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김재하,Kim, Jae-Ha 대한약리학회 1994 대한약리학잡지 Vol.30 No.2
In rat atrium the characteristics of purinergic receptors were investigated by observing the effects of some purinergic receptor agonists and antagonists on action potential and contractile force. The statistically significant effects of $ATP(10^{-6}{\sim}10^{-3}M)$ and adenosine $(10^{-6}{\sim}10^{-3}M)$ on normal action potential characteristics were a dose-dependent shortening of action potential duration $(APD_{90})$ by both agents and hyperpolarization by $ATP(10^{-4},10^{-3}M)$. $CAP(10^{-8}{\sim}10^{-4}M)$, an $A_1$ adenosine receptor agonist, shortened $(APD_{90})$ markedly in a dose-dependent manner and these effects were almost abolished by $DPCPX\;(10^{-6}\;M), an $A_1$, adenosine receptor antagonist, but not affected by $DMPX(2{\times}10^{-6}\;M)$, an $A_2$ adenosine receptor agonist. On the other hand, CGS $21680(10^{-7}{\sim}10^{-4}M)$, an $A_2$ adenosine receptor agonist, elicited a slight shortening of $(APD_{90})$ and these effects were inhibited by DPCPX but persisted in the presence of DPMX. Adenosine $(10^{-6}{\sim}10{\-4}\;M)$ decreased the basal contraction of atrial muscle in a dose-dependent manner and these effects were not inhibited by DMPX but by DPCPX. These results suggests that purinergic receptor agonists depress the cardiac activity by a short ening of action potential duration and this effect is mostly mediated by $A_1$ adenosine receptors in rat atrium.
웹 2.0 환경의 새로운 디지털 콘텐츠 서비스 전망에 관한 연구
김재하(Jae-Ha Kim) 한국방송·미디어공학회 2007 방송공학회논문지 Vol.12 No.5
The Internet is encountering a new turning point owing to the raising Web 2.0. A user just receives the information and service provided by a service provider in the existing web 2.0, but a user can create a new service for himself using an application program and data provided in web 2.0. The digital content market is producing a new service according to Web 2.0. The specific service among them is User Created Contents(UCC) and it is leading to the participation and interesting of user. SecondLife also which is the type as Social Network Service(SNS) and VR, is placing as a new service type. This paper defines Web 2.0 environment and classifies as UCC, SNS and Virtual Reality(VR) and defines a variety services shown in new environment. It also analyzes shortcomings and then prospect a new type of service which will be shown in the future.