4대 중증질환자의 정서적 스트레스와 명리학적 선천성 질환에 관한 연구

김일신(Kim, Il-Sin),조성제(Cho, Sung-Je) 한국산학기술학회 2013 한국산학기술학회논문지 Vol.14 No.8

본 연구의 목적은 요양시설 입소노인의 중증질환자와 명리학적 선천성질환의 상관관계, 스트레스 충격척도, 정서적 탈진척도 요인을 분석하고자 한다. 연구대상은 서울시에 소재하는 요양시설에 입소한 노인들 중에서 4대 중증 질환자의 147명을 대상으로 2013년 3월 15일부터 5월 31일까지 실시하였다. 연구방법은 빈도분석, 상관분석, 단순회 귀분석, t-test, 일원변량분석 등을 실시하였고, 실증분석은 모두 유의수준 5%에서 검증하였다. 분석결과 및 결론은 중 증질환 자와 명리학적 선천성질환의 상관관계가 높게 나타났으며, 중증질환 판정시 스트레스척도가 높게 나타났다. 그리고 스트레스 척도가 높을수록 정서적 탈진척도도 높게 나타났다. The objective of this study is to analyze the correlations between the chronic illnesses and congenital diseases of the chronic elderly invalids in nursing homes, as well as to examine the impact of stress scale and the factors affecting the emotional burnout scale. This study conducted Seoul survey from March 15 to May 31, 2013, targeting 147 seniors in nursing homes who were suffering from the four most common chronic illnesses. Analyses performed in this study include frequency, correlation and simple regression analyses, t-test and one-way analysis of variance, etc. All of the empirical analyses were conducted at 5% level of significance. The result of the study shows that there is a high correlation between the chronic invalids and their congenital diseases determined by the four pillars of destiny and that, if they are found to have a chronic illness, patients experience a high level of stress. Persons who score higher on the stress scale tend to score higher in the emotional burnout scale.

4대 중증질환자와 혈연 관계자에 대한 명리학적 선천성질환 특성요인 분석

김일신(Kim, Il-Sin),조성제(Cho, Sung-Je) 한국산학기술학회 2013 한국산학기술학회논문지 Vol.14 No.11

본 연구는 4대 중증질환자와 혈연 관계자에 대한 명리학적 선천성질환 특성요인을 파악하고자 한다. 연구기 간은 2013년 3월15일부터 7월31일까지이며, 연구대상자는 서울시에 소재하는 요양시설에 입소한 노인들 중에서 4대 중증질환자와 혈연 관계자에 대한 각각 147명을 대상으로 실시하였다. 자료 분석은 SPSS/WIN 18.0 프로그램을 이용 하여 빈도분석, 카이스케어 검정을 통계적으로 분석하였다. 연구결과는 4대 중증질환자와 혈연 관계자의 질환특성요 인이 매우 유사하게 나타났으며, 선천성질환 중에서 뇌혈관질환이 가장 유의미하게 나타났다. 그리고 혈연 관계자의 건강관련 특성요인에 따른 4대 중증질환자는 유의미한 차이가 있었다. 본 연구의 결과에 의한 시사점은 4대 중증질환 자와 혈연 관계자에 대한 명리학적 선천성질환이 유의미하게 나타났으므로 혈연 관계자의 질병예측기초자료가 될 것 으로 사료된다. The objective of this study is to identify key attributes to congenital disease factors regarding the patients of the four most-common serious chronic illnesses and their relatives in the light of Myeongrihak. For the purpose of this study, a survey was conducted from March 15 to July 31, 2013, of 147 elderly people with the four most-common serious chronic illnesses admitted to nursing homes located in Seoul. Data were analyzed by frequency analysis and Kai-square tests by use of SPSS/WIN 18.0. The analysis found that the patients and their relatives had very similar disease factors, and cerebrovascular diseases presented the strongest correlations. The subjects also showed meaningful differences according to the health factors of their relatives. As this study found that meaningful correlations regarding congenital diseases between patients of the four most-common serious chronic illnesses and their relatives in the light of Myeongrihak, this will serve as basic data to predicts health conditions of families and relatives.

한국인 전반적 급진성 치주염 환자에서 IL-6 유전자 다변성에 관한 연구

방선정,김일신,김옥수,김영준,정현주,Bang, Sun-Jung,Kim, Il-Shin,Kim, Ok-Su,Kim, Young-Jun,Chung, Hyun-Ju 대한치주과학회 2008 Journal of Periodontal & Implant Science Vol.38 No.4

Purpose: The purpose of this study was to investigate the association of generalized aggressive periodontitis with IL-6 promoter gene single nucleotide polymorphisms(SNP). Material and Methods: The study population consisted of 52 generalized aggressive periodontitis patients(GAP) and 30 periodontally healthy control subjects, who were systemically healthy non-smokers. Genomic DNA was obtained from buccal swab. The IL-6 promotor SNP at the positions of -597, -572, and -174 were genotyped by amplifying the polymorphic region using polymerase chain reaction(PCR), restriction enzyme digestion and gel electrophoresis. Result: The genotype distributions for G/G, G/A and A/A genotypes of IL-6 -597 were 30.8%, 40.4%, and 28.8% in the GAP group and 53.3%, 40%, and 6.7% in the control group and were statistically different between 2 groups(p<0.05). Allele 2 frequency of IL-6 -597 were significantly higher in the GAP group than the control group(p<0.01). At the position of IL-6 -572, the distribution for C/C, C/G and G/G genotypes were 23.1%, 55.8% and 21.2% in the GAP group and 20%, 33.3%, and 46.7% in the control group. In female subjects, the genotype distribution were significantly different between 2 groups(p<0.01). In male subjects, allele 2 frequency of IL-6-572 was significantly lower in the GAP group than the control group(p<0.05). The genotype distribution of IL-6 -174 in the GAP group were 96.2%, 3.8% for G/G, G/C genotypes whereas only the G/G genotype was detected in the control group. Conclusion: In conclusion, significant associations were found in IL-6 gene promoter(-597, -572) polymorphisms and generalized aggressive periodontitis. Further cohort study will be necessary in larger population.

당뇨병에서의 lipoprotein 분획에 대한 연구

문일신,김창세 순천향대학교 1993 논문집 Vol.16 No.2

There were studied on the diabetes mellitus, 121 patients, for determination of lipoprotein fractions and serum lipids and to so did as diabetes mellitus with circulatioty complications visiting to the Chunan Soonchunhyang Hospital. The results are obtained as followings: 1. The lipoprotein fractions in diabetes mellitus were shown as :a-LP 30.30 ±7.29%, pre-B-LP 22.94±11.93% and B-LP 46.59±8.59%. 2. Pearson correlation between serum triglyceride and lipoprotein fractions was shown significant, p>0.001, while serum total cholesterol was shown insignificant. 3. To compare between diabetes melitus without and with complication difference between both was not shown significant. While Pearson correlations between lipid and lipoprotein fractions were shown significant except-B-LP. 4. From above results the increments of total cholesterol and triglyceride in diabetes mellitus were prone to have a circulatory complications, and so it must be decrease to within normal limits for avoiding the circulatory complications, if necessary, by therapeutics.

간접 복합레진 합착 시 자가부식형과 자가접착형 레진시멘트의 상아질에 대한 미세인장 결합강도

박재구,조영곤,김일신 大韓齒科保存學會 2010 Restorative Dentistry & Endodontics Vol.35 No.2

본 연구는 간접 복합레진 수복물을 1종의 자가부식형 레진시멘트와 3종의 자가접착형 레진시멘트를 이용하여 상아질에 합착하였을 때 각 레진시멘트의 미세인장 결합강도와 결합계면의 차이를 평가하기 위하여 시행하였다. 발거된 상.하악 대구치 교합면 측 상아질에 Tescera 복합레진 블록을 레진시멘트(PA 군: Panavia F 2.0, RE 군: RelyX Unicem Clicker, MA 군: Maxem, BI 군: BisCem)를 이용하여 합착하였다. 증류수에 24시간 동안 보관한 후, 합착된 면의 단면적이 1.0 × 1.0 mm인 막대모양의 시편을 제작하여 각 시편에 분당 0.5 mm의 crosshead speed로 인장하중을 가하였다. 각 군의 미세인장 결합강도는 one-way ANOVA와 Tukey의 HSD 방법을 이용하여 비교하였다. FE-SEM 하에서 모든 파절편의 상아질 쪽 파절양상과 레진시멘트-상아질 및 레진시멘트-복합레진의 계면을 관찰하였다. 본 연구의 결과 간접 복합레진 블록을 레진시멘트로 상아질에 합착할 때 PA 군과 RE 군은 MA 군과 BI 군보다 높은 결합강도와 긴밀한 접착 및 레진테그가 관찰되었고, 복합레진과 레진시멘트 간에는 간극이 관찰되었다. The purpose of this study was to evaluate the microtensile bond strength (μTBS), failure modes and bonding interfaces of self-etching and three self-adhesive resin cements to dentin and indirect composite resin. Cylindrical composite blocks (Tescera, Bisco Inc.) were luted with resin cements (PA: Panavia F 2.0, Kuraray Medical Inc., RE: RelyX Unicem Clicker, 3M ESPE., MA: Maxem, Kerr Co., BI: BisCem, Bisco Inc.) on the prepared occlusal dentin surfaces of 20 extracted molars. After storage in distilled water for 24h, 1.0 mm × 1.0 mm composite-dentin beams were prepared. μTBS was tested at a cross-head speed of 0.5 mm/min. Data were analyzed with one-way ANOVA and Tukey’s HSD test. Dentin sides of all fractured specimens and interfaces of resin cements-dentin or resin cements-composite were examined at FESEM(Field Emission-Scanning Electron Microscope). In conclusion, PA and RE showed higher bond strength and closer adaptation than MA and BI when indirect composite blocks were luted to dentin using a self-etching and three self-adhesive resin cements.