Change in the Gastro-Intestinal Tract by Overexpressed Activin Beta A

김미녀,김영일,조정희,Kelly E Mayo,조병남 한국분자세포생물학회 2015 Molecules and cells Vol.38 No.12

Originally, activins were identified as stimulators of FSH release in reproduction. Other activities, including secondary axis formation in development, have since been revealed. Here, we investigated the influence of activin βA on the body, including the gastro-intestinal (GI) tract. Initially, the activin βA protein was detected in the serum proportional to the amount of pCMV-rAct plasmid injected. The induced level of activin βA in muscle was higher in female than male mice. Subsequent results revealed that stomach and intestine were severely damaged in pCMVrAct- injected mice. At the cellular level, loss of parietal cells was observed, resulting in increased pH within the stomach. This phenomenon was more severe in male than female mice. Consistent with damage of the stomach and intestine, activin βA often led to necrosis in the tip of the tail or foot, and loss of body weight was observed in pCMVrAct- injected male but not female mice. Finally, in pCMVrAct- injected mice, circulating activin βA led to death at supraphysiological doses, and this was dependent on the strain of mice used. Taken together, these results indicate that activin βA has an important role outside of reproduction and development, specifically in digestion. These data also indicate that activin βA must be controlled within a narrow range because of latent lethal activity. In addition, our approach can be used effectively for functional analysis of secreted proteins.

평창군의 인구 및 토지이용 변화

김미녀 관동대학교 지리교육과 1986 關東地理 Vol.1 No.-

미용고등학교 학생들의 교과과정에 대한 태도 조사연구

김미녀,최상복,이정옥 慶山大學校 保健福祉硏究所 2003 保健福祉硏究 Vol.8 No.-

This study was conducted to examine aspects of classes and students' attitude with the classes at beauty high schools in order to provide basic data for development of the curriculum of the schools. The subjects of this study were 217 students at four beauty high schools in Daegu City and Kyungbuk province. The curricula of the schools were used to examine the current situation. The data were analyzed by Chi-Square test and regression analysis. The results of this study can be summarized as follows. Most high schools at which cosmotology is taught are vocational high schools. Beauty related classes are categorized and taught as vocational classes at the vocational high schools. Therefore, the students at the vocational high schools take both vocational classes and academic classes such as Korean language, English, mathematics, etc. The course requirement hours for three years at the beauty high schools are total 216 units in both common and vocational classes. The vocational classes covered 50% to 55% of the total units. The higher the grade is, the more the vocational classes are. The vocational classes focused on practical training more than theory. The classes at the beauty high schools covered all the beauty related fields. They include theory and practice of beauty, theory and practice of skin care, practice of make-up, public health science, human development, etc. According to socio-demographic characteristics of the respondents, 88.0% of them was female and 54.8% was the second grader. 34.0% of them entered the schools because they were interested in cosmotology and 52.0% entered the schools because they thought it was easy to get a job in the field of beauty. 39.0% of them entered the schools because they failed in entrance into academic high schools. 88.0% did not underwent an aptitude test before they entered the schools. 53.5% of them did not consider transferring to another field of study. 35.0% was interested in majoring on make-up and 34.1% was interested in majoring on hair. 19.4% of them was interested in majoring on skin care. Only 11.5% of the respondents replied that they were not proud of the study at the beauty schools. The pride level was significantly different by grade, entrance motive, and intention of transference to another field of study. 53.5% of them replied that they wanted to get a job in the field of beauty. 47.5% of the respondents hoped to have more practical training class hours than theory class hours. 45.2% of them also wanted to have more vocational classes than academic classes. 45.5% of them thought that teachers had to focus on education for obtaining certificate of qualification. 88.5% did not obtain the certificate of qualification. 73.7% of the students who did not obtain the certificate wanted to get it. Among factors concerning direction of education, the rate of divided vocational education with consideration of personal aptitude was highest (38.3%) Factors significantly influencing students' satisfaction with classes were satisfaction level with class system, contribution level to getting an occupation, interest level in practical training, intention of taking classes from private academies, preference level of vocational class hours, and understanding level of theory. From above results, it can be concluded that curriculum of beauty high schools must be systematically developed to cultivate beauty experts and specialize beauty high schools. The learning achievement level also need to be enhanced through providing intensive major courses.

의료서비스에서 환자만족의 선·후행변수의 구조적 관계

김미녀,정기한,오재신 한국산업경제학회 2009 산업경제연구 Vol.22 No.6

최근 우리나라는 의료시장의 경쟁격화와 의료서비스의 개방, 고객의 의료서비스에 대한 기대의 증가 등 의료 환경의 변화로 인해 의료시장의 단기적인 관계에서 장기적인 관계를 강조하는 방향으로 전환되고 있는 실정이다. 따라서 본 논문은 의료서비스 산업에서 성과제고를 위한 방안으로 환자만족에 중점을 두고 이의 영향요인들을 규명하고자 하였다. 먼저 환자만족에 영향을 미치는 요인으로 서비스품질 개념을 도입하였으며 유의한 정의 영향관계를 확인하였다. 그리고 서비스품질은 환자만족뿐만 아니라 기업이미지에도 긍정적인 영향을 미치는 것으로 나타나 서비스품질 관리의 중요성을 제시하였다. 또한 환자만족의 후행 요인으로 환자신뢰와 환자몰입, 그리고 재방문의도의 관계를 살펴보고자 하였으며, 그 결과 기존 선행 연구들에서 제시하고 있는 연구결과들을 뒷받침하는 분석결과를 보여주었다. 특히 관계품질 차원으로 고려한 환자신뢰와 환자몰입이 재방문의도에 미치는 영향에서 의료서비스의 특성상 환자신뢰보다는 환자몰입이 재방문의도에 영향을 미치는 중요 변수라는 점을 확인하였다. The purpose of this study is to analyze effect of health care service quality on hospital image, patient satisfaction, patient trust, patient commitment, and revisit intention. In the dimension of health care service quality, many factors affect patient's evaluation for patient satisfaction. They are categorized as five factors; tangibles, reliability, responsibility, assurance, and empathy. In conclusion, the results of this study supported the proposed conceptual framework overall. Therefore, we identified that health care service quality is the antecedent of hospital image and patient satisfaction, and the consequent variables of these are patient trust, patient commitment, and revisit intention.

Estrogen에 의한 MUP의 억제적 조절

조병남,김미녀 가톨릭대학교 자연과학연구소 1999 자연과학논문집 Vol.20 No.-

The major urinary protein (MUP) of mice that binds hydrophobic molecules known as pheromones is regulated by various hormones including growth hormone, testosterone and thyroxine. To investigate the role of estrogen, the female reproductive hormone, in the regulation of MUP, we analyzed the MUP in the hormone-replaced mice. When urine was analyzed during the estrous cycle, MUP was found slightly lower in estrus than in other stages in female mice. Higher level of MUP was found in the ovariectomized female mice. However, when the ovariectomized female mice were injected with 17β-estradiol 2 weeks after surgery and sacrificed at 1, 2 and 3 days after injection, the levels of MUP were decreased in the estrogen-treated mice. In male mice, castration did not reveal any effect on the MUP level whereas estrogen treatment 2 weeks after castration decreased the level of MUP. Taken together, estrogen regulated MUP negatively in mice regardless of sex, suggesting that estrogen emerges as another regulation factor for MUP, in addition to the already known factors.

의료서비스에서 환자만족의 선,후행변수에 관한 연구

정기한,김미녀,신재익 한국경영학회 2008 한국경영학회 통합학술발표논문집 Vol.2008 No.8

의료서비스 품질, 환자만족, 관계품질, 구전 간의 관계에 관한 연구

정기한,김미녀 한국고객만족경영학회 2008 고객만족경영연구 Vol.10 No.1

Today hospital institutions face the difficulties of survival and changing environment due to more market opening, higher consumers' requirements, and fierce competition. The marketing strategy of higher patient satisfaction is needed to survive hospital institutions. This paper is to investigate the relationship among service quality in hospital service, patient satisfaction, relationship quality, and word of mouth. The results demonstrate that service quality affects patient satisfaction, trust and commitment and that patient satisfaction affects trust, commitment, and word of mouth and that trust and commitment affect word of mouth positively. Therefore, the relationship among service quality in hospital service, patient satisfaction, relationship quality, and word of mouth is a positive circulation. Marketers of hospital institutions should create high service quality, which leads to high patient satisfaction and relationship quality, which lead to a positive word of mouth. 오늘날 의료시장의 개방과 의료기관 간의 경쟁이 심화되고 환자들의 의료서비스에 대한 욕구수준이 높아짐에 따라 의료기관의 생존문제가 이슈화되고 있다. 본 연구에서는 외래환자들을 대상으로 의료서비스품질, 환자만족, 관계품질인 신뢰와 몰입, 구전 간의 영향관계를 분석하여 마케팅의 전략적 시사점을 제시하고자 한다. 실증분석결과, 의료서비스품질은 환자만족, 신뢰, 몰입에 긍정적 영향을 미치고, 환자만족은 신뢰, 몰입, 구전에 긍정적 영향을 미치며, 신뢰와 몰입은 구전에 긍정적 영향을 미치는 것으로 나타나 이들 변수들 간에는 선순환구조관계가 있음을 알 수 있다. 따라서 의료기관들은 외래환자들의 신뢰와 몰입을 강화하여 긍정적 구전효과를 가져오기 위해서는 의료서비스품질과 환자만족의 관리와 개선에 모든 마케팅역량을 투입해야 한다.

의료서비스만족의 선후행요인에 관한 연구

정기한(Ki Han Chung),김미녀(Mi Nyeo Kim),신재익(Jae Ik Shin) 한국마케팅과학회 2006 한국마케팅과학회 학술대회 발표 논문집 Vol.- No.-

유아의 읽기ㆍ쓰기를 위한 교수방법에 관한 연구

고후순(Ko Hoo-Soon),김미녀(Kim Mi-Nyu) 경성대학교 인문과학연구소 2001 인문학논총 Vol.4 No.-

I have some result through this research, the Instructional Method for Children's Reading and Writing. First, Teacher's recognition needs for children's role who is leaner of reading and writing. Children take some knowledge about letter actively. So on teaching method on reading and writing must be systematic instructional strategies. It should not be simple functional education. Second, Linguistic development of children is quite different according to individual. then instruction-learning method has to be adapted that could appropriate development and individualizing. Third, Reading and writing is not achieve short time. Therefore they must be taught continuously. Teacher has to give variety experiences for children to get interest in letters. Fourth, Children's reading and writing should be start with meaningful situation for children. Also it has to achieve with natural method that appropriate development. Hence the method of teaching literature should be with play that approch reading and writing naturally. Fifth, Teacher has to get basic knowledge enough about language development process. So teacher can teach children consistently. And ideal instruction of reading and writing must be developed at educational field.

서비스산업 종사자의 시장지향성, 서비스품질, 고객만족에 관한 연구

정기한,정태석,신재익,김미녀 한국산업경영학회 2008 한국산업경영학회 발표논문집 Vol.2008 No.4

본 연구는 서비스산업 종사자의 시장지향성이 서비스품질의 각 차원에 미치는 영향과 그 차원의 각각이 고객만족에 긍정적인 영향을 미치는가에 대하여 실증분석 하여 개념적 구조를 제시하고자 한다. 전국 애프터서비스 업체를 대상으로 회수된 부수 중 371부의 설문지를 자료에 이용하였다. 실증분석에서 첫째, 시장지향성은 서비스품질의 공감성, 신뢰성, 유형성에 긍정적 영향을 미치는 것으로 나타났다. 둘째, 서비스품질의 공감성, 신뢰성은 고객만족에 긍정적인 영향을 미치고 있으나, 유형성은 영향을 주지 못하였다. 셋째, 시장지향성은 고객만족에 직접 영향을 주지 못하였으나, 간접적으로 높은 영향을 미치는 것으로 나타났다. 기술지향적 서비스산업 종사자의 시장지향성이 고객만족에 직접 영향을 주지 못하는 것이 매우 의미 있는 결과로 나타났다. 끝으로 가설검증 결과를 기초로 하여 학문적, 실무적 시사점과 향후 연구과제 등을 논하였다.