산불 피해 수목의 함수율 분포 특성

이연홍, 김병로 忠北大學校 農業科學硏究所 2014 農業科學硏究 Vol.30 No.2

Two Ginkgo biloba trees and one Prunus armeniaca tree was investigated between more damaged section and less damaged section by forest fire with moisture content distribution from bark to pith. One survived tree had low moisture content in sapwood, but one dead tree had high moisture content in sapwood, which meant moisture content in sapwood was not critical factor for survival in wild fire damage. So, survival in forest fire damage is come from other than sapwood moisture content, and should be further investigated

전시발표 : B 분야: 목재물리, 목재건조 ; P-08 : 산불 피해 수목의 함수율 분포 특성

김병로,이연홍 韓國木材工學會 2015 한국목재공학회 학술발표논문집 Vol.2015 No.-

암 환자에서의 임상시험용 의약품 처방 오류 분석

문진영,이연홍,이미형,김영주,곽혜선 한국병원약사회 2019 병원약사회지 Vol.36 No.3

Objective : Investigational drugs are often considered to be high-risk or hazardous medications. It is necessary to study medication errors in clinical trials. This study aimed at identifying the frequency and types of prescribing errors in oncology clinical trials. Methods : We retrospectively analyzed investigational drug orders and pharmacist intervention records from December 2015 to February 2017 in the National Cancer Center. Results : Among 12,387 investigational drug orders, 673 (5.43%) prescribing errors were detected by pharmacists. Regarding the route of administration, the prescription error rate related to IV medications was higher than that of oral medications (7.23% vs. 4.34%). The most common prescribing error in IV medications were wrong medication kit number (164 cases, 48.52 %) followed by incorrect diluent (75 cases, 22.19%), wrong dose (70 cases, 20.71%), and omission of information (20 cases, 5.92%). Meanwhile, the most common prescribing error in oral medications were wrong medication kit number (119 cases, 35.52 %) followed by incorrect quantity (67 cases, 20.0%), wrong dose (58 cases, 17.31%), and incorrect treatment duration (45 cases, 13.43%). Conclusions : This study provides the frequency and types of prescribing errors in oncology clinical trials. The pharmacist intervention may improve safety of investigational drug use.

한국인에 있어서 알렌드로네이트 제제의 제형간 유효성 및 순응도 비교

윤지원,이병구,이연홍,곽혜선,송영천,김재연,신혜영 한국임상약학회 2008 한국임상약학회지 Vol.18 No.2

Alendronate is a bisphosphonate that selectively inhibits osteoclast-mediated bone resorption. Dosing convenience is animportant element for the enhancement of patient compliance and the effective management of osteoporosis. The pur-pose of this study was to compare the effectiveness and compliance among alendronate pharmaceutical products(oralonce-weekly alendronate 70mg, daily alendronate 10mg, and once-weekly alendronate 70mg with Vitamin D3 2800IU) in terms of the change in bone mineral density (BMD), biochemical markers, and compliance estimates. A retro-spective chart review was conducted in patients with osteoporosis who received alendronate 70mg (Group 1), alendr-onate 10 mg (Group 2), or alendronate 70mg with Vitamin D3 2800 IU (Group 3) at the endocrinology department ofa hospital in Korea from Jan. 1, 1998 to Mar. 31, 2008. The primary endpoints were the increases in spine antero-pos-terior BMD T-score and femur trochanter BMD T-score, and the compliance of alendronate products. Secondary end-points included changes in bone turnover-related biochemical markers including bone-specific alkaline phosphatase,urinary N-terminal telopeptides (NTX) and osteocalcin, and in serum vitamin D3 concentration. There was no statisticaldifference in the BMD increase among the three alendronate products; spine BMD T-score increased by 0.49±0.52,0.39±0.48 and 0.50±0.41, and femur trochanter BMD T-score by 0.29±0.42, 0.21±0.53 and 0.24±0.22 in Group 1, 2 and3, respectively. With respect to the increases in femur trochanter BMD T-score and the decreases in NTX and osteocal-cin, 70mg once-weekly group was remarkably superior to 10mg daily group (p<0.05) The compliance of 70mgonce-weekly group was significantly higher than that of 10mg daily treatment group (p<0.001). In conclusion, allthree alendronate treatment groups were equivalent in effectiveness, and the compliance of 70 mg once-weekly groupwas better than that of 10 mg daily treatment group.

국내병원의 항암주사제 조제환경 및 약사 업무 현황 조사

강민경,박향민,이연주,김다진,이윤선,여미진,이연홍,문진영,허영설,김재연 한국병원약사회 2015 병원약사회지 Vol.32 No.2

Purpose : The American Society of Health-System Pharmacists has provided guidelines on handling hazardous drugs and updated its new and continuing concerns for health care workers. However, there are no such guidelines or regulations in Korea. This study aims to evaluate the work environment and the safety of healthcare workers during the preparation of antineoplastic agents in Korean hospitals. Methods : We invited a total of 110 hospitals with more than 500 beds to participate in our survey. Twenty nine hospitals participated. The self-completion questionnaire covered work place issues, the number of antineoplastic agent preparations, equipment and environmental quality control, and training about the handling of hazardous drugs. Results : There are three hospitals where the daily compounding number reached more than 600 and the average number per person was 36.5. The preparation room for hazardous drugs at nine hospitals remained positive or equal pressure. In addition, nine hospitals used a clean bench, which is not biologic safety cabinet. None of the 29 hospitals conducted an environmental sampling test to detect hazardous drugs and most of the hospitals performed an efficiency test of the biologic safety cabinet. All of the hospitals conducted personnel training and education about the safe handling of antineoplastic drugs but the length of the training period varied. In addition, none of the hospitals evaluate the health status of workers. Personal protective equipment included gowns, gloves, masks, hair caps and arm covers but not a respirator. The type of equipment and usage times varied. Most of hospitals complied with continuing preparation-compounding times of less than 2.5 hours. Conclusion : This was the baseline study to evaluate the work place and worker safety for the preparation of antineoplastic drugs. The result of our study demonstrates that it is necessary to establish standardized guidelines and improve working conditions for the handling of hazardous drugs in Korean hospitals.

실험계획법을 이용한 GDI연료펌프의 맥동저감을 위한 댐퍼 최적설계

김주영(Juyeong Kim),노진이(Jinyee Noh),이종욱(Jongwook Lee),김경남(Kyungnam Kim),박형종(Hyoungjong Park),황재근(Jaekeun Hwang),이연홍(Yeonhong Lee),윤길호(Gilho Yoon) 한국자동차공학회 2011 한국자동차공학회 학술대회 및 전시회 Vol.2011 No.11

This study optimizes the profile of the diaphragm of a pressure pulsation damper structure in a high-pressure GDI engine system which is now under development by applying the design of experiment (DOE). As a high pressure pulsation ranging from 0 to 10 Bar deteriorates the performance of GDI engine, it is necessary to attenuate the large amplitude of fluid pulsation pressure of Gasoline fuel directly injected into GDI engine. In the development of this pressure damper, it becomes an issue to design optimal profiles of the enveloping diaphragms in terms of pulsation efficiency and mechanical stress for the sake of safety. Thus, this research develops a new finite element procedure considering the internal pressure variation by assuming the isoenthalpy state of the enveloped Helium gas inside the damper and integrates the iterative finite element procedure with the design of experiment (DOE).