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이자영,김현경,허정원,김명신,공선영,조영욱,김인숙,이승태,이우인,이영경,장윤환,김선희 대한진단검사의학회 2016 Laboratory Medicine Online Vol.6 No.1
대한진단혈액학회에서는 혈액종양환자를 대상으로 표준화된 진단 절차에 대한 임상 진료 권장사항을 제공할 수 있는 지침을 개발하고자 하였다. 설문조사 및 National Comprehensive Cancer Network Guidelines, European LeukemiaNet recommendations을 포함한 국제 지침을 바탕으로 혈액종양 초기 진단 검사 항목 지침을 수립하였다. 본 지침은 국내 혈액종양 진단에 유용하게 활용되고 검사표준화에 기여할 것이며 새롭게 소개되는 분자진단기술이 위원회의 합의 과정을 통해 지속적으로 검사 항목 지침에 통합될 것이다. The standardization committee of the Korean Society for Laboratory Hematology sought to establish standardized testing guidelines for the diagnosis of hematologic malignancies. The guidelines were developed on the basis of survey results and international guidelines, including the National Comprehensive Cancer Network Guidelines and European LeukemiaNet recommendations. The committee expects that the diagnostic guidelines presented here will enhance diagnostic test standardization and clinical decision making and that the novel developments due to new molecular technologies will be integrated into the diagnostic algorithms through ongoing consensus initiatives.
이자영,전연숙,이순영 한국피부과학연구원 2012 대한피부미용학회지 Vol.10 No.1
The purpose of this study is to discover a way to improve the quality of high school textbooks on skin care by comparative analysis of their structure and contents against those of actual curriculum. The research is also expected to provide a foundation for subsequent development of a textbook on skin care. In order to achieve these objectives this research studied three textbooks based upon the 7th Revised Educational Curriculum. In regard to research method, the contents in each textbook were categorized into six different areas, according to the interpretation of 7th Revised Educational Curriculum. The research results have revealed that the government-designated textbook contains slightly more diversified structure and that the contents of the sampled textbooks do not correspond to those of National Educational Curriculum. Therefore, it is suggested that the skin care textbooks that are currently in use need to be reviewed at a political level such that they could be practically utilized in secondary education.
이자영,정현정,김미금,위원량 대한안과학회 2014 Korean Journal of Ophthalmology Vol.28 No.3
Purpose: This study investigated interleukin (IL)-17-secreting cell involvement in sterile inflammation, and evaluatedthe effect of mesenchymal stem cells (MSCs) on IL-17-secreting cell immunologic profiling. Methods: Twenty mice were sacrificed at time points of 6 hours, 1 day, 1 week, and 3 weeks (each group, n =5) after the cornea was chemically injured with 0.5N NaOH; IL-17 changes in the cornea were evaluated usingenzyme-linked immunosorbent assay. Further, IL-17 secreting cells were assessed in the cervical lymph nodesby a flow cytometer. Rat MSCs were applied intraperitoneally in a burn model (n = 10), IL-17-secreting T helper17 (Th17) cell and non-Th17 cell changes were checked using a flow cytometer in both cornea and cervicallymph nodes at 1week, and compared with those in the positive control (n = 10). Results: IL-17 was highest in the cornea at 1 week, while, in the cervical lymph nodes, IL-17-secreting cellsshowed early increase at 6 hours, and maintained the increase through 1 day to 1 week, and levels returnedto the basal level at 3 weeks. Specifically, the non-Th17 cells secreted IL-17 earlier than the Th17 cells. Whenthe MSCs were applied, IL-17 secretion was reduced in CD3(+)CD4(-)CD8(-), CD3(+)CD4(+)CD8(-), and CD3(+)CD4(-)CD8(+) cells of the cervical lymph nodes by 53.7%, 43.8%, and 50.8%, respectively. However, in thecornea, IL-17 secretion of CD3(+)CD4(-)CD8(-) cells was completely blocked. Conclusions: The results indicated that both IL-17-secreting non-Th17 and Th17 cells were involved in the chemicalburn model, and MSCs appeared to mainly modulate non-Th17 cells and also partially suppress the Th17 cells.