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손동석,김윤범,Son, Dong-Seok,Kim, Yoon-Bum 대한한방안이비인후피부과학회 2002 한방안이비인후피부과학회지 Vol.15 No.2
Objective : The aim of this study was to investigate the skin-whitening effect of Kakamseosiokyong-san Method : We investigated that the extracts of Kakamseosiokyong-san inhibit activity of tyrosinase, the enzyme which converts 3-(3,4-dihydroxyphenyl)alanine to dopachrom in the biosynthetic process of melanin. the UV absorbance of the extracts in the UV - A region and UV - B region was measured by UV scanning. the effect of extracts on cell viability and melanin production in cultured B16 mouse melanoma cells was measured, and cytoprotective effects of extracts on PC12 cells injured by hydrogen peroxide was measured by MTT assay Results: The extracts of Kakamseosiokyong-san inhibited activity of tyrosinase. The extracts not only showed inhibitory effects on melanin production in cultured B16 mouse melanoma cells, but also exhibited cytoprotective effects on PC12 cells injured by hydrogen peroxide, but did not showed an absorbance in the UV - A region and UV - B region. Conclusion: These results suggest that Kakamseosiokyong-san inhibit melanin biosynthesis which is involved in hyperpigmentation and could be used as a whitening agent for the skin.
Histomorphometric study of rabbit’s maxillary sinus augmentation with various graft materials
손동석,문용석 대한해부학회 2018 Anatomy & Cell Biology Vol.51 No.S1
The purpose of this animal study is to evaluate, by histomorphometric analysis, bone regeneration in rabbit’s maxillary sinuses with blood clots alone, Bio-Oss, β-tricalcium phosphate (β-TCP), and demineralized tooth dentin (DTD) grafting. Bilateral sinus augmentation procedures were performed in 18 adult male rabbits. Rectangular replaceable bony windows were made with a piezoelectric thin saw insert. In the group 1, blood clots were filled; group 2, anorganic bovine graft (Bio-Oss) was grafted; group 3, β-TCP was grafted; group 4, DTD was grafted, and covered by replaceable bony windows. Animals were sacrificed at 2, 4, and 8 weeks after surgical procedure. The augmented sinuses were evaluated by histomorphometric analysis using hematoxylin and eosin and Masson’s trichrome stains. Histologically, new bone formation was revealed along the elevated sinus membrane and all graft materials. The new bone area of the group 2 was significantly greater than the group 1, and of the group 3 was significantly greater than the group 2, and of the group 4 was significantly greater than the group 3 at 8 weeks with P<0.05. The bone marrow area of group 1 was significantly greater than other groups at 8 weeks. The DTD area was significantly lesser than Bio-Oss or β-TCP particles area at 8 weeks. This present study suggests that DTD can be effective graft materials for bone regeneration of the maxillary sinus augmentation.
성인에서 두개안면골의 성장과 변화 : 24세에서 31세까지
손동석 慶北大學校 齒科大學 1996 慶北齒大論文集 Vol.13 No.-
한국인 성인의 두개안면부의 성장 변화를 관찰하기 위하여 평균 연령 24세의 성인 남자 25명과 여자 15명의 두부 X선 규격사진을 활영한 후 7년 후에 추적하여 다시 촬영한 연속 두부 X선 규격 사진을 분석하여 다음과 같은 결론을 얻었다. 1) 여자에서 하악골은 시계방향으로 회전하였고 하악골의 길이는 변화가 없었다. 남자에서는 하악골에서 변화가 없었다. 2) 남녀 모두에서 교합평면에서 변화가 없었다. 3) 치축의 변화에서는 여자의 상악절치에서 약간의 설측경사가 있었다. 4) 두개저는 남녀 모두에서 본 연구기간 동안 변화가 없었다. 5) 남녀 모두에서 lower anterior facial height, upper facial height & lower facial height 에서 경미한 증가가 나타났다. 6) overbite, overjet, ODI, & APDI는 남녀 모두에서 유의성 있는 변화가 없었다. 7) 개인적인 성장 변화도를 관찰시 남자에서 1명이 뚜렷한 하악골의 성장을 보였고 다른 1명에서 하악골의 후방회전을 보였다. 여자에서는 2명이 뚜렷한 하악골의 성장을 보였고 다른 1명에서 하악골의 뚜렷한 후방회전을 보였다. The purpose of this study was the describe craniofacial changes of Korean adults aged from 24 to 31 year. The Serial cephalograms of 40 samples(25 males & 15 males) was taken at the age of 24 and 31 years in this study. The following results were obtained: 1) Mandible was rotated to clockwise direction in female. But there was no changesof mandible in male. 2) There was no changes of occlusal plane in both sexes. 3) Upper incisors moved lingually(linguoversion) in female. 4) There was no growth changes of cranial base in both sexes. 5) Lower anterior facial height, upper facial height and lower facial height was increased slightly in both sexes. 6) There was no significant changes of overbite, overjet, ODI and APDI in both sexes. 6) There was no significant changes of overbite, overjet, ODI and APDI in both sexes. 7) Individually, one male and two females showed prominent mandibular growth. One male and one female showed prominent backward rotation of mandible.
손동석(Dong-Seok Sohn),이지수(Ji-soo Lee),안미라(Mi-ra Ahn),신홍인(Hong-In Shin) 대한치과의사협회 2008 대한치과의사협회지 Vol.46 No.4
Various maxillary sinus floor augmentation techniques were common performed and in the most cases, many kinds of bone graft materials were used. The graft materials are autogenous bone or other biomaterials of human, artimal or synthetic origin. but these cases, report describes a new surgical technique by which dental implants are inserted in a void space created by elevating the sinus membrane without additional graft material in atrophic posterior maxilla. We created lateral bony window using piezoelectric device and elevated the schneiderian membrane in ten patients. Dental implants were simultancously placed and lateral window prepared was covered with non-resorbable membrane in five patients and was repositioned with bony window in five patients, without any bone graft. From the clinical and histological results, it is found there is potential capacity for bone formation and placement of implants in the maxillary sinus without the use of bone grafts or bone substitutes.
손동석,배성민 대구효성가톨릭대학교 1998 연구논문집 Vol.57 No.2
This is a case report of ameloblastoma in left mandible. A 30 years old woman patient visited our department for evaluation of swelling and pain of left mandible. She was diagnosed plexiform ameloblastoma according to clinical and radiological examinations and biopsy. In order to preserve function and esthetics of her mandible, we treated her by enucleation curettage and obturator. There is no evidence of recurrence 2 years after operation.