회원작품: 부산·경남특집 - 화명수목원 전시온실

안성호,공부성,Ahn, Sung-ho,Kong, Boo-seong 대한건축사협회 2014 건축사 Vol.2014 No.1

Synergistic Effects of 5-Fluorouracil (FU) and Curcumin on Human Cervical Cancer Cells

안성호,김동희,강정훈,이명선,Ahn, Seong-Ho,Kim, Dong-Heui,Kang, Jung-Hoon,Lee, Myeong-Seon Korean Society of Microscopy 2010 Applied microscopy Vol.40 No.4

Cervical cancer is associated with low antioxidant status. It has a high prevalence especially amongst woman in Asia and is a leading cause of cancer death. Cancer chemotherapy in vivo improved in cases with high p53 expression in the tumor tissue. The restoration of p53 levels could be a potential strategy to increase chemoresponsiveness. Under circumstances where damage is extensive, p53 plays a direct role in trigering apoptosis. To investigate the effect of curcumin (CMN) as an antioxidant agent on anticancer agent 5-fluorouracil (5FU) induced apoptosis and p53 expression, HPV-18 positive HeLa cells were treated with noncytotoxic amounts of antioxidant. Curcumin induced apoptosis in cervical cancer cells. Morphological hallmarks of apoptosis such as nuclear fragmentation and internucleosomal fragmentation of DNA were observed. CMN caused upregulation of p53 expression, evident from Western blotting data and also increased the susceptibility/apoptosis induced by 5FU. These results show that increasing drug sensitivity of cervical cancer cells by upregulation of p53 using CMN is novel approach and could have a possible therapeutic potential in cervical cancer.

한국의 지방자치체제 개편과 방향

안성호(Ahn, Seong-Ho) 한국지방정부학회 2010 지방정부연구 Vol.14 No.1

본 논문은 시.군.구를 묶어 통합광역시로 만들고, 시.도 자치정부를 폐지하는 대신 국가지방행정기관을 설치하려는 정치권의 개편만을 비판적으로 검토하고, 지방민주주의와 국제경쟁력을 강화하는 대안적 지방자치체제 개편구상을 논의하기 위해 다음과 같은 연구과제들을 다룬다. 첫째, 지방자치구역 및 계층의 현황과 정치권 개편안의 특징을 국제비교의 관점에서 검토한다. 둘째, 정치권 개편안의 문제점을 규모와 효율성.민주주의의 관계를 중심으로 논의한다. 셋째, 정치권의 도 지역정부의 폐지 내지 약화 기도를 국제동향에 비추어 점검한다. 넷째, 정치권 개편안 규모정치의 폭력성과 빗나간 벤치마킹을 비판한다. 끝으로 향후 지방자치구역 및 계층구조를 개편할 때 유념해야 할 이해당사자인 정 치권의 편견 억제와 진문가.시민의 역할 등의 절차적 사항들을 논의한다. This paper aims to critically review the political parties' reorganizing schemes of local self-governing areas/tiers in Korea, and then to discuss the procedural issues to be considered in the process of revising the local self-governing system. To this end, the paper begins with examining the characteristics of both the current status of and the political parties' restructuring schemes on local self-governing areas/tiers from the angle of international comparison. Next, the paper analyzes the serious pitfalls embedded in mainstream political parties' plans: the spurious arguments for efficiency improvement and critical democratic deficits resulting form the radical consolidation of basic-level self-governing units Third, the paper criticizes the political circles' plots to weaken or abolish the 'Do' regional governments in light of international trends of strengthening regional governments. Fourth, the paper examines the secret motives of the political parties to gratify their political interests by redesigning the present local self-governing system to their political tastes. Finally, the paper discusses the procedural issues to be seriously observed in the process of reforming the existing local self-governing system.

행정과 절차적 정의

안성호 ( Seong - Ho Ahn ) 한국행정학회 1991 한국행정학보 Vol.25 No.1

지금까지 행정학도들은 正義의 문제를 주로 결과윤리로서의 分配的 正義에 한정해 논의하는 관행을 굳혀 왔다. 전통적으로 절차에 대해 지대한 관심을 표명해 왔음에도 불구하고, 행정학도들은 절차윤리로서의 節次的 正義에 대해서는 진지한 관심을 기울이지 못해 왔다. 우리는 온전한 행정적 정의론을 정립하기 위하여 분배적 정의론과 더불어 절차적 정의론을 구성해야 한다. 본 논문은 특별히 70년대 중반 이후 활발히 전개되어 온 절차적 정의에 관한 연구의 성과에 힘입어 민주행정에 걸맞는 절차적 정의론의 구성을 시도한다. 먼저, 절차적 정의의 개념적 성격을 밝히고, 민주주의와 절차적 정의의 본질적 관련성을 파악하며, 절차적 정의의 준수를 방해하는 편견들을 검토한다. 다음으로, 경험적 연구결과들로부터 절차적 정의가 정치적 반응 및 평가에 미치는 일관된 영향을 확인한다. 또, 절차요소들에 대한 학자들의 분류들을 일별해 보고, 국민의 입장에서 정부의 정책과정을 도덕적으로 평가하는 경우를 상정하면서 기존의 분류들을 참고하여 민주주의이념에 부합하는 일련의 절차요소목록을 마련한다. 이를테면, 구조적 절차요소로서 참여(발언권, 대표성), 일관성, 교정가능성, 공개성, 편견의 억제, 호소의 기회를, 대인적 절차요소로서 정직성(준법성), 관용의 정신, 이유설명을 제시한다. 끝으로, 절차적 정의의 타락가능성과 한계를 적시한다. 본 논문이 다룬 다양한 내용은 후속 연구들에 의해 이론의 깊이와 넓이를 더해야 하며, 더욱 확고한 경험적 지지를 확보해야 한다.

Classification and Relative Chronology of Dyke Swarms in the Proterozoic Sancheong Anorthositic Rocks, South Korea

안성호(Seong-Ho Ahn),김종선(Jong-Sun Kim),조형성(Hyeongseong Cho),송철우(Cheol-Woo Song),손문(Moon Son),류충렬(Chung-Ryul Ryoo),김인수(In-Soo Kim) 대한지질학회 2010 지질학회지 Vol.46 No.1

구조중심 협동학습 활용 생물과 환경 단원 수업이 초등학생의 과학적 의사소통 능력에 미치는 영향

안성호 ( Seong Ho Ahn ),신영준 ( Young Joon Shin ) 한국생물교육학회 2015 생물교육 Vol.43 No.4

‘The purpose of this study was to investigate effects of structure-centered cooperative learning which improves the scientific communication skills in elementary school. To examine effects of structured cooperative learning, two six-grade classes from the same elementary school in Gyeonggi province were respectively selected as the experimental and control group. The experimental group was taught using structure-centered cooperative learning, while the control group was taught using traditional explanation. The major findings are as follows; First, the students who were taught using structure-centered cooperative learning program had high scores in the describing area of the scientific explanations than those in the control group. Second, structurecentered cooperative learning program suggests that statistically significant results in justified claim area of the scientific claims. But, there is no significant differences in explaining and evidence-based claim area between two groups.

엔드밀링 가공에서 절삭력 계수 데이터베이스 구현을 위한 일반화된 방법론

안성호(Seong Ho Ahn),고정훈(Jeong Hoon Ko),조동우(Dong-Woo Cho) Korean Society for Precision Engineering 2003 한국정밀공학회지 Vol.20 No.8

지방분권화정책의 변동과 향후 개혁과제 - 정부간 기능재분배 개혁을 중심으로 -

안성호(Seong Ho Ahn) 한국지방자치학회 1999 한국지방자치학회보 Vol.11 No.4

In order to explore the reform agenda of the future decentralization policy in Korea, the paper deals with some relevant research tasks as follows. Firstly, it examines the decentralization policy shifts in the 1990s in terms of the aggergate change of the intergovernmental redistribution of functions. Secondly, it analyzes the recently-revised intergovernmental redistribution procedure of functions and characterizes the Intergovernmental Devolution Promotion Law enacted in December 1998 in comparison with the Japanese corresponding law, i.e., Decentralization Promotion Law and its implementation experience. Thirdly, on the basis of the previous discussion are some major reform agenda guiding the future decentralization policy suggested.

행정과 정의 - 행정에 있어서 정의연구의 몇가지 의제 -

안성호 ( Seong - Ho Ahn ) 한국행정학회 1989 韓國行政學報 Vol.23 No.2

광역시와 자치구의 정부관련계 분석 - 대전광역시의 사례 -

안성호 ( Seong Ho Ahn ) 한국지방자치학회 1997 한국지방자치학회보 Vol.9 No.3

This paper is divided into two main parts: the first part analyzes the actual conditions of the intergovernmental relationships between the metropolitan city and the self-governing districts in Daejon metropolis; and the second part suggests some recommendations for the future desirable intergovernmental relationships between the metropolitan city and the self-governing districts. The firs part begins with the investigation into the functional allocation status quo, financial relations, conflict cases, and public servants` perceptions about the various aspects of relations between the metropolitan city and the self-governing districts in Daejon metropolis. The above analysis of these realities leads to some reform recommendations in the second part. They comprise maintaining the current two-tier governmental system and strengthening the autonomy rights of both the metropolitan city and the self-governing districts in the context of the existing hyper-centralized intergovermmental relationships` reallocating the governmental functions between the metropolitan city and the self-governing districts based on the principle of functional specialization; guaranteeing the maxiumum effctive participation of both the metropolitan city and the self-governing the maximum effective participation of both the metropolitan city and the self-governing districts in the decision-making process concerning the reallocation of governmental function; recompensing fully the accrued expenses corresponding to the intergovernmental delegation and devolution of function`; and creating a `Metropolitan City/Self-Governing Distrcts Administrative Committee` that will operate on a regular and institutionalized basis for effective policy adjustment and conflict-resolution.