소세포 폐암환자에서의 치료에 따른 뇌하수체 - 부신피질계의 변화

박석준(Suk Joon Park),이승헌(Seung Hun Lee),김양리(Yang Ree Kim),김영균(Young Kyoon Kim),송정섭(Jeong Sup Song),이광우(Kwang Woo Lee),박성학(Sung Hak Park) 대한내과학회 1992 대한내과학회지 Vol.43 No.3

N/A Background. Small cell carcinoma of the lung can produce many ectopic hormones, and most frequently ectopic ACTH. The change of the pituitary-adrenal axis is shown more frequently than the ectopic ACTH production, and its squential check reveals some prognostic significance. Methods. We evaluated the 13 patients with small cell carcinoma of the lung, who treated with combined chemotherapy and radiotherapy. The basal ACTH and cortisol, mid-night cortisol, and cortisol after ACTH stimulation were measured at each admission by RIA during 6-kur of chemotherapy. Results. 1) There were 5patients who lost the diurnal variation of serum cortisol. They were all responded to the scheduled treatment, partially or completely. At the same time they recovered from the loss of diurnal variation simultaneously with the therapeutic responses. 2) Non-responders to the ACTH stimulation were 6patients. 2patients among them showed abnormal response initially, but returned to normal response to the ACTH stimulation simultaneously with the response during treatment. Other 4patients showed normal response to the ACTH stimulation initially, but beacame to no response during treatment and finally turned out to normal Cortisol response. Conclusions. Thre are more changes in the pituitaryadrenal axis despite of normal ACTH and cortisol level, and these changes become normalized in almost all of the therapeutic responders.

사상의학과 인문학의 역할

박석준(Park Suk-Joon) 예문동양사상연구원 2009 오늘의 동양사상 Vol.- No.20

사상의학은 임상적으로만이 아니라 무엇보다도 인간관계를 이해하기 위해 매우 중요한 자료를 제공하고 있다. 그러나 지금까지는, 모든 연구의 출발점이 되는 용어상의 문제에서부터 철학적인 문제까지, 가장 기본적인 연구조차 매우 미흡한 실정이다. 이제마의 언어는 19세기의 언어 전통에 바탕을 두고 있으면서도 그의 용법은 매우 독특하여, 기존의 장부 개념과는 별 관계가 없는 새로운 폐비간신이라는 개념을 만들어 쓰고 있다. 장부의 개념만이 아니라 감정 등 거의 모든 용어가 이제마의 독자적인 용어로 변모하고 있다. 이런 점에서 19세기를 중심으로 한 인문학의 사상의학 연구에의 적극적인 참여가 요청되고 있다.

한의학의 인식론적 특징

박석준(Suk-joon Park) 한국의철학회 2006 의철학연구 Vol.1 No.-

이제마 천기론의 구조(1)

박석준(Suk-Joon Park) 한국의철학회 2007 의철학연구 Vol.4 No.-

이 논문은 이제마 사상의학의 출발을 이루는 천기의 개념에 대해 그 역사적 연원을 추적한다. 지금까지 천기에 대한 연구는 문학을 중심으로 이루어져 왔을 뿐 의학에서 천기는 본격적으로 논의되지 않았다. 따라서 천기 개념의 연원이 어디에 있는지, 그리고 그 개념은 어떻게 변천해왔으며 특히 조선 후기의 사회에서 어떻게 받아들여지고 있었는지에 대해 알아본 다음 그것이 이제마에게 어떻게 수용되고 있는지를 연구한다. 본고는 조선시대에 이루어진 철학적 성과, 특히 사단칠정(四端七情)과 연관된 논쟁이 성정론과 이기론의 종합이라는 과제를 수행한 것이라면 김창협을 거쳐 이루어진 성정론과 천기론의 ‘절충’이 이제마에게서 종합되어 그의 독특한 ‘성명론’을 만들었다는 가정을 증명할 것이다. 1. Objectives Lee Jema's Cheonki Theory is the starting point of his Sasang theory and also is the most basic structure of his theory. Until now there is rare studies on this subject. To study Leejema's Cheonki Theory on historical and philosophical(conceptual) base is our purpose. 2. Method of Research First, we examine the history of Seongjeong Theory(性情論) which theorize human nature and it's representation both in China and Chosun. Secondly we examine Cheonki Theory of Taoists and Confucian scholars in China. 3. Result Cheonki Theory is developed from Seongjeong Theory. It arises from the contradiction of Seongjeong Theory which and tries to solve the problem. The contradiction reflects the rise of need of personals and the middle class especially in middle and late feudal society. 4. Conclusion Lee Jema's Cheonki Theory is the synthesis of Seongjeong Theory and Cheonki Theory. And it is the bodied synthesis of Seongjeong Theory aiming the harmonious order both in society and body.

한의학의 몸

박석준(Suk-joon Park) 한국의철학회 2006 의철학연구 Vol.2 No.-

자궁근종(子宮筋腫) 및 난소낭종(卵巢囊腫)으로 진단(診斷)받은 소양인(少陽人) 환자(患者) 치험예(治驗例)

이정환,박석준,구덕모,이상민,서은희,Lee, Jung-Hwan,Park, Suk-Joon,Goo, Deok-Mo,Lee, Sang-Min,Seo, Eun-Hee 사상체질의학회 2005 사상체질의학회지 Vol.17 No.1

1. Objectives Uterine myoma and Ovary cyst is a common disease in gynecologist. These disease can also be treated by Sasang constitutional medical diagnosis and treatment. 2. Methods In treatment of the patient who has Uterine myoma and Ovary cyst, we had diagnosed her as soyangin by their own characters and prescribed Gamijihwang-tang(加味地黃湯). 3. Results The scale of Uterine myoma and Ovary cyst reduced and the occured syndrome with that disease was diasppeared 4. Conclusions In conclusion, this paper shows that the treatment and healing process of Uterine myoma and Ovary cyst.

측면주사소나 특성에 따른 자율무인잠수정 기뢰탐색 효과도 분석

유태석,박석준,윤선일,박호규,Yoo, Tae-Suk,Park, Seok-Joon,Yoon, Seon-Il,Park, Ho-Gyu 한국정보통신학회 2020 한국정보통신학회논문지 Vol.24 No.8

부설된 기뢰를 소해하기 위해 기뢰매설 예상구역에 대한 탐색을 수행한다. 이 때 기뢰탐색은 기뢰의 위험성, 아군의 안정성 등을 고려하여 자율무인잠수정을 이용한다. 매설된 기뢰를 식별하기 위한 소나시스템은 측면주사소나, 합성개구소나 등을 탑재한다. 본 논문은 측면주사소나 특성에 따른 기뢰탐색효과도 분석에 대해 기술한다. 각 측면주사소나의 특성을 바탕으로 음향조사역 및 인식확률을 모델링 하였고, AUV의 주행패턴에 따라 분석을 수행하였다. AUV의 주행패턴은 측면주사소나 음영구역의 유무에 따라 3가지 탐색패턴을 정의하였다. 분석결과는 각 탐색패턴 마다 탐지시간, 탐지확률을 도출하고 최종적으로 측면주사소나 음영구역의 유무에 따른 탐색 향상도를 도출하였다. In order to Mine Countermeasure (MCM), the search is carried out for the expected mine zone. At this time, mine hunting uses Autonomous Unmanned Vehicle(AUV), taking into account the danger of mine and the stability of our forces. Sonar system for identifying buried mines are equipped with Side Scan Sonar(SSS) or Synthetic Aperture Sonar(SAS). This paper describes the analysis of mine hunting effects according to the commercial SSS characteristics. Based on the characteristics of each SSS, the insonified area and recognition probability were modeled, and the analysis was performed according to the search pattern of the AUV. AUV's search pattern defines three patterns depending on the presence or absence of SSS or shaded areas. The analysis results derived search time and detection probability for each search pattern, and finally, the improvement of search depending on the presence or absence of side injection or shaded area.

Allergy 비염 환자에서 분리된 Klebsiella pneumoniae 289에 대한 소음인(少陰人) 보중익기탕(補中益氣湯), 곽향정기산(藿香正氣散) 및 궁귀향소산(芎歸香蘇散)의 항균효과

서지용,서은희,박석준,구덕모,Suh, Ji-Yong,Seo, Eun-Hee,Park, Suk-Joon,Goo, Deok-Mo 사상체질의학회 2004 사상체질의학회지 Vol.16 No.3

1. Objectives Although the incidence of allergic rhinitis is increasing continually, Sasang Constitutional Medicine is showing favorable treatment outcomes. This study was aimed to test the antimicrobial effects of Bojungikgi-tang, Gwakhyangjeonggi-san, and Gunggwihyangso-san which are being applied to allergic rhinitis of Soeumin. 2. Methods Klebsiella pneumoniae 289 was extracted from allergic rhinitis patients. Bojungikgi-tang, Gwakhyangjeonggi-san, and Gunggwihyangso-san were boiled down and concentrated, and the substances obtained were tested for the effects on stability to temperature and pH and on antimicrobial activity 3. Results When measured the level of antimicrobial activity, the inhibition zones of Bojungikgi-tang, Gwakhyangjeonggi-san, and Gunggwihyangso-san were found 11.42, 11.07, and 10.63mm, respectively. The levels of MIC were $15{\mu}{\ell}$, $20{\mu}{\ell}$, and $10{\mu}{\ell}$ in that order. The antimicrobial activities were increased 13.88% in Bojungikgi-tang, 16.63% in Gwakhyangjeonggi-san, and 10.72% in Gunggwihyangso-san. There was no influence of pH to antimicrobial activity of all three substances. 4. Conclusions Bojungikgi-tang, Gwakhyangjeonggi-san, and Gunggwihyangso-san had a high level of antimicrobial activity to Klebsiella pneumoniae 289 even at a low concentration.

사상체질별 혈중 호모시스테인에 관한 연구

서은희,하진호,서영호,박석준,구덕모,이정환,Seo, Eun-Hee,Ha, Jin-Ho,Seo, Young-Ho,Park, Suk-Joon,Goo, Deok-Mo,Lee, Jung-Hwan 사상체질의학회 2006 사상체질의학회지 Vol.18 No.1

1. Objectives The purpose of this research is to find out the Constitutional difference between the amount of Plasma Homocysteine, Total cholesterol, and Triglyceride which are factor of Cerebrovascular disease. 2. Methods We enrolled 132 patients inexperienced Strokes who visited our hospital for a medical examination from April 26, 2004 to June 29, 2005 except patients whose body constitusions were undetermined according to QSCOII. This research investigated the Constitutional difference between the amount of Plasma Homocysteine, Total cholesterol and Triglyceride. 3. Results & Conclusions This research has shown that there is a statistical significance between the average amount of Plasma Homocystein level that is higher in Taeumin. But there is no significant difference between the average amount of Total Cholestrol and Triglyceride in Sasang Constitution.

비선형 모델에서의 선형화모델 기법의 응용

장영우(Young-Woo Chang),박석준(Suk-Joon Park) 한국정보과학회 1992 한국정보과학회 학술발표논문집 Vol.19 No.2

다변량 함수계에서의 제로점 계산, 최대 (최소) 치 계산, 비선형의 회귀분석 등에 사용될 수 있는 선형화 모델 기법은 편미분, 행렬 연산, 그리고 이들의 반복 계산을 적절히 활용하여 원하는 해를 구할 수 있다. 선형화 모델 기법의 장단점과 위에 예를 든 모델들에서의 활용 예를 예제와 함께 기술하였다.