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Peutz - Jeghers Syndrome 의 2 예
변동길,남용진,설수길 대한피부과학회 1965 大韓皮膚科學會誌 Vol.4 No.1
Two cases of Feutz-Jeghers Syndrome which showed typical muco-cutaneous pigmentations were reported and the literatures were reviewed. The case 1 was 9 years old boy, who began to have his skin pigmentations 8 years ago but had no gastro-intestinal symptoms No gastro-intestinal polyposis was demonstrable by X-ray r.xamination, but a fetus head sized space was noted in the pelvic area which pressed the small bowel upward. The case 2 was 10 years old girl, who also began to have her skin lesions 8 years ago and had periodic epigactric pain at the intervals of 10 to 14 days for I year which was suggestive of the possibility of the intestinal polyposis But the patient refused X-ray study against medical advice.
Finite Element Analysis of the Biomechanical Effect of Coflex™ on the Lumbar Spine
변동학,신동아,김진명,김소희,김형일 대한척추신경외과학회 2012 Neurospine Vol.9 No.3
Objective: The biomechanical properties of the Coflex™ (Paradigm Spine, NY, USA), a device designed to provide dynamic stabilization without lumbar fusion, have not been clearly defined. The purpose of this study was to determine the efficacy and biomechanical effect of Coflex™ using finite element model (FEM). Methods: A 3D geometric model of the L3-L5 was created by integrating computerized tomography (CT) images. Based on the geometric model, a 3D FEM was created and the Coflex™ model was incorporated into the base model. Mechanical load dependent on the postural changes and boundary conditions, were imposed to simulate various 3D physiological states. The simulation analysis included stress and strain distributions, intervertebral disc deformation, and the range of motion of the facet joint and lumbar spinous process. Results: Coflex™ significantly restrained displacement in extension, lateral bending and compression of joint between the L4-5 as one in the experimental group was observed -1.3% of flexion, -24.5% of extension, -44.5% of lateral bending and -37.2%. The average intradiscal pressure of the L4-5 decreased by 63% and the average facet contract force of the L4-5decreased markedly by 34% in the experimental group. A load of 120 MPa from extension was observed at the base of spinous process in the experimental group. Conclusion: The Coflex™ can be safely used for achieving functional dynamic stabilization of the lumbar vertebral column while preserving the intactness of the other components. However, the fatigue fracture of the L4 spinous process should be carefully monitored.