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주관적 기억감퇴를 가진 노인에서 백질 변화와 인지기능 장애의 관련성
신은영,정한용,김양래,이소영,김신겸,Shin, Eun-Young,Jung, Han-Yong,Kim, Yang-Rae,Lee, So-Young-Irene,Kim, Shin-Gyeom 대한생물정신의학회 2011 생물정신의학 Vol.18 No.3
Objectives The purpose of this study is to evaluate the relationship between the severity of white matter changes (WMC), risk factors and cognitive domains, including executive function profiles. Method Forty nine subjects over 55 years with subjective memory complaints were assessed with MRI and neuropsychological tests. The WMC were assessed by MRI T2-FLAIR images and divided into 3 groups of mild vs. moderate vs. severe and 2 groups of mild-moderate vs. severe by using Mantyla's criteria and Fazeka's criteria. The risk factors were examined in hypertension, heart disease history and chemistry Lab. Medical conditions which affect to cognitive dysfunction and definite dementia were also excluded. Results Comparing 3 groups, hypertension was identified as a risk factor of the WMC. Comparing 2 groups, total cholesterol and LDL were identified for as the risk factor of WMC. The severity of WMC was significantly associated with cognitive disturbances and their main effect on cognition was working memory and inhibition. Conclusion The risk factors of the WMC in the elderly were hypertension, hyperlipidemia. The severity of WMC appears to be associated with executive dysfunction in the elderly.
그린캠퍼스를 위한 국내.외 대학시설관리(FM) 비교분석 - 에너지관리 중심 -
신은영,김준하,Shin, Eun-Young,Kim, Jun-Ha 한국교육시설학회 2012 교육시설 Vol.19 No.1
Recently, as the environment issue has been stand out, people's interests in energy consumption of the building have been increased as well. Especially, university has been classified as the one of the main causes of excessive energy consumption. Therefore, domestic and foreign universities are trying to build a green campus in an attempt for sustainable development. Since early 2000s, foreign universities have been aware that one of the main causes of global warming is an excessive consumption of energy in universities. Accordingly, they adopted various energy management programs for the conservation. Ultimately, enforcing energy conservation and using alternative energy resulted in lower expense and it was a great help for the universities. On the other hand, excessive consumption of energy in domestic universities has been considered as serious, which led them to become the second main energy consumers in 2010. However, it seems people do not truly recognize the impotance of energy management, therefore, relatively little attention has been paid to this matter. Based on Leadership in Energy & Environmental Design(LEED) rating systems for on-campus building operation and maintenance, this research suggests the evaluation standard to effectively analyze the energy management activity with the best practices conducted in foreign universities and to solve the problem of campus facilities management in domestic universities. The result shows that domestic universities do not have a designated task force for effective energy management and the lack of energy professionals hinders for the long term development. Therefore, domestic universities should recognize the seriousness of the excessive energy consumption and develop low carbon green campus through proactive management practices since this is very essential for domestic universities to get more competitive in this global era.
신은영,박환표,Shin, Eun-Young,Park, Hwan-Pyo 한국건설관리학회 2006 건설관리 : 한국건설관리학회 학회지 Vol.7 No.2
The cost of construction engineering field is less than $3{\sim}5%$ of the gross construction cost, it, however, is very important because the performance of final facility depends on the technical ability of construction engineering company. However, as the results of the technical level of domestic construction engineering survey from experts, it was less than 70% of developed country. For this reason, domestic construction engineering companies are confronted with serious problems to go into overseas market. Accordingly, this research analyzed the construction engineering market trend of domestic and overseas in order to suggest the strategies to go into the Vietnam. Moreover, this research identified problems and strategies of making inroads into the world market through the survey from the domestic construction company related to overseas construction, advanced a theory through extensive literature review, and collected extensive opinions through an interview with domestic and foreign experts and business trip. The purpose of this research is to provide market analysis and strategic plan for advancing into overseas market in order to make the domestic construction engineering companies to go into the Vietnam market. Especially, as a plan for the revitalization of advancing overseas market of domestic construction engineering companies, this research proposed Constructing Local Infrastructure, Business Creation of Planning Proposals and Enlarged Plans of ODA(Official Development Assistant).
성학대를 경험한 소아, 청소년에서 성학대가 외상 후 정신 증상에 미치는 영향
신은영(Eun-Young Shin),천근아(Keun-Ah Cheon),정경운(Kyungun Jhung),송동호(Dong-Ho Song),김소향(So-Hyang Kim) 대한소아청소년정신의학회 2015 소아청소년정신의학 Vol.26 No.1
Objectives:The purpose of this study is to examine the effects of the characteristics of victim and sexual abuse on posttraumatic psychiatric symptoms in children and adolescents with a history of sexual abuse. Methods:A total of 137 children and adolescents were recruited from the Seoul Sunflower Children Center, a nation-funded sexual violence victim protection center, from January 2009 to December 2013. We collected the demographic data of the victims and the Trauma Symptom Checklist for Children (TSCC) from victims. We hypothesized victims’ age, sex, and intelligence quotient, and the characteristics of sexual abuse as the affecting factors of posttraumatic psychiatric symptoms. Descriptive analysis and hierarchical regression analysis were performed for analysis of demographic data, TSCC scores, and psychiatric symptoms. Results:The victims’ age and the characteristics of sexual abuse were significantly related to the traumatic distress of sexual abuse. R-square was 23% for anxiety, 39% for depression, 21% for posttraumatic stress, and 37% for dissociation on TSCC. Conclusion:This study suggests that victims’ age, type, frequency and duration of exposure, and disclosure of sexual abuse are significant affecting factors on posttraumatic psychiatric symptoms in children and adolescents. Exploration of psychiatric symptoms other than posttraumatic symptoms, and relations between pretraumatic and posttraumatic psychiatric symptoms is needed through collection of larger samples.
신은영 ( Eun Young Shin ),이정민 ( Jeoung Min Lee ) 한국미용학회 2010 한국미용학회지 Vol.16 No.2
Artificial nails should be removed from the natural ones after a certain period of time. It is during the removal process that the natural nails, which once had artificial ones attached to them, go through physical and chemical changes. Under the goal of investigating nail damage according to removal methods, this study compared two types of nails of the same company in the domestic nail market for changes to the nail shape and nail damage according to removal methods. The products were gel nails that could be removed through filing and the ones through a special solution or acetone. A group of women, who showed no special problems with their health, maintained a relatively good state of health, and were 25 or 28, was convenience sampled. Total six subjects were chosen who included three that were 25 and another three were 28. Both the age groups received no nail treatment for the last two months. The subjects were given a number from A to F. Before the experiment, their nails were measured in thickness. The middle finger thickness that was the closest to the mean was chosen as the experiment sample. Before treating the gel nails, the free edge of the nail was cut by 2 mm to measure its condition. Since there is no widely accepted method to measure nail damage, the investigator made the natural nails before attaching artificial ones the control group and did four treatments of artificial nails on the same nails every two weeks for eight weeks. The experiment group included the gathered sample nails. A multilateral experimental analysis was carried out in shape changes, strength, and thickness to understand the influences on the structural changes of the natural nails.
이종이식 PEOH 세포주에서 clusterin에 대한 shRNA의 paclitaxel 내성 효과
신은영 ( Eun Young Shin ),정인철 ( In Cheal Jeung ),최주혁 ( Joo Hyuk Choi ),박동춘 ( Dong Choon Park ) 대한산부인과학회 2007 Obstetrics & Gynecology Science Vol.50 No.11
Objective: To evaluate the inhibition of Clusterin gene expression via shRNA decreases proliferation and metastasis and increases chemo-sensitivity to paclitaxel in xenografted PEOH cells. Methods: 1×106 paclitaxel resistant cell lines transduced with Clusterin shRNA in lentiviral inoculated subcutaneously into the flank region of 6 to 8 week-old female nude mice. Parental cells transduced with LacZ was used as a control. Tumor growth was measured twice every week and calculated by using the formula: length×width×depth×0.5236. The mice were sacrificed and examined for Clusterin expression on tumor cells and counted the metastasis sites. Results: shRNA for Cluaterin works in vivo and it is the in accord with the in vitro results. Although shRNA for Clusterin group showed decreased tumor growth and proliferation it has not statistical significance. But transfection of Clusterin shRNA on PEOH significantly increased paclitaxel-sensitivity (P<0.05). Conclusion: shRNA targeting of the Clusterin gene decreased the ovarian cancer cell`s paclitaxel resistance.
신은영 ( Eun Young Shin ) 한국불어불문학회 2014 불어불문학연구 Vol.0 No.99
Selon J. Morel, les ``ridicules`` molieresques definissent negativement un type d``homme : ``l``honnete homme`` qui est raisonnable, s``efforce au naturel et ne se pique de rien. Dans le theatre de Moliere, il est souvent represente par le ``raisonneur``. Or l``idee d``honnetete se trouve au coeur de son oeuvre, aussi bien dans l``homme que dans la femme. Ce que nous allons examiner dans cet article, ce sont les aspects de cette ``honnete femme``. Au XVIIe siecle, l``ideal de l``honnetete s``est defini parallelement pour l``homme et pour la femme : ils possedent l``art de plaire qui consiste a s``accommoder a l``esprit des autres. L``honnetete est faite de moderation et de mesure ; elle s``oppose avant tout a l``affectation. Ils doivent etre naturels(c``est-a-dire accord entre etre et paraitre) et raisonnables(c``est-a-dire pouvoir de discerner le masque et le visage). Mais, si les deux modeles sont semblables, la difference des sexes se marque dans certains conditionnements. Meme si l``honnete femme, munie de certaine culture non scolastique, se trouve au centre de la vie mondaine, ses aspirations doivent se contenir dans le role propre de la femme defini par la morale chretienne. Cette tendance va se renforcer dans la deuxieme moitie du XVIIe siecle. Dans le theatre de Moliere, les aspects de l``honnete femme sont d``abord dessines en creux par les ``ridicules``, dont le defaut se converge a l``affectation. Ce sont les precieuses(affectation de classe sociale), les prudes(affectation de vertu), les coquettes(affectation de sentiment) et les femmes savantes (affectation de savoir). Parmi les personnages feminins de Moliere, on trouve rarement une honnete femme typique, comparable au ``raisonneur``, sauf Eliante dans le Misanthrope. Pourtant plusieurs personnages possedent certaines qualites de l``honnete femme : Agnes ``naturelle`` dans l``Ecole des femmes, Uranie ``raisonnable``, dans la Critique de l``Ecole des femmes, qui jouit de la vie de societe, Elmire, dans Le Tartuffe, qui represente l``honnete femme ideale dans la famille. Quant a Eliante, elle montre plus de discretion et de clarte que son double masculin Philinte dans la mesure ou elle garde un juste milieu entre l``ideal de la sincerite et la complaisance. L``idee d``honnetete se trouve au centre du theatre de Moliere dans la mesure ou l``art de plaire est la fin communement poursuivie par l``honnete homme et par la comedie: ce que Moliere essaie de faire, c``est de faire rire les honnetes gens. L``interpenetration s``opere donc entre l``art d``ecrire et l``art de vivre, entre l``esthetique et la morale: les honnetes gens doivent ``jouer``, ainsi que les acteurs, pour plaire a leur public. Or cet ideal d``honnetete se change dans la deuxieme moitie du XVIIe siecle ou les honnetes gens deviennent des ``hypocrites`` dans la mesure ou ils se masquent uniquement pour plaire, tout en reconnaissant la faussete de cet art de vivre. C``est le commencement d``un nouvel ideal d``homme de bien qui va remplacer celui d``honnete homme. Eliante, cette honnete femme dans le Misanthrope, qui estime la sincerite d``Alceste, annonce ainsi ce changement qui va s``accomplir au XVIIIe siecle.