Carrageenin에 의하여 유발된 백서 슬관절염의 활액막세포에 관한 형태학적 검색

이혜수,심용식,강명재,김상호,Lee, Hye-Soo,Shim, Yong-Shik,Kang, Myoung-Jae,Kim, Sang-Ho 한국현미경학회 1994 Applied microscopy Vol.24 No.3

To investigate the morphology of the synovial lining cells, synovitis was induced by carrageenin injection into the rat knee joint cavities. Synovial membranes were excised at 1, 3, 5, 7 and 14 days, and histologic, electron microscopic, histochemical (periodic acid Schiff: PAS, toluidine blue), and enzyme histochemical (acid phosphatase: ACP, nonspecific esterase: NSE and endogenous peroxidase) studies were performed. The results are as follows: Carrageenin induced synovial membrane hypertrophy with synovial cell proliferation and granuloma formation. The proliferated synovial lining cells and macrophages in the granulomatous lesion had round to oval nuclei and large, plump cytoplasm with many phagocytotic materials and vacuoles. Electron microscopically, these cells had small number of granular endoplasmic reticulum and many lysosomes, phagosomes and vaculoes. Mitotic figures were observed at early stage of experiment. PAS and toluidine blue stains showed strongly positive reaction in the cytoplasm of the proliferated lining cells and macrophages in granulomatous lesion. ACP and NSE activities were strong positive in the cytoplasm of the proliferated synovial lining cells and macrophages in the granulomatous lesion. But endogenous peroxidase stains were negative in all prolifeative lining cells and macrophages in granulomatous lesion. Conclusively, carrageenin-induced synovitis showed proliferation of synovial lining cells and granuloma formation in deep layer. The macrophages, which consisted of the lesions and have active phagocytic function, were speculated to proliferate by mitosis of superficial synovial A cells and histiocytes in the deep layer of the synovial membrane.

소규모 전력 소비자 대상 수요자원 거래시장의 필요성 및 시범운영 결과 분석

이은정(Eun-jung Lee),이경은(Kyung-eun Lee),이혜수(Hye-su Lee),이효섭(Hyo-seop Lee),김은철(Eun-cheol Kim),이원종(Wonjong Rhee) 한국통신학회 2017 韓國通信學會論文誌 Vol.42 No.4

농약 기준 및 위해평가 국제화를 위한 농약 가공계수 연구

이혜수 ( He Su Lee ),서정아 ( Jeong A Seo ),김동현 ( Dong Hyun Kim ),조미현 ( Mee Hyun Cho ),김현준 ( Hyun Jun Kim ),임무혁 ( Moo-hyeog Lm ) 한국환경농학회 2020 한국환경농학회 학술대회집 Vol.2020 No.-

본 연구는 가공계수의 기초 연구 및 자료확보를 위하여 과일 등 농산물에 대한 가공계수 국제기준 설정 현황을 비교 · 분석하였으며, 10년간의 JMPR 보고서를 조사하여 가공방법 및 가공계수를 정리하여 CODEX의 농약 기준설정에 대한 근거 자료를 조사하였다. CODEX에 등록된 230종 농약 중 가공연구가 수행된 120여종 농약을 3개년(2019~2021년)으로 나눈 다음, 연차별로 대상 식품에 대한 기준 설정 및 위해평가를 위한 섭취량 분리 및 가공계수를 제안하는 요약서 작성을 수행하였다. Maleic hydrazide의 감자에 대한 가공연구는 삶음, 오븐조리, chip에 대한 연구가 제출되어 가공계수는 각각 0.52, 1.2, 0.92로 나타났으며 위해평가에 사용하였으며, fenamiphos는 토마토, 오랜지, 사과, 포도, 파인애플에 대한 가공연구가 제출되어 각 농산물별 위해평가에 사용 가능한 가공계수는 토마토 주스 0.88, 토마토 케첩 0.58, 오렌지 주스 0.28, 사과 주스 0.78, 건포도 1.22, 파인애플 주스 1.19 이였다. Parathion의 가공계수는 각각 사과 주스 0.072, 포도 주스 0.09, 건포도 0.35, 옥수수가루 0.68, 옥수수 정제유 2.4, 백미 0.46, 수수가루 0.4, 밀가루 0.35, 해바리기씨 정제유 0.42, 면실 0.014으로 나타났으며, pyrethrins는 오렌지 주스 <0.66, 건포도 <0.48, 포도 주스 <0.48, 토마토 퓨레 <0.52, 토마토 주스 <0.52로 가공계수가 산출되었다. 또한, paraquat는 감자, 옥수수, 수수, 해바라기씨에 대한 연구가 되었으며 각 농산물별 가공계수는 감자 crips >0.95, 옥수수가루 1.5, 옥수수 정제유 <0.25, 수수가루 0.14, 해바라기씨 정제유 <0.05로 나타났다. Pirimiphos-methyl의 가공계수는 밀가루 0.17, 빵 0.097이었으며, trinexapac-ethyl은 밀가루 0.43이었으며, flonicamid은 사과 주스 3.7, 복숭아 통조림 0.7, 복숭아 주스 0.8, 복숭아 잼 0.7, 토마토 페이스트 16.1, 감자 chips 0.95, 유채씨 정제유 0.1이었으며, boscalid는 오렌지 주스 <0.23, 사과 주스 0.08, 포도 주스 0.42, 와인 0.35, 건포도 2.5, 토마토 주스 0.15, 토마토 페이스트 0.73, 대두 정제유 0.42, 밀가루 0.34, 딸기 잼 0.44, 오이피클 0.52, 당근 주스 <0.12, 당근 통조림 <0.12, 옥수수 정제유 6.0, 유채씨 정제유 1.29로 가공계수가 산출되었다. 또한, 국내 가공계수 산출 대상 농산물인 쌀을 가공 중 농약 감소율을 분석하여 대 국민 홍보자료로 사용하기 위하여 쌀에 농약을 침지하여 실험을 진행하였다. 침지한 현미를 세척, 취반으로 가공하였으며 현미를 도정하여 백미를 세척, 취반, 백설기, 죽, 쌀과자, 뻥튀기로 가공 후 가공계수를 산출하였다. 백설기, 죽, 쌀과자, 뻥튀기는 가공 중 잔류량 변화를 알아보기 위하여 가공 단계별 시료를 채취하여 분석을 진행하였다. 가공계수를 산출한 결과, buprofezin은 현미를 3회 세척하였을 때 0.6, 백미는 0.5로 나타났으며, 현미밥 0.4, 백미밥 0.1, 백설기 0.01, 죽 0.01, 쌀과자 0.01로 산출되었다. Tebufenozide는 3회 세척 시 현미에서 0.4, 백미 0.3으로 나타났으며, 현미밥 0.3, 백미밥 0.1, 백설기, 죽, 쌀과자는 모두 0.01로 산출되었다. Etofenprox의 경우, 3회 세척 시 현미에서 0.4, 백미 0.3으로 나타났으며 현미 밥 0.3, 백미밥 0.1, 백설기 0.02, 죽과 쌀과자는 0.01로 가공계수가 산출되었다, Flubnediamide는 3회 세척 시 현미 0.4, 백미 0.3으로 나타났으며, 현미밥 0.2, 백미밥 0.1,백설기 0.02, 죽과 쌀과자 0.01 로 산출되었다. 따라서 4종 농약은 세척 및 가열 가공으로 인하여 농약이 분해 및 제거되는 것으로 나타났다.

스마트워크3.0을 기반으로 하는 공간구성의 이동 특성에 관한 연구

이혜수(Lee, hye-su),남경숙(Nam, Kyung-Sook) 한국실내디자인학회 2016 한국실내디자인학회 학술대회논문집 Vol.2016 No.05

Coworking space explicated working space and network communication focused, that also finding people want to collaborated. the reason for this is Smart world now. Smart Work Version 3.0 is absorbed to increase the productivity and efficiency through a case of co-working spaces are applied to In response to the rapidly changing needs of creative work space is requirements of smart world co-working space type of investigation It studies the moving feature in accordance with the space .Interior and behavioral analysis and understanding. The analysis of similarities and differences between users. This study divides the space ,personal space and meeting space, resting place of the focus co-working space in Seoul. The study represents the co-working as smart work version 3.0 community building for intersection area. Based on 3.0 smart work and co-working space environment improved concentration, variety of communication. From an this research the time check collaboration place to stay, therefore resulting answers construction of space for movement features.

『뉴 아틀란티스』와 『로빈슨 크루소』에 나타난 신대륙에 대한 상상력: 식민주의와 유토피아 사용법

이혜수 ( Hye Soo Lee ) 한국18세기영문학회 2013 18세기영문학 Vol.10 No.1

I examine in this paper how early modern utopian literature involved European colonial imagination for the New world, and how it has historically evolved into a modem utopian novel by reading Francis Bacon`s New Atlantis and Daniel Defoe`s Robinson Crusoe, The New World plays a great role in these texts, which take the South America and the Caribbean Coast as the background of each narrative. The New Atlantis presents the South America, the neighbor country of Bacon`s utopian society of Bensalem, as plato`s “great Atlantis.” Notabaly, however, even though the image of the South America in The New Atlantis is partly overlapped with a legendary continent and that it obliquely reflects European admiration for the newly discovered land the South America is to be conquered by Bensalem and eventually would degenerate into a land of :simple and savage people,” For Bacon`s utopian project embodied in Bensalem lies in building a NEW Atlantis, where formidable and merciless science rules over knowledge, religion, and politics. The purpose of Salomon`s House (an authoritative science research institute in Bensalem) to “enlarge[e]the bounds of Human Empire, to the effecting of all things possible” also shows how Bacon`s scheme for the predomination of science over humanities, like Thomas More`s Utopia is closely related to the imperial conquest of the nature and natives of the New world. while there is a mixture of attraction and contempt about the New World in The New Atlantis and in Robinson Crusoe, a transitional work from utopian literature into the novel, the New World is imagined and represented as an almost entirely naked and savage Other that functions as a sheer object of conquest and transplantation of European culture, The Caribbean desert island in which Crusoe stays for twenty eight years essentially functions as an ``individual utopia`` a space that an individual`s desire met with on rivalry, Even when anther human being comes to his ``individual utopia`` the man who is a Caribbean native and would be called Friday would exist only as an extension of Crusoe`s aggrandized self, In other words, an individual utopia becomes a ``colonial utopia`` in Defoe`s text, Robinson Crusoe manifests how utopian literature, which was initially propelled by a longing for a better community, has been twisted and displaced into an imagination focusing on an individual in the early novel.

초기 영소설과 그로테스크 리얼리즘: 『조셉 앤드류즈』를 중심으로

이혜수 ( Hye Soo Lee ) 한국18세기영문학회 2011 18세기영문학 Vol.8 No.2

This paper examines in what way what Mikhail Bakhtin calls ``grotesque realism`` constitutes a significant part of the realist aesthetics of the early English novel through a reading of Joseph Andrews. Bakhtin advances a term of ``grotesque realism`` in Rabelais and His World as a way to explain an aesthetics that is based on ``the culture of folk humor`` and also involves ``the material bodily principle,`` ``the carnivalesque,`` ``ambivalent and regenerating laugh,`` or ``the grotesque body.`` Bakhtin`s concept of grotesque realism strongly suggests how grotesque aesthetics enacts an important feature in realist aesthetics, which has been narrowly understood as the inheritor of classical aesthetics in numerous discourses on realism. Among the early English novels in which grotesque realism plays a crucial role, Joseph Andrews is noteworthy partly because of its canonical status in the history of the English novel (rather than Gulliver`s Travels or Tristram Shandy). In this essay, I examine, first, how Joseph Andrews began as a parody of Pamela, while parody works as a key word in grotesque realism, and how the famous preface of the text values and theorizes the comic or laughter, another key element in grotesque realism. Secondly, I analyze Parson Adams, a pivotal figure in Joseph Andrews, as a character strongly associated with Sancho who is an embodiment of grotesque realism in Don Quixote, while his Quixotic aspects are satirized. Thirdly, I go through how the narrator of Joseph Andrews undermines his own authority by way of, for example, comparing his book with an inn or "Resting-Place," and then invites the reader into his banquet, rendering the text as a space of carnival and hence grotesque realism.

다니엘 디포와 근대 개인주의: 『록사나』를 중심으로

이혜수 ( Hye Soo Lee ) 한국근대영미소설학회 2014 근대 영미소설 Vol.21 No.3

This essay intervenes in and complicates the discussion that a distinguishing aspect of Daniel Defoe`s novels lies in their trenchant grasp of modern individualism by reading Roxana. Defoe`s conception and representation of modern individualism in Roxana are not fully explicated by what has been considered the hallmark of his individualism, that is, economic individualism and Protestant interiority. The eponymous heroine of Roxana is, like most hero/ines of Defoe`s other novels, a survivor of adversities and deprivations through her own resources and personal capacity; she seeks to be an autonomous and independent self regardless of the external environments. Yet while Roxana`s hard-acquired autonomy, which is initially predicated on her willful determination to be apart from morality, empowers and enables her to pursue a higher ambition, it also turns out to involve some necessary anxiety, guilty feelings, or self-alienation as the story goes on. The last part of the novel, in which Roxana`s name-sake daughter Susan haunts her and tries to reveal her identity as Roxana, stands as a compelling vignette that shows the nightmarish, repetitive, and unconscious underside of the enlightenment of modern individualism. Defoe`s last novel, the last Susan scene in particular, allows us to see that Defoe`s vision of modern individualism might be much more complex, ambiguous and ambivalent than is usually conceived.

자투리 아크릴을 활용한 업사이클링 장신구 디자인 연구

이혜수(Lee, Hye Soo),박보람(Park, Bo Ram) 한국디자인문화학회 2018 한국디자인문화학회지 Vol.24 No.2

국내 업사이클링(Upcycling) 시장이 가파르게 성장하고 있다. 이에 본 연구는 지역 문화를 기반으로 하는 업사이클링 디자인에 주목하여 한국의 간판 제작에 주로 사용되는 아크릴(Acrylic)을 활용한 업사이클링 장신구 디자인 연구를 목적으로 하였다. 문헌연구 방법과 사례연구 방법으로 진행하였다. 먼저 문헌연구를 통해 재활용 패러다임(Paradigm)의 변화와 아크릴의 특성, 한국 간판 동향의 이론적 고찰을 진행하였다. 다음으로 업사이클링을 통한 장신구 디자인의 국내외 사례 9개 중 11개의 업사이클링 장신구디자인을 선정하여 업사이클링 디자인 제작 기법(이루미 등, 2015)으로 분석하였다. 사례 분석 결과 5가지의 업사이클링 디자인 기법 중 Melting and Compressing 기법은 업사이클링 장신구에 활용되지 않았다. 자투리 아크릴을 활용한 업사이클링 장신구의 경우에도 위의 기법을 제외한 나머지 4가지 기법이 적용 가능하였다. 결론적으로 자투리 아크릴의 무독성, 경량성 등의 특성으로 미루어 볼 때 자투리 아크릴은 장신구 디자인 소재로 활용이 적합하였다. 더불어 유광 아크릴의 표면은 장신구의 반짝임을 표현하였다. 본 연구에서는 다양한 업사이클링 기법을 활용한 자투리 아크릴 장신구 디자인 제안하였다. 향후 연구에서는 업사이클링 장신구 디자인의 조형적 연구와 더불어 자투리 아크릴을 활용한 다양한 업사이클링 연구을 기대한다. The domestic upcycling market is growing rapidly. In this regard, this paper aimed to study the upcycling accessory design using offcut acrylics, which is based on the unique sign culture of Korea. The research was conducted through literature research and case study. First, through literature research, theoretical considerations were done based on changes in recycling paradigm, acrylic properties, and trend of Korean sign business. Secondly, 11 upcycling accessory designs out of 9 domestic and international case studies were analyzed based on upcycling product design techniques(Lee, et al, 2015). Lastly, the upcycling accessory designs using offcut acrylics were suggested. As a result, it showed that four out of five upcycling product design techniques were used. Even with the upcycling accessory design using offcut acrylics, Melting and Compressing technique was not used, while the other four techniques were applicable. Through this research, by the non-toxic and lightweight properties of acrylic, the material was suitable to use as an accessory design. In addition, its glossy surface was able to express the glitter of accessories. In the study, a variety of techniques were used to propose the upcycling accessories using offcut acrylics. Furthermore, the study on formative design of the offcut acrylic accessories and various upcycling design studies on offcut acrylics are needed.

“내 당돌함 때문에 나를 좋아했나요?”: 『오만과 편견』의 새로움과 낯익음

이혜수 ( Hye Soo Lee ) 근대 영미소설 학회 2007 근대 영미소설 Vol.14 No.1

In this essay, I argue that Elizabeth Bennet, the witty, vivacious, and satirical heroine in Jane Austen`s Pride and Prejudice, inherits the tradition of `a strong woman` in the genre of comedy (particularly Restoration comedy) before the novel. Feminist literary historians like Jane Spencer regard Pride and Prejudice as a novel that fundamentally succeeds to `the didactic tradition of reformed heroine,` the central tradition of eighteenth-century women novelists. Yet Elizabeth stands apart from `sentimental heroines` as well as `reformed heroines,` two representative heroines in eighteenth-century novels. Rather, she looks similar to `strong heroines` in comedy, such as Rosalind in As You Like It, Hellena in The Rover, or Millament in The Way of the World, in that she is witty, independent, or subversive, and pursues her happiness. Elizabeth Bennet does not accept the norm of `an ideal woman` portrayed in the conduct books, but she resists not only arrogant male prerogative but also conceitful high-handedness of the upper class. Elizabeth`s challenge to Darcy`s male privilege and his class hauteur, as is seen in her defiance of the implication of his silence in the Netherfield party scene, however, turns out to be the starting point of Darcy`s admiration of her. Their marriage is not a reward for a reformed heroine but rather the triumph of Elizabeth`s female “liveliness” over Darcy`s pride in class and sex. What Georgiana, Darcy`s sister, learned from the marriage illustrates how their marriage is not a conservative kind but a genuinely carnivalesque one.

유도 경기규칙 개정에 따른 경기내용분석: 2016년 리우올림픽과 2020년 도쿄올림픽 비교

이혜수 ( Lee Hye Su ),강성기 ( Kang Seoung Ki ),김은희 ( Kim Eun Hee ),전기영 ( Jeon Ki Young ) 한국체육학회 2022 한국체육학회지 Vol.61 No.1

본 연구는 유도 종목의 경기규칙 개정에 따라 경기내용이 어떻게 변화하였는지 확인하기 위해 2016년 리우올림픽(429경기)과 2020년 도쿄올림픽(426경기) 대회를 비교 분석하였다. 자료처리는 빈도분석과 백분율(%), 교차분석(χ²)을 실시하였으며 통계적 유의수준은 ⍺=.05로 설정하였다. 연구결과 여자선수들의 득점유형에서는 차이가 나타났지만(p<.001), 남자선수들은 차이가 나타나지 않았다(p=.165). 기술득점경기의 점수유형에서는 남ㆍ여 모두 차이가 나타났으며(p<001. p<.001) 벌칙득점경기의 점수유형에서도 남ㆍ여 모두 차이가 나타났다(p<.001, p<.001). 남자선수(34.7%)와 여자선수(17.2%) 모두 ‘골든스코어’ 경기가 증가하였다. 본 연구의 결과를 요약하면 첫째, 남ㆍ여 선수 모두 기술득점경기는 증가하고 벌칙득점 경기는 감소하여 긍정적인 결과를 나타냈지만 남자선수들의 경우 한판승 경기가 감소하였다. 둘째, ‘지도’가 승패를 결정할 수 없는 규정으로 인해 남ㆍ여 선수 모두 골든스코어 경기가 급격히 증가했다. 셋째, 남자선수들은 경기시간이 단축됨으로 연장전 경기가 증가되고 이로 인해 ‘한판’이 감소하였다. 결론적으로 국제유도연맹이 경기규칙을 변경하므로 긍정적인 유도(Positive Judo)의 목표는 부분적으로 이루었지만 모든 목표가 달성되지는 않았다. 향후 국제유도연맹의 새로운 규칙을 도입할 때 유도 경기내용분석에 대한 연구는 현장에서 유용한 자료로 활용될 것이며 유도 경기분석에 관련된 연구를 지속적으로 모색하여 다가올 2024년 파리올림픽에 기여할 수 있기를 기대한다. This study compared and analyzed the 2016 Rio Olympics (429 games) and the 2020 Tokyo Olympics (426 games) to see how the contents of the event changed according to the revision of the judo rules. For data processing, frequency analysis, percentage (%), and cross-Vaildation (χ²) were performed, and the statistical significance level was set to ⍺=.05. As a result of the study, there was a difference in the scoring patterns of female athletes (p=.001), There was no difference in male athletes (p=.165). There was a difference in the score type of the Positive(p=001. p<.001), and there was a difference in the score type of the Negative for both males and females (p<.001, p<.001). Both male players (34.7%) and female players (17.2%) showed an increase in Golden Score matches. To summarize the results of this study, First, both male and female players increased Positive and decreased Negative, but it is difficult to interpret this as a positive result because the ippon for male players decreased. Second, due to the rule that ‘Shido’ cannot decide whether to win or lose, both men and women’s and women’s Golden Score matches have increased sharply. Third, due to the shortened game time for male players, overtime matches increased, which resulted in a decrease in ippon. In conclusion, as the International Judo Federation changed its rules of play, the goal of positive Judo was partially achieved, but not all goals were achieved. When introducing new rules by the International Judo Federation in the future, research on judo content analysis will be used as useful data in the field and is expected to contribute to the upcoming 2024 Paris Olympics by continuously seeking research related to judo analysis.