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      • KCI등재후보

        급성 심부전의 혈역학적 감시와 치료

        박철수 대한중환자의학회 2011 Acute and Critical Care Vol.26 No.1

        Acute heart failure (AHF) has emerged as a major public health problem over the past 2 decades and AHF represents a period of high risk for patients, during which time the patients are more susceptible to have fatal outcomes or be re-hospitalized, compared to periods of chronic stable heart failure. The goals of AHF treatment are symptomatic relief and hemodynamic stabilization, which need accurate assessment of volume status and cardiac function of patients. Until now, there is a paucity of controlled clinical data to define optimal treatment for patients with AHF and most guidelines published by the American Heart Association or European Society of Cardiology have been generated by the consensus opinions of experts. In these guidelines, routine invasive hemodynamic monitoring of AHF patients is not recommended because there have not been any reports showing survival benefit in patients monitored with pulmonary artery catheters. At present, treatment strategies based on clinical characteristics such as pulmonary congestion and tissue hypoperfusion rather than invasive hemodynamic monitoring is widely accepted. In this article, we discuss an optimal management plan including appropriate assessment of the hemodynamic status of patients and treatment of AHF.

      • KCI등재

        천해 음파전달 모의에 적합한 음선기반 광대역 신호 모델링 기법에 관한 연구

        박철수,조용진,안종우,성우제,Park Cheol-Soo,Cho Yong-Jin,Ahn Jong-Woo,Seong Woo-Jae 한국음향학회 2006 韓國音響學會誌 Vol.25 No.6

        본 논문에서는 천해 음파전달 모의에 적합한 음선기반 광대역 주파수 신호 모의기법을 제안하였다. 본 기법은 깊이에 따라 음속이 선형적으로 변하는 환경 및 층매질에서의 음선추적을 기반으로 평면파 및 구형파의 반사 및 투과, 굴절 그리고 감쇠 등을 고려해 각 고유음선의 위상 및 크기로부터 신호를 모의한다. 본 기법의 가장 큰 특징은 주파수영역을 거치지 않고 시간영역에서 이산화된 신호를 직접 모의함으로써 주파수 대역에 관계없이 계산시간을 단축할 수 있다는 것이다. 끝으로 제안된 기법을 네 가지의 테스트환경에 적용하여 기존의 검증된 모텔 (ORCA, Ram) 의 결과와 비교하여 그 효용성을 검증하였다 This paper proposes a ray-based forward modeling scheme which is suitable for the shallow water acoustic wave propagation simulations. The proposed model comprises of ray tracings for the layered media of which sound speed profiles are interpolated linearly. considerations of plane and spherical wave reflection coefficients. and calculations of the phases and the amplitudes of eigen rays. The main characteristic of the scheme is fast simulation time due to direct calculation of the broad-band time signals in the time-domain, i.e. without transformation of the frequency-domain solutions to the time si 밍 131s. Finally, we applied the model to 4-types of test environments and compared the resulting signals with those of ORCA and Ram in order to validate the proposed model.

      • KCI등재

        광범위자궁적출술 환자에서 출혈에 의한 혈액 희석 후혈전탄성묘사도의 변화

        박철수,이재민,김용석 대한마취통증의학회 2005 Korean Journal of Anesthesiology Vol.49 No.1

        Background: Recent studies have produced conflicting results on the influence of hemodilution on the coagulation system. Furthermore, only a few clinical studies have been conducted regarding actual blood loss and associated hemodilution. The purpose of this study was to investigate changes in thromboelastograph (TEG) findings after moderate bleeding-induced hemodilution in patients undergoing radical hysterectomy. Methods: 23 patients scheduled for radical hysterectomy were included. No patient had a preoperative coagulation abnormality or was receiving anticoagulant or antiplatelet medication. TEG findings 15 min after induction of anesthesia and after an estimated blood loss equaling 15% of the estimated blood volume were compared. Only crystalloid solution was administered until the second blood sampling for TEG analysis in order to produce a hemodilution state. Results: After hemodilution R time, K time and coagulation time (r + k) showed significant reductions, and alpha angle and TEG index showed significant increases (P < 0.01), and increased coagulability. MA increased after hemodilution, but this was not statistically significant. A60 and CL60 also increased, showing decreased fibrinolysis (P < 0.05). Conclusions: Moderate bleeding-induced hemodilution increased coagulability according to TEG compared to pre-hemodilution findings. We recommend that the decision to replace coagulation factors and/or platelets should not be based on empirically derived, arbitrary standards.

      • KCI등재

        간 이식시 저용량의 아프로티닌이 재관류 후 섬유소용해에 미치는 영향

        박철수,최종호,김은성,김승용 대한마취통증의학회 2005 Korean Journal of Anesthesiology Vol.49 No.5

        Background: The patients with end-staged liver failure are subjected to various and complex coagulopathies during liver transplantation. Particularly, fibrinolysis can occur preoperatively and is more prominent and aggravated right after reperfusion to the donated liver. It becomes the main cause of bleeding intraoperatively and postoperatively. We examined the effect of low dose aprotinin on the fibrinolysis and the transfusion amount of the packed red cell during operation. Methods: We divided the patients into an experimental group, administrating aprotinin (n = 20) and a control group, administrating same volume of normal saline (n = 28). Heparinase-guided thromboelastograph (h-TEG) of preanhepatic 60 minutes was done as basic value. Then we administrated 1 million KIU aprotinin for 20 minutes and infused 0.25 million KIU /hr aprotinin for 3 hours of preanhepatic period in the experimental group. Just after the reperfusion to donated liver, another h-TEG of postanhepatic 10 minutes was done. We obtained CL 60 (clot lysis 60) and MA (maximum amplitude) among the TEG parameters and counted the total number of packed red cell transfused before and after the reperfusion period. Results: The results showed that the experimental group had significantly higher value of CL 60 and MA in the h-TEG of postanhepatic 10 minutes and lower amount of packed red cell transfusion during the period after the reperfusion. Conclusions: The administration of low dose aprotinin during preanhepatic period reduced the activation of fibrinolysis and the total packed red blood cell transfusion after the reperfusion in liver transplantation.

      • KCI등재

        P파 속도 토모그래피를 이용한 터널 주변의 암반손상 평가

        박철수,목영진,김대영,사공명 한국지반공학회 2009 한국지반공학회논문집 Vol.25 No.11

        Construction of a tunnel induces rock masses damage around the tunnel. The degree of damage produced on rock masses will affect on the mechanical and hydraulic behaviors of the rock masses. In this paper, P wave velocity measured by cross-hole test was used to assess rock masses damage around the test tunnel. Initiation of source signal was carried out using mechanical impact at the source installed borehole. In consequence, the generated P wave signal was low noise and apparent wave form, which allows accurate pick-up of first arrival time. From the test, the region where rock damage is expected shows relatively low P wave velocity. In addition, with multiple points of P wave velocity measurement along each cross-hole, two dimensional P wave tomography was obtained. The tomography provides apparent view of the rock damage behind the tunnel. The measured P wave velocity was correlated with features of rock masses, porosity and Q value.

      • KCI등재

        부유식 해상구조물의 계류를 위한 사질토 지반의 석션파일 설계

        박철수,이주형,백두현,도진웅 한국지반공학회 2014 한국지반공학회논문집 Vol.30 No.10

        The preliminary design of suction pile as the supporting system for concrete floating structures was performed forthe pilot project of the southwest coast area in Korea. Prior to starting design work, site conditions of the area includingground and hydraulic conditions, and a 100-year return period external force were throughly evaluated. The suction pilefor mooring of the offshore floating structures has to satisfy the lateral resistance against external force as well as thepenetration ability according to the soil conditions such as soil types, shear strengths, effective stresses, and seepageforces. In the design, the required penetration depths, which were stable for lateral resistance, were evaluated with thediameters of cylindrical suction pile as the final installing ones. And the design suction pressures at each penetratingdepths, at which sand boiling did not occur, were assessed through the comparison of penetration and penetrationresistanceforces. As a result, it was impossible for suction piles with the diameter range of 3.0~5.0 m to penetrateinto required penetration depths. On the other hand, suction piles with the diameter range of 6.0 m and 7.0 m satisfiedboth the horizontal stability and the penetration ability by design suction pressures at the required penetration depthsof 8.5 m and 8.0 m, respectively.

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