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김태인,정지원,최재완,김운정,이지원,김윤서,천경진,배선규,김지유,채우리,정재원,송규석,이해솔,박정수,이주아,김영지,공경환,고호연,Kim, Tae-in,Chung, Ji-won,Choi, Jae-wan,Kim, Eun-jung,Lee, Ji-won,Kim, Yun-seo,Chun, Gyung-jin,Bae, Sun-kyu,Kim, Ji-yu,Chae, Woo 대한한방내과학회 2016 大韓韓方內科學會誌 Vol.37 No.6
Objectives: Strokes have diverse symptoms and signs. One of ten stroke patients has chronic pain after a stroke. Pain after a stroke interrupts rehabilitation and worsens quality of life, but there is no efficient treatment for this pain. This study surveyed and reports on the clinical studies of treatment for chronic pain after a stroke. Methods: We searched journals for reports on clinical studies of treatment for chronic pain after a stroke through the databases OASIS (http://oasis.kiom.re.kr), NDSL (ndsl.kr), Kmbase (http://kmbase.medric.or.kr/), and PubMed (http://www. pubmed.com). The search words were "stroke & pain", "jungpung中風 & pain", "pungbi風痺", "cerebral hemorrhage & pain", and "cerebral infarction & pain". Results: Twenty-nine studies of treatment for chronic pain after a stroke were found. Of these, 15 were randomized controlled trials, 10 were nonrandomized controlled trials, and 4 were "before and after" studies. Treatments were diverse, including acupuncture, electroacupuncture, herbal acupuncture, herbal medicine, and more. The treatment periods were longer than 3 weeks on average. Conclusions: These results show that good quality randomized controlled trials of treatment for chronic pain after a stroke are small in number. We need larger and more diverse studies of treatment for chronic pain after a stroke.
${\beta}$-Nitrostyrene에 대한 Nucleophilic Addition Constant의 측정 (I)
김태인,최영상,Kim, Tae-Rin,Choi, Young-Sang 대한화학회 1966 대한화학회지 Vol.10 No.4
여러가지 nucleophile을 써서 3,4-methylene-dioxy-${\beta}$-nitrostyrene에 대한 nucleophilic addition constant를 측정하여 이미 알려진 nucleophilic substitution constant와 비교해 보았더니, 이 둘 사이에는 비례관계가 성립되지 않으리라 생각된다. 이것을 정량적으로 취급하려면 앞으로 많은 nucleophile에 대해서 더욱 정확한 실험치를 얻을 수 있어야 하겠다. The nucleophilic addition constants 3,4-methylenedioxy-${\beta}$-nitrostyrene were determined for various nucleophiles. Considerably more data would be desirable, but it appears at present that there is no proportionality between the nucleophilic addition and substitution constant.
가토의 경골에 이식된 새로운 티타늄계 합금 주위의 골형성에 관한 형태학적 연구
김태인,Kim, Tae-In 대한치과보철학회 1998 대한치과보철학회지 Vol.36 No.5
Research advances in dental implantology have led to the development of several different types of materials and it is anticipated that continued research will lead to advanced dental implant materials. Currently used pure titanium has relatively low hardness and strength which may limit its ability to resist functional loads as a dental implant. Ti-6Al-4V also has potential problems such as corrosion resistance. osseointegration properties and neurologic disorder due to aluminium and vanadium, known as highly toxic elements, contained in Ti-6Al-4V. Newly developed titanium based alloys(Ti-20Zr-3Nb-3Ta-0.2Pd-1In, Ti-20Zr-3Nb-3Ta-0.2Pd) which do not contain toxic metallic components were designed by the Korea Institute of Science and Technology (KIST) with alloy design techniques using Zr, Nb, Ta, Pd, and In which are known as non-toxic elements. Biocompatibility and osseointegration properties of these newly designed alloys were evaluated after implantation in rabbit femur for 3 months. The conclusions were as follows : 1. Mechanical properties of the new designed Ti based alloys(Ti-20Zr-3Nb-3Ta-0.2Pd-1In, Ti-20Zr-3Nb-3Ta-0.2Pd) demonstrated close hardness and tensile strength values to Ti-6Al-4V. 2. New desinged experimental alloys showed stable corrosion resistance similar to the pure Ti but better than Ti-6Al-4V. However, the corrosion rate was higher for the new alloys. 3. Cell culture test showed that the new alloys have similar cell response compared with pure Ti and Ti-6Al-4V with no cell adverse reaction. 4. New designed alloys showed similar bone-metal contact ratio and osseointegration properties compared to pure Ti and Ti-6Al-4V after 3 months implantation in rabbit femur. 5. Four different surface treatments of the metals did not show any statistical difference of the cell growth and bone-metal contact ratio.
Dental Implant 금속재료의 성분차이에 따른 세포독성에 관한 연구
김태인,한준현,이인석,이규환,신명철,최부병,Kim, Tae-In,Han, Jun-Hyun,Lee, In-Seok,Lee, Kyu-Hwan,Shin, Myung-Chul,Choi, Boo-Byung 대한치과보철학회 1996 대한치과보철학회지 Vol.34 No.4
Today, dental implants are an acceptable alternative, capable of providing bone-anchored fixed prostheses for improved quality of life and self esteem for many patients. Research advances in dental implantology have led to the development of several different types of materials, and it is anticipated that continued research will likewise lead to advanced dental implant materials. Currently used pure titanium has relatively low hardness and strength which possibly limits its ability to resist the functional loads as a dental implant. Ti-6Al-4V also has potential problems such as corrosion resistance, bone biocompatibility etc. The carefully selected Zr, Nb, Ta, Pd, In constituents could improve mechanical strength, corrosion resistance, and biocompatibility compared to that of currently used implant metals. On the basis of the totality of the data from our study, it can be concluded that new titanium alloys containing Zr, Nb, Ta, Pd, In are able to provide improved mechanical properties, corrosion resistance and biocompatibility to warrant further investigation of it's potential as new biomaterials for dental implants.