하구 환경관리를 위한 관리구역 경계 설정방안

이강현,조현정,노백호,이창희,Lee, Kang-Hyun,Cho, Hyun-Jeong,Rho, Baik-Ho,Lee, Chang-Hee 한국해양학회 2012 바다 Vol.17 No.4

Definition of estuary and its administrative boundaries is needed for the practical management of estuarine environment. However, the majority of Korean estuaries are lack of scientific data required for defining the administrative boundaries. For this reason, a systematic way to set the boundaries has not been developed so far. This study proposed adaptive and comprehensive criteria in defining the boundary of an estuary based on the available data which includes physiochemical, geographical and topographical characteristics and regional data such as land uses and socio-economic conditions. An estuary boundary is defined with a sequential manner. First of all, according to the estuarine circulation pattern, 463 estuaries in Korea were classified into open estuaries and closed estuaries. Then an individual belonging to each type of estuary is defined an water zone boundary considering the physiochemical, geographical and topographical characteristics and land uses. Finally, a land zone boundary is set along the catchment. According to the proposed criteria, we have delineated 274 estuarine management zones in Korea on a trial basis and found that it was possible to set a boundary reasonably considering the difference of level of available data and regional characteristics in each estuary.

하구의 지형적.자연서식지.이용개발특성에 따른 유형 분류

이강현,노백호,조현정,이창희,Lee, Kang-Hyun,Rho, Baik-Ho,Choi, Hyun-Jeong,Lee, Chang-Hee 한국해양학회 2011 바다 Vol.16 No.2

Classification of estuaries based on their multi-component and multidisciplinary processes is important for the systematic management of estuaries. In this study, an integrated GlS-based analysis system including high resolution aerial photographies and topographic maps was used to classify 463 estuaries based on estuarine circulation pattern, geomorphological feature, natural habitat distribution and characteristics of land use. These estuaries were divided into two basic types, open and closed. Two hundred and thirty five systems were open estuaries comprising of forty one mountainous type (OM), eighty sevcn sandpit type (OS) and one hundred seven funnel type (OF). Each type of open estuary was further classified into three types based on habitat distribution and land use characteristics resulting in total ninc types of open estuaries. Two hundred and twenty eight estuaries were closed systems comprising of one hundred and forty four blocked type (CB directly) and eighty four lake type (CL, indirectly). CB type estuary was further classified into three types based on habitat distribution and land use characteristics. This estuarine classification scheme can be applied to provide a framework for effective management strategies of individual estuaries to estimate the management priority and strategy.

위치추적 센서를 이용한 터널의 실시간 시공관리

이강현,김대원,문성모,조훈희,강경인,이인모,Lee, Kang-Hyun,Kim, Dae-Won,Mun, Sung-Mo,Cho, Hun-Hee,Kang, Kyung-In,Lee, In-Mo 한국터널지하공간학회 2011 한국터널지하공간학회논문집 Vol.13 No.2

Construction sites are becoming larger and complex with the growth of national economy. Accordingly, it is important to identify real-time information about materials, equipments, and manpower during construction at sites. Even though research utilizing position tracking sensors has been conducted in architectural engineering fields, this area of research is almost nil in civil engineering fields. Therefore, a feasibility study to find a way to apply position tracking sensors to an in-situ tunnel construction site adopting conventional tunnelling method is performed in this study. A methodology is proposed that the progress management of the tunnelling work can be monitored by checking construction materials needed at job site and the safety management system can be assessed by checking distance between in-situ workers and construction equipments. The most representative materials were identified so that IT technology can be applied by attaching and monitoring sensors to the selected materials. Also, time of arrival (TOA) for a position determination technology along with a wireless network technology was chosen and build wireless network system. The adopted methodology was applied to an in-situ tunnelling site, and verified the usefulness of the proposed system. 국가 경제규모의 성장과 더불어 단위 건설현장도 대형화, 복합화 되어 가고 있는 추세이다. 이에 따라 건설현장에서는 효율적인 프로젝트 관리를 위하여 자재, 장비, 인력 등의 자원에 관한 실시간 정보파악의 요구가 증가하고 있다. 최근 건축분야에서는 다양한 위치추적 센서를 활용한 시공관리에 대한 연구가 이루어지고 있다. 하지만 토목분야에서는 이러한 연구가 거의 전무한 실정이다. 따라서 본 연구에서는 터널 시공 방법 중 NATM 공법을 대상으로 위치추적이 가능한 센서를 활용하여 자재를 이용한 진도관리와 장비와 인력간의 안전관리에 있어서 실제 현장에 활용 가능한 방법을 제시하였다. 각 공정의 자재를 이용한 진도관리 방안과 사람과 장비의 거리를 통한 안전관리 방안을 제시하였다. 센서를 부착할 진도관리용 자재를 선정하고, 위치좌표를 계산하기 위한 TOA방식의 무선측위기술과 무선랜을 이용하여 터널 현장에 무선 네트워크 시스템을 구축하였다. 이를 바탕으로 터널 현장에 적용 가능한 모델을 제시하였으며, 현장 예비 시험과 현장시험을 통하여 시스템을 검증하였다.

연소 합성 공정을 이용한 Mullite의 합성

이강현,이채현,김택남,김종옥,임대영,박원규,Lee, Kang-Hyun,Lee, Choe-Hyun,Kim, Taik-Nam,Kim, Jong-Ock,Lim, Dae-Young,Park, Won-Kyu 배재대학교 공학연구소 1997 공학논문집 Vol.2 No.1

The conventional process in synthesizing mullite powder required high temperature ($1300^{\circ}C$) and long chemical reaction time. Thus the combustion process was used to synthesize the mullite powder in order to reduce the reaction time and temperature. The mixture of metal nitrate, fine silica, and fuel was used as the redox compounds under various experimental conditions. The combustion fire in hot plate experiment in rich, lean and stoichiometry fuel does not produce mullite. However, the obvious mullite, small amount of alumina and cristobalite was observed in the $500^{\circ}C$ pre-heat treatment furnace experiment. The components such as silica, urea, aluminm nitrate should be stoichiometry in order to make a perfect mullite crystal.

The Effects of 5-benzylacyclouridine on the Cytotoxicities of Fluorinated Pyrimidine Antimetabolic Agents in L5178Y Cells

이강현,차승만,Lee, Kang-Hyun,Cha, Sung-Man The Korean Society of Pharmacology 1990 대한약리학잡지 Vol.26 No.1

The benzylacycoluridines (BAU and BBAU) are potent and specific inhibitors of uridine phosphorylase (UrdPase). In contrast to the report that benzylacyclouridines potentiated 5-fluoro-2'-deoxyuridine (FdUrd) cytotoxicity against human solid tumor cells (Cancer Res., 44:1852, 1984), continuous exposure of mouse lymphoma L5178Y cells, to FdURd, 5-fluorouridine (FUrd), 5'-deoxy-5-fluorouridine (5'-dFUrd), or 5-fluorouracil (FUra) showed no potentiation of cytotoxicity by benzylacyclouridines. In fact, under the conditions employed, benzylacycoluridines protected the cells from the cytotoxicity of FdUrd, FUrd, or 5'-dFUrd, but not FUra in a dose dependent manner. Intraperitoneal coadministration of BAU or BBAU and a 5-fluorinated pyrimidine (i.e., FdUrd, FUrd, or FUra), to mice bearing L5178Y cells also did not significantly increase the life span compared to those treated with the antimetabolites alone. Anabolism of these nucleosides through the sequential action of UrdPase and orotate phosphoribosyltransferase (OPRTase), inhibition of nucleoside transport by benzylacyclouridines, or both could be responsible for the ineffectiveness of UrdPase inhibitors to potentiate the antineoplastic activity of fluoropvrimidines in L5178Y cells. Benzylacyclouridines (BAU and BBAU)는 uridine phosphorylase (UrdPase)의 선택적이고 강력한 상경억제제이다. 보고된 바에 의하면 (Cancer Res., 44: 1852, 1984) Benzylacyclouridines가 5-fluoro-2'-deoxyuridine (FdUrd)의 인체 암세포에 대한 독성을 증가시켜 준다고 하였지만, L5187Y 세포를 사용한 본 실험에서는 Benzylacyclouridines가 FdUrd를 포함하여 5-fluorouridine (FUra) 모두에 대해 조금도 세포 독성을 증가시키지 못하였을 뿐만아니라, 오히려 세포를 그들 독성으로부터 투여량에 비례하여 보호하였다. 복강내 주사에 의한 생체실험에서도 Benzylacyclouridines는 5-fluorinated pyrimidine에 의한 L5187Y를 지닌 쥐(mouse)의 life-span을 연장시켜 주지 못하였다. 본 실험에서 Benzylacyclouridines가 기대했던 fluorinated pyrimidine 항암제의 효과를 증진시키지 못한 이유는 nucleosides의 anabolism이 UrdPase와 orotate phosphoribosyltransferase이 의한 sequential 작용에 의하던가 또는 Benzylacyclouridines에 의한 nucleosides의 수송억제에 의하던가, 아니면 두가지 다 복합적으로 작용한 결과로 생각된다.

전기비저항 검층으로 얻은 전기비저항과 터널 현장 암반등급의 상관관계에 관한 연구

이강현,서형준,박진호,안희윤,김기석,이인모,Lee, Kang-Hyun,Seo, Hyung-Joon,Park, Jin-Ho,Ahn, Hee-Yoon,Kim, Ki-Seog,Lee, In-Mo 한국터널지하공간학회 2012 한국터널지하공간학회논문집 Vol.14 No.5

터널 시공 중 암반등급은 지보패턴의 결정에 큰 영향을 주는 요소이다. 따라서 터널 설계 시에 터널이 시공되는 노선의 암반등급을 파악하기 위해서 시추조사를 수행한다. 시추구간 사이의 미시추 구간에서는 전기비저항 탐사, 탄성파 탐사 등과 같은 지구물리탐사를 통해 암반등급을 파악한다. 따라서 전기비저항과 암반등급의 상관관계를 찾기 위한 연구가 다수 수행되었다. 그러나 대부분의 연구는 실내시험 또는 전기비저항 탐사로부터 얻어진 전기비저항과 암반등급의 상관관계에 대한 연구이다. 따라서 본 연구에서는 현장의 전기비저항 검층 시험으로부터 얻어진 전기비저항과 RMR의 상관관계를 분석하였다. 현장 데이터 분석 결과, 전기비저항과 RMR은 약 90%이상의 매우 높은 상관관계가 있는 것으로 나타났다. 또한 RMR 평가 요소들과 전기비저항의 상관관계 분석을 수행한 결과, 전기비저항과 불연속면상태는 약 80%이상의 양호한 상관관계가 나타났으나 지하수상태는 약 57%이하의 낮은 상관관계가 나타났다. Rock mass rating (RMR) is the key factor when designing the appropriate support pattern of tunnel projects. Borehole drilling is usually performed along the tunnel route in order to determine the rock mass rating to be used for tunnel design. The rock mass rating at the non-boring region between boreholes is usually assessed through geophysical surveys such as electrical prospecting, seismic prospecting, etc. Many studies were carried out to find out the correlation between electrical resistivity and rock mass rating. However, most researches were aimed at obtaining the relationship between the two parameters utilizing experimental results obtained from laboratory tests or electrical prospectings. In this paper, efforts were made to analyze and obtain relationships between the electrical resistivity obtained from in-situ electrical resistivity logging data and the rock mass rating. Correlation studies using field data showed that the electrical resistivity is highly correlated with the rock mass rating with the determination coefficient more than 90%. The correlation analysis was also carried out between RMR classification parameters and the electrical resistivity. It was shown that the correlation between the condition of discontinuities and the electrical resistivity was very high with the determination coefficient more than 80%; that between the groundwater condition and the electrical resistivity was very low with the determination coefficient less than 57%.

3차원 레이저 스캐너를 활용한 터널 시공관리

이강현,허인욱,김도훈,이인모,Lee, Kang-Hyun,Heo, In-Wook,Kim, Do-Hoon,Lee, In-Mo 한국터널지하공간학회 2011 한국터널지하공간학회논문집 Vol.13 No.3

현재 3차원 레이저 스캐너는 게임, 영화, 의료, 미술, 디자인 분야 등 다양한 분야에서 널리 사용되고 있다. 토목분야에서는 교량 및 터널에 3차원 레이저 스캐너를 이용한 시공관리 방안 및 적용에 관한 연구가 다수 수행되었다. 그러나 3차원 레이저 스캐너로 얻어진 데이터의 용량이 너무 크고 우리나라 현장 실정에 적합한 소프트웨어가 없는 것이 현실이다. 따라서 본 연구에서는 3차원 레이저 스캐너의 데이터를 신속하게 처리할 수 있도록 데이터베이스를 구축하였으며, 터널의 미굴 여굴 여부 판단, 균열 누수 백태를 확인할 수 있는 소프트웨어를 개발하였다. 또한 실제 터널 현장에 3차원 레이저 스캐너를 사용하여 3차원 레이저 스캐너와 소프트웨어를 검증하였다. 이는 터널 시공 중 시공관리 및 시공 후 유지관리에도 기여할 수 있을 것으로 예상된다. A 3D laser scanner is widely used in various fields such as games, movies, medicines, art, design, etc. Many studies for utilizing the 3D laser scanner in the fields of civil engineering have also been carried out, for example, for systematically managing tunnel and/or bridge construction. However, since a software which is directly applicable to Korean construction system does not exist, the amount of data obtained from existing the 3D laser scanner is too much to handle in a systematic way. Therefore, in this paper, a new data processing technique was established which can rapidly and effectively treat the 3D laser scanning data. Moreover, a software that can systematically manage the tunnel construction was developed. The developed software can assess the construction quality of tunnel excavation such as under-break, over-break, cracks, leakage and efflorescence, etc. A 3D laser scanner and the developed software was applied to an in-situ tunnelling site, and verified usefulness of the 3D laser scanner. The developed software may be useful for tunnel maintenance as well as for systematic management of tunnel construction.

남성 불임증 환자에 대한 Clomiphene의 효과

이강현,이희영,Lee, Kang-Hyun,Lee, Hee-Yong 대한생식의학회 1981 Clinical and Experimental Reproductive Medicine Vol.8 No.2

Clomiphene citrate. antiestrogen, was given to 39 infertile males whose spermatogenesis were disturbed and the efficacy of the drug was evaluated at the Department of Urology in 1980. (Table 1). Patients were divided into 3 clinical observation groups such as group I composed of 19 cases of idiopathic azoospermia, group II consisted of 15 cases of oligospermia following the vasovasostomy, and group III comprised 5 cases of testicular azoospermia. (Table 2). Clinical characteristics of these patients were as follows: Age of the patients ranged from 26 to 43 years old with mean of 34, and that of their wives ranged from 24 to 41 years old with mean of 31. Duration of marital life ranged from 1 to 21 years with mean of 5 years. Sizes of testis ranged from 6 to 25 ml with mean of 16 ml. Coital frequency ranged from 0.5 to 6 per week with mean of 2.4 per week. Levels of plasma FSH ranged from 3.15 to 23.06 lU/1 with mean of 8.15 lU/1, those of LH ranged from 2.98 to 19.89 lU/1 with mean of 8.18 lU/1 and those of testosterone ranged from 3.09 to 9.97 ng/ml with mean of 6.48 ng/ml. (Table 3). Clomiphene citrate was given in dosage of 50 mg per day (in d.) orally to 31 patients for 3 to 9 months and in dosage of 100 mg per day (b.i.d.) orally to 8 patients for 3 to 9 months. (Table 8). Semen samples were analysed monthly on each patient by routine analysis techniques. For the assessment of the efficacy of Clomiphene citrate on faulty spermatogenesis following empirical criteria were used: For semen quality: Improvement (I) represents that semen parameter increased more than 25% from basal level after the treatment, Unchange (U) expresses that semen parameter increased less than 25% of basal level or not changed after the treatment and Deterioration (D) means that semen parameter decreased from basal level after the treatment. For fertility unit (total counts ${\times}$ motility ${\times}$ morphology ${\div}10^6$): Improvement (I) represents that fertility unit increased more than 10 units after the treatment, Unchange (U) expresses that fertility unit increased less than 10 units or not changed after the treatment, and Deterioration (D) means that fertility unit decreased after the treatment. (Table 4). Results obtained from the Clomiphene therapy were as follows: Changes of spermiograme before and after the Oomiphene therapy shown in the Table 5. Sperm counts increased from 23 to 31 ${\times}10^6$/ml in group I, from 17 to 29 ${\times}10^6$/ml in group II. Other parameters of spermiogramme were not changed significantly after the treatment. Fertility units increased from 14 to 18 units after the treatment in group I, and from 16 to 18 units after the treatment in group II. Effectiveness of Clomiphene citrate on spermatogenesis was summarised in the Tables 6 and 7. After the treatment, sperm count increased in 11 patients, motility increased in 6 patients, morphology increased in 4 patients and fertility units increased in 9 patients. No sperm could be produced by Clomiphene citrate in group III of testicular azoospermia. Dosage of 50 mg of Clomiphene citrate per day for 3 to 6 months was proved to be the most effective in the present series. (Table 8). Pregnancy occurred in 2 patients after the treatment. No particular side effects were noted by the treatment. Pharmacologic compounds used for male infertility were shown in the Table 9. Reported results of Clomiphene citrate were shown in the Table 10.

암반터널 안정성 평가를 위한 손상제어실험 기반의 한계변형률에 관한 연구

이강현,김도훈,박정준,이인모,Lee, Kang-Hyun,Kim, Do-Hoon,Park, Jeong-Jun,Lee, In-Mo 한국터널지하공간학회 2011 한국터널지하공간학회논문집 Vol.13 No.6

일반적으로 터널 시공현장에서는 계측된 천단 및 내공변위와 계측관리기준을 비교하여 터널의 안정성을 판단한다. 현재 계측관리기준은 지반조건, 터널단면의 크기, 시공방법, 지보재량 등을 고려한 경험을 통해 세워지고 있는 실정이다. 따라서 새로운 계측관리기준으로 한계변형률을 이용하는 방법에 대한 연구가 다수 수행되었다. 그러나 대부분의 연구는 일축압축강도실험에서 얻어진 한계변형률을 기준으로 삼고 있어 실제 터널 굴착 시 발생하는 응력의 증가 및 종방향 아칭에 의한 암반 손상을 고려하지 않는 문제점을 가지고 있다. 따라서 본 연구에서는 국내 대표 암종인 화강암과 편마암의 한계변형률 특성을 조사하기 위하여 일축압축강도실험과 응력의 증가 및 종방향 아칭을 고려한 손상제어실험을 수행하였다. 손상제어실험에서 얻어진 한계변형률은 일축압축강도실험에서 얻어진 한계변형률보다 다소 작게 나타났다. 이는 일축압축강도실험에서 얻은 한계변형률은 터널 굴착 시의 응력이력을 고려하여 다소 감소시켜야 한다는 것을 의미한다. 또한 대심도 터널에서 흔히 발생하는 취성파괴를 평가하기 위한 손상한계변형률을 제안하였다. In general, the tunnel stability during excavation is assessed by comparing measured displacements at roof and sidewall to control criteria. The control criteria were established based on the past experience that considered ground conditions, size of the tunnel cross section, construction method, supports, etc. Therefore, a number of researches on the control criteria using the critical strain have been conducted. However, the critical strain obtained from uniaxial compression tests have drawbacks of not taking damage in rock mass due to increase of stress level and longitudinal arching into account. In this paper, damage-controlled tests simulating stress level and longitudinal arching during tunnel excavation were carried out in addition to uniaxial compression tests to investigate the critical strain characteristics of granite and gneiss that are most abundant rock types in Korean peninsula. Then, the critical strains obtained from damage-controlled tests were compared to those from uniaxial compression tests; the former showed less values than the latter. These results show that the critical strain obtained from uniaxial compression tests has to be reduced a little bit to take stress history during tunnel excavation into account. Moreover, the damage critical strain was proposed to be used for assessment of the brittle failure that usually occurs in deep tunnels.

치주포대에 클로르헥시딘 이용형태가 치주수술후 임상과 미생물학적 변수에 미치는 영향

이강현,김성호,신형식,Lee, Kang-Hyun,Kim, Sung-Ho,Shin, Hyung-Shik 대한치주과학회 1994 Journal of Periodontal & Implant Science Vol.24 No.2

A study was conducted to compare the effects of chlorhexidine mouthrinse and chlorhexidine acetate powder with periodontal pack during 4 weeks following periodontal surgery. Twelve patients were treated with Modified Widman flap procedures and devided into three groups of four patients each; control group, chlorhexidine mouthrinse group, chlorhexidine acetate powder group. Each group wasn't significant difference in clinical and microbiologic parameters at preoperation. Examination regarding plaque index, gingival index, pocket depth, change of gingival color postsurgically, pain index were performed by each methods and observed bacteria in gingiva by phase contrast microscope. Evaluations were made at 7, 14 and 28 days postsurgically. The results were as follows: l. In comparison of results revealed no significant differences in Plaque Index, Gingival Index, pocket depth and change of gingival color postsurgically. 2. The pocket depth of three experimental groups were significant reduced at 4 weeks. 3. Chlorhexidine mouthrinse group and chlorhexidine acetate powder group with periodontal pack were significant differences in pain index at 3, 4 days postsurgically. 4. Cocci and Non-motile rods were increased at 1, 2 weeks. But, motile rod and spirochete were increased at 4 weeks.