식중독 원인 미생물 장기 보존 방법에 대한 고찰

김유진,김수민,김소연,윤요한,Kim, Yujin,Kim, Soomin,Kim, Soyeon,Yoon, Yohan 한국식품위생안전성학회 2022 한국식품위생안전성학회지 Vol.37 No.3

The rapid development of biotechnology has increased the importance of microorganisms or their genetic information. Thus, the Nagoya Protocol on access to genetic resources and the fair and equitable sharing of benefits arising from their utilization was established, and countries are working to secure industrially and academically useful bioresources to deal with the agreement. In the case of Korea, because 67% of bioresources are imported from abroad, we are required to secure domestic bioresources as well. The number of isolated foodborne illness-causing microorganisms is predicted to invrease based on the incresing number of outbreaks of foodborne illness each year. Consequently, appropriate long-term preservation methods are necessary to secure the isolated microorganisms for the purpose of research and resourcification. Therefore, the long-term preservation methods for bacteria, fungi, viruses, and protozoa were investigated in this study, from domestic and international bioresource banks, and the functions of the cryoprotectants were reviewed and discussed. This review should be informative in the preservation of microorganisms and contribute to the development of biotechnology.

3D 프린터 용 PLA/LDPE 고분자 블렌드 모노필라멘트

김유진,최혜미,신동수,김규식,장순호,오태환,Kim, Yu Jin,Choi, Hye Mi,Shin, Dong Soo,Kim, Gyu Sik,Jang, Soon Ho,Oh, Tae Hwan 한국섬유공학회 2018 한국섬유공학회지 Vol.55 No.3

In this study, the effects of a compatibilizer and the blend ratio of low-density polyethylene (LDPE) on the 3D printability of polylactic acid (PLA)/LDPE monofilaments were investigated. Two kinds of PLA and LDPE with different melt indices (MI) were selected for the PLA/LDPE blend monofilaments. An ethylene/butyl acrylate/glycidyl methacrylate terpolymer, having affinities for both PLA and LDPE, was used as a compatibilizer. The tensile strength of the PLA/LDPE monofilaments decreased with increasing amounts of LDPE. PLA with a lower MI of 6 showed better printability than PLA with higher MIs of 15-30, due to its higher viscosity. When the compatibilizer was added, the compatibility and 3D printability increased. The printability increased when the compatibilizer was added up to 20 wt.%, but decreased when LDPE was added at over 30 wt.%.

초음속 충돌 제트 운동에 대한 k-$\omega$ 난류모델의 적용

김유진,박수형,권장혁,김성인,박승오,이광섭,홍승규,Kim E.,Park S. H.,Kwon J. H.,Kim S. I.,Park S. O.,Lee K. S.,Hong S. G. 한국전산유체공학회 2004 한국전산유체공학회지 Vol.9 No.2

A numerical study of underexpanded jet and impingement on a wall mounted at various distances from the nozzle exit is presented. The 3-dimensional Wavier-Stokes equations and κ-ω turbulence equations are solved. The grids are constructed as overlapped grid systems to examine the distance effect. The DADI method is applied to obtain steady-state solutions. To avoid numerical instability such as the carbuncle phenomena that sometimes accompany approximate Riemann solver, the HLLE+ scheme is employed for the inviscid flux at the cell interfaces. A goal of this work is to apply a number of two-equation turbulence models based on the w equation to the impinging jet problem.

대학 기숙사의 만족도 향상을 위한 시설관리(FM) 서비스 제안

김유진,신은영,김준하,Kim, Yu-Jin,Shin, Eun-Young,Kim, Jun-Ha 한국교육시설학회 2016 敎育施設 Vol.23 No.2

University dorm basically provides basic housing functions to students, however, it is very important in a sense that it provides students with various functions such as information exchange, cultural experience and learning environments as well. Additionally, continuous effort to improve users' satisfaction and living environments are needed due to the fact that physical environments of dorm facilities have higher impact on students. However, Many students are not satisfied with the physical environment of university dorms and also there is lack of systematic information whereas various functions are required by students. Therefore, the main objective of this research is to suggest the direction of FM services in order for improving students' satisfaction on the university dorm facilities in Korea. Precedent studies regarding the satisfaction or performance evaluation of dorm facilities have been extensively analyzed to extract the dissatisfaction factors that scored below the middle 50%. Secondly, for satisfaction improvement, Korean Standard for Facility Management(KS_FM) have been matched with those extracted dissatisfaction factors to suggest the direction of FM services by rules and regulations review and best practice studies. This research will be useful for university dorm facility managers in planning strategic FM and providing effective FM services to students.

Collaborative Planning Model for Brownfield Regeneration

김유진,패트릭 밀러,Kim, Eujin Julia,Miller, Patrick Korean Institute of Landscape Architecture 2015 韓國造景學會誌 Vol.43 No.3

Unlike most other planning processes, brownfield planning generally requires a high level of technical and legal expertise due to potential site contamination. To successfully engage in inclusionary decision making, an adaptive collaboration strategy for brownfield planning is therefore critical. This study examines how a communicative planning approach can be used to overcome the challenge of enabling experts from different fields to work alongside lay people from the local community to achieve a properly balanced collaboration in brownfield planning. After identifying appropriate indicators for collaboration through a literature review of established communicative planning theory, these indicators are applied to the brownfield planning process, highlighting critical points of collaboration such as site prioritization, assessment, remediation, and redevelopment throughout. The results suggest the critical need for an adaptive model focusing on three aspects: 1. Facilitation of a balanced dialogue between the experts with social, cultural, and design-based knowledge and the ones with scientific and engineering-based knowledge, 2. Preparation of an appropriate tool for risk communication with the lay people, 3. Development of decision support system for the integration of expert-oriented technical data and public opinion-oriented subjective data. 대부분의 일반적인 계획 과정과 달리, 브라운필드 계획은 잠재된 오염문제로 인한 기술적, 법률적 전문지식을 필요로 한다. 성공적으로 통합적인 의사결정에 관여하기 위해서는 조정된 협력적 계획 모델이 중요하다. 본 연구는 기존의 협력적 계획 접근방식이 브라운 필드 재생에 있어 상반된 분야의 전문가들 및 지역 주민들이 함께 일하며 적절하게 균형 잡힌 협력을 이루어 내기 위한 어려움들을 극복하는 데에 어떻게 효과적으로 적용될 수 있는지 알아보는 것을 목표로 한다. 의사소통적 계획이론 관련 문헌분석을 통해 적절한 지표들을 찾아내어, 네 단계의 브라운 필드 계획과정(대상지 선별, 평가, 정화, 디자인)에 적용시켜 본 후, 중요한 부분들을 짚어내었다. 본 연구의 결과, 크게 세 가지 점에 초점을 맞춘, 브라운 필드 재생에 적합한 협력적 계획 모델의 필요성이 인식되었다(1. 사회, 문화, 디자인 분야와 과학, 기술 분야의 전문가 간의 균형 잡힌 대화의 촉진, 2. 일반주민들과의 잠재적 오염 위험과 관련한 커뮤니케이션을 위한 적절한 방법개발, 3. 전문가 주도의 객관적 데이터와 주민 의견 중심의 주관적 데이터의 통합을 위한 의사결정지원 시스템의 마련).

제1형 당뇨 환아를 위한 에듀테인먼트 콘텐츠 제안

김유진,김상아,윤희림,이진영,전혜빈,박수이,Kim, Yu-jin,Kim, Sang-a,Yun, Hee-rim,Lee, Jin-young,Jeon, Hye-bin,Park, Su-e 한국정보통신학회 2019 한국정보통신학회논문지 Vol.23 No.1

최근 의료 기술의 발달로 제1형 당뇨에 대한 진단율이 높아지면서 당뇨 환아가 증가하고 있다. 이러한 상황에서 환아들에게 당뇨 교육이 필요하지만, 효율적이고 적절한 교육 콘텐츠는 부재한 상황이다. 특히 이러한 교육은 혈당 변화 대처요령과 행동치료에 대한 꾸준하고 반복적인 학습이 필요하다. 따라서 본 연구에서는 10-11세 환아들의 눈높이에 맞춰 주도적으로 학습할 수 있는 에듀테인먼트 콘텐츠를 제안하고자 한다. 효과적인 학습을 위해 주사 실습콘텐츠를 구성하였고 반복적인 학습을 위해 하이브리드방식을 사용하였다. 사용성 테스트를 통해서 이러한 구성이 효과적임을 알 수 있었다. 본 연구는 상대적으로 당뇨 교육을 받기 어려운 지역의 환아들이 쉽게 접근 가능함과 동시에 앞으로 개발될 아동의 눈높이에 맞춘 당뇨 교육 콘텐츠 연구의 기반 연구로써 공헌할 것으로 기대된다. With the recent development of medical technology, the diagnosis rate of type 1 diabetes is increasing and patients are increasing. However, diabetes education content is not aligned with the interest level of children. As a result of the interviews with experts, It was found that the measures of coping with the change of blood sugar and the behavior therapy require steady and repetitive learning. Therefore, this study proposes Edutainment content which can be repeatedly Learned by 10~11year old children. For effective learning, the contents of the laboratory practice were constructed and the hybrid method was used for the repetitive learning. Usability test showed that this configuration is effective. This study is expected to contribute to the study of diabetic education content that is suitable for the children's level of understanding which will be developed easily in the future.

Quantitative Analysis on Cellular Uptake of Clustered Ferrite Magnetic Nanoparticles

김유진,Bum Chul Park,Young Soo Choi,고민준,Young Keun Kim 대한금속·재료학회 2019 ELECTRONIC MATERIALS LETTERS Vol.15 No.4

Due to their ability to be internalized into cells by endocytosis through cell membranes, the application of nanoparticlesin therapeutic and diagnostic fields has received much interest. In particular, ferrite magnetic nanoparticles (MNPs) arewidely used as reagents for medical care, including in vitro magnetic separation, T2-weighted magnetic resonance imaging,magnetic hyperthermia therapy, and as drug delivery systems. However, little is known about the quantitative analysis ofthe cellular uptake of MNPs by the interaction of particle surfaces with biomolecules. Here, we quantitatively analyze theintracellular uptakes of 30 nm Fe- and Mn-ferrite MNPs. We confirm that the magnetic properties of MNPs change accordingto their microstructure and quantitatively analyze nanoparticle internalization in breast cell lines (MCF10A, MCF7, andMDA-MB-231) by measuring the magnetic moment using a vibrating sample magnetometer. Finally, we examine the effectof nanoparticle microstructure on cellular uptake in terms of the interaction between the nanoparticles and biomolecules.

RICS-based DSP의 효율적인 임베디드 메모리 인터페이스

김유진,조경록,김성식,정의석,Kim, You-Jin,Cho, Kyoung-Rok,Kim, Sung-Sik,Cheong, Eui-Seok 대한전자공학회 1999 電子工學會論文誌, C Vol.c36 No.9

본 논문에서는 GMS30C2132마이크로프로세서에 DSP연산을 위하여 128K bytes EPROM과 4K bytes SRAM을 내장하고, 이 과정에서 내/외부 메모리 인터페이스 부분이 프로세서와 1싸이클 엑세스가 이루어지도록 버스 제어 인터페이스 구조를 설계하였다. 내장된 128Kbytes EPROM은 메모리 구조 및 데이터 정렬에 따른 동작을 위해 새로운 데이터 확장 인터페이스 구조와 테스트를 위한 인터페이스 구조를 제안하였으며, 내장된 4K bytes SRAM은 프로세서와 인터페이스를 할 때 DSP 고속 연산에 활용하기 위해 메모리 스택으로써의 이용과 명령어 캐쉬와의 인터페이스, 가변 데이타 크기 제어, 모듈로 4Kb의 어드레싱이 가능한 구조를 채택하여 설계하였다. 본 논문의 새로운 구조 적용으로 내장EPROM, SRAM에서 평균 메모리 엑세스 속도가 종전의 40ns에서 20ns로 감소하였고, 가변 데이타 버스 인터페이스 제어로 프로그램 처리 속도가 2배로 개선되었다. In this paper, we designed an embedded processor with 128Kbytes EPROM and 4Kbytes SRAM based on GMS30C2132 which RISC processor with DSP functions. And a new architecture of bus sharing to control the embedded memory and external memory unit i proposed aiming at one-cycle access between memories and CPU. For embedded 128Kbytes EPROM, we designed the new expansion interface for data size at data ordering with memory organization and the efficient interface for test. The embedded SRAM supports an extended stack area high speed DSP operation, instruction cache and variable data-length control which is accessed with 4K modulo addressing schemes. The proposed new architecture and circuits reduced the memory access cycle time from 40ns and improved operation speed 2-times for program benchmark test. The chip is occupied $108.68mm^2$ using $0.6{\mu}m$ CMOS technology.

하천관리를 위한 하천진단 및 시스템 개발

김유진,윤승호,박찬호,최원태,Kim, Yu-Jin,Yun, Seung-Ho,Park, Chan-Ho,Choe, Won-Tae 한국수자원학회 2016 물과 미래(한국수자원학회지) Vol.49 No.10

일개 호스피스 병동에서 임종한 말기 폐암 환자의 임상적 고찰

김유진,이춘섭,이주리,이정호,홍영화,이태규,문도호,Kim, Yu-Jin,Lee, Choon-Sub,Lee, Ju-Ri,Lee, Jung-Ho,Hong, Young-Hwa,Lee, Tae-Gyu,Moon, Do-Ho 한국호스피스완화의료학회 2007 한국호스피스.완화의료학회지 Vol.10 No.2

목적: 본 연구는 오늘날 증가추세에 있는 폐암 환자에게 보다 체계적이고 효율적인 호스피스 완화의료를 위한 기초자료를 제공하고자 호스피스 병동에서 임종한 말기 폐암 환자의 임상적 특성을 조사하였다. 방법: 2003년 3월 1일부터 2006년 12월 31일까지 샘 안양병원 호스피스 병동에서 말기 폐암으로 임종한 129명의 환자를 대상으로 하여 이들의 의무기록을 후향적으로 조사하였다. 수집된 자료는 실수와 백분율, 빈도와 중간 값으로 제시하였으며 호스피스 완화의료 동안의 생존기간은 SPSS 13.0의 Kaplan-Meier방법으로 분석하였다. 결과: 129명의 말기 암 환자 중 남자 93명(72%), 여자 36명(28%), 연령의 중간 값은 68세(범위 $37{\sim}93$세)이었다. 진통제를 복용하고 있었던 환자는 82명(64%)이었으며 그렇지 않은 환자는 47명(36%)이었다. 입원 이유는 호흡곤란이 47명(36%)으로 가장 많았고 이는 일반적으로 말기 암환자의 입원이유가 통증인 것과 다르게 나타났다. 호스피스 병동 입원 후 120명(93%)의 환자에게 마약성 진통제를 사용하였고 주사용 모르핀(103명, 80%)이 가장 많이 처방되었다. 진정제를 사용한 환자는 87명(67%)이었으며 미다졸람을 가장 많이 사용하였다(68명, 53%). 호스피스 완화의료 동안의 생존기간의 중간 값은 35일, 입원 일수의 중간 값은 24일이었다. 결론: 말기 폐암환자에서 호흡곤란의 조절은 매우 중요하며 말기 폐암 환자에 대한 호스피스 완화의료의 기간이 짧아서 효과적인 호스피스 완화의료를 위해서는 가족과 환자에게 지속적인 교육과 홍보가 필요하다고 생각된다. Purpose: The prevalence of lung cancer is increasing continuously these days. We studied clinical characters of the terminal lung cancer patients who had died in hospice units and our study is the basic report for efficient hospice and palliative care to the lung cancer patients. Methods: We retrospectively reviewed the medical records of 129 terminal lung cancer patients who had died in Sam Anyang Hospice Unit from March 2003 to December 2006. The survival days during the hospice and palliative care were analyzed using Kaplan-Meier method of SPSS 13.0. Results: There were 93 males (72%) and 36 females (28%), and median age of patients was 68 years (range $37{\sim}93$). Eighty two patients (64%) took analgesics, the others 47 (36%) not. The most prevalent reason for admission was dyspnea (47 patients, 36%) and it was different from the terminally ill cancer patients being hospitalized because of pain. And the most common symptom was general weakness (103 patients, 80%). One hundred twenty of the paitents (93%) were administered opioid analgesics, and IV morphine shots were mostly used (103 patients, 80%). Sedation was used in 87 patients (67%), and midazolam was mostly used (68 patients, 53%). The median survival in hospice and palliative care was 35 days and the median hospitalization was 24 days. Conclusion: It is very important to manage dyspnea in terminal lung cancer patients. The length of hospice and palliative care for the terminal lung cancer patients is still short. Therefore continuous education and promotion of hospice and palliative care is needed for an effective care for the patients, their families and doctors.