외부법의 종양치료활용에 대한 고찰

이용연,송기철,최병렬,서상훈,최우진,조정효,이연월,손창규,조종관,유화승,Lee, Yong-Yeon,Song, Kee-Cheol,Choi, Byung-Lyul,Seo, Sang-Hoon,Choi, Woo-Jin,Cho, Jung-Hyo,Lee, Yeon-Weol,Son, Chang-Gue,Cho, Chong-Kwan,Yoo, Hwa-Seung 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.4

Objectives: The purpose of this study was to explore some new therapies to control clinical symptoms of patients with terminal cancer by using external applications. Methods: We investigated some literatures on the external applications for cancer patients and made diagrams. Results: The results are summarized as follows. External applications are one of the traditional oriental medical methods and these are effective for pain control, ascites & pleural effusion and palpitable mass. It has some characteristics which are simple, safe and popular, but we must pay attention carefully to allergic reaction and toxicity in using external applications. The therapeutic portion of external applications are decided by discipline of syndrome and disease differentiation, and the prescriptions are composed of antitumor herb medicines. Conclusions: From the above results, it is expected that external applications are useful to improve clinical symptoms and quality of life(QOL) for patients with terminal cancer who cannot intake foods or medicines.

호스피스 케어를 위해 입원한 말기 암 환자의 사망직전 의료비용 실태 조사

유상연,이혜리,이용제,안미홍,염창환,Yoo, Sang-Yeon,Lee, Hye-Ree,Lee, Yong-Je,Ahn, Mi-Hong,Yeom, Chang-Hwan 한국호스피스완화의료학회 2002 한국호스피스.완화의료학회지 Vol.5 No.2

배경 : 세계적으로 암의 발생률과 사망률은 증가하는 추세로, 그로 인한 의료비 상승의 문제로 국가 정책의 필요성이 대두되고 있다. 이에 저자 등은 호스피스 케어를 위해 입원한 말기 암 환자들의 의료비용 실태를 조사하고 이와 관련된 요인도 함께 살펴보아 불필요한 의료비용 부분의 효과적 감소에 도움이 되고자 하였다. 방법 : 2000년 7월 1일부터 2002년 6월 30일 사이에 경기도 고양시에 소재한 모 병원 가정의학과에 말기 암으로 입원하여 사망한 환자 259명을 대상으로 인구통계학적 자료 암의 기왕력, 임상소견, 의료비용을 조사하였다. 의료비용은 환자의 사망직전 입원 당시의 원무과 계산서를 근거로 세부 항목을 조사하였다. 인구통계학적 특성, 암의 기왕력, 임상 소견과 평균 의료비용과의 상관관계를 ANOVA로 조사하였다. 결과 : 말기 암 환자 259명중 남자가 135명(52.1%), 여자가 124명(47.9%)이었으며, 암의 종류는 위암이(58명, 22.4%) 제일 많았다. 입원 당시의 임상소견은 식욕부진이 227명(87.6%), 통증이 199명(76.8%), 오심 구토가 152명(58.7%) 순으로 높게 나타났다. 총 의료비용은 740,628,045원이었으며 환자 1인당 평균 의료비용은 $285,968{\pm}3,070,272$원이었다. 총 의료비용 중에서 주사료가 237,038,259원(32.0%)로 가장 많았고 병실료가 206,416,669원(27.9%), 검사료(임상병리 검사료와 진단 방사선료)가 103,417,747원(14.0%) 순이었다. 평균 의료비용은 주사료, 치료방사선료, 병실료 순으로 높았다. 인구통계학적 특성, 암의 기왕력, 임상소견의 항목 중 통증만 유일하게 평균 의료비용과 상관관계가 있었다(P<0.05). 결론 : 호스피스 케어를 받는 말기 암 입원 환자들에서 불필요한 마약성 진통제 등 주사 투여를 가능하면 줄이고 가정 내 호스피스를 활성화하고 과도한 검사를 줄임으로써 보다 더 효과적인 비용 절감을 도모할 수 있을 것으로 보인다. Purpose : Death due to cancer has been continuously increasing, therefore cancer is the first in the cause of death now. A national policy for the elevation of medical costs in cancer patients is necessary, therefore, we searched for the medical costs and its related factors in terminal cancer patients for the effective reduction of the medical costs. Methods : We reviewed the medical records of 259 hospitalized terminal cancer patients who had died during the period of July 1, 2000 to June 30, 2002. History of cancer included type of cancer, type of past treatment, existence of metastasis. Clinical manifestation was examined and medical costs on last admission was categorized based on the account of charges of the department of patient affair on the last hospitalization. For analysis of factors related with medical costs, ANOVA was used. Results : Of the 259 patients, the number of male was 135 cases (52.1%), and the female, 124 cases (47.9%). The most frequent type of cancer was stomach (21.9%) cancer. Of the clinical manifestation, anorexia (87.6%) was the most frequent manifestation. Total medical costs was 740,628,045won, the mean costs was $285,968{\pm}3,070,272won$. The frequent category of medical costs was injection (32.0%), medical accommodation (27.9%), examination (14.0%), in order. The only factor related with mean medical costs was pain (P<0.05). Conclusion : If unnecessary injection of opioid analgesics is reduced, hospice care at home is activated and excessive examination is reduced In terminal cancer inpatients, it will be possible to reduce the medical costs in terminal cancer patients more effectively.

마일즈 훈련효과 분석에 관한 연구

이용연(Yong-Yeon Lee),이호준(Ho Jun Lee),김용필(Yong-Pil Kim) 한국산학기술학회 2021 한국산학기술학회논문지 Vol.22 No.4

군은 군사훈련을 실전적으로 수행하기 위하여 최신 과학기술을 적용한 마일즈 장비를 활용한 훈련체계를 구축하고 있다. 마일즈 훈련체계는 마일즈 장비를 활용하여 야전에서 실기동 훈련을 실시함으로써 전투 인원과 장비의 피해상황을 실제 전장과 동일하게 모사할 수 있도록 하는 체계이다. 이를 통해 훈련병력은 실전과 유사한 체험을 할 수 있으며 특히, 정보, 통신 및 컴퓨터 시뮬레이션 등의 첨단 과학기술을 활용하는 통합체계로 구축되어 훈련에 참가하는 용사들의 훈련효과를 극대화 할 수 있다. 본 연구는 육군에서 활용 중인 마일즈 훈련효과를 과학적 기법을 활용하여 분석하였으며 중대급 마일즈를 대상으로 하였다. 특히 훈련효과를 분석하기 위한 효과지표는 관련 문헌조사 및 전문가 의견수렴을 통해 도출하였으며 Swing기법을 적용하여 효과지표별 가중치를 산출하고 훈련 경험자를 대상으로 한 설문조사 결과를 결합하여 최종 훈련효과를 도출하였다. 연구결과 마일즈 훈련효과는 기존의 마일즈를 활용하지 않는 훈련에 비해 2.6배 효과적이며 분산분석을 통해 신분별로 마일즈 훈련에 대한 만족도는 높으며 그 차이는 통계적으로 유의미한 것으로 도출되었다. The Army is constructing a training system using Miles equipment that applies the latest science and technology to carry out military training. The Miles training system is a system that uses Miles equipment to simulate the damage situation of combat personnel and equipment in the same way as an actual battlefield by conducting practiced maneuvers in the field. Through this, the training force can experience conditions similar to an actual battle. In particular, the training effects of the warriors participating in the training can be maximized by establishing an integrated system that utilizes cutting-edge science technologies, such as information communication and computer simulation. This study analyzed the effects of Miles training in the army using scientific techniques targeted at the mid-range Miles. In particular, the effect index for analyzing the training effect was derived from a literature survey and expert opinions. The weight of each effect index was calculated by applying the Swing method. The final training effect was calculated by combining the results of the survey from train-experienced people. The Miles training effect was 2.6 times more effective than previous training without using Miles, and the satisfaction rate with Miles training according to status was high through variance analysis, and the difference was statistically significant.

산후조리원에 입원한 산모의 사상체질과 1회 유축한 모유량과의 상관성에 관한 연구

이용현 ( Yong Hyun Lee ),송호림 ( Ho Lim Song ),배경연 ( Kyeong Yeon Bae ),정재중 ( Jae Joong Jung ),유상민 ( Sang Min Yoo ),황진우 ( Jin Woo Hwang ),최인호 ( In Ho Choi ),육상숙 ( Sang Suk Yuk ),임은미 ( Eun Mee Lim ) 대한한방부인과학회 2006 大韓韓方婦人科學會誌 Vol.19 No.2

항암약침의 최신경향에 대한 고찰

이용연,조정효,이연월,손창규,조종관,황규정,유화승,Lee, Yong-Yeon,Cho, Jung-Hyo,Lee, Yeon-Weol,Son, Chang-Gue,Cho, Chong-Kwan,Hwang, Kyu-Jeong,Yoo, Hwa-Seung 대한약침학회 2001 Journal of pharmacopuncture Vol.4 No.3

Objective: The purpose of this study is to develop and activate anti-tumor herbal acupuncture for cancer patients in South Korea. Methods: We investigated some literatures on anti-tumor herbal acupuncture which is used in South Korea and China, and made diagrams. Results: The results are summarized as follows. Anti-tumor herbal acupuncture is one of the traditional oriental medical method which is effective for cancer patients. In domestic studies, most of herb materials are belong to action of cooling&detoxification(25.0%) and strengthening body resistance(46.4%) which are proved to have effects of anti-tumor, immune activation and preventing tumor. In China, point injection therapy are used for improving symptoms of cancer patients and hea1ing tumor. Also herbal intravenous injection is used for combination of chinese traditional and western cancer therapy and treating cancer patients variously. Conclusions: From the above results. it is expected that anti-tumor herbal acupuncture is useful to improve clinical symptoms and quality of life(QOL) of cancer patients. Also we must develop new progressive methods of point injection and herbal intravenous injection for treating cancer patients, and advance clinical studies and trials.

항암단(抗癌丹)을 투여(投與)한 대장암(大腸癌) 환자(患者) 83례(例)에 대한 임상보고(臨床報告)

이용연,서상훈,유화승,최우진,조정효,이연월,손창규,조종관,Lee, Yong-Yeon,Seo, Sang-Hoon,Yoo, Hwa-Seung,Choi, Woo-Jin,Cho, Jung-Hyo,Lee, Yeon-Weol,Son, Chang-Kyu,Cho, Chong-Kwan 대한암한의학회 2000 大韓癌韓醫學會誌 Vol.6 No.1

Clinical studies were carried out 83 cases of patients with colorectal cancer treated by Hangamdan(抗癌丹) from January 1th 1998 to September 30th 2000. The results were summarized as follows; 1. Distribution of those attached by colorectal cancer, by sex, showed that Male is more then Female, by age, showed that the number of fifties is majority. 2. Distribution of diagnostic stage, in descending order; stage III(53%, top), stage IV(45.8%). 3. The effects of maintenance and improvement in the symptoms with traditional oriental therapy(83.3%) and combined treatment of western and oriental therapy(92.1%) were observed. The effects of the symptoms were as follows: diarrhea(37.3%), abdominal pain (25.3%), general body weakness(22.9%), nausea(20.5%) and etc. in orders. 4. Analysis of hematology attached by colorectal cancer, maintenance and increasing of WBC(89.9%), RBC(74.7%), Hgb(81.1%), Platelet(92.4%) were observed. After taken Hangamdan, the safety of the liver and kidney were as follows; maintenance and decreasing of AST(85.9%), ALT(94.8%), GTP(87.5%), Creatinine(90.9%) were observed. 5. of IL-12 and $IFN-\gammer$ attached by colorectal cancer, increasing of IL-12(53.3%), IFN-{\gammer}(80%)$) were observed. 6. Analysis of QOL attached by colorectal cancer, maintenance and improvement of combined treatment of western and oriental therapy(89.6%), traditional oriental therapy(83.3%) were observed. 7. Analysis of survival in patients with IV stage of colorectal cancer, above 7 months(18.4%), 12 months(65.8%). 8. Analysis of antitumor effects, maintenance of traditional oriental therapy(83.3%) and maintenance and improvement of combined treatment of western and oriental therapy(80.5%) were observed. Analysis of tumor marker attached by colorectal cancer, maintenance and decreasing of CEA(78.8%) were observed. 9. Analysis of curative valuation, maintenance and improvement of traditional oriental therapy(83.3%), combined treatment of western and oriental therapy(72.7%) were observed. From the above results, it is suggested that Hangamdan has significant effects of antitumor and immune activity, also could be usefully applied for colorectal cancer patients by combination with western therapy or alone.

각종 암환자 69례에 대한 항암단의 항전이 및 재발억제효과

이용연,송기철,최병렬,서상훈,조정효,이연월,손창규,조종관,유화승,Lee, Yong-Yeon,Song, Kee-Cheol,Choi, Byung-Lyul,Seo, Sang-Hoon,Cho, Jung-Hyo,Lee, Yeon-Weol,Son, Chang-Gue,Cho, Chong-Kwan,Yoo, Hwa-Seung 대한한방내과학회 2002 大韓韓方內科學會誌 Vol.23 No.2

Purpose : Among numerous biological symptoms of cancer, matrix metalloproteinases (MMPs) are essential for tumor invasion and metastasis. HAD is used as an inhibitor of MMP gene. This study was designed to evaluate the effects of HAD on anti metastasis and preventing recurrence in cancer patients. Materials and Methods : We retrospectively analyzed the medical records of 69 cancer patients who had been administered with HAD for over 12 months continuously in East-West Cancer Center of Oriental Hospital of Daejeon University, from January 1993 to May 2002. Results : We analyzed gender, portion, stage and anti-metastasis & recurrence rates of cancer patients. Analysis of sex cases showed that the percentage of male is 62.3%, female is 37.7%. Analysis of cancer portion showed that the percentage of stomach is 31.9%, colorectum is 26.1%, lung is 21.7%, liver is 8.7%, breast is 8.7% Analysis of stage showed that the rate of III is 78.3%, IV is 13.0% and II is 8.7%. Analysis of anti-metastasis and recurrence rates showed that colorectal cancer is 77.8%, stomach cancer is 63.6%, lung cancer is 33.4% and breast cancer is 33.3% (mean : 53.6%). Conclusions : HAD has significant effects on anti-metastasis and preventing recurrence of tumor on cancer patients. So it helps to prolong the survival rates of cancer patients.

열전도성 첨가제 종류에 따른 사출 성형품의 기계적 특성에 관한 연구

이용연(Yong-Yeon Lee),김종순(Jong-Sun Kim),이동욱(Tong-Uk Lee),강태호(Tea-Ho Kang),김인관(In-Kwan Kim),김영수(Young-Soo Kim) 한국기계가공학회 2006 한국기계가공학회 춘추계학술대회 논문집 Vol.2006 No.-

In this study due to the increase of the thermal conductivity of plastics which is commonly insulator, plastics can be applied to heat-sink applications. These days quality of mechanical property and thermal conductivity of engineering plastic are required. this study focuses on evaluating for tensile properties and thermal conductivities of the test specimens. A variety of resins to which were added metal based fillers not ceramic based ones was injection-molded into test specimens. then he results of the thermal conductivity experiments were compared with the effects of each filler.

플라스틱 판형 열교환기의 성능에 영향을 미치는 인자에 관한 연구

유성연(Seong-Yeon Yoo),이용문(Yong-Moon Lee),정민호(Min-Ho Chung),정상진(Sang-Jin Jung) 대한설비공학회 2002 대한설비공학회 학술발표대회논문집 Vol.2002 No.-

공기조화 배기열 회수용 전열 열교환기의 성능에 관한 연구

유성연(Seong-Yeon Yoo),정민호(Min-Ho Chung),이용문(Yong-Moon Lee) 대한설비공학회 2002 대한설비공학회 학술발표대회논문집 Vol.2002 No.-