http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
노인(老人)의 한냉환경(寒冷環境)에서의 체온조절상(體溫調節相)에 관(關)한 실험적연구(實驗的硏究) - 특(特)히 물리적조절상(物理的調節相)에 관(關)하여 -
이대연,Lee, Dae-Yon 대한생리학회 1967 대한생리학회지 Vol.1 No.2
It has been suggested by Krag and Kountz (1950), Horvath et al. (1955) and Spurr et al. (1955) that the mechanism for prevention of heat loss is less efficient in the aged than in the young. In addition, they observed that peripheral vasoconstriction occurred more rapidly and more intensively in the aged people in response to the cold stimulus. Although it is not clear on the basis of these reports whether the Physical insulation of the aged people in cold would be different from the younger, it is evident that the vascular reactivity in response to cold seems to be altered in the aged people. Hence this investigation was undertaken to investigate the physical insulation of the aged people in a systemic manner by water immersion method which has been successfully applied to the Eskimos and Korean diving women by Rennie et al.
이대연,이영우,김완수,심선형,권필승,이인희,Lee, Dae-Yeon,Yi, Young-Woo,Kim, Wan-Su,Sim, Sun-Hyung,Kwon, Pil-Seung,Lee, In-Hee 대한임상검사과학회 2019 대한임상검사과학회지(KJCLS) Vol.51 No.2
Hwangryunhaedok-tang (HT) is prescribed in oriental medicine to treat inflammation-related diseases. This study examined the anti-bacterial effect to select the index components of Traditional Chinese Medicine (TCM) HT. The disc diffusion method and minimum inhibition concentrations (MIC) tests were conducted to measure the antibacterial activity of HT. The strains were Staphylococcus aureus ATCC 25923 and Escherichia coli 23724. Berberine and geniposide were selected as the index components of HT and were analyzed quantitatively by high-performance liquid chromatography (HPLC). As a result, the inhibition ring was formed at $11.7{\pm}1.3mm$ and $8.7{\pm}0.7mm$ at HT 20 mg and 10 mg on S.aureus ATCC 25923, respectively; and $8.0{\pm}0.0mm$ at HT 20 mg on E.coli ATCC 23724. The MIC were 31.25 mg/mL in S.aureus ATCC 25923 and 125.0 mg/mL in E.coli ATCC 23724. In quantitative analysis for standardization, HT contained 16.55 mg/g of berberine and 81.85 mg/g of geniposide. Overall, when antibiotics are developed using natural products, they may reduce the side effects and inhibit resistant bacteria. If research on HT continuously proceeds, positive developments are expected to be made in oriental medicine as well as in various other industries. 황련해독탕은 한방산업에서 염증관련 질환에 다빈도로 사용되는 처방이다. 본 연구의 목적은 전통적 한약인 황련해독탕의 항균활성을 확인하고 지표성분을 선정하는 것이다. 황련해독탕의 항균활성을 측정하기 위하여 디스크 확산법과 최소억제농도법을 사용하였다. 사용균주는 Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 23724였으며 대조군으로 oxacillin과 ciprofloxacin을 이용하여 황련해독탕의 항균활성을 확인하였다. 결과적으로 디스크 확산법에서는 S.aureus ATCC 25923에서 황련해독탕 20 mg과 10 mg은 $11.7{\pm}1.3mm$, $8.7{\pm}0.7mm$의 억제환을 형성하였으며 E.coli ATCC 23724에서는 황련해독탕 20 mg이 $8.0{\pm}0.0mm$의 억제환을 형성하였다. 최소억제농도는 S.aureus ATCC 25923가 31.25 mg/mL, E.coli ATCC 23724 에서는 125.0 mg/mL였다. 표준화를 위한 HPLC 정량분석 결과, 황련해독탕은 berberine을 16.55 mg/g 함유하고 있었으며 geniposide를 81.85 mg/g 함유하고 있었다. 천연물을 이용하여 항생제를 개발할 경우에는 내성세균을 억제하고 부작용을 줄일 수 있다는 장점이 있다. 이러한 점을 착안하여 지속적으로 연구를 진행한다면 한방산업과 더불어 여러 산업에서의 발전을 기대할 수 있을 것이다.
Kink-effect 개선을 위한 세 개의 분리된 N+ 구조를 지닌 대칭형 듀얼 게이트 단결정 TFT 구조에 대한 연구
이대연,황상준,박상원,성만영,Lee, Dae-Yeon,Hwang, Sang-Jun,Park, Sang-Won,Sung, Man-Young 한국전기전자재료학회 2005 전기전자재료학회논문지 Vol.18 No.5
In this paper, we have simulated a Symmetric Dual-gate Single-Si TFT which has three split floating $n^{+}$ zones. This structure reduces the kink-effect drastically and improves the on-current. Due to the separated floating $n^{+}$ zones, the transistor channel region is split into four zones with different lengths defined by a floating $n^{+}$ region. This structure allows an effective reduction of the kink-effect depending on the length of two sub-channels. The on-current of the proposed dual-gate structure is 0.9 mA while that of the conventional dual-gate structure is 0.5 mA at a 12 V drain voltage and a 7 V gate voltage. This results show a $80 {\%}$ enhancement in on-current by adding two floating $n^{+}$ zones. Moreover we observed the reduction of electric field In the channel region compared to conventional single-gate TFT and the reduction of the output conductance in the saturation region. In addition we also confirmed the reduction of hole concentration in the channel region so that the kink-effect reduces effectively.
스트레칭 유형에 따른 인체 골격근의 신경역학적 적응에 관한 연구
이대연(Dae Yeon Lee),이영철(Young Cheol Lee),이해동(Hae Dong Lee) 한국사회체육학회 2013 한국사회체육학회지 Vol.0 No.52
The purpose of this study was to investigate the effect of different stretching type on morphological and neuromechanical properties of human lower leg muscles in vivo. Twenty healthy volunteers(n=20) participated in this study. Prior to and immediately after the stretching exercises, muscle architecture, strength, contractility, activation were simultaneously measured using an integrated system of ultrasonography, dynamometry, elec-tromyography and electrical stimulator. Pennation angle from the results of the analysis of the difference between the before and after stretching, static stretching group, half relaxation time, neuromuscular activation of stretching after significant differences were found(p<.05). However, the dynamic stretching group did not show differences in all the variables be-fore and after exercise. Twitch torque and passive tension in the results of the comparison of the difference according to the type, the fascicle length of the pre-exercise group, there were differences between groups after exercise, pennation angle(p<.05), but that there are differences between groups both before and after the rest of the variables in the stretch type showed no difference between group. In conclusion, the acute effect of static stretching was found to be more pronounced compared with dy-namic stretching, suggesting that the caution and careful prescription might necessary for performance en-hancement and rehabilitation.
추출법에 따른 당귀수산과 작약감초탕의 성분과 활성의 비교
이대연 ( Dae-yeon Lee ),이호성 ( Ho-sung Lee ),조주휘 ( Ju-hwi Jo ),이영우 ( Young-woo Yi ),김성진 ( Sung-jin Kim ),강경래 ( Kyungrae Kang ),권태욱 ( Tae-wook Kwon ),양승구 ( Seung Gu Yang ),이인희 ( In-hee Lee ) 한방재활의학과학회 2020 한방재활의학과학회지 Vol.30 No.4
Objectives Danggwisoo-san and Jakyakgamcho-tang are frequently prescribed for traffic accident patients in Korea. The aim of this study was to examine index compound analysis, antioxidant activity and amount of starch measurement by extraction method. Methods Danggwisoo-san and Jakyakgamcho-tang were extracted with water and 70% ethanol. Antioxidant activity was measured by 2,2-Diphenyl-1-picrylhydrazyl, 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) and ferric reducing antioxidant power according to the standard protocol. The contents of the indicator components nodakenin, paeoniflorin, and glycyrrhizin were measured by high-performance liquid chromatography, respectively. All starches were hydrolyzed and then total D-glucose was measured and compared. Results Antioxidant activity was excellent in 70% ethanol in all assays. The index component was jagged because its solubility was different depending on the extraction solvent. Starch content was significantly lower in 70% alcohol extract than water extract. Conclusions The results of this study showed that physiological activities and components are different according to extraction conditions. Each herbal medicine has a suitable extraction solvent. Also, the difference in starch content is an object to be considered as it may affect digestion and absorption. (J Korean Med Rehabil 2020;30(4):31-39)
이대연 ( Dae-yeon Lee ),조주휘 ( Ju-hwi Jo ),김완수 ( Wan-su Kim ),이호성 ( Ho-sung Lee ),이영우 ( Young-woo Yi ),박상인 ( Sang-in Park ),안건상 ( Keon-sang An ),이인희 ( In-hee Lee ) 한방재활의학과학회 2020 한방재활의학과학회지 Vol.30 No.2
Objectives SJ004 is a natural herbal medicine that contains Acyranthes japonica Nakai and Eucommia ulmoides Oliver traditionally used for joint and spinal diseases. This study aimed to establish an efficient method of extracting SJ004 to standardize using the yield, high-performance liquid chromatography (HPLC), and antioxidant assay. Methods SJ004 was extracted with distilled water, 70% and 100% of ethyl alcohol (EtOH). The method validation of 20-hydroxyecdysone and pinoresinol diglucoside was determined by HPLC-photo diode array and the content of SJ004 was calculated. The antioxidant activity of each extract was compared and measured using total flavonoids, total phenolic compounds, 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), and ferric reducing antioxidant power according to the standard protocol. Results The yield was highest in pure water extract and lowest in 100% EtOH. But, the content of marker compounds indicating 20-hydroxyecdysone and pinoresinol diglucoside was highest in 100% EtOH extract. In the physiological activity measurement using antioxidant activity, 100% ethanol extract was highest. The limit of detection indicating 20-hydroxyecdysone and pinoresinol diglucoside were analyzed 0.33 μg/mL, 0.1616 μg/mL, and the limit of quantification were analyzed 1.01 μg/mL and 0.49 μg/mL respectively. Conclusions The experimental results showed that the extraction conditions have a significant effect on content of marker compounds and antioxidant activity. As a result of method validation, SJ004 was standardized by 20-hydroxyecdysone and pinoresinol diglucoside. (J Korean Med Rehabil 2020;30(2):67-75)