대한갑상선학회 갑상선분화암 진료권고안; Part III. 진행성 갑상선분화암의 치료 - 제5장 진행성 갑상선분화암 전이 병소의 부위별 치료 원칙 2024

정경연 대한갑상선학회 2024 International Journal of Thyroidology Vol.17 No.1

Only a small percentage of patients (2-5%) with differentiated thyroid cancer (DTC) exhibit distant metastasis at the initial diagnosis or during the disease course. The most common metastatic sites of DTC are the lungs, followed by the bones. Radioactive iodine (RAI) therapy is considered the primary treatment for RAI-avid distant metastatic DTC. Depending on the characteristics of metastatic lesions, local treatment such as surgical resection, radiofrequency ablation, and external beam radiation therapy may be considered for some patients with metastatic DTC. Slowly growing and asymptomatic metastases can be monitored with follow-up while receiving thyroid-stimulating hormone (TSH) suppression therapy. In patients with a limited number of lung metastases and good performance status, surgical removal of the metastatic lesions may be considered. Systemic therapy should be considered for patients with progressive RAI refractory DTC. In this clinical guideline, we aim to outline the treatment principles for patients with lung, bone, and brain metastases of DTC.

다문화 시민성 형성을 위한 초등 사회과 수업안 개발 및 적용 : 국정교과서 6학년 2학기 ‘세계 여러 지역의 자연과 문화’ 단원을 중심으로

정경연,황수경 한국인격교육학회 2014 인격교육 Vol.8 No.1

The purpose of this paper is to develop and apply teaching-learning course plan for the formation of multicultural citizenship in elementary social studies focused on the unit “Nature and culture of many parts in the world” of the national textbook for sixth grade, second semester in elementary social studies. For this purpose, we examined the concept of multicultural citizenship and extracted three lower elements of multicultural citizenship. On the basis of this, we analyzed the 2009 revised curriculum of elementary social studies and developed interview materials concerning the concept of multiculturalism and three lower elements of multicultural citizenship through cooperative action research and taught class in applying teaching-learning course plan during three weeks. We interviewed in advance and after the development of data, and before and after the application of teaching-learning course plan in order to gauge the multicultural citizenship formation. Form this research, thought process and attitude of elementary school students toward subject of study changed and we gauged formation of multicultural citizenship. This paper proposes the action-based research method for elementary school teachers through development and application of elementary social studies teaching-learning course plan to form multicultural citizenship at schools. 이 연구의 목적은 국정교과서 6학년 2학기 초등 사회과 ‘세계 여러 지역의 자연과 문화’ 단원을 중심으로 사회과 수업에서 다문화 시민성을 형성할 수 있도록 다문화교육 수업안을 개발하여 적용하는 것이다. 이를 위해 다문화 시민성의 개념을 검토하고 다문화 시민성의 하위 요소 세 가지를 추출하였다. 이를 바탕으로 2009 초등 사회과 교육과정을 분석하고, 협동적 실행 연구를 통해 다문화의 개념과 다문화 시민성의 하위 요소 세 가지에 대한 인터뷰 자료와 3차시의 수업안을 개발하였으며, 3주에 걸쳐 수업안을 적용하여 수업으로 구현하였다. 다문화 시민성 형성의 변화를 알아보기 위해 개발한 인터뷰 자료를 가지고 수업안의 적용 전과 후에 사전 인터뷰와 사후 인터뷰를 실시하였다. 수업안의 적용 결과는 전과 후를 비교·분석하여 그 결과를 질적으로 해석하였다. 이 연구 결과 연구대상 초등학생들의 생각과 태도에 변화가 있는 것으로 나타나 다문화 시민성이 형성되어가는 것을 확인할 수 있었다. 이 논문은 학교 현장에서 다문화 시민성을 형성할 수 있는 초등 사회과 수업안을 개발·적용함으로써 초등학교 교사들에게 하나의 실행 연구 방법을 제시하고 있다.

베이징 국제 섬유비엔날레에 관한 연구 -한국, 중국, 일본의 출품작을 중심으로-

정경연,윤나영 한국패션비즈니스학회 2020 패션 비즈니스 Vol.24 No.3

This paper is a study of culture and identity expressed in textile art works of the age of globalization, centering on the Beijing International Fiber Art Biennale. This study began with the idea that globalism would develop regional cultural diversity as well as contribute to the field of art. In 2000, the Beijing International Fiber Art Biennale held its first large exhibition, and a total of 10 biennales were held from then until 2018. Get an understanding of the Beijing International fiber art Biennale, and select award-winning works from one to ten times to learn about cultural characteristics and identity. The analysis was based on the works of awards from China and Japan, including Korea, which are the center of East Asian culture. The Beijing International Fiber Art Biennale has steadily increased the number of participating countries, writers and works, and once again opened the stage for the revival of textile art following the Lausanne International Tapestry Biennale. Through the Beijing International Fiber Art Biennale, textile artists hope to promote world harmony in textile art, respect cultural diversity and conduct equal dialogue between East and West cultures.

위생.안전.건강 - Yellow food로 성인병을 예방하자

정경연,Jeong, Gyeong-Yeon 한국식품연구원 2008 한맛한얼 Vol.1 No.3

루이즈 부르주아 바느질 작품 연구-섬유인체조각을 중심으로-

정경연,김혜란 사단법인 한국조형디자인협회 2008 조형디자인연구 Vol.11 No.2

The study examines what needlework represents and symbolizes as a non-artistic technique in the contemporary art. Firstly, the study explores work of Louise Bourgeois (1911~). Since the 1930s, she has produced artwork in various genres including painting, printing, sculpture, installation work and textile sculpture, all with consistent theme of creation. When an artist shows distinct changes in using materials and methods who had worked with the same theme for a long time, we can interpret it as a new attempt or change in the artist's philosophy. It deserves our attention to see how Bourgeois used to mainly produce large-scale installation work made of bronze mold and marble pieces, but began to produce a series of textile sculpture figures since the mid-1990s, made of old fabric and clothes, which she employed only as part of objets in the installation work before. The study analyzes symbolic meaning of severed body parts and needlework in Bourgeois's work, examines its relation with the tradition of expressing severed body parts that has been present in modern and contemporary Western art to clarify the context of Bourgeois's work.

A Case of Acute Myocardial Infarction With ST-Segment Elevation in a Lead Augmented Right Vector Caused by a Left Main Coronary Artery Vasospasm

정경연,강태수 대한심장학회 2012 Korean Circulation Journal Vol.42 No.1

Diagnosing and selecting an appropriate treatment strategy for left main coronary artery (LMCA) obstruction is very important. Although this disease is not frequently encountered, it can cause severe hemodynamic deterioration resulting in a less favorable prognosis without a suitable management approach. Another aspect of LMCA that we must not overlook is coronary artery spasm, which can be an infrequent but important cause of acute coronary syndrome. Although it is rare, LMCA can cause critical complications. In this study, we report the case of a 35-year-old female who was admitted to the hospital with a diagnosis of acute myocardial infarction with ST-segment elevation in the aVR lead caused by a left main coronary spasm that was examined on intravascular ultrasound.

Reversible Heart Failure and Rhabdomyolysis Caused by Primary Hypoparathyroidism during Lactation

정경연,최정현,김희진,정현경,김도희 대한내분비학회 2011 Endocrinology and metabolism Vol.26 No.3

Hypocalcemia can be complicated, on rare occasions, by congestive heart failure and may also be associated with labor and lactation in some cases. Herein, we report a 30-year-old woman with hypocalcemia-induced heart failure secondary to primary idiopathic hypoparathyroidism precipitated by lactation. The patient presented with chest pain and paresthesia in both arms and legs during breast-feeding after her second delivery. She had severe hypocalcemia and low parathyroid hormone levels. Hypocalcemiainduced rhabdomyolysis further aggravated her hypocalcemia symptoms. The echocardiogram showed global hypokinesia with an ejection fraction of 47%. After calcium and vitamin D replacement, her symptoms and ventricular function improved. Hypocalcemia needs to be considered in patients with heart failure, because it is readily reversible. To the best of our knowledge, this is the first report of a patient with heart failure and rhabdomyolysis induced by primary hypoparathyroidism during lactation.

Therapeutic Approaches for Preserving or Restoring Pancreatic β-Cell Function and Mass

정경연,김경민,임수 대한당뇨병학회 2014 Diabetes and Metabolism Journal Vol.38 No.6

The goal for the treatment of patients with diabetes has today shifted from merely reducing glucose concentrations to preventing the natural decline in β-cell function and delay the progression of disease. Pancreatic β-cell dysfunction and decreased β-cell mass are crucial in the development of diabetes. The β-cell defects are the main pathogenesis in patients with type 1 diabetes and are associated with type 2 diabetes as the disease progresses. Recent studies suggest that human pancreatic β-cells have a capacity for increased proliferation according to increased demands for insulin. In humans, β-cell mass has been shown to increase in patients showing insulin-resistance states such as obesity or in pregnancy. This capacity might be useful for identifying new therapeutic strategies to reestablish a functional β-cell mass. In this context, therapeutic approaches designed to increase β-cell mass might prove a significant way to manage diabetes and prevent its progression. This review describes the various β-cell defects that appear in patients with diabetes and outline the mechanisms of β-cell failure. We also review common methods for assessing β-cell function and mass and methodological limitations in vivo. Finally, we discuss the current therapeutic approaches to improve β-cell function and increase β-cell mass.

부모의 자아분화수준에 따른 아동의 자아분화와 아동이 wl각한 세대간 가족관계

정경연,심혜숙 한국가족치료학회 2007 가족과 가족치료 Vol.15 No.2

Intergenerational Relationships and Self-Differentiation Kyoung-Yeon Joung (Bu-Am Elementary School) Hae-Sook Sim (Pusan National University) A sample of 620 children from fifth and the sixth grades in six elementary schools in Pusan City participated, along with their parents, in a study of intergenerational family relationships and self-differentiation. Instruments for measuring intergenerational family relationships and the parents' and children's self-differentiation levels were translated into Korean and adapted for the study. The data, analyzed using t-tests and MANCOVA, revealed meaningful differencesin the following areas: 1) between the self-differentiation of the boys and girls and between the fathers and mothers; 2) between the parent's and the children's self-differentiation levels; 3) between the parent's self-differentiation level and the intergenerational family relationship, as perceived by the children. ●본 연구는 부모 자아분화 수준에 따른 아동 자아분화 수준과 아동이 지각한 세대간 가족관계의 관련성을 알아보고자 하였다. 연구대상자는 부산시내 6개의 초등학교 5,6학년 620명의 아동과 그 부모를 대상으로 하였다. 아동에게는 아동용 자아분화 검사, 세대간 가족관계 검사를 실시하였으며, 부모에게는 부모용 자아분화 검사를 실시하였다. 자료 분석은 t-test와 아동의 성별을 공변인으로 두고 MANCOVA를 실시하였으며, Scheffe 사후검증을 사용하였다. 본 연구의 결과는 첫째, 아동 자아분화는 성별에 따라 차이가 있었으며, 남학생의 자아분화가 여학생의 자아분화보다 높았다. 둘째, 부 자아분화와 모 자아분화는 유의미한 차이가 있었으며, 부의 자아분화가 모의 자아분화보다 높은 것으로 나타났다. 셋째, 부모 자아분화 수준의 부모조합에 따른 아동의 자아분화는 유의미한 차이가 있었다. 부의 자아분화가 낮고 모의 자아분화가 높은 집단의 아동이 다른 3집단의 아동보다 자아분화가 높았다. 넷째, 부모 자아분화 수준의 부모조합에 따른 아동이 지각한 세대간 가족관계는 유의미한 차이가 있었다. 부모의 자아분화 수준이 모두 높은 집단의 아동이 부모의 자아분화 수준이 모두 낮은 집단의 아동보다 부모-자녀사이의 세대간 친밀이 높았다. 하지만, 부모 자아분화 수준이 모두 높은 집단의 세대간 간섭이 오히려 높고 세대간 융합 수준이 높은 것으로 나타났다. 본 연구는 부모의 자아분화 수준에 따른 아동의 자아분화와 부모-자녀간의 세대간 가족관계의 패턴을 파악한데 그 의의가 있다고 하겠다.

우황(牛黃)·웅담(熊膽)·사향(麝香) 복합제제(複合製劑) 약침자극(藥鍼刺戟)이 LPS유발(誘發) 관절염(關節炎)의 면역반응(免疫反應)에 미치는 영향(影響)

정경연,김갑성,윤종화,Jeong, Kyung-Yeon,Kim, Kap-Sung,Yoon, Jong-Hwa 대한침구의학회 2001 대한침구의학회지 Vol.18 No.1

Objective : To investigate the effect of BUM aqua-acupuncture in treating the RA, the immunosis to logical analysis of LPS induced arthritis in mice to study this. For 14th day after the injection of LPS & BUM injection, the distribution of fibroblast, collagen, CD54(ICAM-1), CD106(VCAM-1), IL-$1{\beta}$, IL-2 receptor, CDl lb(macrophage) were examined on synovial capsule of mice knee joint. For 14th day after the injection of LPS & BUM injection, the distribucion of CD4(TH cell), CD8(TC cell), CD40(B cell) were examined on common iliac lymph node in mice. Methods : The experimental model of arthritis was induced by injection of 300${\mu}g$/kg LPS in BALB/c mice weighing 30g. The 100${\mu}l$ BUM aqua-acupuncture which compounded calculus bovis, fel ursi and moschus was injected into GB34 of mice every other day for 12 days. For 3rd, 7th, 14th day after the injection of LPS, the neutrophil, lymphocyte and monocytc counts in WBC were measured using hemacytometer. Results : The obstain results are summarized as follows ; 1. In sample group, the neutrophils counts were increased and the lympnocytes counts were decreased compared with control group. 2. The distribution of fibrosis & fibroblast on synovial membrane were decreased compared with control group. 3. The distribution of collagen fiber on synovial membrane were decreased compared' with control group. 4. The distribution of CD54(ICAM-1) & CD106(VCAM-1) on synovial membrane were decreased compared with control group. 5. The distribution of IL-$1{\beta}$ & IL-2 receptor on synovial membrane were decreased compared with control group. 6. The distribution of CDb(macrophage) on synovial membrane were decreased compared with control group. 7. The distribution of CD4(TH cell), CD8(TC cell) and CD40(B cell) in common iliac lymph nodes were decreased compared with control group. Conclusions : BUM aqua-acupuncture stimulation decreased inflammatory responses LPS induced arthritis in mice.