선형 동작하는 In-Plane 멤즈형 광학 가변 필터

윤성식,이종현 한국통신학회 2002 한국통신학회 기타 간행물 Vol.2002 No.10

사물제통탕(四物除痛湯)이 Taxol 처리 및 좌골신경 압좌 손상 후 신경조직 변화에 미치는 영향

윤성식,김철중,조충식,Youn, Sung-Sik,Kim, Chul-Jung,Cho, Chung-Sik 대한한방내과학회 2012 大韓韓方內科學會誌 Vol.33 No.2

Background : Peripheral nerves more rapidly recover than central nerves. However, it has been known that the degree of reaction of axons of peripheral nerves is affected by distinctive characteristics of axons and environmental factors near the axons. Taxol is a widely used medicine as for ovarian, breast, lung and gastric cancer. However it causes patients difficulties under treatment due to its toxic and side effects, which include persistent pain. Objectives : This study reviewed how SJT extract in vitro and in vivo affects nerve tissues of a sciatic nerve damaged by Taxol. It also studied how SJT extract in vivo affects axons of the sciatic nerve after the sciatic nerve was damaged by pressing. Methods : After vehicle, Taxol, and Taxol plus SJT were treated respectively for tissue of the sciatic nerve in vitro and then tissues were observed using Neurofilament 200, Hoechst, ${\beta}$-tubulin, $S100{\beta}$, caspase-3 and anti-cdc2. SJT was also oral medicated by injecting Taxol into the sciatic nerve of in vivo rats. Tissues of the sciatic nerve and axons of DRG sensory nerves were then observed using Neurofilament 200, Hoechst, ${\beta}$-tubulin, $S100{\beta}$, caspase-3 and p-Erk1/2. After inflicting pressing damage to the sciatic nerve of in vivo rats, tissues of the sciatic nerve and DRG sensory nerve were observed using Neurofilament 200, Hoechst, $S100{\beta}$, caspase-3, anti-cdc2, phospho-vimentin, ${\beta}1$-integrin, Dil reverse tracking and p-Erk1/2. Results : The group of in vitro Taxol plus SJT treatment had meaningful effects after sciatic nerve tissue was damaged by Taxol. The group of in vivo SJT treatment had effects of regenerating Schwann cells and axons which were damaged by Taxol treatment. The group of in vivo SJT had effects of regenerating axons in damaged areas after the sciatic nerve was damaged by pressing, and also had variations of distribution in Schwann cells at DRG sensory nerves and axons. Conclusions : This study confirmed that SJT treatment is effective for growth of axons in the sciatic nerve tissues and improvement of Schwann cells after axons of the sciatic nerve tissues was damaged. After tissues of sciatic nerve was damaged by pressing in vivo, SJT treatment had effects on promoting regeneration of axon in the damaged area and reactional capabilities in axons of DRG sensory nerves.

소비의 경상적지출과 자본적지출에 대한 불교적 관점

윤성식 한국불교학회 2013 韓國佛敎學 Vol.66 No.-

If buddhism can solve the suffering due to money, it would certainly resolve modern man’s suffering due to spending. Once you see people enthusiastic about nonpossession, it doesn’t seem to be unnatural to pursue the solution regarding suffering from money. The expression, ‘spending is a virtue’, is widely accepted in that mass consumption came to reality after industrial revolution and capitalism is full-blown. Overconsumption is not only detrimental to self but also to society. Buddhist economic principle of spending is proper spending according to one’s due which is middle path. Buddhist economic principle of spending in middle path is applied flexibly within Buddhist community. More strict spending rule applies to practitioners at the temple than to lay people. Moreover, bhikkhuni is allowed to wear more elegant garments than bhikkhu in the Buddhist priesthood. Spending rules applied to practitioners at the temple seem to be ascetic, it is moderate compared to Jainism and Devadatta’s arguments. Buddhist economic principles of spending require human beings to practice buddhist meditation to escape from suffering due to desires and addictions. However, Buddhism tries fundamentally to block temptation originating from spending objects by restricting and devaluing them. Operational expenditure ought to be restraint oriented compared to capital expenditure. Since operational expenditure has characteristics as a spending, restraint is a virtue. By contrast, capital expenditure has characteristics as an investment, active investment is a virtue. Donation is understood as a tool to acquire happiness, therefore, it is considered to be capital investment. Spending for the sake of images and signals cultivates tastes resulting into accumulation of cultural capital, hence, it can be classified as a capital investment. Sutra’s clauses that husband should give his wife ornaments and bhikkhuni is welcome to wear more good garments are evidences of Buddhism’s willingness to allow more generous spending level than minimal level of consumption to maintain life. 불교가 재물로 인한 고통을 해결할 수 있다면 소비로 인한 현대인의 고통에도 해결책을 제시해야 한다. 오늘날 사람들이 무소유에 열광하는 것을 보면 불교로부터 소비에 관한 고통의 해결책을 찾는 것이 그다지 부자연스럽게 보이지는 않는다. 산업혁명 이후 대량 소비가 가능해지고 자본주의가 본격화되면서 소비가 미덕이라는 말은 상당히 당연한 말로 받아들여지게 되었다. 과잉 소비는 자기에게도 문제이지만 사회에도 많은 손해를 끼친다. 소비에 관한 불교경제학적 원칙은 분수에 맞고 적정한 중도적 소비이다. 중도적 소비 원칙은 불교 내에서 유연하게 적용되고 있다. 재가자보다 출가자에 대해서 보다 엄격한 원칙이 적용되며 승가내에서도 비구니에게는 좋은 옷을 허용하였다. 출가자에 적용된 소비원칙은 금욕적으로 보이지만 자이나교나 제바달다의 주장에 비교하면 중도적이라고 볼 수 있다. 불교의 소비에 대한 원칙은 소비의 주체인 인간에 대해서는 욕망과 집착에서 벗어나기 위해 수행할 것을 요구한다. 그러나 불교는 이에 그치지 않고 소비의 객체를 제약하거나 훼손 시켜서 소비에 대한 유혹을 원천적으로 차단하려고 노력한다. 경상적 지출은 자본적 지출에 비해 보다 절제지향적이 될 수밖에 없다. 경상적 지출은 소비의 특성을 가지고 있어 절제가 미덕이지만 자본적 지출은 투자의 특성을 가지고 있어서 과감한 지출이 미덕이다. 보시는 복전 사상으로 인하여 경상적 지출이 아닌 자본적 지출로 이해될 수 있다. 이미지와 상징을 위한 소비는 취향을 길러주어 문화자본을 축적하므로 자본적 지출에 해당된다. 장식품을 아내에게 주고 비구니는 좋은 옷을 입어야 한다는 내용으로부터 불교가 생명의 유지를 위한 최소한의 소비만을 허용한 것은 아니라는 해석이 가능하다.

상태 추정을 이용한 pH 공정의 비선형 제어

윤성식,윤태웅,강태식 제어로봇시스템학회 1999 제어로봇시스템학회 국내학술대회 논문집 Vol.4 No.10

궤환선형화 가능한 비선형 시스템의 입력제한을 고려한 동적 와인드엎 방비

윤성식,박종구,윤태웅 제어로봇시스템학회 2000 제어로봇시스템학회 국내학술대회 논문집 Vol.1 No.10

전문대학 식품영양과의 실험실습 및 현장실습 운영실태에 관한 연구

윤성식,소명환,남궁석 한국식품영양학회 1989 韓國食品營養學會誌 Vol.2 No.1

This study was conducted to gather the baseline data on realities of experimental-practice and opinions toward spot-practice, and to examine how to cope with the problems raised at the Department of Food and Nutrition of Junior Technical College in Korea. Ouestionairs were gathered from 42 chairmans of the Department of Food and Nutrition and 140 present dieticians worked in Seoul, Bucheon and Seongnam area. The results are as follows, First, as a whole, each college had 2∼3 experimental laboratory (Lab), in which Cooking Science Lab, Chemistry Lab and Microbiology Lab were occured at higher frequency as Lab's name. Second, the numbers per experimental-practice class were more than 40 at most colleges. 85% of present dieticians have answered to feel too much numbers per the class during their college days, whereas professors' opinions toward the numbers per class were suitable at 20∼30 persons per class. Third, professors' opinion toward the adquate ratio of the theory subject classes to experimental subject classes was suitable at 60 : 40. Dieticians answered to take the theory subject classes partly or mostly on behalf of the experimental-practice classes. Fourth, the main reasons which inhibited normal experimental-practice class were the class for emphasis on examination, the shortage of experiment budget, the excess of class members, the shortage of experimental Lab. Also, this results showed same propensity to present dieticians' opinion toward the same question above. Fifth, among the experimental-practice subjects established at the Department of Food and Nutrition, Diet Therapy Lab was highest frequency class emphasized on theory followed by Nutrition Counselling Lab, Food Processing and Storage Lab, Food Hygiene Lab and Food Microbiology Lab in that order. Here, Basic Chemistry Lab, Biochemistry Lab, Food Microbiology Lab were pointed as subjects far from the present task of dieticians. Sixth, Department of Food and Nutrition, as a whole, has conferred with spot-practice arrangement. About 50% (all who want to join spot-practice) of second year students took part in spot-practice. In the other way, all colleges except for 2 colleges didn't give the credit for the spot-practice system. Seventh, according to the on analysis on spot-practice places, manufacturing company was at highest frequency followed by hospitals, elementary school having group feeding system in that order. Especially, 16.7% (5 colleges) of the total colleges sent the students to the research institute related to food industry for spot-practice experience. Eighth, Professors' opinions toward the spot-practice time and periord were preferable on summer vacation of second year and for 1∼2 weeks, respectively. On the contrary, 74 dieticians answered to the adquate period as for 4 weeks. Ninth, 86 dieticians of the total 140 answered to complete the spot-practice during their college days, which helps the present task of them. Lacks of spot-practice program, Lacks of comprehension of upper personnels and lacks of group feeding equipments ranks higher as difficulties in spot-practice management.

유산균 유전학 및 최근 연구 혁신: 프로바이오틱스와 면역

윤성식,박영서,최학종 한국유산균·프로바이오틱스학회 2013 Current Topic in Lactic Acid Bacteria and Probioti Vol.1 No.1

As for probiotics, that is generally defined as a live cell supplement which is able to bring health benefits to their hosts, even though the concept is still remains in controversy. Scientific works has given positive answers to the questions about if many LAB strains function as probiotic bacteria in human and animals. Currently, the interactions between human and LAB are actively investigated in human intestine. From a biodiversity perspective, this particular subject in human intestine is also extensively explored by a number of researchers worldwide. So far, it has been found that new strains and new genes were discovered in gut microbiota which is reported unique in individual. Complete analysis on gut microbiota is necessary in order to understand the possible beneficial roles of LAB in human intestinal track. When it comes to qualification, a probiotic strain is proved to be safe to consume and healthful to human after it is orally administered. On the other hand, LAB is present as a member of gut microbiota, plays an important role in innate immunity and acquired immunity. Their immune-modulation activity is occurred not only in intestine but also systemic in human body. It is generally accepted that immune function by LAB is not genus-specific but strain-specific. More recently, new mechanism accounting for interactions between host and LAB has been understood after a soluble factor from LAB was found to be directly associated with the epidermal growth factor receptor (EGFR) on intestinal epithelial cells. The soluble factor could be applied in the development of therapeutic agents. In conclusion, future research focus should be placed on the studies on the new LAB factors affecting human immune responses and its desirable effects because many different kinds of fermented foods representing kimchi have survived for a long time and those are popularly consumed in this country.

예산개혁과 정부회계 -발생주의예산과 발생주의회계를 중심으로-

윤성식 한국정책학회 2004 韓國政策學會報 Vol.13 No.2

21세기 혁신국가를 만들자 - 비전과 콘텐츠가 있는 정부혁신 -

윤성식 한국자치발전연구원 2004 자치발전 Vol.2004 No.12

한국인 아동에서의 IL-1 유전자 다변성 연구

윤성식,정현주,김옥수,양규호,Yoon, Seong-Sik,Chung, Hyun-Ju,Kim, Ok-Su,Yang, Ku-Ho 대한치주과학회 2005 Journal of Periodontal & Implant Science Vol.35 No.2

The severe form of chronic periodontitis(CP) has been reported to be strongly associated with the presence of allele 2 of composite IL-1B(+3954) and IL-1A(+4845) genetic polymorphisms(genotype positive). However, other studies have reported conflicting findings. These might have resulted from differences in ethnic background and disease entities. The aim of this study was to determine the distribution of IL-1A(+4845), IL-1B(+3954), IL-1B(-511), and IL-1 RN(VNTR) genetic polymorphisms in children as a future Korean population. The study population consisted of 92 children from the Dept. of Pediatric Dentistry, Chonnam National University Hospital. Genomic DNA was obtained from buccal swab. The IL-1A(+4845), IL-1B(+3954), and IL-1B(-511) genes were genotyped by amplifying the polymorphic region using multiplex polymerase chain reaction(PCR), followed by restriction enzyme digestion and gel electrophoresis. IL-1 RN(VNTR) polymorphism were then evaluated by PCR amplification and fragment size analysis in agarose gel. The allele 2 frequency was 41.3%, 4.3%, 47.8%, and 9.9% for IL-1A(+4845), IL-1B(+3954), IL-1B(-511), and IL-1 RN respectively. The frequency of genotype with allele 2 carriage for IL-1A(+4845), IL-1B(+3954), IL-1B(-511), and IL-1 RN was 77.1%, 7.6%, 63.0%, and 15.2% respectively. The allele 2 frequency in IL-1B(+3954) was significantly higher in female than in male population(p<0.05). The negative association was shown between the presence of allele 2 in IL-1B(-511) and in IL-1B(+3954), and the carriage rate of IL-1B(+3954) allele 2 tended to lower in IL-1B(-511) allele 2(P=0.056). Only 7.3% of children carried the composite genotype of IL-1A(+4845) and IL-1B(+3954). These results suggest that the polymorphism of IL-1B(+3954) and the positive composite genotype was relatively rare in Korean population.