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무산소운동이 혈중 백혈구수, 호중구 활성산소종 생성 및 젖산농도에 미치는 영향
이호성 한국운동생리학회(구 한국운동과학회) 2012 운동과학 Vol.21 No.2
이호성. 무산소운동이 혈중 백혈구수, 호중구 활성산소종 생성 및 젖산농도에 미치는 영향. 운동과학, 제21권 제2호,263-270, 2012. 이 연구의 목적은 무산소운동이 백혈구수, 호중구 ROS 생성 및 젖산농도에 미치는 영향에 대해 검토하였다. 일반 성인남자 10명을 연구대상으로 하였으며, 무산소운동은 자전거 에르고미터를 이용하여 체중 당 부하강도 0.075 kp로서10초간 전력 페달링 운동을 50초간의 휴식시간을 두고 연속적으로 5회 실시하였다. 백혈구수, 호중구 ROS 생성, 호중구 대비ROS 생성, 적혈구수, 호중구수, 간상핵구수, 분엽핵구수, 혈색소양, 헤마토크리트, 평균 혈구용적치 및 젖산은 무산소운동전및 직후, 운동 30분, 60분 및 120분후에 각각 측정하였다. 백혈구수 및 호중구 대비 ROS 생성은 운동전과 비교해서 운동직후(p=.038) 및 운동 120분후에 유의하게 증가하였다(p=.035, p=.027 respectively). 호중구수(p=.029), 간상핵구수(p=.029), 분엽핵구수(p=.032) 및 호중구 ROS 생성은 운동전과 비교해서 운동 120분후에 유의하게 증가하였다(p=.039). 혈중 젖산농도는 운동전과 비교해서 운동직후(p=.021) 및 운동 30후(p=.041)에 유의하게 증가하였다. 이상의 결과, 이 연구에서는 단시간고강도의 무산소운동에 있어서도 호중구 ROS 생성이 증가한다는 것을 확인하였다. Lee, H. S. Effects of anaerobic exercise on circulating leukocytes, reactive oxygen species production in neutrophilis and lactate concentration in human. Exercise Science, 21(2): 263-270, 2012. The purpose of this study was to investigate the effects of anaerobic exercise on circulating leukocytes, reactive oxygen species production in neutrophilis and lactate concentration in human. All subjects (n=10) was performed cycle ergometer anaerobic exercise (10 seconds . 5 sets, rest for 50 seconds between each set) at load intensity 0.075 kp per weight. Changes in circulating leukocyte numbers, reactive oxygen species (ROS) production in neutrophilis, ROS per neutrophilis, red blood cell, neutrophilis, band form, segmented leukocyte, Hb, Hct, MCV and lactic acid was measured before, immediately after, 30, 60 and 120 minutes after the cycle ergometer anaerobic exercise. circulating leukocyte number and reactive oxygen species production per neutrophilis were significantly increased immediately after (p=.038) and after 120 minutes of anaerobic exercise (p=.035, p=.027 respectively) compared with before anaerobic exercise. Neutrophilis (p=.029), band form (p=.029), segmented leukocyte (p=.032), and reactive oxygen species production in neutrophilis were significantly increased after 120 minutes (p=.039) of anaerobic exercise compared with before anaerobic exercise. Lactic acid was significantly increased immediately after (p=.021) and after 30 minutes (p=.041) of anaerobic exercise compared with before anaerobic exercise. These results confirmed that anaerobic exercise increase reactive oxygen species production in neutrophilis.
이호성,Se-Whan Lee,Young Kyu Jung,Ung Jeon,박상호,Seung Jin Lee,Won-Yong Sin,Dong-Kyu Jin 대한심장학회 2013 Korean Circulation Journal Vol.43 No.8
The etiology and pathophysiology of takotsubo cardiomyopathy have not yet been fully clarified. We report a case of takotsubo cardio -myopathy associated with severe hypocalcemia secondary to hypoparathyroidism. A 69-year-old woman presented with acute pulmonary edema caused by severe left ventricular dysfunction with apical ballooning compatible with takotsubo cardiomyopathy. Laboratory tests revealed severe hypocalcemia secondary to idiopathic hypoparathyroidism. Coronary angiography showed normal coronary artery func-tion. Her symptoms and signs of heart failure improved dramatically with the correction of hypocalcemia through calcium and calcitriol replacement.
보조생식술을 시행한 난임환자에서의 뜸 치료에 대한 체계적 문헌고찰 및 메타분석
이호성,박용덕,이혜정,황덕상,장준복,이창훈,이진무,김동일 대한한방부인과학회 2022 大韓韓方婦人科學會誌 Vol.35 No.2
Objectives: The purpose of this study is to investigate the effectiveness of moxibustion in infertility with In Vitro Fertilization and Embryo Transfer (IVF-ET). Methods: We searched 8 databases (Embase, PubMed, CiNii, CNKI, OASIS, ScienceOn, KMBASE, KISS)to identify eligible studies published before 2021 Oct. We included randomized controlled clinical trials (RCTs) using moxibustion in infertility with IVF-ET. The methodological quality of each RCT was assessed by the Cochrane risk of bias tool. Results: Two RCT studies were eligible in our review. The overall risk of bias was evaluated as unclear. The meta-analysis of 2 trials indicated that favorable results for the use of moxibustion with IVF-ET. Conclusions: This systematic review and meta-analysis of clinical trials suggests that moxibustion with IVF-ET can effect on Infertility patients. However, because of studies included analysis was biased due to unclear risk of bias and unreliable study design, future RCT studies and additional Meta-Analysis are needed to judge the supplementary treatment role of moxibustion in infertility with IVF-ET.