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      • KCI등재후보

        노신과 이광수의 유학체험과 소설의 형상화 비교연구

        이호규,권혁건 대한중국학회 2009 중국학 Vol.32 No.-

        Lee Gwang Soo (1892~?) and Noh Shin (1881~1936) were representative modern Korean and Chinese authors and thinkers, each. The two people were common in having a studying abroad experience in Japan, and the period is also the same as it was around the mid~to~later 1900s. In this regard, comparing and reviewing their studying abroad experience as well as the formation of the experience foremost, based on their common points of studying abroad in Japan, becomes an important job in a discourse about modern eastern Asia. When conducting a comparative analysis of their study abroad experience and novels, focusing on their studying abroad and educational environments, interpersonal relationships, and its formation, as for Lee Gwang Soo, he reveals his experience and view of love along with humanitarianism and romanticism under the influence of Christianity and Tolstoi, whereas Noh Shin appeared to be directed to revolution, anti~feudality, and modern medicine with his tendency toward nationalism. When analyzing them from the perspective of tradition and modernity, Lee Gwang Soo was shown to aspire to free love and to create individual character on the basis of the Jeongnyuk theory(cultivation of emotion), along with a strong sense of resistance to early marriage. Meanwhile, Noh Shin clearly demonstrated a critical spirit in his works against Chinese tradition, represented as Chinese queue, and strong anti~feudal spirit describing Chinese history as the history of cannibalism, figuratively. Both the authors, Noh Shin and Lee Gwang Soo, aimed to advance in literature during their studying abroad, and they wanted to become literary men dedicated to their peoples through literature. The need for research into the common destiny and the situation of the times of the two people, who were representative intellectuals and literary men in modern Korean and China, respectively, is again being made evident.

      • KCI등재

        Association between Non-Alcoholic Steatohepatitis and Left Ventricular Diastolic Dysfunction in Type 2 Diabetes Mellitus

        이호규,김규리,최영주,허병욱,이병완,강은석,차봉수,이은직,이용호,허갑범 대한당뇨병학회 2020 Diabetes and Metabolism Journal Vol.44 No.2

        Background: Impaired diastolic heart function has been observed in persons with non-alcoholic fatty liver disease (NAFLD) and/or with type 2 diabetes mellitus (T2DM). However, it is unclear whether NAFLD fibrotic progression, i.e., non-alcoholic steatohepatitis, poses an independent risk for diastolic dysfunction in T2DM. We investigated the association between liver fibrosis and left ventricular (LV) diastolic dysfunction in T2DM. Methods: We analyzed 606 patients with T2DM, aged ≥50 years, who had undergone liver ultrasonography and pulsed-wave Doppler echocardiography. Insulin sensitivity was measured by short insulin tolerance test. Presence of NAFLD and/or advanced liver fibrosis was determined by abdominal ultrasonography and NAFLD fibrosis score (NFS). LV diastolic dysfunction was defined according to transmitral peak early to late ventricular filling (E/A) ratio and deceleration time, using echocardiography. Results: LV diastolic dysfunction was significantly more prevalent in the NAFLD versus non-NAFLD group (59.7% vs. 49.0%, P=0.011). When NAFLD was stratified by NFS, subjects with advanced liver fibrosis exhibited a higher prevalence of diastolic dysfunction (49.0%, 50.7%, 61.8%; none, simple steatosis, advanced fibrosis, respectively; P for trend=0.003). In multivariable logistic regression, liver fibrosis was independently associated with diastolic dysfunction (odds ratio [OR], 1.58; 95% confidence interval [CI], 1.07 to 2.34; P=0.022) after adjusting for insulin resistance and cardiometabolic risk factors. This association remained significant in patients without insulin resistance (OR, 4.32; 95% CI, 1.73 to 11.51; P=0.002). Conclusions: Liver fibrosis was associated with LV diastolic dysfunction in patients with T2DM and may be an independent risk factor for diastolic dysfunction, especially in patients without systemic insulin resistance.

      • KCI등재후보

        수지운동자극을 사용한 부운동중추의 기능적 MR연구: 일차운동중추와의 비교

        이호규,김진서,최충곤,임태환 대한자기공명의과학회 1997 Investigative Magnetic Resonance Imaging Vol.1 No.1

        목적: 기능적 MR영상을 이용하여 일차운동중추 및 부운동중추의 활성화 부위의 확인 및 편측성을 확인서을 확인하고자 하였다. 대상 및 방법: 7명의 정상성인을 대상으로 echoplanar imaging 혈액산소노도의존(blood oxygen level dependent)기법을 이용하여 운동자극에 의한 뇌피질활성화 검사를 시행하여싸. 사용한 MR기기는 1.5T Siemens Magnetom Vision system이고 표준두부코일을 사용하였다. EPI의 parameter는 TR/TE:1.0/660 msec, 숙임각: $90^{\circ}$, field of view: $22cm{\times}22cm,{\;}matrix{\;}:{\;}128{\times}128$, 절편갯수/절편두께/간격: 10/4mm/0.8mm와 지방억제기법이 추가되었다. 손가락운동을 한쪽 손의 검사에 3회의 운동자극기간과 3회의 휴식기를 번갈아 좌측손과 우측손을 따로 시행하였다. 영상처리 software는 Stimulate 5.0을 사용하였고 통게적인 방법은 cross-correlation을 이용하였다. 좌우측 반구의 활성화시의 평균신호강도의 상승률과 일차운동중추와 부운동중추부위의 활성화된 voxel의 갯수를 구하여 좌측 및 우측손의 운동시의 좌우측반구의 활성화된 voxel의 갯수를 비교하였다. 그리고 각 반구의 활성화된 voxel의 총합을 구하여 각반구의 비대칭성을 확인하는 지표로 삼았다. 결과: 부운동중추에서 우성반구의 신호 상승률은 2.49-3.06%로 일차운동중추의 4.4-7.23%보다 낮은 상승류을 보였다. 우측이나 좌측손가락운동시 부운동중추의 좌, 우측 반구의 평균신호강도의 상승률에는 유의한 차이가 없었다(p>0.01). 활성화된 voxel의 갯수에 있어서도 유의한 차이가 없었다. 반구의 비대칭성을 확인하기 위하여 각각의 뇌반구의 활성화 voxel의 총합을 구하였을때 일차운동중추의 경우는 유의성있는 차이를 보였으나(p<0.05) 부운동중추의 경우에는 차이가 없었다. 결론: 일차운동중추는 반대측 뇌반구의 우세 및 좌측반구가 우세한 비대칭성을 보였으나 부운동중추는 한쪽 반구의 비대칭성이 약한결과를 보였다. Purpose: To investigate the localization and functional lateralization of the supplementary motor area (SMA) in motor activation tests in comparison to that of the primary motor area. Materials and Methods: Seven healthy volunteers obtained echoplanar imaging blood oxygen level dependent technique. This study was carried on 1.5T Siemens Magnetom Vision system with the standard head coil. Parameters of EPI were followed as; TR/TE : 1.0/66.0msec, flip angle: $90^{\circ}$, field of view: $22cm{\times}22cm,{\;}matrix:{\;}128{\times}128$, slice number/slice thickness/gap: 1O/4mm/0.8mm with fat suppression technique. Motor task as finger opposition in each hand consisted of 3 sets of alternative rest and activation periods. Postprocessing were done on Stimulate 5.0 by using cross-correlation statistics. To compare the functional lateralization of the SMA in the right and left hand tests, each examination was evaluated for the percent change of signal intensity and the number of activated voxels both in the SMA and in the pri¬mary motor area. Hemispheric asymmetry was defined as difference of summation of the activted voxels between each hemisphere. Results: Percent change of signal intensity in the SMA (2.49 -3.06%) is lower than that of primary motor area(4.4 -7.23%). Percent change of signal intensity including activated voxels were observed almost equally in the right and left SMA. As for summation of activated voxels, primary motor area had significant difference between each hemisphere but not did the SMA. Conclusion: Preferred contralateral dominant hemisphere and hemispheric asymmetry were detected in the primary motor area but not in the SMA.

      • KCI등재

        척추경막외종괴의 방사선과학적 고찰

        이호규 대한영상의학회 1987 대한영상의학회지 Vol.23 No.3

        It is often difficult to differentiate each pathologic entity among vrious spinal epidural masses on the radiologic bases. We retrospectively analyse radiologic findings of 67 cases of pathologically probven spinal epidural mass to find out any specific findingsof each epidural mass. RESULT : 1. Of 67 cases, metastasis, epicural abscess, neurogenic tuor and meningioma are most common. The others consist of epidural angioma, vertebral hemangioma, chondrosarcoma, fibrosarcoma, eosinopilic granuloma, lymphoma, lipoma and lymphoid hyperplasia. 2. Destruction of the adjacent bone was commonly associated with the epidural mass inmetastasis and epidural abscess. It was also noted in 2 cases of chondrosarcoma, 1 fibrosarcoma and 1 eosinophilic epidural abscess. It was also noted in 2 cases of chondrosarcoma, 1 fibrosarcoma and 1 eosinophilic granuloma. 3. Pressure erosion of adjacent bone was demonstrated in neurogenic tumor and meningioma. 4. Narrowing of intervertebral space was see in only 27% of epidural abscess. 5. The paraspinal tumor was associated in 67%of metastasis, 80% of epidural abscess, 75% of neurogenic tumor, 33% of meningioma. 6. The intradural tumor was associated in 50% of neurogenic tumor and 67% of meningioma. 7. On axial CT imagem, most of the epidural mass shows eccentric location with displacing dural sac to the opposite side. 8. The disease extent more than height of one verteral body was seen in 80% of epidural abscess, 58% of neurogenic tumor, 100% of epidural angioma.

      • KCI등재

        수용성 조영제와 혈관 주사약물의 부적합성에 관한 실험적 연구

        이호규 대한영상의학회 1991 대한영상의학회지 Vol.27 No.2

        With the development of low osmolar and nonionic contrast media in clinical practice, radiologists have enjoyed increased clinical application along with other advantages such as improvement of patient comfort and safety. Recently, radiologists have introduced many intravascular pharmacologic agents to improve diagnostic quality and patient safety. Shortly after the introduction of these agents, however, it was observed that a precipitate results when a certain pharmacologic agent is mixed with a low osmolar contrast media. These observations have prompted testing of several other drugs used for incompatability with contrast media. To verify these reports and to investigate other medications not previously tested, the authors analyzed mixtures of contrast agents and medications in vitro and observed them for visible precipitates after operating the highspeed centrifuge. The results were as follows: 1.The contrast media that produced incompatibilities with some pharmacologic agents were ioxaglate, diatrizote, and iothalamate in the order of frequency. 2.The contrast media that produced no precipitate were iopromide and ioxithalamate. 3. The pharmacologic agents that produced precipitate with some contrast media were papaverine, Benadry 1, Protamine, Cimetidine, Regitin, and Gentamicin. Therefore, we recommend that caution should be taken to recognize incompatibilities and avoid them when intravascular pharmacologic agents of any kind may be incompatible.

      • KCI등재

        한일 전후 소설에 나타난 실존주의 양상 비교 연구 -太宰治(다자이 오사무)의 『인간 실격』과 장용학의 「요한 시집」의 작중 인물을 통해-

        이호규 한국일본근대학회 2015 일본근대학연구 Vol.0 No.48

        다자이 오사무(太宰治)의 완성된 마지막 소설 <인간실격>은 그의 자전적 요소가 깊게 배어 있으면서 전후 시대 상황과 맞물려 실존주의적 경향을 두드러지게 보이는 작품이다. 2차 대전과 한국 전쟁이라는 차이에도 불구하고 1950년대 한국소설에 나타난 실존주의 양상 역시 “재앙”으로서의 전쟁과 전후 사회라는 부조리한 현실 속에서 실존적 불안, 고독,저항의 문제를 드러내고 있다. 장용학의 <요한시집>은 대표적인 작품이다. <인간실격>에서 요조라는 인간은 합리적으로 설명되거나 상식적으로 파악이 되지 않는 인간이다. 그는 닫힌 사회에서 곧 “실격자”를 의미한다. 그러한 요조는 다자이 오사무의 자의식이 투영된 인물이다. 부조리한 현실 앞에 절망하고 철저히 소외되어 버리는 인간은 <요한시집>의 누혜 역시 마찬가지다. 한국 전쟁과 포로수용소라는 공간이 만들어내는 부조리하고 폭력적인 야만의 시공간은 본질적인 인간 자체의 부조리함을 드러내는 역할을 하고 있다. 집단적이고 폭력적이며 부조리한 역사의 청산, 개별자로서의 실존적 자유에 대한 추구가 바로 이 소설의 주제이다. 요조는 도깨비 그림을 그리는 화가가 되고자 하는 꿈을 꾸지만 아버지의 반대와 세상의 부조리함에 꺾여 그 꿈을 이루지 못한다. 아버지로부터 벗어나는 것,그것은 죄의식을 불러일으키는 엄청난 것이지만 그 품에 안길 수는 없는 실존적 자의식 때문에 요조는 술과 마약으로 자학하고, 자살을 통해 그 죄의식으로부터 도망치고자 했던 것이다. 누혜의 자살은 그에 비해 훨씬 적극적인 의미를 지닌다. 도망치고자 하는 것이 아니고 진정한 실존의 의미를 찾아 스스로에게 주어진 자유마저 희생시키고자 하는 의도에서 나온 것이기 때문이다. 두 작가의 작품을 통해 한일 전후 문학에 나타나는 실존주의적 경향을 일반화시킬 수는 당연히 없는 것이겠으나 한일전후 소설에 있어 두 작품은 가혹한 현실 속에서 지식인의 자기 존재에 대한 질문이라는 공통된 문제를 당대에 던졌던 중요한 텍스트라고 할 수 있을 것이다. 『No Longer Human』, the Osamu Dazai(太宰治)’s last novel, features his autobiographical perspective strongly incorporated in it and existential aspects interlinked with postwar circumstances. Despite the difference between the World War 2 and the Korean War, existential aspects reflected in Korea novels in 1950s reveal such issues as existential anxiety, loneliness and resistance under the unreasonable reality of wars and postwar societies. .Poem of John. is one of the most iconic pieces of literature in that era. A person named ‘Yojo’ in ..No Longer Human.. can neither be explained in a reasonable manner nor understood based on common sense. He was nothing but a “loser” in a closed society of the time. However, Yojo reflects Osamu Dazai’s sense of identity. When it comes to a postwar victim who suffers intense feeling of alienation and lost hope faced with harsh reality, Nuhye in .Poem of John. is no different. The visuospatial conditions of the Korean War and a POW camp that are characterized by irrationality, violence and barbarism reveal intrinsic irrationalities of humans. Overcoming the history marred by collective violence and irrationalities and a pursuit of existential freedom as individuals are the main theme of this novel. Yojo dreams of becoming a painter who paints goblins but fails to realize it due to the opposition of his father and the irrationality of reality. Escaping from his father is something overwhelming that instigates a strong sense of guilt but the existential self-consciousness forces him to torture himself with alcohol and drug and tries shake off the guilt through suicide. The suicide of Nuhye carries a lot more active meaning than that as it resulted from his voluntary intention to sacrifice freedom granted to him in an attempt not to escape but to find the true meaning of earnest existence. It is, of course, not rational to generalize existential aspects reflected in postwar literature of Korea and Japan through the literary works of these two authors but it is worth noting that these literary works revealed a common contemporary issue of questioning the self existence of intellectuals against the backdrop of the harsh reality.

      • KCI등재

        뇨붕증 환자의 뇌하수체후엽의 고신호강도의 회복 : 배아종 환자의 추적검사 보도

        이호규 대한영상의학회 1992 대한영상의학회지 Vol.28 No.3

        Diabetes insipidus(DI) of central origin is a clinical syndrome resulting from low blood levels of antidiuretic hormone secreted from the posterior lobe of the pituitary gland, which is usually caused by lesions involving the hypothalamus-neurohypophyseal axis. MR imaging can reveal absence of the posterior pituitary bright signal(PPBS) in DI. The authors reviewed four patients with intracranial germinomas who had DI due to hypothalamus involvement. All patients before radiotherapy revealed absence of PPBS on MRI. Three cases recovered from DI after radiotherapy and showed reappearance of PPBS. Another one patient who continued DI didn't show signal change of the posterior pituitary gland. We speculated that the reappearance of PPBS is related to clinical improvement of DI.

      • KCI등재

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