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Cu-Sn 10 w/o 계의 소결에서 원료동분말의 산화피막이 치수변화에 미치는 영향
민경준,이방식,이도재 대한금속재료학회(대한금속학회) 1982 대한금속·재료학회지 Vol.20 No.7
The effect of heating rate and oxide film on copper surface on the dimensional change during sintering Cu-10% Sn compact and possible mechanism for the abnormal expansion near the peritectic temperature (798℃) are suggested. Two kinds of copper powders, reduced powder and oxidized powder, are used in this experiment in order to investigate the effect of oxide film on copper surface on the dimensional change of Cu-Sn transient liquid phase sintering. According to these experimental observation, the dimensional change is strongly depended upon the amount of localized tin-rich liquid phase during sintering. The more localized tin-rich liquid phase result in more dimensional expansion. In the case of specimen which is prepared with oxidized copper powder, the dimensional expansion is smaller than that of specimen prepared with reduced copper powders. It is apparent that the thin film of copper oxide on copper powder makes easy the flowing of tin-rich liquid through the interparticles of copper which may reduce the amount of localized tin-rich phase and resulted smaller dimensional expansion subsequently.
한국형 양극성 장애 약물치료 알고리듬 2006(Ⅲ):우울 삽화
민경준,박원명,서정석,하규섭,전덕인,이은,권준수,정상근,윤보현,김원,신영철,조현상 대한정신약물학회 2006 대한정신약물학회지 Vol.17 No.5
Objective: In 2002, publication of Korean Medication Algorithm Project for Bipolar Disorder (KMAP-BP 2002) made a clinical guidelines to understand and treat a bipolar disorder, but due to recent reports of various study and application of new drugs, the revision of treatment algorithm were inevitable. Therefore, we revised KMAP-BP 2006 focused on the treatment strategies of bipolar depression. Method: The methods to survey were similar to those of KMAP-BP in 2002. The review committee were consisted of 70 experienced psychiatrists. Among the total 37 questions, 15 questions for bipolar depression were evaluated. We classified the expert opinion to 3 categories based on the lowest category in which the confidence interval fell (6.5≤ for first-line and 3.5≤ for second-line treatment). Results: Compared to previous algorithm, combination of mood stabilizer(MS) or atypical antipsychotics(AAP) and antidepressants was generally more recommended than antidepressants monotherapy in bipolar depression. Lithium and divalproex were the first-line choice as MS. The preference for lamotrigine was increased, while carbamazepine decreased. Olanzapine and quetiapine were preferred as the first-line AAP. Most antidepressants were not recommended as first-line drug. The strategy for breakthrough depression was changed to adding antidepressant after combination of 2 MS. Conclusion: These results suggested that the treatment of bipolar depression would be different from those of unipolar depression. This algorithm would represent a significant advance and be useful and practical in treatment of bipolar depression. 2 002년도 연구에 비하여 보다 다양한 종류의 약물이 사용되고 있으며 치료전략에서도 항우울제의 사용과 기분조절제의 사용 전략에 변화가 있었다. 이러한 변화를 빠르고 적절하게 반영한 치료 지침을 제작하는 것은 효과적인 새로운 치료 방법을 임상에 빨리 적용할 수 있는 좋은 방법이다. 향후 더 많은 연구 자료와 임상적용의 결과를 통해 더욱 효과적인 치료전략이 개발될 때까지 본 연구 결과가 양극성 장애 환자의 치료에 많은 도움이 되기를 기대한다.
지리정보시스템과 빅데이터 분석 시스템을 활용한 관광 정책수립 방안 -인천광역시 주요 관광지 중심으로-
민경준,임희석,Min, Kyoungjun,Lim, Heuiseok 한국융합학회 2021 한국융합학회논문지 Vol.12 No.8
본 연구는 지리정보시스템과 빅데이터 분석 시스템을 활용하여 관광객 유입동향 및 소비패턴 분석에 목적을 둔 연구이다. 인천광역시 주요 관광지 중 송도센트럴파크와 차이나타운을 선정하여 2017년 6월 1개월 동안 유동인구 분석, 카드매출 분석을 진행하였다. 전국 광역시도로부터 송도센트럴파크에 방문한 관광객은 인천광역시, 경기도, 서울특별시 순으로 높게 나타났으며, 외국인 관광객 비중은 중국이 가장 높았다. 차이나타운 관광객의 카드 소비 이용건수는 남성이 여성보다 12.4% 높게 나타났고 카드소비 금액도 남성이 18% 높게 나타났다. 본 연구는 관광객들의 유입동향 및 소비패턴을 분석하여 관광정책 수립의 주요 쟁점들을 도출함으로써 관광정책의 전략적 방안을 제안하는데 시사점이 있다. 본 연구를 바탕으로 향후 관광 인프라 구축 개선에 도움이 될 수 있다고 기대된다. This study aims to analyze tourist inflow trends and consumption patterns using a geographic information system and big data analysis system. Songdo Central Park and Chinatown were selected among the major tourist destinations in Incheon, and floating population analysis and card sales analysis were conducted for one month in June 2017. The number of tourists visiting Songdo Central Park from metropolitan cities across the country was highest in the order of Incheon Metropolitan City, Gyeonggi-do, and Seoul Metropolitan City, and the proportion of foreign tourists was the highest in China. The number of card consumption used by Chinatown tourists was 12.4% higher for men than for women, and the amount of card consumption was also higher for men by 18%. This study has implications for proposing a strategic plan for tourism policy by analyzing the inflow trend and consumption pattern of tourists and deriving major issues in the establishment of tourism policy. Based on this study, it is expected that it can be helpful in improving the construction of tourism infrastructure in the future.
카드뮴 급성폭로에 의한 Metallothionein 생성과 독성작용
민경준,박정덕,홍연표,장임원,Min, Kyung-Joon,Park, Jung-Duck,Hong, Yeon-Pyo,Chang, Im-Won 대한예방의학회 1993 Journal of Preventive Medicine and Public Health Vol.26 No.2
Thirty five male Sprague-Dawley rats were treated with cadmium chloride solution ranging from 0.2 to 3.2mg $CdCl_2/kg$ by intravenous single injection. At 48 hours after administration of cadmium, total cadmium, MT bound cadmium and histopathologic finding in liver, kidney, lung, heart, testis, metallothionein in liver, kidney and total cadmium in bleed were examined. Tissue cadmium concentration was highest in liver, followed by in kidney, heart, lung and testis. Cadmium bound to rnetallothionein (MT-Cd) and ratio of MT-Cd to total cadmium were increased in liver and kidney dependently of cadmium exposure dose, but not significantly changed in other organs. On histopathologic finding, the most susceptible organ was heart in considering cadmium exposed dose, but testis in considering cadmium concentration. Blood cadmium concentration was increased with dose-dependent pattern, and significantly correlated with tissue cadmium concentration, so that we may estimate tissue cadmium concentration by measurement of blood cadmium concentration. Metallothionein in liver and kidney was increased with dose-dependent pattern, higher in liver than in kidney, and was significantly correlated with tissue cadmium concentration. However, metallothionein induction efficiency of tissue cadmium(${\mu}g\;MT/{\mu}g\;Cd$) was eater in liver than in kidney, and reverse to tissue concentration or exposed dose of cadmium.