A Case of Vanishing Bile Duct Syndrome after Drug-Induced Liver Injury Caused by Pelubiprofen

박해인,김하연,이시은,이윤석,방수민,이영선 연세대학교의과대학 2020 Yonsei medical journal Vol.61 No.12

Vanishing bile duct syndrome (VBDS) is a rare disease characterized by ductopenia and cholestasis, and is linked to immunologicaldamage to the bile duct system. VBDS can be triggered by infection, ischemia, autoimmune diseases, adverse drug reactions,and humoral factors associated with malignancy. A few cases of VBDS associated with nonsteroidal anti-inflammatory drug-relateddrug-induced liver injury (DILI) have been reported. Here, we report a case of a 29-year-old patient who developed DILI thatprogressed to VBDS after the administration of pelubiprofen.

견비통의 변증에 관한 문헌고찰

박해인,이광호 대한침구의학회 2015 대한침구의학회지 Vol.32 No.2

Objectives : The aim of this study is to summarise pattern-identification of shoulder pain based on the classics of oriental medicine, current literature and domestic papers. Methods : The materials selected were sourced from the classics of oriental medicine, current literature and domestic papers which contained data related to pattern-identification of shoulder pain. The pattern-identifications were compared to determine the similarities, and these were classified. Results : Thirty-five studies were reviewed, and thirty-seven pattern-identifications were collated. These were classified into the following groups: wind-cold-dampness group(n = 8), blood stasis group(n = 3), phlegm group(n = 7), dual deficiency of Qi and blood group(n = 4), deficiency cold group(n = 2), liver-kidney deficiency group(n = 1) and meridian-collateral group(n = 12). Conclusions : On the basis of the classification of pattern-identifications, two groups of pattern-identifications for shoulder pain were suggested. The first group included the pattern-identification associated with a disease-cause, which included the wind-cold- dampness pattern(風寒濕型), blood stasis pattern(瘀血型), phlegm pattern(痰飮型), Qi-blood deficiency pattern(氣血兩虛型), deficiency cold pattern(虛寒型), and liver-kidney deficiency pattern(肝腎虧損型). The second included the pattern-identification associated with the meridian-collateral, which included the hand greater Yin meridian pattern(手太陰經型), hand Yang brightness meridian pattern(手陽明經型), hand lesser Yin meridian pattern(手少陰經型), hand greater Yang meridian pattern(手太陽經型), hand reverting Yin meridian pattern(手厥陰經型), hand lesser Yang meridian pattern(手少陽經型), and foot greater Yang meridian pattern(足太陽經型).

Cultural Differences in Event Construal: Evidence from Monolingual and Bilingual Speakers

박해인 한국응용언어학회 2017 응용 언어학 Vol.33 No.3

According to cross-cultural psychology research, East Asians and Westerners perceive and evaluate the world in different ways. While East Asians are inclined to follow a broad perceptual or conceptual field and to be concerned with relationships between objects, Westerners are more likely to concentrate on a focal object and its properties. Ample evidence is now available that shows that these cross-cultural differences may yield differences in cognitive processes (Nisbett, 2010; Nisbett & Miyamoto, 2005). However, research into cultural influences on cognition to date has largely focused on examining monolingual speakers, and less is known about how cross-cultural influences affect bilingual cognition. Therefore, in the present study, an attempt was made to examine how Korean-English bilinguals, sampled at varying levels (n = 80), interpreted event scenes in comparison to Korean and English monolinguals (n = 15 each). Participants were asked to describe four event scenes, which could afford multiple perceptual interpretations. The event descriptions by the Korean and English monolinguals revealed typical East Asian and Western cognitive styles, respectively, to interpret and describe event scenes. Furthermore, the pattern of the event construal of the bilinguals did not completely match that of either monolingual group, suggesting that they have been influenced by both East Asian and Western modes of thought when interpreting and describing event scenes.

Computed Tomography를 통한 천추(ST25)의 자침 깊이에 대한 후향적 연구

박해인,양현정,박상균,이광호 대한침구의학회 2015 대한침구의학회지 Vol.32 No.3

Objectives : The aim of this study is to investigate the safe needling depth of Cheonchu(ST25) retrospectively by using an abdomen abdomen computed tomography(CT), and to analyze the correlation between needling depth and the characteristics of the subjects. Methods : We marked spots 50 mm away from both sides of the umbilicus in the abdomen CT and measured the vertical distance to the parietal peritoneum from the skin surface as well as waist circumference. Correlations between measured depth of Cheonchu(ST25) and variables such as age, gender and waist circumference were analyzed. Results : Average depth of the Cheonchu(n = 90) was 3.21±0.87 cm, the minimum was 1.31 cm and the maximum was 5.63 cm. A definite positive correlation was noted between needling depth and waist circumference and a significant difference was observed in needling depth according to waist circumference groups. Conclusions : Needling depth of Cheonchu(ST25) varied depending on the patient’s waist circumference; safe needling depth of Cheonchu(ST25) measured by abdomen CT is 1.31~5.63 cm.

절개침 치료를 이용한 안면주름 개선 8례

박해인,양현정,임청산,조승필,박상균,이광호 대한침구의학회 2014 대한침구의학회지 Vol.31 No.2

Objectives : The purpose of this study was to examine and report improvements of facial wrinkles with the use of subcision. Methods : Subcision acupuncture was performed on outpatients with facial wrinkles for one to two times. Evaluation of improvement was conducted with patient-report questionnaires and comparison of before and after pictures. Items for satisfaction and adverse events were included in the questionnaire, and it was filled out after treatment. The photographs were taken three times; before the first and the second subcision acupuncture, and two to four weeks after the second subcision acupuncture. Results : The results from questionnaire and photo comparison were reported positive and satisfactory. There were minor adverse events such as bruise or conspicuousness of other wrinkles that were not treated. Conclusions : Our study results suggests that the use of subcision acupuncture is effective for facial wrinkles

선천 안진을 동반한 터너증후군

박해인,이상원,오단아,윤혜원 대한신경과학회 2018 대한신경과학회지 Vol.36 No.1

Effect of Oral Contraceptives on Rheumatoid Arthritis in Korean Menopausal Women: A Nationwide Study

박해인,정한샘,홍순준,송관규,정재현 대한내과학회 2017 대한내과학회 추계학술대회 Vol.2017 No.1

한국형 심리적 응급처치 교육프로그램을 이용한 재난정신건강 지원 인력 양성 교육의 효과

박해인,최선우,최윤경,박수현,유성은,백명재,김희국,현진희,석정호 대한신경정신의학회 2020 신경정신의학 Vol.59 No.2

Objectives This study aimed to develop a Korean version of psychological first aid training program (K-PFA) and examine the education effect on trainees. Methods This study enrolled 485 subjects who completed both K-PFA and study surveys. In addition to mental health professionals, subjects with various ages and educational backgrounds were included to examine the education effects of the capabilities in conducting PFA and understanding acute phase disaster mental health (DMH). Results Both mental health professionals and non-professionals improved their understanding of acute-phase DMH intervention and their perceived capabilities in conducting PFA. Conclusion The development of a DMH intervention-training program adapted to Korean domestic circumstances and culture represents a significant step towards a comprehensive and individualized intervention for disaster survivors.

How do speakers of different languages differ in the encoding of complex motion events?

박해인 경희대학교 언어정보연구소 2020 언어연구 Vol.37 No.1

Languages vary considerably in how they encode motion. Research (Slobin 2004; Talmy 1985, 2000) has shown that inter-typological differences are found in the frequency of encoding (high vs. low) as well as in the locus of encoding (main verb vs. satellite). Based on these typological differences, cross-linguistic influence (CLI) research has sought to examine the impact of language typology on the processes and outcomes of second language (L2) learning. While research in this area has been fruitful in the past decade, the majority of studies (Cadierno and Ruiz 2006; Daller, Treffers-Daller, and Furman 2011; Park 2019) have centered on investigating the encoding of path and manner of spontaneous motion events. To expand our understanding of how different components of a motion event get selected and sequenced for verbalization, the current study compared encoding patterns of complex motion events by three different language groups (Korean speakers, n=15, English speakers, n=15, Korean learners of English, n=80). Complex motion events comprised three components of motion (i.e., path, manner, and cause), and participants’ descriptions were elicited using a video description task. The results indicated that monolingual speakers exhibited both universal and language-specific encoding patterns, and that English as a Foreign Language (EFL) learners’ motion event descriptions in the L2 displayed L1-based patterns as well as unique characteristics that are specific to EFL learners. In addition, EFL learners’ English-like encoding patterns of complex motion events were largely predicted by L2 productive vocabulary scores.

어른

朴海璿(박해선) 관훈클럽 2004 관훈저널 Vol.45 No.2