Neoadjuvant Imatinib in Locally Advanced Gastrointestinal Stromal Tumors of the Stomach: Report of Three Cases

오지선,Jae-Lyun Lee,김미정,Min-Hee Ryu,Heung Moon Chang,Tae Won Kim,Se Jin Jang,Jeong Hwan Yook,Sung Tae Oh,Byung Sik Kim,Yoon-Koo Kang 대한암학회 2006 Cancer Research and Treatment Vol.38 No.3

Neoadjuvant imatinib therapy used to treat locally advanced or metastatic gastrointestinal stromal tumors (GI ST) remains under active investigation. We studied three cases of locally advanced gastric GISTs treated with imatinib on a neoadjuvant basis, followed by a complete surgical resection. Three patients were diagnosed with locally advanced unresectable GIST of the stomach and were started on imatinib 400 mg/day. After the imatinib treatment, partial responses were achieved in all patients and the tumors were considered resectable. Surgical resection was done after 7, 11, and 8 months of imatinib therapy, respectively. In one case, a metastatic liver lesion was detected during the imatinib treatment using computed tomography scans, so the imatinib therapy was maintained for 11 months postoperatively. In the other two patients without distant metastasis, imatinib treatment was not restarted after surgery. Mutational analysis revealed a mutation in exon 11 of the c-kit gene in two patients, and wild-type c-kit and PDGFRA in one patient. During pathology review of all three cases, we noted several features common to imatinib treatment. There was no evidence of tumor recurrence in all three patients at respective follow-up visits of 22, 15, and 7 months. These results suggest that the neoadjuvant imatinib therapy is a potentially curative approach for selected patients with locally advanced GIST. (Cancer Res Treat. 2006;38:178-183)

노인요양시설에 근무하는 요양보호사의 직무스트레스가 노인학대에 미치는 영향: 마음챙김과 정서조절곤란의 이중매개효과

오지선(Oh, Ji-Sun),이준영(Lee, Jun-Young) 한국사회복지행정학회 2021 한국사회복지행정학 Vol.23 No.3

전신홍반루푸스 환자의 두개골에 발생한 형질세포육아종

오지선 ( Ji Seon Oh ),권귀영 ( Gui Young Kwon ),소민욱 ( Min Wook So ),최성호 ( Seong Ho Choi ),김용길 ( Yong Gil Kim ),나성수 ( Seong Su Nah ),이창근 ( Chang Keun Lee ),문희범 ( Hee Bom Moon ),유빈 ( Bin Yoo ) 대한류마티스학회 2006 대한류마티스학회지 Vol.13 No.4

Plasma cell granuloma, a form of inflammatory pseudotumor, is a rare nonneoplastic lesion that is characterized by cellular proliferation composed predominantly of polyclonal plasma cells with other inflammatory cells in fibrovascular background. We have experienced an unusual case of plasma cell granuloma of skull that developed in a patient with systemic lupus erythematosus (SLE). A 42-year-old female diagnosed with SLE 13 years ago has complained of palpable scalp mass and headache beginning ten days previously. A brain magnetic resonance imaging showed intensely enhanced soft tissue mass with focal bone defect in right parietal bone and whole body positron emission tomography suggested high possibility of malignancy. Surgical tumor removal was performed. Biopsy specimen revealed inflammatory proliferation predominantly with mature plasma cells which were determined to be polyclonal in immunostaining. Currently, 4 months after surgery, the patient are on regular follow-up with oral medications (prednisolone, hydroxychloroquine) for SLE without evidence of recurrence.

어린이집 교사들의 경력차이에 따른 팀티칭 경험

오지선 ( Oh Ji Sun ),박은영 ( Park Eun Young ) 한국아동교육학회 2016 아동교육 Vol.25 No.3

본 연구는 팀티칭을 하고 있는 어린이집 교사들 간의 경력차이가 있는 초임교사와 경력교사의 팀티칭 경험뿐만 아니라 동일한 경력의 교사들이 함께 팀티칭을 했을 때의 경험을 알아봄으로써 효과적인 팀티칭 학급운영방안을 모색하기 위한 시사점을 제공하고자 한다. 이를 위해 팀티칭을 하고있는 교사 13명을 대상으로 개별면담을 실시하여 분석한 결과 첫째, 경력 차이가 있는 교사 간 팀티칭 경험은 초임교사에게 낯설고 새로운 환경 속에서 부담감과 심리적 위축감을 느끼는 반면 경력교사의 피드백을 통해 교사로서 성장하고 발전할 수 있는 기회가 되는 것으로 나타났다. 한편, 경력교사에게는 초임교사의 모델링이 되어주어야 한다는 부담감과 함께 초임교사와의 의사소통과정에서어려움을 느끼는 반면 자신을 성장시키는 발판이 된다고 생각하는 것으로 나타났다. 둘째, 경력차이가 없는 동일한 경력교사 간 팀티칭 경험은 심리적 안정감 속에 자유롭고 원활한 의사소통과 협력이 이루어지는 반면 경력이 많은 교사의 부재에 따른 어려움과 경쟁으로 인한 심리적 갈등상황이 일어나는 것으로 나타났다. 본 연구의 결과는 현장에서의 다양한 팀티칭에 대한 지속적인 연구와 함께 팀티칭 교사 간 의사소통에 대한 문제를 해결하기 위한 사전교육이 필요함을 시사한다. This study set out to investigate daycare center teachers`` team teaching experiences between beginning and experienced teachers and also among the teachers of the same year of their career; thus, providing implications for the search of effective plans to run a team teaching class. For these purposes, the study conducted an individual interview with 13 teachers that provided team teaching instructions and analyzed their responses. The findings were as follows: first, there were differences in their team teaching experiences according to career. The beginning teachers had a sense of burden and psychological withdrawal in a new and strange environment and, at the same time, found an opportunity of growing and developing as teachers through the feedback of experienced teachers. The experienced teachers had a sense of burden with becoming a role model for beginning teachers and difficulties with communicating with them and, at the same time, took it as a foothold for their growth. Secondly, the teachers in the same year of their career had team teaching experiences characterized by free and smooth communication and cooperation based on psychological stability and also by difficulties due to the absence of experienced teachers and psychological conflicts caused by competition. These findings imply a need for ongoing research on various forms of team teaching in the field and prior education to solve communication problems between teachers of team teaching

CPU-GPU 컨테이너 클러스터의 프로파일링을 활용한 계산응용 실행 계획 기법

오지선(Jisun Oh),김세진(Sejin Kim),김윤희(Yoonhee Kim) Korean Institute of Information Scientists and Eng 2019 정보과학회논문지 Vol.46 No.10

As heterogeneous clusters and cloud environments have gained popularity, selection of appropriate resources in an integrated environment is considered essential for enhancement in application performance with reasonable resource utilization. Application characteristics may require specific resource in a certain order during its execution and ask smart job deployment among diverse nodes. Especially, it is necessary to have an execution plan in advance for better performance of CPU and GPU container clusters. In this paper, we propose an execution planning scheme based on runtime profiling history to place jobs on CPU-GPU nodes. Computational applications usually show good performance in GPU. However, the lack of GPU sharing methods leads to failure of co-locating jobs on a GPU node. Based on the profile information, the scheme provides the combination of applications to run at the same time in GPU container clusters and estimate the performance of workload before executing application among CPU-GPU container clusters. We have also demonstrated adjustment of the order of application execution using profile history in order to reduce the execution time of total workload by monitoring GPU memory usage.

한국 기혼여성창업가의 경영방식에 대한 사례연구: 가정과 일 병행전략을 중심으로

오지선 ( Jee-sun Oh ),김영환 ( Young-hwan Kim ) 한국중소기업학회 2016 中小企業硏究 Vol.38 No.4

본 논문은 사례조사를 통해 여성의 창업활동을 살펴보고 여성의 기업가정신과 생존전략을 분석하는 것을 목적으로 한다. 여성창업가들은 남성중심적인 창업 생태계 내에서 여성 특유의 다양한 전략으로 창업 시 맞닥뜨리는 애로점들을 극복하고 있었다. 또한 여성특유의 공감능력으로 구성원들의 뜻을 하나로 수렴하고, 각자의 능력과 팀워크를 최대한 끌어내는 부드러운 리더십을 발휘하고 있었다. 재정적·물리적·인적 자원이 부족한 사례자들은 사업의 규모를 최소화하여 창업을 하였고, 과거 근무했던 기업 혹은 창업했던 경험을 활용하였다. 무엇보다 여성창업가들은 여성으로서의 삶과 경험을 통해 얻은 생활 밀착형 아이디어를 사업화하여 창업함으로써 남성이 포착할 수 없는 여성 특유의 섬세함으로 창업아이디어를 창출하며 창업 생태계에 긍정적인 영향을 미치고 있다. 여성창업가들은 자신의 기업 활동을 통해 여성고용 창출 및 여성 친화적 기업문화를 만들어 일과 가정 양립의 부담을 여성과 남성, 사회와 조직이 함께 공유하고자 노력하고 있었다. 여성채용에 호의적이었고, 여성들의 재취업이나 창업을 돕고자 했다. 자신과 같은 어려운 조건에서 창업을 하고 있는 또 다른 여성창업가들과 활발한 네트워킹을 하고 있었다. 후배 창업가들에 대한 조언과 지원을 위해 노력하는 모습도 보였다. 여성창업가들은 여성고용창출 뿐 아니라 여성의 사회 재진입을 위해 적극적인 노력을 기울임으로써 국내 창업생태계에 긍정적인 영향력을 파급시키고 있었다. This paper aims to analyze the gender entrepreneurship and survival strategy by reviewing the cases of women entrepreneurship. In a male-dominated ecosystem, women entrepreneurs are mostly challenged in starting their business, but they have overcome those difficulties through women`s unique strategies. Women`s empathy, a form of gentle leadership, could draw the colleagues` capabilities and thus motivate cohesion in a better way. Some entrepreneurs who were lack of physical, financial or human resources tried to optimize their business plan by; minimizing the project scale, applying past working experiences. Through these strategies, women entrepreneurs maximize their chances to enter the market. In the market, women entrepreneurs better commercialize the ideas of life matters that men usually cannot come up with, so that they bring unique and innovative changes in the business ecosystem. Women entrepreneurs have promoted a female-friendly culture and encouraged men and society to pursue work-life balance that used to be the burden of working women. They are active in hiring female employees, and in helping start-up business or re-employment of women though social networking. They also show strong passion to advise and support younger generation to run start-ups. In this regard, women entrepreneurs have proved themselves to be positively influential to Korea`s entrepreneurial ecosystem by creating jobs as well as leading other women to reenter society and enjoy their rights.

모바일에서 콘텐츠 제공 유형 차이에 따른 이용자 태도 분석 - 행정기관 정책 홍보 콘텐츠를 중심으로 -

오지선 ( Oh Ji-seon ),김종무 ( Kim Jong-moo ) 커뮤니케이션디자인학회(구 시각디자인학회) 2018 커뮤니케이션 디자인학연구 Vol.65 No.-

인터넷 기술이 발전하고 스마트폰 보급이 확대되면서 손 안에서 필요한 정보를 찾는 이용자들이 늘고 있다. 지난 2017년 언론수용자 의식조사 보고서에 따르면 모바일로 인터넷을 이용한다는 비율이 80%를 넘어섰고 모바일을 통해 콘텐츠를 소비한다는 비율은 6년 만에 무려 53.7% 급상승한 73.2%를 기록하였다. 모바일 콘텐츠는 이동성이 편한 스마트폰이라는 기기를 통해 정보를 제공하기 때문에 편리성이 높고 정보와 오락의 요소가 더해진 인포테인먼트 요소가 강해 쉽게 다가갈 수 있으며, 이용자들 간의 원활한 커뮤니케이션이 가능해 전 연령층에서 소비하고 있다. 이와 같은 장점으로 모바일 콘텐츠의 양이 나날이 방대해지고 있는 가운데 소비자들은 내게 꼭 필요한 콘텐츠를 찾아내기 위해서 콘텐츠 큐레이션(필요한 정보만 수집·분류·구성하는 과정)을 서슴지 않는다. 이런 변화에 따라 콘텐츠 제작자는 이용자들의 마음을 사로잡기 위해서 어떤 내용을 전달하는 것도 중요한 일이지만 그 내용을 어떠한 형태로 전달할지에 대한 고민도 함께 이뤄져야한다. 본 연구에서는 모바일 플랫폼에서 많이 사용되고있는 스토리텔링(텍스트)형, 인포그래픽형, 동영상형 콘텐츠 유형에 대한 이용자 태도에(호감도, 몰입도, 신뢰도, 만족도) 차이가 어떠한지를 알아보고자, 2018년 04월 09일부터 23일까지 15일간 총 400부의 설문지를 배포하였다. 이 중 회수된 설문지는 385부였고, 불성실한 응답을 한 3부를 제외한 총 382부를 최종 결과 분석에 사용했다. 그 결과 호감도, 몰입도, 신뢰도 및 만족도 모두가 유의한 차이가 없는 것으로 나타났다. 이는 모바일에서 행정기관 정책 홍보 콘텐츠 유형이 이용자 태도에 큰 영향을 주지 않는다는 것이다. 본 연구는 모바일 플랫폼에서 행정 기관 정책 콘텐츠 유형에 관한 연구가 많이 이뤄지지 않은 시점에서 정보 제공 형태가 이용자 태도에 크게 영향을 미치지 않는다는 점을 검증한 것에 의의를 둘 수 있으며, 행정기관에서 모바일 콘텐츠를 제작하고 편집하는 실무자들에게 도움이 되었으면 한다. As Internet technology is developed and smart phones become prevalent, people tend to look for information just on the palm of their hands. In 2017, according to media recipient’s recognition analysis report, Internet usage level through mobile already exceeded 80% and contents usage through mobile also recorded to be 73.2% by rising 53.7% in 6 years. Mobile contents are convient to use because of high mobility and it has infotainment characteristics by adding both information and entertainment and it allows people to communicate with each other so all generations are actively consume mobile contents. Based on these strength points, mobile content’s quality is getting better and quantity is also widening. Consumers also would like to go through all kinds of process such as collecting, sorting and analyzing which is contents curation to look for what they would like to find. In this research, analyzed the difference in user’s attitude(favorable impression, immersion in contents, reliability, satisfactory level) based on different types of contents such as story-telling type, info-graphic type and video type. I started survey from 2018. 04. 09 to 2018. 04. 23 for 15 days with 400 pages of survey papers. Among the 400 survey papers, 385 were returned and after excluding half-hearted 3 survey papers, I used 382 survey papers in analysis for final result. In conclusion, there is no difference in recognition level for favorable impression, immersion, reliability and satisfactory level in statistically significance level. Based on this result, it clearly show that there is no significance impact on user’s attitude based on government’s policy promotional contents type. This research is meaningful for verifying that content type has less impact on user’s attitude when there is not many research covering governmental policy content type under mobile based platform. I also hope that this research can help government officers who make and modify mobile contents.

응급실에 내원한 둔상환자의 수혈 필요성 예측인자

오지선 ( Ji Sun Oh ),김형민 ( Hyung Min Kim ),최세민 ( Se Min Choi ),최경호 ( Kyoung Ho Choi ),홍태용 ( Tai Yong Hong ),박규남 ( Kyu Nam Park ),소병학 ( Byung Hak So ) 대한외상학회 2009 大韓外傷學會誌 Vol.22 No.2

Purpose: In multiple blunt trauma patients, transfusion may be a significant therapeutic adjunct to non-operative management. The blood products must be expedited and efficiently to patients in impending shock caused by hemorrhage or traumatic coagulopathy, but the decision to perform blood transfusion has been made empirically, based on the clinician`s and has not been guided by objective parameters, but own opinion, that may result in an underestimate of or a failure to detect bleeding, in delayed transfusion, and in a reduced outcome. This article presents quickly assessable predictive factors for determining if a blood transfusion is required to improve outcomes in multiple blunt trauma patients admitted to the emergency room. Methods: In a retrospective review of 282 multiple blunt trauma patients who visited our emergency center by emergency rescuer during a 1-year period, possible factors predictive of the need for a blood transfusion were subjected to univariate and multivariate logistic regression analysis. Results: Of blunt trauma patients, 9.2% (26/282), received red blood cells in the first 24 hours of care. Univariate analysis revealed significant associations between blood transfused and heart rate (HR)>100 beats/min, respiratory rate (RR)>20 breaths/min, Glasgow Coma Scale (GCS)<14, Revised Trauma Score (RTS)<11, white blood cell count (WBC)<4000 or >10000, and initial abnormal portable trauma series (C-spine lateral, chest AP, pelvis AP). A multiple regression analysis, with a correction for diagnosis, identified HR>100 beats/min (EXP 3.2), GCS<14 (EXP 4.1), and abnormal trauma series (EXP 2.9), as independent predictors. Conclusion: In our study, systolic blood pressure (SBP)<90 mmHg, old age>65 years, hemoglobin <13g/dL, mechanism of injury were poor predictors of early blood transfusion. Initial abnormal portable trauma series, HR>100 beats/min, and GCS<14 were quickly assessable useful factors for predicting a need for early blood transfusion in blunt trauma patients visiting the emergency room. (J Korean Soc Traumatol 2009;22:218-26)

인공지능 활용에 대한 편익과 우려에 관한 연구

오지선(Jee-Sun Oh),김문구(Moon-Koo Kim),오연수(Yeonsu Oh) 한국통신학회 2022 한국통신학회 학술대회논문집 Vol.2022 No.2

4차 산업혁명의 가장 주요 기술인 인공지능이 인류의 삶을 어떻게 변화시킬 것인지에 대한 예측은 각양각색이다. 세계경제와 산업, 노동시장 등 사회 전반에 다양한 영향을 미치게 될 것이라는 기대와 함께, 인공지능 기술에 의한 편리함이 인간 삶의 영역을 대부분 차지해버릴지 모른다는 우려도 함께 공존한다. 이에 본 연구에서는 인공지능에 대한 일반인 설문조사를 통하여, 일반인들이 인공지능에 대하여 어떤 부분을 기대하고, 어떤 부분을 우려하는지, 그리고 향후 10년 이내에 인공지능을 통해 해결이 필요한 분야는 어떤 분야인지에 도출하였고, 이를 바탕으로 인공지능 연구에 대한 방향과 시사점을 제시하였다. 이를 위해서는 첫째, 사회 불균형 해소와 사회적 약자 보호를 위한 인간중심적 인공지능 개발이 필요하다. 둘째, 인공지능 기술을 악용하지 못하도록 사회적 장치를 마련해야 한다. 역기능 방지 뿐 아니라 편익의 제고를 위해 사회 전체가 데이터를 투명하고 공정하게 상호 운용할 수 있는 안전한 프레임워크가 필요하다. 셋째, 역기능 방지 뿐 아니라 편익의 제고를 위해 사회 전체가 데이터를 투명하고 공정하게 상호 운용할 수 있는 안전한 프레임워크가 필요할 것이다. 마지막으로, 인공지능의 올바른 활용과 투명성, 공정성이 확보되고, 축적된 지식을 공공재화 하여 사회 구성원들에게 투명하게 공개한다면, 인공지능과 공존하는 건강한 미래사회가 구현될 것이다.

필라테스 지도자의 교수행동 분석

오지선 ( Ji Sun Oh ) 한국리듬운동학회 2011 한국리듬운동학회지 Vol.4 No.2

The purpose of this study is to analyze Pilates instructors` teaching behaviors, identify patterns of their teaching behavior variables and characteristics of instructional content composition, and provide basic data for efficient Pilates instruction. For this purpose, 10 female Pilates instructors in charge of a Pilates program for adult females at a ward office, a body type management center, a cultural center, or a private institute in Seoul as of 2005 were selected for data collection; The recorded instructional scenes were measured by the interval-based observation recording method of 5-second observation and 5-second recording. The instructors` behaviors were largely classified by interaction, teaching behavior, and instructional atmosphere variables; then, data processing was carried out through the mean, standard deviation, and percentage of all relevant sub-variables. The results for teaching behaviors can first be summarized as follows: First, as for the mean of occurrence frequency (%) of instructional atmosphere factors, physical activities (A) made up the most part (81.3%), followed by listening learning activities (I) (14.1%), waiting (W) activities (4.20%), and instructional management (M) activities (.3%). Second, as for Pilates instructors` teaching behaviors, joint activities with learners made up the most part (43.7%), followed by physical contact (23.1%) and guiding and lecturing activities (18.7%). On the other hand, correctional technique feedback formed 4.1%, followed instructional management (3.7%), supervising (1.9%), and encouraging activities (1.5%) while positive and negative behavior feedback was on the very low level. Third, as for interaction between a Pilates instructor and a learner, the entire learning interactive activities made up the most part (73.6%), followed by personal interactive activities (26.3%) and group interactive activities (.0%). In conclusion, it is necessary for an instructor to use the time for supervising, lecturing and structuralization of instructional management efficiently through sufficient instructional plans before instruction in consideration of properties of Pilates to allow learners to spend much time in task-based physical activities and to implement learning tasks clearly and accurately by providing the teaching clue of correctional technique feedback.