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이승현,이창현,김홍준,김영식,신민지,김지현,마상용,이세연,권진,오찬호,Lee, Seung-Hyeon,Lee, Chang-Hyun,Kim, Hong-Jun,Kim, Young-Sik,Shin, Min-Ji,Kim, Ji-Hyun,Ma, Sang-Yong,Lee, Se-Youn,Kwon, Jin,Oh, Chan-Ho 대한한의학방제학회 2021 大韓韓醫學方劑學會誌 Vol.29 No.2
Objectives : This study was conducted to evaluate the efficacy of a complex mixture of natural substances of ginseng and baeknyeoncho on the arthritic rats. Methods : In vitro experiments were conducted to ensure the stability of the complex. After setting toxicity and concentration by MTT assay, the antioxidant effect was measured through DPPH and ABTS radical scavenging activity. To confirm the anti-inflammatory effects of the complex, levels of nitric oxide (NO) and pro-inflammatory cytokines (IL-1β, TNF-α) were measured in LPS-treated macrophage cell lines (RAW264.7). We injected monosodium iodoacetate (MIA) 50 μl (60 mg/ml) into knee joints of rats to induce osteoarthritis. The rats were divided into three groups (normal (n=5), control (n=5), and OR (n=5) group). The control group consumed 2 mg/kg of physiological saline once a day for 4 weeks, and the OR group was mixed at a concentration of 416.5 mg/kg of Baengnyeoncho (O) and 208.25 mg/kg of red ginseng (R) and ingested 1 mL each 5 days a week. Results : This complex increased the DPPH and ABTS radical scavenging rate. The complex decreased NO production and pro-inflammatory cytokine production of macrophages. In the OR group, the secretion of cytokine in serum was decreased. In histopathological examination, the joint tissue of the composite showed less damage to the synovial membrane, cartilage, and fibrous tissue than the control group. Conclusions : As a result of this study, natural complexes have antioxidant, anti-inflammatory and cartilage protection effects. Therefore, we expect the complex to be effective in treating osteoarthritis.
이승현,김영오,Lee, Seung-Hyeon,Kim, Young-Oh 한국수자원학회 2002 한국수자원학회논문집 Vol.35 No.6
홍수기 동안의 저수지 운영은 효율적인 홍수조절과 갈수기를 대비한 용수량 확보를 모두 고려해야만 한다. 본 연구에서는 이러한 목적을 위하여 세트 컨트롤 알고리즘(SCA)을 홍수기 저수지 운영방안으로 적용하였다. SCA의 개념은 유입량이 일정한 범위 안에서 주어질 경우에 저수지의 상태가 허용범위 내에서 유지되도록 하는 저수량과 방류량의 조절 세트(Control Set)를 저수지 운영자에게 제공해주는 것이다. 본 연구에서 사용된 유입량 세트는과거자료를 이용하는 경우와 합성된 자료를 이용하는 경우, 그리고 앙상블 예측(ESP) 시나리오를 이용하는 경우로 구분하였다. SCA의 우수성을 검증하기 위하여 기존의 현행제한수위와 가변제한수위를 이용한 방안과 비교하였다. 이를 충주댐에 적용하여 총 5년(1996~2000) 동안의 모의운영을 실시한 결과, SCA를 이용하는 운영방안이 현행제한수위나 가변제한수위를 이용하는 운영방안보다 우수하였고 SCA 중에서는 앙상블 예측기법(ESP)을 이용한 경우가 가장 우수하였다. Reservoir operations during the flood season should consider both the flood control and water supply objectives. This study proposed Set Control Algorithm (SCA) as a reservoir operation method, which guarantees both objectives. The concept behind SCA is to provide operators with a set of actions that guarantee feasibility, given a set of operational constraints, and to let them select decisions within a set that satisfies other considerations. The inflow sets used in this study included; observed data, synthetic data, and ESP(Ensemble Streamflow Prediction) scenarios. Applied to the Chungju Dam operations, SCA was compared to the variable flood restricted elevation, as well as the current flood restricted elevation. A 5-year simulation analysis showed that SCA performed better than the other operation methods, and that SCA coupled with ESP performed best among the SCA cases.
체적 홀로그래픽 메모리를 이용한 스테레오스코픽 동영상 디스플레이 시스템
이승현,선광철,김은수,Lee, Seung-Hyeon,Seon, Gwang-Cheol,Kim, Eun-Su 대한전자공학회 2000 電子工學會論文誌-SD (Semiconductor and devices) Vol.37 No.2
본 논문에서는 체적흘로그래픽 메모리를 이용한 스테레오스코픽 동영상 디스플레이 시스템을 제안하였다. 각다중화된 스테레오스코픽 영상 페어의 다중 홀로그램들이 방대한 저장 능력과 실시간 랜덤 엑세스의 장점을 갖는 동일한 광굴절 매질에 기록되었다. 브래그 조건을 만족하는 입사파는 기록된 회절 격자에 의해 산란되어 스테레오스코픽 영상 페어의 방향을 따라 회절된다. 디스플레이 평면으로 회절되어 투사된 연속적인 좌안과 우안 영상으로부터 입체 비디오 영상을 관찰할 수 있다. We present a sequential stereoscopic display system using volume holographic storage. Multiple angular multiplexed stereoscopic image pairs are recorded into a photorefractive crystal that can store data with high density, transfer them with high speed, and select a randomly chosen data element. The reference beam with Bragg selectivity is scattered by the index grating and the diffracted beams are propagating along the directions of the stereoscopic image pairs. The images are to be suitably projected on the left and right display plane sequentially for stereoscopic video viewing.
LOC적용을 위한 마이크로믹서에 대한 시뮬레이션 및 해석
이승현(Seung-Hyeon Lee),강호진(Ho-jin Kang),최범규(Bum-kyoo Choi) 대한기계학회 2006 대한기계학회 춘추학술대회 Vol.2006 No.11
This paper presents the simulation result of novel micro mixer. Existing micro mixer is classified by mixing principle as active mixing and passive mixing. Both mixing principle has problems. For solving these problems, this research developed novel micro mixers based on a totally different principle compared with former principles. The mixer not only have a simple structure compared with former ones but also are able to achieve high mixing efficiency in spite of low power consumption due to using Lorentz Force. In addition, it is designed to increase the efficiency of mixing by changing the rotating direction of fluid with a polar switching circuit. Driving forces of the mixer are Lorentz force and a moving force of fluid due to electrophoresis. Because the efficiency of mixer is affected by electrode shape, it made several model. To estimate a efficiency of each mixer, it took simulation. In simulation, mixing flow of best efficiency mixer seem barrier embedded chaotic flow.
이승현 ( Seung Hyeon Lee ),손동우 ( Dong Woo Son ),심소연 ( So Yeon Shim ),서일혜 ( Yiel Hea Seo ),김석영 ( Suk Young Kim ) 대한주산의학회 2008 Perinatology Vol.19 No.4
Neonatal listeriosis is not uncommon in Western developed countries, and has significant mortality and morbidity. However, its incidence in Asian countries is relatively low and it has rarely been reported in Korea. Once infected, Listeria monocytogenes (L. monocytogenes) can have high mortality and listeriosis in pregnancy may present serious hazards to the fetus and the newborn as sepsis and death through direct infection of the placenta and chorioamnionitis. Because early detection of L. monocytogenes infection is difficult, only high index of suspicion toward this disease can hopefully prompt treatment of this life-threatening perinatal infection. We experienced a case of L. monocytogenes yielded in cultures of blood and amniotic fluid of the newborn and the mother who delivered at 25+1 weeks of gestation because of preterm labor that developed without any specific evidence of infection. We report this case with a brief review of the literature.