetrical and symmetrical wax patterns on the paper to form 3D channels, and to create 3D fluidic flow for multiplexed digital assay. The 3D channels contains lateral and vertical channel. The asymmetrical wax-patterns form lateral and vertical channels. The symmetrical wax-patterns form vertical channels when the melted wax make contact with each other. We injected red dye into inlet of channels to track 3D capillary flow in the 3D channel. We conformed that the 3D fluid flow in a thickness of a paper. Based on this concept, we created 3D devices for automatic digital assay to detect glucose and albumin. Therefore, we expect that this method could be an instrument-free and multiplexed assay format for use in developing countries.